Result of FASTA (omim) for
pFN21AE1895
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1895, 417 aa
1>>>pF1KE1895 417 - 417 aa - 417 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3531+/-0.00033; mu= 10.4177+/- 0.021
mean_var=194.9603+/-38.366, 0's: 0 Z-trim(122.0): 91 B-trim: 175 in 1/56
Lambda= 0.091855
statistics sampled from 39442 (39543) to 39442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.464), width: 16
Scan time: 9.890
The best scores are: opt bits E(85289)
NP_003781 (OMIM: 603366) tumor necrosis factor rec ( 417) 3046 415.7 1e-115
NP_683868 (OMIM: 603366) tumor necrosis factor rec ( 372) 2314 318.7 1.5e-86
NP_683867 (OMIM: 603366) tumor necrosis factor rec ( 380) 1531 214.9 2.7e-55
NP_683866 (OMIM: 603366) tumor necrosis factor rec ( 426) 1512 212.5 1.7e-54
NP_001034753 (OMIM: 603366) tumor necrosis factor ( 181) 1389 195.8 7.5e-50
NP_683871 (OMIM: 603366) tumor necrosis factor rec ( 234) 1260 178.8 1.3e-44
NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 277 48.6 2.3e-05
NP_001333020 (OMIM: 142680,191190,614810) tumor ne ( 347) 268 47.5 6.1e-05
NP_001056 (OMIM: 142680,191190,614810) tumor necro ( 455) 268 47.6 7.3e-05
NP_001333021 (OMIM: 142680,191190,614810) tumor ne ( 302) 264 46.9 8e-05
NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 258 45.9 0.0001
XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 258 45.9 0.0001
XP_011524546 (OMIM: 174810,602080,603499,612301) P ( 621) 255 46.1 0.0003
NP_001307548 (OMIM: 134637,601859) tumor necrosis ( 197) 237 43.1 0.00072
NP_690611 (OMIM: 134637,601859) tumor necrosis fac ( 220) 237 43.2 0.00078
NP_690610 (OMIM: 134637,601859) tumor necrosis fac ( 314) 237 43.4 0.00099
NP_000034 (OMIM: 134637,601859) tumor necrosis fac ( 335) 237 43.4 0.001
XP_011538069 (OMIM: 134637,601859) PREDICTED: tumo ( 350) 237 43.4 0.0011
XP_006717882 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 237 43.4 0.0011
XP_011538068 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 237 43.4 0.0011
XP_011538067 (OMIM: 134637,601859) PREDICTED: tumo ( 368) 237 43.4 0.0011
XP_011538066 (OMIM: 134637,601859) PREDICTED: tumo ( 389) 237 43.5 0.0011
NP_001257878 (OMIM: 174810,602080,603499,612301) t ( 263) 214 40.2 0.0072
NP_001257880 (OMIM: 174810,602080,603499,612301) t ( 299) 214 40.3 0.0079
NP_001257879 (OMIM: 174810,602080,603499,612301) t ( 337) 214 40.3 0.0086
XP_016875721 (OMIM: 186711,615122) PREDICTED: CD27 ( 405) 214 40.4 0.0097
>>NP_003781 (OMIM: 603366) tumor necrosis factor recepto (417 aa)
initn: 3046 init1: 3046 opt: 3046 Z-score: 2198.3 bits: 415.7 E(85289): 1e-115
Smith-Waterman score: 3046; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KE1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
370 380 390 400 410
>>NP_683868 (OMIM: 603366) tumor necrosis factor recepto (372 aa)
initn: 2674 init1: 2301 opt: 2314 Z-score: 1674.6 bits: 318.7 E(85289): 1.5e-86
Smith-Waterman score: 2588; 89.2% identity (89.2% similar) in 417 aa overlap (1-417:1-372)
10 20 30 40 50 60
pF1KE1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA-------
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
::::::::::::::::::::::
NP_683 --------------------------------------ASQVALENCSAVADTRCGCKPG
60 70
130 140 150 160 170 180
pF1KE1 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE1 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE1 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE1 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
260 270 280 290 300 310
370 380 390 400 410
pF1KE1 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
320 330 340 350 360 370
>>NP_683867 (OMIM: 603366) tumor necrosis factor recepto (380 aa)
initn: 2766 init1: 1531 opt: 1531 Z-score: 1113.7 bits: 214.9 E(85289): 2.7e-55
Smith-Waterman score: 2696; 90.9% identity (91.1% similar) in 417 aa overlap (1-417:1-380)
10 20 30 40 50 60
pF1KE1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
::::::::::::::::::: .:::
NP_683 TSTLGSCPERCAAVCGWRQ-------------------------------------NEAG
190 200
250 260 270 280 290 300
pF1KE1 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
270 280 290 300 310 320
370 380 390 400 410
pF1KE1 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
330 340 350 360 370 380
>>NP_683866 (OMIM: 603366) tumor necrosis factor recepto (426 aa)
