Result of FASTA (omim) for
pFN21AE2530
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2530, 3122 aa
1>>>pF1KE2530 3122 - 3122 aa - 3122 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.3064+/-0.000672; mu= 3.4374+/- 0.041
mean_var=449.4603+/-91.155, 0's: 0 Z-trim(115.1): 265 B-trim: 0 in 0/53
Lambda= 0.060496
statistics sampled from 26089 (26350) to 26089 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.287), width: 16
Scan time: 13.940
The best scores are: opt bits E(91774)
NP_000417 (OMIM: 156225,607855,618138) laminin sub (3122) 21710 1913.1 0
NP_001073291 (OMIM: 156225,607855,618138) laminin (3118) 21664 1909.1 0
XP_016866341 (OMIM: 156225,607855,618138) laminin (2587) 14830 1312.5 0
XP_005267038 (OMIM: 156225,607855,618138) laminin (3210) 14830 1312.7 0
XP_016866340 (OMIM: 156225,607855,618138) laminin (3212) 14830 1312.7 0
XP_011534122 (OMIM: 156225,607855,618138) laminin (3208) 14805 1310.5 0
XP_005267039 (OMIM: 156225,607855,618138) laminin (3206) 14789 1309.1 0
XP_016866342 (OMIM: 156225,607855,618138) laminin (1916) 7333 658.1 4.4e-187
NP_005550 (OMIM: 150320,615960) laminin subunit al (3075) 7179 644.9 6.6e-183
XP_011524284 (OMIM: 226650,226700,245660,600805) l (3243) 1426 142.8 9.6e-32
NP_001121189 (OMIM: 226650,226700,245660,600805) l (3277) 1426 142.8 9.7e-32
NP_937762 (OMIM: 226650,226700,245660,600805) lami (3333) 1426 142.8 9.8e-32
XP_011524282 (OMIM: 226650,226700,245660,600805) l (3336) 1426 142.8 9.8e-32
XP_011524281 (OMIM: 226650,226700,245660,600805) l (3339) 1426 142.8 9.8e-32
XP_011524280 (OMIM: 226650,226700,245660,600805) l (3342) 1426 142.8 9.8e-32
XP_011524283 (OMIM: 226650,226700,245660,600805) l (3298) 1398 140.4 5.3e-31
NP_001289925 (OMIM: 226650,226700,245660,600805) l ( 488) 1356 135.7 2e-30
XP_006723861 (OMIM: 601033) laminin subunit alpha- (2300) 1329 134.1 2.8e-29
NP_005551 (OMIM: 601033) laminin subunit alpha-5 p (3695) 1329 134.4 3.7e-29
XP_006723859 (OMIM: 601033) laminin subunit alpha- (3700) 1329 134.4 3.7e-29
XP_011527121 (OMIM: 601033) laminin subunit alpha- (3609) 1322 133.8 5.6e-29
XP_011527120 (OMIM: 601033) laminin subunit alpha- (3654) 1322 133.8 5.6e-29
NP_002284 (OMIM: 150290) laminin subunit gamma-1 p (1609) 1309 132.2 7.4e-29
XP_016881232 (OMIM: 226650,226700,245660,600805) l (2626) 1162 119.6 7.3e-25
NP_002282 (OMIM: 150240,615191) laminin subunit be (1786) 1056 110.2 3.5e-22
XP_016867690 (OMIM: 150240,615191) laminin subunit (1810) 1056 110.2 3.5e-22
XP_016867691 (OMIM: 150240,615191) laminin subunit (1212) 1007 105.7 5.3e-21
NP_001278789 (OMIM: 142461,224410,255800) basement (4392) 952 101.6 3.3e-19
XP_016856610 (OMIM: 142461,224410,255800) basement (4439) 952 101.6 3.3e-19
XP_016856609 (OMIM: 142461,224410,255800) basement (4456) 952 101.6 3.3e-19
XP_011539620 (OMIM: 142461,224410,255800) basement (4574) 952 101.6 3.4e-19
NP_005520 (OMIM: 142461,224410,255800) basement me (4391) 951 101.5 3.5e-19
XP_016856611 (OMIM: 142461,224410,255800) basement (4438) 951 101.5 3.5e-19
XP_005265184 (OMIM: 150325,609049,614199) laminin (1798) 927 98.9 8.6e-19
NP_002283 (OMIM: 150325,609049,614199) laminin sub (1798) 927 98.9 8.6e-19
XP_011514282 (OMIM: 616380) laminin subunit beta-4 (1564) 800 87.8 1.7e-15
XP_016867369 (OMIM: 616380) laminin subunit beta-4 (1567) 800 87.8 1.7e-15
XP_011514281 (OMIM: 616380) laminin subunit beta-4 (1703) 800 87.8 1.8e-15
XP_011514280 (OMIM: 616380) laminin subunit beta-4 (1723) 800 87.8 1.8e-15
XP_016867368 (OMIM: 616380) laminin subunit beta-4 (1753) 800 87.8 1.8e-15
NP_031382 (OMIM: 616380) laminin subunit beta-4 is (1761) 800 87.8 1.8e-15
NP_001304975 (OMIM: 616380) laminin subunit beta-4 (1761) 800 87.8 1.8e-15
XP_011514277 (OMIM: 616380) laminin subunit beta-4 (1772) 800 87.8 1.9e-15
NP_001304976 (OMIM: 616380) laminin subunit beta-4 (1101) 760 84.1 1.5e-14
XP_016881233 (OMIM: 226650,226700,245660,600805) l (1856) 755 83.9 2.9e-14
NP_001304977 (OMIM: 616380) laminin subunit beta-4 ( 772) 713 79.8 2.1e-13
NP_000218 (OMIM: 226650,226700,245660,600805) lami (1724) 644 74.2 2.3e-11
XP_016866343 (OMIM: 600133,615235) laminin subunit (1816) 636 73.5 3.8e-11
NP_001098677 (OMIM: 600133,615235) laminin subunit (1816) 636 73.5 3.8e-11
NP_002281 (OMIM: 600133,615235) laminin subunit al (1816) 636 73.5 3.8e-11
>>NP_000417 (OMIM: 156225,607855,618138) laminin subunit (3122 aa)
initn: 21710 init1: 21710 opt: 21710 Z-score: 10259.3 bits: 1913.1 E(91774): 0
Smith-Waterman score: 21710; 100.0% identity (100.0% similar) in 3122 aa overlap (1-3122:1-3122)
10 20 30 40 50 60
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE2 IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE2 SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE2 DLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE2 CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE2 TGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KE2 ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KE2 SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KE2 IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KE2 GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KE2 VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
2890 2900 2910 2920 2930 2940
2950 2960 2970 2980 2990 3000
pF1KE2 GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
2950 2960 2970 2980 2990 3000
3010 3020 3030 3040 3050 3060
pF1KE2 VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
3010 3020 3030 3040 3050 3060
3070 3080 3090 3100 3110 3120
pF1KE2 NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
3070 3080 3090 3100 3110 3120
pF1KE2 AN
::
NP_000 AN
>>NP_001073291 (OMIM: 156225,607855,618138) laminin subu (3118 aa)
initn: 21668 init1: 17394 opt: 21664 Z-score: 10237.6 bits: 1909.1 E(91774): 0
Smith-Waterman score: 21664; 99.8% identity (99.9% similar) in 3122 aa overlap (1-3122:1-3118)
10 20 30 40 50 60
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE2 IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE2 SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE2 DLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
NP_001 DLKADDKIYFGGLPTLRNL----RPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
2470 2480 2490 2500 2510
2530 2540 2550 2560 2570 2580
pF1KE2 CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
2520 2530 2540 2550 2560 2570
2590 2600 2610 2620 2630 2640
pF1KE2 TGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
2580 2590 2600 2610 2620 2630
2650 2660 2670 2680 2690 2700
pF1KE2 ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
2640 2650 2660 2670 2680 2690
2710 2720 2730 2740 2750 2760
pF1KE2 SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
2700 2710 2720 2730 2740 2750
2770 2780 2790 2800 2810 2820
pF1KE2 IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
2760 2770 2780 2790 2800 2810
2830 2840 2850 2860 2870 2880
pF1KE2 GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
2820 2830 2840 2850 2860 2870
2890 2900 2910 2920 2930 2940
pF1KE2 VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
2880 2890 2900 2910 2920 2930
2950 2960 2970 2980 2990 3000
pF1KE2 GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
2940 2950 2960 2970 2980 2990
3010 3020 3030 3040 3050 3060
pF1KE2 VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
3000 3010 3020 3030 3040 3050
3070 3080 3090 3100 3110 3120
pF1KE2 NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
3060 3070 3080 3090 3100 3110
pF1KE2 AN
::
NP_001 AN
>>XP_016866341 (OMIM: 156225,607855,618138) laminin subu (2587 aa)
initn: 14750 init1: 14750 opt: 14830 Z-score: 7015.0 bits: 1312.5 E(91774): 0
Smith-Waterman score: 17005; 96.6% identity (96.6% similar) in 2587 aa overlap (624-3122:1-2587)
600 610 620 630 640 650
pF1KE2 KLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVL
::::::::::::::::::::::::::::::
XP_016 MIILEGNDLSISTAQDEVYLHPSEEHTNVL
10 20 30
660 670 680 690 700 710
pF1KE2 LLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPT
40 50 60 70 80 90
720 730 740 750 760 770
pF1KE2 DGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGEC
100 110 120 130 140 150
780 790 800 810 820 830
pF1KE2 LNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICD
160 170 180 190 200 210
840 850 860 870 880 890
pF1KE2 GCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGT
220 230 240 250 260 270
900 910 920 930 940 950
pF1KE2 TGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKP
280 290 300 310 320 330
pF1KE2 ------------------------------------------------------------
XP_016 NMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCVCKSGFVGKQCNLGRQVHQQEEQPRRAQ
340 350 360 370 380 390
960 970 980
pF1KE2 ---------------------------AGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC
