Result of FASTA (omim) for
pFN21AE1960
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1960, 522 aa
1>>>pF1KE1960 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7344+/-0.000442; mu= 16.6611+/- 0.027
mean_var=88.1375+/-17.731, 0's: 0 Z-trim(111.1): 101 B-trim: 187 in 1/55
Lambda= 0.136614
statistics sampled from 19474 (19575) to 19474 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.23), width: 16
Scan time: 9.370
The best scores are: opt bits E(85289)
NP_116759 (OMIM: 601762,603909,605027,613659) casp ( 522) 3432 687.1 3.4e-197
XP_005246964 (OMIM: 601762,603909,605027,613659) P ( 521) 3413 683.3 4.6e-196
NP_116756 (OMIM: 601762,603909,605027,613659) casp ( 521) 3116 624.8 1.9e-178
XP_006712859 (OMIM: 601762,603909,605027,613659) P ( 272) 1695 344.5 2.4e-94
NP_001221 (OMIM: 601762,603909,605027,613659) casp ( 479) 1695 344.7 3.7e-94
NP_116758 (OMIM: 601762,603909,605027,613659) casp ( 273) 1547 315.4 1.4e-85
NP_001193453 (OMIM: 601762,603909,605027,613659) c ( 455) 1547 315.5 2.1e-85
XP_011510292 (OMIM: 601762,603909,605027,613659) P ( 272) 1528 311.6 1.9e-84
NP_001293012 (OMIM: 601762,603909,605027,613659) c ( 247) 1469 299.9 5.6e-81
NP_001193471 (OMIM: 601762,603909,605027,613659) c ( 478) 1460 298.4 3.2e-80
NP_001219 (OMIM: 114480,114550,211980,601763,60727 ( 496) 825 173.2 1.6e-42
XP_005246942 (OMIM: 114480,114550,211980,601763,60 ( 523) 735 155.5 3.6e-37
XP_005246943 (OMIM: 114480,114550,211980,601763,60 ( 479) 733 155.1 4.4e-37
XP_005246948 (OMIM: 114480,114550,211980,601763,60 ( 479) 733 155.1 4.4e-37
XP_005246947 (OMIM: 114480,114550,211980,601763,60 ( 479) 733 155.1 4.4e-37
XP_006712852 (OMIM: 114480,114550,211980,601763,60 ( 479) 733 155.1 4.4e-37
XP_005246945 (OMIM: 114480,114550,211980,601763,60 ( 479) 733 155.1 4.4e-37
XP_005246944 (OMIM: 114480,114550,211980,601763,60 ( 479) 733 155.1 4.4e-37
NP_203519 (OMIM: 114480,114550,211980,601763,60727 ( 479) 733 155.1 4.4e-37
XP_006712853 (OMIM: 114480,114550,211980,601763,60 ( 479) 733 155.1 4.4e-37
XP_005246946 (OMIM: 114480,114550,211980,601763,60 ( 479) 733 155.1 4.4e-37
NP_001073594 (OMIM: 114480,114550,211980,601763,60 ( 538) 733 155.1 4.8e-37
XP_005246951 (OMIM: 114480,114550,211980,601763,60 ( 280) 709 150.2 7.6e-36
XP_005246949 (OMIM: 114480,114550,211980,601763,60 ( 464) 711 150.8 8.6e-36
NP_001073593 (OMIM: 114480,114550,211980,601763,60 ( 464) 711 150.8 8.6e-36
NP_203520 (OMIM: 114480,114550,211980,601763,60727 ( 464) 711 150.8 8.6e-36
XP_011510271 (OMIM: 114480,114550,211980,601763,60 ( 334) 709 150.3 8.7e-36
XP_016872252 (OMIM: 601761) PREDICTED: caspase-7 i ( 322) 606 129.9 1.1e-29
NP_203125 (OMIM: 601761) caspase-7 isoform alpha p ( 303) 583 125.4 2.4e-28
NP_001218 (OMIM: 601761) caspase-7 isoform alpha p ( 303) 583 125.4 2.4e-28
NP_001253985 (OMIM: 601761) caspase-7 isoform alph ( 303) 583 125.4 2.4e-28
NP_203124 (OMIM: 601761) caspase-7 isoform delta [ ( 336) 583 125.4 2.6e-28
XP_016872253 (OMIM: 601761) PREDICTED: caspase-7 i ( 311) 571 123.0 1.3e-27
NP_001307840 (OMIM: 601761) caspase-7 isoform g [H ( 311) 571 123.0 1.3e-27
XP_006718080 (OMIM: 601761) PREDICTED: caspase-7 i ( 317) 571 123.0 1.3e-27
XP_011538562 (OMIM: 601761) PREDICTED: caspase-7 i ( 270) 570 122.8 1.3e-27