initn: 2884 init1: 1509 opt: 1512 Z-score: 1099.5 bits: 212.5 E(85289): 1.7e-54
Smith-Waterman score: 2873; 94.6% identity (96.0% similar) in 426 aa overlap (1-417:1-426)
10 20 30 40 50 60
pF1KE1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
130 140 150 160 170 180
190 200 210 220 230
pF1KE1 TS--TLGSCPERCA------AVCGWR-QMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK
: .:.. : . .: : : .:::::::::::::::::::::::::::::::
NP_683 TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE1 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS
370 380 390 400 410 420
pF1KE1 RLQRGP
::::::
NP_683 RLQRGP
>>NP_001034753 (OMIM: 603366) tumor necrosis factor rece (181 aa)
initn: 1389 init1: 1389 opt: 1389 Z-score: 1015.9 bits: 195.8 E(85289): 7.5e-50
Smith-Waterman score: 1389; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181)
10 20 30 40 50 60
pF1KE1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
:
NP_001 T
>>NP_683871 (OMIM: 603366) tumor necrosis factor recepto (234 aa)
initn: 1260 init1: 1260 opt: 1260 Z-score: 922.2 bits: 178.8 E(85289): 1.3e-44
Smith-Waterman score: 1266; 56.1% identity (56.1% similar) in 417 aa overlap (1-417:1-234)
10 20 30 40 50 60
pF1KE1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA-------
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
NP_683 ------------------------------------------------------------
130 140 150 160 170 180
pF1KE1 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
NP_683 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE1 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
::::
NP_683 --------------------------------------------------------DEAG
250 260 270 280 290 300
pF1KE1 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
60 70 80 90 100 110
310 320 330 340 350 360
pF1KE1 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
120 130 140 150 160 170
370 380 390 400 410
pF1KE1 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
180 190 200 210 220 230
>>NP_003811 (OMIM: 602746) tumor necrosis factor recepto (283 aa)
initn: 162 init1: 112 opt: 277 Z-score: 217.2 bits: 48.6 E(85289): 2.3e-05
Smith-Waterman score: 279; 28.4% identity (49.1% similar) in 218 aa overlap (15-220:25-219)
10 20 30 40 50
pF1KE1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRG
: :..::: . . : : . . .: ::
NP_003 MEPPGDWGPPPWRSTPKTDVLRLVLYLTFLGAPCYAPAL-PSCK---EDEYPVGSECCPK
10 20 30 40 50
60 70 80 90 100
pF1KE1 CPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHN--SECARCQACDEQASQVALENCS
: :. .: : : : ..: :: :..: : : :.: .:: :: . : .:::
NP_003 CSPGYRVKEACGELTG-TVCEPCPPGTYIA---HLNGLSKCLQCQMCDPAMGLRASRNCS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPC---LDCGALHRHTRLLCSRRDTDCGTC
. .. :::.:: : :. .. .: : . .: . .:: : .:
NP_003 RTENAVCGCSPGHF-------CIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNC
120 130 140 150 160
170 180 190 200 210
pF1KE1 LPGFYEHGDGCVSCPTSTLGSCPE--RCA-----AVCGWRQMFWVQVLLAGLVVPLLLGA
:: . :..:: : . .:. : : . :: .:.: .: ... .
NP_003 PPGTFS--------PNGTLEECQHQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCS
170 180 190 200 210
220 230 240 250 260 270
pF1KE1 TLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVG
:.
NP_003 TVGLIICVKRRKPRGDVVKVIVSVQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFT
220 230 240 250 260 270
>>NP_001333020 (OMIM: 142680,191190,614810) tumor necros (347 aa)
initn: 331 init1: 132 opt: 268 Z-score: 209.7 bits: 47.5 E(85289): 6.1e-05
Smith-Waterman score: 382; 28.7% identity (51.1% similar) in 348 aa overlap (101-417:3-336)
80 90 100 110 120
pF1KE1 LVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVEC---QV
:: . .:.. :: :::. . . . ..
NP_001 MGQVEISSCTVDRDTVCGCRKNQYRHYWSENL
10 20 30
130 140 150 160 170 180
pF1KE1 SQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLG-S
:: : :. ::. :..: : :..... :: ::. . . :::: . .
NP_001 FQC-----FNCSLCLN-GTVH----LSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLE
40 50 60 70 80
190 200 210 220
pF1KE1 CPERC----AAVCGWRQ----MFWVQVLLAGLVVPLLLGATLTYTYRH---------CWP
: . : : : .. .. :.. :: . :: : : :.. :
NP_001 CTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGK
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE1 HKPLVTADEAGM--EALTPPPATHLSPLDSAHTLLAP-PDSSEKICTVQLVGNSWTPGYP
: .. : . :.: :. .: . ..: :.:. .. :. :..