:::::::::::::::::::::::::::::::::
XP_016 RVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC
400 410 420 430 440 450
990 1000 1010 1020 1030 1040
pF1KE2 WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCA
460 470 480 490 500 510
1050 1060 1070 1080 1090 1100
pF1KE2 PNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNL
520 530 540 550 560 570
1110 1120 1130 1140 1150 1160
pF1KE2 CDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSS
580 590 600 610 620 630
1170 1180 1190 1200 1210 1220
pF1KE2 CYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMR
640 650 660 670 680 690
1230 1240 1250 1260 1270 1280
pF1KE2 EDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHAR
700 710 720 730 740 750
1290 1300 1310 1320 1330 1340
pF1KE2 IIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATY
760 770 780 790 800 810
1350 1360 1370 1380 1390 1400
pF1KE2 GNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQP
820 830 840 850 860 870
1410 1420 1430 1440 1450 1460
pF1KE2 GGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPND
880 890 900 910 920 930
1470 1480 1490 1500 1510 1520
pF1KE2 CQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ
940 950 960 970 980 990
1530 1540 1550 1560 1570 1580
pF1KE2 ECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGD
1000 1010 1020 1030 1040 1050
1590 1600 1610 1620 1630 1640
pF1KE2 LARLEQMVMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LARLEQMVMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVT
1060 1070 1080 1090 1100 1110
1650 1660 1670 1680 1690 1700
pF1KE2 EMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGT
1120 1130 1140 1150 1160 1170
1710 1720 1730 1740 1750 1760
pF1KE2 RDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGEN
1180 1190 1200 1210 1220 1230
1770 1780 1790 1800 1810 1820
pF1KE2 EEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGK
1240 1250 1260 1270 1280 1290
1830 1840 1850 1860 1870 1880
pF1KE2 RQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRK
1300 1310 1320 1330 1340 1350
1890 1900 1910 1920 1930 1940
pF1KE2 LAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEA
1360 1370 1380 1390 1400 1410
1950 1960 1970 1980 1990 2000
pF1KE2 KDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENA
1420 1430 1440 1450 1460 1470
2010 2020 2030 2040 2050 2060
pF1KE2 DARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGL
1480 1490 1500 1510 1520 1530
2070 2080 2090 2100 2110 2120
pF1KE2 KKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKK
1540 1550 1560 1570 1580 1590
2130 2140 2150 2160 2170 2180
pF1KE2 NISEIKELINQARKQANSIKVSVSSGGDCIRTYKPEIKKGSYNNIVVNVKTAVADNLLFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NISEIKELINQARKQANSIKVSVSSGGDCIRTYKPEIKKGSYNNIVVNVKTAVADNLLFY
1600 1610 1620 1630 1640 1650
2190 2200 2210 2220 2230 2240
pF1KE2 LGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISV
1660 1670 1680 1690 1700 1710
2250 2260 2270 2280 2290 2300
pF1KE2 RALDGPKASIVPSTHHSTSPPGYTILDVDANAMLFVGGLTGKLKKADAVRVITFTGCMGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALDGPKASIVPSTHHSTSPPGYTILDVDANAMLFVGGLTGKLKKADAVRVITFTGCMGE
1720 1730 1740 1750 1760 1770
2310 2320 2330 2340 2350 2360
pF1KE2 TYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFDGEGYALVSRPIRWYPNISTVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFDGEGYALVSRPIRWYPNISTVM
1780 1790 1800 1810 1820 1830
2370 2380 2390 2400 2410 2420
pF1KE2 FKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSF
1840 1850 1860 1870 1880 1890
2430 2440 2450 2460 2470 2480
pF1KE2 TLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARP
1900 1910 1920 1930 1940 1950
2490 2500 2510 2520 2530 2540
pF1KE2 EVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSFPKPGFVELSPVPID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSFPKPGFVELSPVPID
1960 1970 1980 1990 2000 2010
2550 2560 2570 2580 2590 2600
pF1KE2 VGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGART
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 VGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVHLSTGART
2020 2030 2040 2050 2060 2070
2610 2620 2630 2640 2650 2660
pF1KE2 MRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVKKLFVGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVKKLFVGGA
2080 2090 2100 2110 2120 2130
2670 2680 2690 2700 2710 2720
pF1KE2 PPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKLREDEDGAAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKLREDEDGAAPA
2140 2150 2160 2170 2180 2190
2730 2740 2750 2760 2770 2780
pF1KE2 EIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKN
2200 2210 2220 2230 2240 2250
2790 2800 2810 2820 2830 2840
pF1KE2 RLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDG
2260 2270 2280 2290 2300 2310
2850 2860 2870 2880 2890 2900
pF1KE2 QWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYS
2320 2330 2340 2350 2360 2370
2910 2920 2930 2940 2950 2960
pF1KE2 IDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQRGTYFDGTGFAKAVGGFKVGLDLLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQRGTYFDGTGFAKAVGGFKVGLDLLVE
2380 2390 2400 2410 2420 2430
2970 2980 2990 3000 3010 3020
pF1KE2 FEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQW
2440 2450 2460 2470 2480 2490
3030 3040 3050 3060 3070 3080
pF1KE2 HKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFR
2500 2510 2520 2530 2540 2550
3090 3100 3110 3120
pF1KE2 GCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCPAN
:::::::::::::::::::::::::::::::::::::
XP_016 GCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCPAN
2560 2570 2580
>>XP_005267038 (OMIM: 156225,607855,618138) laminin subu (3210 aa)
initn: 14750 init1: 14750 opt: 14830 Z-score: 7014.0 bits: 1312.7 E(91774): 0
Smith-Waterman score: 21163; 97.2% identity (97.2% similar) in 3154 aa overlap (57-3122:57-3210)
30 40 50 60 70 80
pF1KE2 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
::::::::::::::::::::::::::::::
XP_005 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE2 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE2 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE2 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE2 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE2 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
330 340 350 360 370 380
390 400 410 420 430 440
pF1KE2 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
390 400 410 420 430 440
450 460 470 480 490 500
pF1KE2 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
450 460 470 480 490 500
510 520 530 540 550 560
pF1KE2 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
510 520 530 540 550 560
570 580 590 600 610 620
pF1KE2 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
570 580 590 600 610 620
630 640 650 660 670 680
pF1KE2 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
630 640 650 660 670 680
690 700 710 720 730 740
pF1KE2 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
690 700 710 720 730 740
750 760 770 780 790 800
pF1KE2 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
750 760 770 780 790 800
810 820 830 840 850 860
pF1KE2 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
810 820 830 840 850 860
870 880 890 900 910 920
pF1KE2 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
870 880 890 900 910 920
930 940 950
pF1KE2 SEVCHSQTGQCECRANVQGQRCDKCK----------------------------------
::::::::::::::::::::::::::
XP_005 SEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCV
930 940 950 960 970 980
pF1KE2 ------------------------------------------------------AGTFGL
::::::
XP_005 CKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGL
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KE2 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KE2 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KE2 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KE2 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KE2 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KE2 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KE2 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KE2 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KE2 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KE2 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KE2 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KE2 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KE2 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KE2 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KE2 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KE2 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KE2 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KE2 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KE2 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KE2 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