NP_001253986 (OMIM: 601761) caspase-7 isoform e [H ( 388) 571 123.1 1.5e-27
NP_001253987 (OMIM: 601761) caspase-7 isoform f [H ( 278) 568 122.4 1.8e-27
NP_116786 (OMIM: 600636) caspase-3 preproprotein [ ( 277) 460 101.1 4.5e-21
XP_011530603 (OMIM: 600636) PREDICTED: caspase-3 i ( 277) 460 101.1 4.5e-21
NP_004337 (OMIM: 600636) caspase-3 preproprotein [ ( 277) 460 101.1 4.5e-21
NP_001217 (OMIM: 601532) caspase-6 isoform alpha p ( 293) 409 91.1 5e-18
NP_116787 (OMIM: 601532) caspase-6 isoform beta [H ( 204) 349 79.1 1.4e-14
NP_036246 (OMIM: 605848) caspase-14 precursor [Hom ( 242) 319 73.3 9.3e-13
NP_116764 (OMIM: 600639) caspase-2 isoform 1 prepr ( 452) 320 73.7 1.3e-12
NP_001215 (OMIM: 600639) caspase-2 isoform 2 [Homo ( 312) 306 70.8 6.7e-12
XP_005246952 (OMIM: 114480,114550,211980,601763,60 ( 279) 292 68.0 4.2e-11
XP_005246950 (OMIM: 114480,114550,211980,601763,60 ( 294) 292 68.0 4.4e-11
XP_006712856 (OMIM: 114480,114550,211980,601763,60 ( 235) 286 66.8 8.3e-11
NP_203522 (OMIM: 114480,114550,211980,601763,60727 ( 235) 286 66.8 8.3e-11
>>NP_116759 (OMIM: 601762,603909,605027,613659) caspase- (522 aa)
initn: 3432 init1: 3432 opt: 3432 Z-score: 3661.2 bits: 687.1 E(85289): 3.4e-197
Smith-Waterman score: 3432; 99.8% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSISIEADALNPE
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_116 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
430 440 450 460 470 480
490 500 510 520
pF1KE1 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
::::::::::::::::::::::::::::::::::::::::::
NP_116 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
490 500 510 520
>>XP_005246964 (OMIM: 601762,603909,605027,613659) PREDI (521 aa)
initn: 3446 init1: 1966 opt: 3413 Z-score: 3640.9 bits: 683.3 E(85289): 4.6e-196
Smith-Waterman score: 3413; 99.6% identity (99.8% similar) in 522 aa overlap (1-522:1-521)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_005 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALP-ESWQNKHAGSN
190 200 210 220 230
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE1 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSISIEADALNPE
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
XP_005 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE1 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
420 430 440 450 460 470
490 500 510 520
pF1KE1 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
::::::::::::::::::::::::::::::::::::::::::
XP_005 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
480 490 500 510 520
>>NP_116756 (OMIM: 601762,603909,605027,613659) caspase- (521 aa)
initn: 3111 init1: 3111 opt: 3116 Z-score: 3324.6 bits: 624.8 E(85289): 1.9e-178
Smith-Waterman score: 3116; 95.6% identity (97.6% similar) in 498 aa overlap (1-498:1-495)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSISIEADALNPE
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_116 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
:::::::::::::::::::::::::::::::::::::::::::::::::::: .:..:
NP_116 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPR---MLKFL
430 440 450 460 470
490 500 510 520
pF1KE1 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
. . .:. :.:.