NP_001 STPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDC--PNFA
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE1 ETQEALCPQVTWSWDQLPSRALG--PAAAPTLSPESPAGSPAMMLQPGPQ-LYDVMDAVP
.. . : . : . . ::. : : . :. : .: . : :: :.. ::
NP_001 APRREVAPPYQGA-DPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVP
210 220 230 240 250
350 360 370 380 390
pF1KE1 ARRWKEFVRTLGLREAEIEAVEVEIGR-FRDQQYEMLKRWRQQQP---AGLGAVYAALER
::::::: ::: . ::. .:.. :: .:. :: :: ::.. : : : . .:.
NP_001 PLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRD
260 270 280 290 300 310
400 410
pF1KE1 MGLDGCVEDLRSRLQRGP
: : ::.::.. : ::
NP_001 MDLLGCLEDIEEALC-GPAALPPAPSLLR
320 330 340
>>NP_001056 (OMIM: 142680,191190,614810) tumor necrosis (455 aa)
initn: 407 init1: 132 opt: 268 Z-score: 208.2 bits: 47.6 E(85289): 7.3e-05
Smith-Waterman score: 532; 28.9% identity (50.8% similar) in 429 aa overlap (20-417:34-444)
10 20 30 40
pF1KE1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCR
:: : . :. : . .: . . .::
NP_001 STVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREK---RDSVCPQGKYIHPQNNSICCT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 GCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSA
: : :: : : .. : : . .: : ::: .: :. : .. .:: . .:..
NP_001 KCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-HCLSCSKCRKEMGQVEISSCTV
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 VADTRCGCKPGWFVEC---QVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL
:: :::. . . . .. :: : :. ::. :..: : :..... ::
NP_001 DRDTVCGCRKNQYRHYWSENLFQC-----FNCSLCLN-GTVH----LSCQEKQNTVCTCH
120 130 140 150 160
170 180 190 200 210
pF1KE1 PGFYEHGDGCVSCPTSTLG-SCPERC----AAVCGWRQ----MFWVQVLLAGLVVPLLLG
::. . . :::: . . : . : : : .. .. :.. :: . ::
NP_001 AGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLF
170 180 190 200 210 220
220 230 240 250 260
pF1KE1 ATLTYTYRH---------CWPHKPLVTADEAGM--EALTPPPATHLSPLDSAHTLLAP-P
: : :.. : : .. : . :.: :. .: . ..: :
NP_001 IGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVP
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE1 DSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALG--PAAAPTLSPESPAG
.:. .. :. :.. .. . : . : . . ::. : : . :. :
NP_001 SSTFTSSSTYTPGDC--PNFAAPRREVAPPYQGA-DPILATALASDPIPNPLQKWEDSAH
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE1 SPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGR-FRDQQYEMLKR
.: . : :: :.. :: ::::::: ::: . ::. .:.. :: .:. :: ::
NP_001 KPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLAT
350 360 370 380 390 400
390 400 410
pF1KE1 WRQQQP---AGLGAVYAALERMGLDGCVEDLRSRLQRGP
::.. : : : . .:. : : ::.::.. : ::
NP_001 WRRRTPRREATLELLGRVLRDMDLLGCLEDIEEALC-GPAALPPAPSLLR
410 420 430 440 450
>>NP_001333021 (OMIM: 142680,191190,614810) tumor necros (302 aa)
initn: 225 init1: 132 opt: 264 Z-score: 207.5 bits: 46.9 E(85289): 8e-05
Smith-Waterman score: 278; 28.6% identity (49.0% similar) in 294 aa overlap (158-417:4-291)
130 140 150 160 170 180
pF1KE1 SQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSC
:: :: ... . : : :.: ::
NP_001 MQWRDLGSLQPLPPRFKQFS-CFSLPSSWDYSC
10 20 30
190 200 210 220
pF1KE1 PE--RCAAVCGWRQMFWVQ-------------VLLAGLVVPLLLGATLTYTYRH------
. .:. .: :. :. :.. :: . :: : : :..
NP_001 KKSLECTKLC-LPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLY
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE1 ---CWPHKPLVTADEAGM--EALTPPPATHLSPLDSAHTLLAP-PDSSEKICTVQLVGNS
: : .. : . :.: :. .: . ..: :.:. .. :.
NP_001 SIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDC
100 110 120 130 140 150
290 300 310 320 330
pF1KE1 WTPGYPETQEALCPQVTWSWDQLPSRALG--PAAAPTLSPESPAGSPAMMLQPGPQ-LYD
:.. .. . : . : . . ::. : : . :. : .: . : ::
NP_001 --PNFAAPRREVAPPYQGA-DPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLYA
160 170 180 190 200
340 350 360 370 380 390
pF1KE1 VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGR-FRDQQYEMLKRWRQQQP---AGLGAV
:.. :: ::::::: ::: . ::. .:.. :: .:. :: :: ::.. : : : .
NP_001 VVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELL
210 220 230 240 250 260
400 410
pF1KE1 YAALERMGLDGCVEDLRSRLQRGP
.:. : : ::.::.. : ::
NP_001 GRVLRDMDLLGCLEDIEEALC-GPAALPPAPSLLR
270 280 290 300
417 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:32:59 2016 done: Sun Nov 6 19:33:01 2016
Total Scan time: 9.890 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]