2610 2620 2630 2640 2650 2660
2580 2590 2600 2610 2620 2630
pF1KE2 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
2670 2680 2690 2700 2710 2720
2640 2650 2660 2670 2680 2690
pF1KE2 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
2730 2740 2750 2760 2770 2780
2700 2710 2720 2730 2740 2750
pF1KE2 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
2790 2800 2810 2820 2830 2840
2760 2770 2780 2790 2800 2810
pF1KE2 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
2850 2860 2870 2880 2890 2900
2820 2830 2840 2850 2860 2870
pF1KE2 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
2910 2920 2930 2940 2950 2960
2880 2890 2900 2910 2920 2930
pF1KE2 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
2970 2980 2990 3000 3010 3020
2940 2950 2960 2970 2980 2990
pF1KE2 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
3030 3040 3050 3060 3070 3080
3000 3010 3020 3030 3040 3050
pF1KE2 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
3090 3100 3110 3120 3130 3140
3060 3070 3080 3090 3100 3110
pF1KE2 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
3150 3160 3170 3180 3190 3200
3120
pF1KE2 CPAN
::::
XP_005 CPAN
3210
>>XP_016866340 (OMIM: 156225,607855,618138) laminin subu (3212 aa)
initn: 14750 init1: 14750 opt: 14830 Z-score: 7014.0 bits: 1312.7 E(91774): 0
Smith-Waterman score: 21163; 97.2% identity (97.2% similar) in 3154 aa overlap (57-3122:59-3212)
30 40 50 60 70 80
pF1KE2 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
::::::::::::::::::::::::::::::
XP_016 AVRLAHELRARGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE2 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE2 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE2 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE2 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE2 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
330 340 350 360 370 380
390 400 410 420 430 440
pF1KE2 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
390 400 410 420 430 440
450 460 470 480 490 500
pF1KE2 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
450 460 470 480 490 500
510 520 530 540 550 560
pF1KE2 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
510 520 530 540 550 560
570 580 590 600 610 620
pF1KE2 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
570 580 590 600 610 620
630 640 650 660 670 680
pF1KE2 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
630 640 650 660 670 680
690 700 710 720 730 740
pF1KE2 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
690 700 710 720 730 740
750 760 770 780 790 800
pF1KE2 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
750 760 770 780 790 800
810 820 830 840 850 860
pF1KE2 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
810 820 830 840 850 860
870 880 890 900 910 920
pF1KE2 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
870 880 890 900 910 920
930 940 950
pF1KE2 SEVCHSQTGQCECRANVQGQRCDKCK----------------------------------
::::::::::::::::::::::::::
XP_016 SEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCV
930 940 950 960 970 980
pF1KE2 ------------------------------------------------------AGTFGL
::::::
XP_016 CKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGL
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KE2 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KE2 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KE2 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KE2 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KE2 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KE2 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KE2 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KE2 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KE2 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KE2 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KE2 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KE2 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KE2 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KE2 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KE2 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KE2 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KE2 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KE2 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KE2 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KE2 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
2610 2620 2630 2640 2650 2660
2580 2590 2600 2610 2620 2630
pF1KE2 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
2670 2680 2690 2700 2710 2720
2640 2650 2660 2670 2680 2690
pF1KE2 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
2730 2740 2750 2760 2770 2780
2700 2710 2720 2730 2740 2750
pF1KE2 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
2790 2800 2810 2820 2830 2840
2760 2770 2780 2790 2800 2810
pF1KE2 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
2850 2860 2870 2880 2890 2900
2820 2830 2840 2850 2860 2870
pF1KE2 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
2910 2920 2930 2940 2950 2960
2880 2890 2900 2910 2920 2930
pF1KE2 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
2970 2980 2990 3000 3010 3020
2940 2950 2960 2970 2980 2990
pF1KE2 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
3030 3040 3050 3060 3070 3080
3000 3010 3020 3030 3040 3050
pF1KE2 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
3090 3100 3110 3120 3130 3140
3060 3070 3080 3090 3100 3110
pF1KE2 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
3150 3160 3170 3180 3190 3200
3120
pF1KE2 CPAN
::::
XP_016 CPAN
3210
>>XP_011534122 (OMIM: 156225,607855,618138) laminin subu (3208 aa)
initn: 14009 init1: 7904 opt: 14805 Z-score: 7002.2 bits: 1310.5 E(91774): 0
Smith-Waterman score: 21138; 97.1% identity (97.1% similar) in 3154 aa overlap (57-3122:57-3208)
30 40 50 60 70 80
pF1KE2 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
::::::::::::::::::::::::::::::
XP_011 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE2 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE2 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE2 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE2 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE2 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
330 340 350 360 370 380
390 400 410 420 430 440
pF1KE2 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
390 400 410 420 430 440
450 460 470 480 490 500
pF1KE2 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
450 460 470 480 490 500
510 520 530 540 550 560
pF1KE2 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
510 520 530 540 550 560
570 580 590 600 610 620
pF1KE2 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
570 580 590 600 610 620
630 640 650 660 670 680
pF1KE2 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
630 640 650 660 670 680
690 700 710 720 730 740
pF1KE2 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
690 700 710 720 730 740
750 760 770 780 790 800
pF1KE2 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
750 760 770 780 790 800
810 820 830 840 850 860
pF1KE2 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
810 820 830 840 850 860
870 880 890 900 910 920
pF1KE2 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
870 880 890 900 910 920
930 940 950
pF1KE2 SEVCHSQTGQCECRANVQGQRCDKCK----------------------------------
::::::::::::::::::::::::::
XP_011 SEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCV
930 940 950 960 970 980
pF1KE2 ------------------------------------------------------AGTFGL
::::::
XP_011 CKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGL
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KE2 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KE2 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KE2 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KE2 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KE2 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KE2 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KE2 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KE2 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KE2 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KE2 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KE2 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KE2 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKN--IADADAT