NP_116 EKTMEIRGRKRTVWGAKQISATSLPTAISAQTPRPPMRRWSSVS
480 490 500 510 520
>>XP_006712859 (OMIM: 601762,603909,605027,613659) PREDI (272 aa)
initn: 1695 init1: 1695 opt: 1695 Z-score: 1815.0 bits: 344.5 E(85289): 2.4e-94
Smith-Waterman score: 1695; 99.6% identity (100.0% similar) in 251 aa overlap (272-522:22-272)
250 260 270 280 290 300
pF1KE1 NRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDRQ
::::::::::::::::::::::::::::::
XP_006 MLRHSWKPYRSPGKISMQVVMRAAVYRMNRNHRGLCVIVNNHSFTSLKDRQ
10 20 30 40 50
310 320 330 340 350 360
pF1KE1 GTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRF
60 70 80 90 100 110
370 380 390 400 410 420
pF1KE1 GAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSISIEADALNPEQ
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_006 GAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPEQ
120 130 140 150 160 170
430 440 450 460 470 480
pF1KE1 APTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILT
180 190 200 210 220 230
490 500 510 520
pF1KE1 AVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
:::::::::::::::::::::::::::::::::::::::::
XP_006 AVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
240 250 260 270
>>NP_001221 (OMIM: 601762,603909,605027,613659) caspase- (479 aa)
initn: 1695 init1: 1695 opt: 1695 Z-score: 1811.5 bits: 344.7 E(85289): 3.7e-94
Smith-Waterman score: 3058; 91.6% identity (91.8% similar) in 522 aa overlap (1-522:1-479)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALP------------
190 200 210 220
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
:::::::::::::::::::::::::::::
NP_001 -------------------------------RAAVYRMNRNHRGLCVIVNNHSFTSLKDR
230 240 250
310 320 330 340 350 360
pF1KE1 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE1 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSISIEADALNPE
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE1 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
380 390 400 410 420 430
490 500 510 520
pF1KE1 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
440 450 460 470
>>NP_116758 (OMIM: 601762,603909,605027,613659) caspase- (273 aa)
initn: 1547 init1: 1547 opt: 1547 Z-score: 1657.3 bits: 315.4 E(85289): 1.4e-85
Smith-Waterman score: 1547; 100.0% identity (100.0% similar) in 240 aa overlap (1-240:1-240)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
NP_116 EGSCVQDESEPQRPLCHCQQPQLYLPEGQTRNP
250 260 270
>>NP_001193453 (OMIM: 601762,603909,605027,613659) caspa (455 aa)
initn: 2983 init1: 1547 opt: 1547 Z-score: 1654.2 bits: 315.5 E(85289): 2.1e-85
Smith-Waterman score: 2853; 87.0% identity (87.2% similar) in 522 aa overlap (1-522:1-455)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
NP_001 ------------------------------------------------------------
310 320 330 340 350 360
pF1KE1 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------EILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
250 260 270 280 290
370 380 390 400 410 420
pF1KE1 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSISIEADALNPE
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE1 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
360 370 380 390 400 410
490 500 510 520
pF1KE1 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
420 430 440 450
>>XP_011510292 (OMIM: 601762,603909,605027,613659) PREDI (272 aa)
initn: 1494 init1: 1461 opt: 1528 Z-score: 1637.1 bits: 311.6 E(85289): 1.9e-84
Smith-Waterman score: 1528; 99.6% identity (99.6% similar) in 240 aa overlap (1-240:1-239)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALP-ESWQNKHAGSN
190 200 210 220 230
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
XP_011 EGSCVQDESEPQRPLCHCQQPQLYLPEGQTRNP
240 250 260 270
>>NP_001293012 (OMIM: 601762,603909,605027,613659) caspa (247 aa)
initn: 1469 init1: 1469 opt: 1469 Z-score: 1574.8 bits: 299.9 E(85289): 5.6e-81
Smith-Waterman score: 1469; 95.5% identity (97.1% similar) in 242 aa overlap (1-242:1-242)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
::::::::::::::::::::::::::::::::::::::::::::::::. . . :.
NP_001 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPEGVFVFLNEGDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
::
NP_001 GNSPDDL
>>NP_001193471 (OMIM: 601762,603909,605027,613659) caspa (478 aa)
initn: 1493 init1: 1460 opt: 1460 Z-score: 1561.2 bits: 298.4 E(85289): 3.2e-80
Smith-Waterman score: 2742; 86.9% identity (89.0% similar) in 498 aa overlap (1-498:1-452)
10 20 30 40 50 60
pF1KE1 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFEHLLAEDLLSEEDPFFLAELLYIIRQKKLLQHLNCTKEEVERLLPTRQRVSLFRNLLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSEGIDSENLKDMIFLLKDSLPKTEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALPQESWQNKHAGSN
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLEALP------------
190 200 210 220
250 260 270 280 290 300
pF1KE1 GNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMNRNHRGLCVIVNNHSFTSLKDR
:::::::::::::::::::::::::::::
NP_001 -------------------------------RAAVYRMNRNHRGLCVIVNNHSFTSLKDR
230 240 250
310 320 330 340 350 360
pF1KE1 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGR
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE1 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSISIEADALNPE
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 FGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPE
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE1 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSIL
:::::::::::::::::::::::::::::::::::::::::::::::::::: .:..:
NP_001 QAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPR---MLKFL
380 390 400 410 420 430
490 500 510 520
pF1KE1 TAVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
. . .:. :.:.
NP_001 EKTMEIRGRKRTVWGAKQISATSLPTAISAQTPRPPMRRWSSVS
440 450 460 470
522 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:09:09 2016 done: Sun Nov 6 18:09:11 2016
Total Scan time: 9.370 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]