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KE2 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KE2 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KE2 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KE2 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KE2 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KE2 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KE2 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KE2 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
2610 2620 2630 2640 2650 2660
2580 2590 2600 2610 2620 2630
pF1KE2 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
2670 2680 2690 2700 2710 2720
2640 2650 2660 2670 2680 2690
pF1KE2 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
2730 2740 2750 2760 2770 2780
2700 2710 2720 2730 2740 2750
pF1KE2 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
2790 2800 2810 2820 2830 2840
2760 2770 2780 2790 2800 2810
pF1KE2 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
2850 2860 2870 2880 2890 2900
2820 2830 2840 2850 2860 2870
pF1KE2 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
2910 2920 2930 2940 2950 2960
2880 2890 2900 2910 2920 2930
pF1KE2 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
2970 2980 2990 3000 3010 3020
2940 2950 2960 2970 2980 2990
pF1KE2 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
3030 3040 3050 3060 3070 3080
3000 3010 3020 3030 3040 3050
pF1KE2 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
3090 3100 3110 3120 3130 3140
3060 3070 3080 3090 3100 3110
pF1KE2 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
3150 3160 3170 3180 3190 3200
3120
pF1KE2 CPAN
::::
XP_011 CPAN
>>XP_005267039 (OMIM: 156225,607855,618138) laminin subu (3206 aa)
initn: 14713 init1: 10439 opt: 14789 Z-score: 6994.6 bits: 1309.1 E(91774): 0
Smith-Waterman score: 21122; 97.1% identity (97.1% similar) in 3154 aa overlap (57-3122:57-3206)
30 40 50 60 70 80
pF1KE2 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
::::::::::::::::::::::::::::::
XP_005 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE2 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE2 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE2 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
210 220 230 240 250 260
270 280 290 300 310 320
pF1KE2 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE2 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
330 340 350 360 370 380
390 400 410 420 430 440
pF1KE2 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
390 400 410 420 430 440
450 460 470 480 490 500
pF1KE2 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
450 460 470 480 490 500
510 520 530 540 550 560
pF1KE2 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
510 520 530 540 550 560
570 580 590 600 610 620
pF1KE2 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
570 580 590 600 610 620
630 640 650 660 670 680
pF1KE2 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
630 640 650 660 670 680
690 700 710 720 730 740
pF1KE2 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
690 700 710 720 730 740
750 760 770 780 790 800
pF1KE2 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
750 760 770 780 790 800
810 820 830 840 850 860
pF1KE2 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
810 820 830 840 850 860
870 880 890 900 910 920
pF1KE2 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
870 880 890 900 910 920
930 940 950
pF1KE2 SEVCHSQTGQCECRANVQGQRCDKCK----------------------------------
::::::::::::::::::::::::::
XP_005 SEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCV
930 940 950 960 970 980
pF1KE2 ------------------------------------------------------AGTFGL
::::::
XP_005 CKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGL
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KE2 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KE2 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KE2 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KE2 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KE2 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KE2 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KE2 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KE2 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KE2 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KE2 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KE2 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KE2 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KE2 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KE2 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KE2 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KE2 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KE2 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KE2 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KE2 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_005 GLDLKADDKIYFGGLPTLRNL----RPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KE2 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
2610 2620 2630 2640 2650 2660
2580 2590 2600 2610 2620 2630
pF1KE2 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
2670 2680 2690 2700 2710 2720
2640 2650 2660 2670 2680 2690
pF1KE2 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
2730 2740 2750 2760 2770 2780
2700 2710 2720 2730 2740 2750
pF1KE2 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
2790 2800 2810 2820 2830 2840
2760 2770 2780 2790 2800 2810
pF1KE2 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
2850 2860 2870 2880 2890 2900
2820 2830 2840 2850 2860 2870
pF1KE2 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
2910 2920 2930 2940 2950 2960
2880 2890 2900 2910 2920 2930
pF1KE2 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
2970 2980 2990 3000 3010 3020
2940 2950 2960 2970 2980 2990
pF1KE2 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
3030 3040 3050 3060 3070 3080
3000 3010 3020 3030 3040 3050
pF1KE2 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
3090 3100 3110 3120 3130 3140
3060 3070 3080 3090 3100 3110
pF1KE2 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
3150 3160 3170 3180 3190 3200
3120
pF1KE2 CPAN
::::
XP_005 CPAN
>>XP_016866342 (OMIM: 156225,607855,618138) laminin subu (1916 aa)
initn: 13354 init1: 7084 opt: 7333 Z-score: 3480.2 bits: 658.1 E(91774): 4.4e-187
Smith-Waterman score: 12963; 95.3% identity (95.4% similar) in 1904 aa overlap (1-1816:1-1904)
10 20 30 40 50 60
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
850 860 870 880 890 900
910 920 930 940 950
pF1KE2 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCK--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPE
910 920 930 940 950 960
pF1KE2 ------------------------------------------------------------
XP_016 KRFCVLCDCDPVGSVSPQCDITGRCVCKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQ
970 980 990 1000 1010 1020
960 970 980 990
pF1KE2 --------------------AGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVT
::::::::::::::::::::::::::::::::::::::::
XP_016 RWAIGSSSGCPRGAYRAPAPAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVT
1030 1040 1050 1060 1070 1080
1000 1010 1020 1030 1040 1050
pF1KE2 GKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS
1090 1100 1110 1120 1130 1140
1060 1070 1080 1090 1100 1110
pF1KE2 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPG
1150 1160 1170 1180 1190 1200
1120 1130 1140 1150 1160 1170
pF1KE2 TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT
1210 1220 1230 1240 1250 1260
1180 1190 1200 1210 1220 1230
pF1KE2 TQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEP
1270 1280 1290 1300 1310 1320
1240 1250 1260 1270 1280 1290
pF1KE2 FYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMA
1330 1340 1350 1360 1370 1380
1300 1310 1320 1330 1340 1350
pF1KE2 APLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQS
1390 1400 1410 1420 1430 1440
1360 1370 1380 1390 1400 1410
pF1KE2 RISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGP
1450 1460 1470 1480 1490 1500
1420 1430 1440 1450 1460 1470
pF1KE2 TLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACP
1510 1520 1530 1540 1550 1560
1480 1490 1500 1510 1520 1530
pF1KE2 LISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPY
1570 1580 1590 1600 1610 1620
1540 1550 1560 1570 1580 1590
pF1KE2 GSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQM
1630 1640 1650 1660 1670 1680
1600 1610 1620 1630 1640 1650
pF1KE2 VMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLT
1690 1700 1710 1720 1730 1740
1660 1670 1680 1690 1700 1710
pF1KE2 RATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFER
1750 1760 1770 1780 1790 1800
1720 1730 1740 1750 1760 1770
pF1KE2 NLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDL
1810 1820 1830 1840 1850 1860
1780 1790 1800 1810 1820 1830
pF1KE2 REKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTL
:::::::::::::::::::::::::::::::::::::::::::.
XP_016 REKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEQLPAKVIKTNQSI
1870 1880 1890 1900 1910
1840 1850 1860 1870 1880 1890
pF1KE2 KEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQ
>>NP_005550 (OMIM: 150320,615960) laminin subunit alpha- (3075 aa)
initn: 6677 init1: 2247 opt: 7179 Z-score: 3405.3 bits: 644.9 E(91774): 6.6e-183
Smith-Waterman score: 9933; 46.0% identity (72.0% similar) in 3134 aa overlap (6-3120:4-3071)
10 20 30 40 50 60
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
::::.::: : :: .:::::::.::::::: :.:::::::
NP_005 MRGGVLLVLLLC-----VAAQ----------CRQRGLFPAILNLASNAHISTNATCGE
10 20 30 40
70 80 90 100 110 120
pF1KE2 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
:::::.:::::::::.::::::::::. ::.:: .::::..:::: :.:::::::.:: :
NP_005 KGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGRE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
::.:::::::.::::.::::.::::.::::::::::::: . ..::::.::.:.:::. :
NP_005 YHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
:: :: :::.: ::::::::.::.. :::.:::: ::::::::::: ::.:::::::::
NP_005 NITPRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
::::.::::::::::: ..:..:.:.:::::::::::.::::::::::::::: .:: :
NP_005 IRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
.:.: .:.:::::::.::..::::.::.::: :: . . :::::::.::..:::::.::
NP_005 TTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
... ::: :.. :::::::: ::: ::::::: ::..::. ::: .::.::.:::.:
NP_005 KQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVG
350 360 370 380 390 400
430 440 450 460 470
pF1KE2 SLNEVCVKDEKHA--RRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKN
::. ::.::. :. . : ::.: :: :. : .:::: :: :: : .:.:. .:: .
NP_005 SLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSAS
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE2 EDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQ
..:: :::.::::::: :.::: ::.::.: : .::.:::: :::. :.: : :...
NP_005 DEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVN
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE2 DMSGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAV
.:::: .::: . .. ::: : . .:.::.:. . : : .:::.:: :::::: :
NP_005 SMSGWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAF
530 540 550 560 570 580
600 610 620 630 640 650
pF1KE2 GGQLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEE
:: : .:.:::. : :.. . . .:..:: :..:: . . :.: ::. ::. : :
NP_005 GGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPE
590 600 610 620 630 640
660 670 680 690 700 710
pF1KE2 SFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIA
.: .. . : ..::::::. ..:.. .:. . :..:: ::.:. : : : .:
NP_005 NFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVA
650 660 670 680 690 700
720 730 740 750 760 770
pF1KE2 AAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKD
: :: :.:: ::::.::::: . ::.: .:::::.::.: ::: :. : : :. :
NP_005 ADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECN-VHGVCIACAH
710 720 730 740 750 760
780 790 800 810 820 830
pF1KE2 HTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVG
.: : .:..:::::::::..:: :::::::::.: ::::::::::. . ..:: : :
NP_005 NTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPG
770 780 790 800 810 820
840 850 860 870 880 890
pF1KE2 YTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYC
:.: :::::.::.:.:.::: :: ::.:. :.: : : :::..: :: : .: : .:
NP_005 YSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC
830 840 850 860 870 880
900 910 920 930 940 950
pF1KE2 ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL
: ::::..:::: ::::. :.:.. :: : ::: .:: :.:. :: ::.::.: : .::
NP_005 ERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
.:..:: ::::. :: : : . ::: : :::.::.:::::::.. .:.:.:: :.: :
NP_005 DSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPH
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
:.:::.::.:.:::.: : :: .: . ::.. .::.::::: ::: .:.: ::.
NP_005 TQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGH
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
:.:. ::.: : .:: :. ..: : ::: : ::.. .:. : :.: ..:: : ::
NP_005 CQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKE
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
:: : .:..:: : :.: : :::::: :.: : . ::: . .:: ::: ..: .: .:
NP_005 NVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVV
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
... . ::.:. .: :... .:. .. :::::.::.::.: .::::::::::..
NP_005 SQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVA
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
: . . .: :...:::.:.:: . ..: :: : ..:. : :. :::. .
NP_005 FYSLDGVGTSNFEPQVLIKGGR-IRKQVIYMDAPAPENGVRQEQEVAMRENFWKYF--NS
1250 1260 1270 1280 1290
1320 1330 1340 1350 1360 1370
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPP----A
.. ::::::...: ::.::::::.::. ..:::::.::::: :: . : :
NP_005 VSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEV---GRKAEKLHPEEEVA
1300 1310 1320 1330 1340 1350
1380 1390 1400 1410 1420 1430
pF1KE2 DLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGG-RTPGPTLGTCVPCQCNGHSSLCDPET
.:.:.: :: : :.::. : ::..: . :. : : : .. ::::.::.::. :::.:
NP_005 SLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNT
1360 1370 1380 1390 1400 1410
1440 1450 1460 1470 1480 1490
pF1KE2 SICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYR
. : :: .:::: :. :. :::: : : .:: :::: : .:::.:: :: :.:
NP_005 GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPH-SPPASFSPTCVLEGDHDFR
1420 1430 1440 1450 1460 1470
1500 1510 1520 1530 1540 1550
pF1KE2 CTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGAT
: :: ::::..::::. .: :.: .::::::.:.:.:.::. :: ..: :.:: ::.
NP_005 CDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGAS
1480 1490 1500 1510 1520 1530
1560 1570 1580 1590 1600 1610
pF1KE2 GRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLE
: .:: :. : .:: : :::.:.::.:: .. . :.:.:::: .:.:: .: .::
NP_005 GLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLE
1540 1550 1560 1570 1580 1590
1620 1630 1640 1650 1660 1670
pF1KE2 NMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNT
: :. :.. : . . : .. .:. .. : ..: . :.. :. ..... .::
NP_005 NTTKYLQESLLKENMQKDLGKI---KLEGVAEETDNLQKKLTRMLASTQKVNRATERIFK
1600 1610 1620 1630 1640 1650
1680 1690 1700 1710 1720 1730
pF1KE2 RAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAF---ERNLEGLQKEIDQMIKELRR
....:. :..: . . ::. ::.:: :: : . .:...:.. .... ..
NP_005 ESQDLAIAIERLQMSITEIMEKTT-LNQTL---DEDFLLPNSTLQNMQQNGTSLLEIMQI
1660 1670 1680 1690 1700
1740 1750 1760 1770 1780 1790
pF1KE2 KNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLL
... .. : :: ::: ::..... . . : : ... . :. ..:.. : :.
NP_005 RDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALV
1710 1720 1730 1740 1750 1760
1800 1810 1820 1830 1840 1850
pF1KE2 REATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEIN
::: :..:.:.:. . . :. . :: :. . . . .: ..: : .: ..
NP_005 REAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQ
1770 1780 1790 1800 1810 1820
1860 1870 1880 1890 1900 1910
pF1KE2 SIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGI
. ....:: : :: : .. .:::: .....:. .. : .::.:::... . :: .
NP_005 DALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSG
1830 1840 1850 1860 1870 1880
1920 1930 1940 1950 1960 1970
pF1KE2 LDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGC
:.. .:.:.:::.: .. ::.. :.:.:..:..:. . :.. :. . : ..:.
NP_005 LENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLLSES----LVSNGKAA
1890 1900 1910 1920 1930 1940
1980 1990 2000 2010 2020 2030
pF1KE2 LQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDT
.:.: :.:.:...:. . .:. :... . . .. : :..: : :::.
NP_005 VQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGI
1950 1960 1970 1980 1990 2000
2040 2050 2060 2070 2080 2090
pF1KE2 AAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNK
: .:. : .:...: ..: ... : :.: . . . ... .. .:. ...: .
NP_005 RDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMAT
2010 2020 2030 2040 2050 2060
2100 2110 2120 2130 2140 2150
pF1KE2 IIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSS
..: ::..: .:. :.:.:::.: ::.::..:.:::: ::.:::::: ::::.::.
NP_005 LLAGR--KVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSA
2070 2080 2090 2100 2110 2120
2160 2170 2180 2190 2200 2210
pF1KE2 GGDCIRTYKPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDV
::::.:.:.:.. .::....:::: :::::::::. ::::.:::.:.:.::::.
NP_005 DRDCIRAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDL
2130 2140 2150 2160 2170 2180
2220 2230 2240 2250 2260 2270
pF1KE2 GSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTI
::: :.:.::. :::. :. : ..: : :..::. ... . : : :. : :: ..
NP_005 GSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKS--P-TKTSKSPGTANV
2190 2200 2210 2220 2230
2280 2290 2300 2310 2320 2330
pF1KE2 LDVDANAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTV
:::. ....::::: :..::. ::.: : ::.::.....: :::::. :.:: :.::
NP_005 LDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKCRGCFG
2240 2250 2260 2270 2280 2290
2340 2350 2360 2370 2380
pF1KE2 SPQVEDSEGTIQFDGEGYALVSRPIRWYP-NISTVMFKFRTFSSSALLMYLATRDLRDFM
: : :: ...::: ::..: . . : ... ... : ::: ..::.::.. .::.
NP_005 SSQNEDP--SFHFDGSGYSVVEKSL---PATVTQIIMLFNTFSPNGLLLYLGSYGTKDFL
2300 2310 2320 2330 2340 2350
2390 2400 2410 2420 2430 2440
pF1KE2 SVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDI-DTNQEEN
:.:: :..:: ::::: ...... .:.: : .....: .::. ....: .:...:.
NP_005 SIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKET
2360 2370 2380 2390 2400 2410
2450 2460 2470 2480 2490 2500
pF1KE2 IATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNI
. : . :. : :: :::: : . : :. :.. ::.:..::::. ...
NP_005 KQGETPGASSDLNRLDKDPIYVGGLPRSRVV----RRGVTTKSFVGCIKNLEISRSTFDL
2420 2430 2440 2450 2460 2470
2510 2520 2530 2540 2550 2560
pF1KE2 LSSPDYVGVTKGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSG
: . :: ::: :: . .::: : :..:: : .. .: ..:.: : ::::: . :
NP_005 LR--NSYGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSSGIILAALG
2480 2490 2500 2510 2520
2570 2580 2590 2600 2610 2620
pF1KE2 GTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGART-MRKIVIRPEPNLFHDGREHSVH
: . : :... .. ..: : .:::.. : : .:: ... . ::. ::.
NP_005 GD-VEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSIS
2530 2540 2550 2560 2570 2580
2630 2640 2650 2660 2670 2680
pF1KE2 VERTRGIFTVQVDENRRYMQNL--TVE-QPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCI
. :.: :.:::.::: ..: :: . :.:..:.::: : : : :.:::
NP_005 LVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCI
2590 2600 2610 2620 2630 2640
2690 2700 2710 2720 2730 2740
pF1KE2 WNLVINSVPMDFARPVSFKNADIGRCAHQKLREDEDGAAPAEIV-IQPEPVPTPAFPTPT
::..: .:: :. ...:. : : : : :: . ::: :::
NP_005 KNLIFNLELLDFNSAVGHEQVDLDTCW---LSERPKLAPDAEDSKLLPEP---RAFPEQ-
2650 2660 2670 2680 2690 2700
2750 2760 2770 2780 2790 2800
pF1KE2 PVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLF
:.... . :..::::..:::. . :... :...:..:: .:: : :::..
NP_005 -------CVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIY
2710 2720 2730 2740 2750
2810 2820 2830 2840 2850 2860
pF1KE2 YMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYV
:::. :.::.:..::..: .: .:::.: :.. :. ..::.:: .: :..:.. :
NP_005 YMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITV
2760 2770 2780 2790 2800 2810
2870 2880 2890 2900 2910 2920
pF1KE2 DGASNRTISP-KKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADL
:: . .. . .::: :..:.:::: .: .:.:: .:.:: .:. .. . :
NP_005 DGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDK
2820 2830 2840 2850 2860 2870
2930 2940 2950 2960 2970 2980
pF1KE2 EQPTSSFHVGTCFANAQRGTYFDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGIS
..:.:.: :. :.: ::.::::::.:.: : :.:: :. . .::::.. .:::::::
NP_005 DSPVSAFTVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGIS
2880 2890 2900 2910 2920 2930
2990 3000 3010 3020 3030 3040
pF1KE2 SQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTV
. :.:..:.:..: :..:::.:::::.::.:. . ::::.:: . ::: :::: : :
NP_005 TAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIV
2940 2950 2960 2970 2980 2990
3050 3060 3070 3080 3090 3100
pF1KE2 DGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPL
::: : :.::. :::.:::.:..:::.: .:: : .. ::::.:.: : : . .
NP_005 DGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIK-SPQVQ
3000 3010 3020 3030 3040 3050
3110 3120
pF1KE2 EVNFAKALELRGVQPVSCPAN
.:..:.::.:: :::
NP_005 SFDFSRAFELHGVFLHSCPGTES
3060 3070
>>XP_011524284 (OMIM: 226650,226700,245660,600805) lamin (3243 aa)
initn: 2076 init1: 743 opt: 1426 Z-score: 691.4 bits: 142.8 E(91774): 9.6e-32
Smith-Waterman score: 3420; 26.7% identity (51.6% similar) in 3393 aa overlap (29-3039:37-3165)
10 20 30 40 50
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATC
:. : .: :. .::: : : ..:::
XP_011 PRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATC
10 20 30 40 50 60
60 70 80 90 100
pF1KE2 GEKGP-------EMYCKLV--EHVPG--QPVRNPQCRICNQNSSNPNQRHPITNAIDGKN
::.:: :.::::: .:: . ... : :: : .: . ::.::::::..
XP_011 GERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCN--SEDPRKAHPVTNAIDGSE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 TWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPW
::::: ...: .:. :..:::: :.:..::...: :::::: :.::::.: :.::
XP_011 RWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPW
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 QYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSAD
:: : . ..:: .. : . . ..::.:.:.. ::.: ::::::. .:::::::.:
XP_011 QYFAHSKVDCLKEFG---REANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 DP--SPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVG
. : : :::.: ::::: : :: . :. :..:: ::::::::.::::.:
XP_011 NFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDP-----TVTRRYYYSIKDISIG
250 260 270 280 290
290 300 310 320 330 340
pF1KE2 GMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEAC
:.:.: :::..: .. . ::::.:.:::..::.:: :..:. :: ... . :::::
XP_011 GQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEAC
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE2 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS
::::.: .:::: .: :.. ::: .: : :::::::: .::::.::: :. :..:: ::
XP_011 NCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP
360 370 380 390 400 410
410 420
pF1KE2 PNYPRPCQPCHCDP----------------------------IGSLN-EVCVK-------
. : : :: ::: :: : :..
XP_011 VDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVS
420 430 440 450 460 470
430 440 450 460
pF1KE2 ----------DEKHAR---RGLAP------GSCHCKTGFGGVSCDRCARGYTGYPDCKAC
: : .:. : : : :. : : :: : :. ..: :.::
XP_011 TPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQAC
480 490 500 510 520 530
470 480
pF1KE2 NCSGLGS--------------------KNEDPCF--------------------------
::.::: . : :.
XP_011 WCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNL
540 550 560 570 580 590
490 500 510
pF1KE2 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC-------------------------
: : :: .::: ::::: ..::...: .::.::
XP_011 GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKS
600 610 620 630 640 650
520 530
pF1KE2 --------------------------------------FCSGVSNRCQSSYWTYGKI--Q
.::: :. :: . ::. .
XP_011 HVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR
660 670 680 690 700 710
540 550 560
pF1KE2 DMSGWYLTDL------------P-GR-IRVA------PQ------------QDDLDSPQQ
...:. :: : :: .: . :. :.:. .
XP_011 PENNYYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLN
720 730 740 750 760 770
570 580 590
pF1KE2 ISISNAEA-----RQALP-------H-SYY--W-------SAPAPYLGNKLPAV------
.. :.. : . : : . : : : .: .: ::
XP_011 VGKSSGSLFRVILRYVNPGTEAVSGHITIYPSWGKARAAQSKEIIFLPSKEPAFVTVPGN
780 790 800 810 820 830
600 610 620 630 640 650
pF1KE2 GGQLTFTISYDLEEEEEDTERVLQLMIIL------EGNDLSISTAQDEVYLHPSEEHT--
: :.:. . .: :: ...: :.. :.. ... .: : .:..
XP_011 GFADPFSITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQEKSVW
840 850 860 870 880 890
660 670 680 690
pF1KE2 --NVLLLKE--------------ESFTIHGTHFPVRRKE---FMTVLANLKRVLLQITYS
. :: .. . : . : :: .. :...:. ...
XP_011 GRSCLLYQHLPVTRFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLR
900 910 920 930 940 950
700 710 720 730 740
pF1KE2 FGMDAIFRLSSV---NLESA------VSYPTDGSI-AAAVEVCQCPPGYTGSSCESCWPR
. . . . : . :.: :. ..::. :. :.. .: .:. :.:
XP_011 LRIPQVGHYVVVVEYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSC--NYS-VLCRSAVID
960 970 980 990 1000 1010
750 760 770 780 790
pF1KE2 H-RRVNGTIFGGICEP-CQCFGHA------ESCDDVTGECLNCKDHTGGPYCDKCLPGFY
: :. ... . . : :: . : . : .. . .: :
XP_011 HMSRI--AMYELLADADIQLKGHMARFLLHQVCI-IPIEEFSAEYVRPQVHCIASYGRFV
1020 1030 1040 1050 1060 1070
800 810 820 830 840 850
pF1KE2 GEPTKGTS--EDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCP-VGYTGPRCERCAEG
.. . .: .. : : :.. :. : :: .. . : : : .:. . .:
XP_011 NQSATCVSLAHETPPTALILDVLSG--RPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRG
1080 1090 1100 1110 1120
860 870 880 890 900
pF1KE2 ---YFGQPSVPGGSCQPCQCNDNLDFSIPGS---CDSLSGSCLICKPGTTGRYCELCADG
..:. : . . . :. :. :. .: .: : . : .. :.:
XP_011 RVPHLGRYVFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHAS--FC-PHVLGCRDQVIAEG
1130 1140 1150 1160 1170 1180
910 920 930 940
pF1KE2 YFG-DAVDAKNCQPCRCNAGGSFS--------------EVCHSQTGQ------CECRAN-
. : . . . : :. .. :... . .: :
XP_011 QIEFDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNS
1190 1200 1210 1220 1230 1240
950 960 970 980 990
pF1KE2 --VQGQRCDK-CKAGTFGLQS--ARGCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGKKC
.. : .. :: .. .: . .: .::.:. :. . : :.::: :::.: :..:
XP_011 FYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQC
1250 1260 1270 1280 1290 1300
1000 1010 1020 1030 1040 1050
pF1KE2 DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG
::: :...: . : : :.. :. ::.: ::: :. .: : .... .:
XP_011 TRCATGHYGFPR--CKPCSCGR--RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAG
1310 1320 1330 1340 1350 1360
1060 1070 1080 1090 1100 1110
pF1KE2 CKACNCSTVGSLDF---QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGT
:..:::: :... .:. ..::: :.:...: .: .:. : . .:.: :.: ::
XP_011 CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT
1370 1380 1390 1400 1410 1420
1120 1130 1140 1150 1160 1170
pF1KE2 DATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTT
. .:: :: : :: :::: .:. :: :.: :: : ::.::.:::...
XP_011 EPGVCDP---------GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNN
1430 1440 1450 1460 1470
1180 1190 1200 1210 1220 1230
pF1KE2 QCSEAKGLIRTWVTLKAEQTILPLVDEA-LQHTTTKGIVFQHPEIVAHMDLMREDLHLEP
:: .. .: . . . : .:.. . . . : .:: .. . .:
XP_011 QCHSSHKRRTKFVDMLGWH--LETADRVDIPVSFNPG----SNSMVADLQELPATIHSAS
1480 1490 1500 1510 1520
1240 1250 1260 1270 1280 1290
pF1KE2 FYWKLPEQFEGKKLMAYGGKLKY-AIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHM
: : .. : :. .::: : : : : . . .:.: . : : :: ..
XP_011 --WVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTG---QHMSIIYEET
1530 1540 1550 1560 1570 1580
1300 1310 1320 1330 1340 1350
pF1KE2 AAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQ
.: .: . .....: .... .. . :.::... .: . . :.. : . ..
XP_011 NTPRPDRLHHGRVHVVEGNFRHASS----RAPVSREELMTVLSRLADVRIQGLYFTETQR
1590 1600 1610 1620 1630
1360 1370 1380 1390 1400 1410
pF1KE2 SRISEISMEVA-EQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTP
.::...: : . : : : .: : :: .:.: ::..: ::.:: .. : :
XP_011 LTLSEVGLEEASDTGSGRI----ALAVEICACPPAYAGDSCQGCSPGYYR--DHKGLYT-
1640 1650 1660 1670 1680 1690
1420 1430 1440 1450 1460 1470
pF1KE2 GPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCA
: ::::.:::::. :. ..:: ::::.:::. :::: :::: ... ..:. :
XP_011 ----GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACP
1700 1710 1720 1730 1740
1480 1490 1500 1510 1520 1530
pF1KE2 CPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECD
:: .:.:. .::..: : ::. : :: : :::::::: :.: . ::::: : :.
XP_011 CP---HTNSFATGCVVNG-GDVRCS-CKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCN
1750 1760 1770 1780 1790
1540 1550 1560 1570 1580
pF1KE2 PYGSLPVPCDPVTGFCTC---RPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLA
:.: : :.:: : . .. ...:: : : :. ::.:::
XP_011 SNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC---------------DSCVMTLLNDLA
1800 1810 1820 1830 1840
1590 1600 1610 1620 1630 1640
pF1KE2 RL-EQMVMSINLTGPLPAPYKMLYGLENMTQELK----HLLSPQRAPERLIQLAEGNLNT
. ::. . . : : .: ...: . : .::. . : . :: :.
XP_011 TMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEG-LER
1850 1860 1870 1880 1890 1900
1650 1660 1670 1680 1690
pF1KE2 LVTEMN---ELLTRATKVTADGEQT-GQDAERTNTRAKSLGEFIKELARDAEAVNEKAIK
.:..: : : . ..:.. :: .....:.. :: : ::.. :... . . .
XP_011 ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLK---Q
1910 1920 1930 1940 1950
1700 1710 1720 1730 1740 1750
pF1KE2 LNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLF
.. : : ... .. : ..:..::: .:. . . :: . .. ::....
XP_011 ISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQ
1960 1970 1980 1990 2000 2010
1760 1770 1780 1790 1800 1810
pF1KE2 GESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKK
.:::. . ...:..: .:. :..: :.::. . ..:: : :.. . :....
XP_011 KTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQV
2020 2030 2040 2050 2060 2070
1820 1830 1840 1850 1860 1870
pF1KE2 EAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLS
. ..: . .. . : ... : ..: . ... : . ..: .::.::. .::
XP_011 KEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELS
2080 2090 2100 2110 2120 2130
1880 1890 1900 1910 1920 1930
pF1KE2 QEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKN--ISFNATAAFKAYSNIKDYID
. .:.: .::.:: .:.. . :. : .:.. . :. : :: :: . :
XP_011 RSAGKTSLVE---EAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIK
2140 2150 2160 2170 2180 2190
1940 1950 1960 1970 1980 1990
pF1KE2 EAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLN
:: .:..: . .. : : : . : . :: ..: ..::::: . .:. .:
XP_011 AAEDAANRAASASESA--LQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQ----VN
2200 2210 2220 2230 2240 2250
2000 2010 2020 2030 2040 2050
pF1KE2 GLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQIT
: ... :: : ... .: . : . ... ... .:: :.:. : . .
XP_011 KLTNKLP-------DLWRKIESINQQLLPLGN-ISDNMDRIRELIQQARDAASKVAVPMR
2260 2270 2280 2290 2300
2060 2070 2080 2090 2100 2110
pF1KE2 ELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPI
..: :... :. :. . . . :.. .:
XP_011 -----FNG-------------KSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR--------
2310 2320 2330
2120 2130 2140 2150 2160 2170
pF1KE2 KELEDNLKKNISEIKELINQARKQANSIKVSVSSGG-DCIRTYKPEIKKGSYNNIVVN--
:.. .:. . : :. .. . : ..: .: :. . . . . ..:...
XP_011 ---ENGGTENMF-VMYLGNKDASR-DYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSE
2340 2350 2360 2370 2380 2390
2180 2190 2200 2210 2220 2230
pF1KE2 VKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIV
.: :: : . : .. .: ... :: .: .. : : :
XP_011 TKEAVMDRVKFQ----RIYQFARLNYTKGATS---------SKPETPG-----------V
2400 2410 2420
2240 2250 2260 2270 2280 2290
pF1KE2 ASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDA-NAMLFVGGLTGKLKKAD
. :::.. :.:..: :....::: .: .
XP_011 YDMDGRNSN--------------------------TLLNLDPENVVFYVGGYPPDFKLPS
2430 2440 2450 2460
2300 2310 2320 2330 2340
pF1KE2 AVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSP---QVEDSEGTIQFDGEGYA
. . ::. .... ..:.::. : . . : : . :.:. . :.: :::
XP_011 RLSFPPYKGCIELDDLNENVLSLYNFK-KTFNLNTTEVEPCRRRKEESDKNY-FEGTGYA
2470 2480 2490 2500 2510
2350 2360 2370 2380 2390 2400
pF1KE2 LVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMA
: : . . : : ..: . .::.. . : :.:... ::.. : : :.: .
XP_011 RV--PTQPHAPIPTFGQTIQTTVDRGLLFFAENGD--RFISLNIEDGKLMVRYKLNSELP
2520 2530 2540 2550 2560 2570
2410 2420 2430 2440 2450 2460
pF1KE2 SVVSNQNH-NDGKWKSFTLS--RIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADD
. . . :.:. .:. .. ..::. :. ::... : .:. : ..
XP_011 KERGVGDAINNGRDHSIQIKIGKLQKRMWIN-VDVQN-------TIIDGEVFDFST----
2580 2590 2600 2610 2620
2470 2480 2490 2500 2510 2520
pF1KE2 KIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLEN-
:.::.: .... : ... . ::.:.. . ... : ::::: :: .
XP_011 -YYLGGIP----IAIRERFNISTPAFRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDWK
2630 2640 2650 2660 2670
2530 2540 2550 2560 2570 2580
pF1KE2 -VYTVSFPKPG---FVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQT
: ..:: . : :..:. : : . ...:.: . :::.: .::
XP_011 LVRSASFSRGGQLSFTDLGLPPTD-HLQASFGFQTFQPSGILL-------------DHQT
2680 2690 2700 2710 2720
2590 2600 2610 2620 2630 2640
pF1KE2 GQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDE
. :. : .:. : .. . : :. . :: : : : . . . .:.
XP_011 WTRNLQVTLEDGYIELSTSDSGGPIFK-----SPQTYMDGLLHYVSVISDNSGLRLLIDD
2730 2740 2750 2760 2770
2650 2660 2670 2680 2690
pF1KE2 ----NRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSV---P-
: . ..... . ..: .::. ::::: :. .. . :
XP_011 QLLRNSKRLKHISSSR----QSLRLGGSN-------------FEGCISNVFVQRLSLSPE
2780 2790 2800 2810
2700 2710 2720 2730 2740
pF1KE2 -MDFARPVSFKNADIGRCAHQK----------LREDEDGAAPAEIVIQPEPVPTPAFPTP
.:.. .....: :. .: : .. . . ..: :: .:
XP_011 VLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPR----
2820 2830 2840 2850 2860 2870
2750 2760 2770 2780 2790 2800
pF1KE2 TPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLL
. . . :. . :. ::: .::. . . . .: : . ....: . ::.
XP_011 SVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLV
2880 2890 2900 2910 2920 2930
2810 2820 2830 2840 2850 2860
pF1KE2 FYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIKIMRSKQEGI
:. . : .: .. : .: :. ::. . : .: :::.:: . . .. ..:
XP_011 FHTGTKN--SFMALYLSKGRLVFA--LGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGR
2940 2950 2960 2970 2980 2990
2870 2880 2890 2900 2910 2920
pF1KE2 LYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPA
: ::: : : . ... . .:.:. : . . . : : :. ::..:... :
XP_011 LVVDGLRAREGSLPGNSTISIRAPVYLGS-PPSGKPKSL-P-TNSFVGCLKNFQLDSKP-
3000 3010 3020 3030 3040
2930 2940 2950 2960 2970
pF1KE2 DLEQPTSSFHVGTCFANA-QRGTYFDGTGFAKAVGGFKV--GLDLLVEFEFRTTTTTGVL
: :.::: :..:... ..: ::. : ...: . .: : .. . : .: . ::.:
XP_011 -LYTPSSSFGVSSCLGGPLEKGIYFSEEG-GHVVLAHSVLLGPEFKLVFSIRPRSLTGIL
3050 3060 3070 3080 3090 3100
2980 2990 3000 3010 3020 3030
pF1KE2 LGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGH-LCDGQWHKVTANKIKHR
. :.:: . . . :. .:.::: .. . .: . :::::::.:... .:
XP_011 IHIGSQPGKHLCVYLEAGKVTASMDSGAG---GTSTSVTPKQSLCDGQWHSVAVTIKQHI
3110 3120 3130 3140 3150 3160
3040 3050 3060 3070 3080 3090
pF1KE2 IELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKG
..:
XP_011 LHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIP
3170 3180 3190 3200 3210 3220
3122 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:51:41 2019 done: Tue Jul 16 15:51:44 2019
Total Scan time: 13.940 Total Display time: 2.420
Function used was FASTA [36.3.4 Apr, 2011]