Result of FASTA (omim) for
pFN21AE1097
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1097, 606 aa
1>>>pF1KE1097 606 - 606 aa - 606 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0178+/-0.000543; mu= -2.7165+/- 0.034
mean_var=533.6816+/-112.402, 0's: 0 Z-trim(122.0): 407 B-trim: 1983 in 2/55
Lambda= 0.055518
statistics sampled from 38939 (39376) to 38939 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.462), width: 16
Scan time: 12.760
The best scores are: opt bits E(85289)
XP_016869024 (OMIM: 602728) PREDICTED: scavenger r ( 606) 4097 343.1 1.6e-93
NP_057324 (OMIM: 602728) scavenger receptor class ( 606) 4097 343.1 1.6e-93
NP_878185 (OMIM: 602728) scavenger receptor class ( 466) 2948 251.0 6.8e-66
XP_016869026 (OMIM: 602728) PREDICTED: scavenger r ( 483) 2948 251.0 6.9e-66
XP_016869025 (OMIM: 602728) PREDICTED: scavenger r ( 490) 2948 251.0 7e-66
NP_569057 (OMIM: 607621) collectin-12 [Homo sapien ( 742) 1249 115.2 8.3e-25
XP_011524043 (OMIM: 607621) PREDICTED: collectin-1 ( 725) 1238 114.3 1.5e-24
XP_005257116 (OMIM: 114000,120150,130000,130060,16 (1158) 559 60.1 4.7e-08
XP_005257115 (OMIM: 114000,120150,130000,130060,16 (1374) 559 60.2 5.3e-08
XP_011522643 (OMIM: 114000,120150,130000,130060,16 (1398) 559 60.2 5.3e-08
NP_000079 (OMIM: 114000,120150,130000,130060,16620 (1464) 559 60.3 5.5e-08
XP_016883155 (OMIM: 120270,600969,603932) PREDICTE ( 486) 544 58.4 6.4e-08
XP_011532992 (OMIM: 610043) PREDICTED: collagen al ( 548) 545 58.6 6.5e-08
XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 554 59.8 6.7e-08
NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418) 554 59.8 7.1e-08
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 556 60.1 7.1e-08
XP_016874319 (OMIM: 108300,120140,132450,150600,15 (1465) 554 59.9 7.2e-08
NP_000081 (OMIM: 120180,130020,130050) collagen al (1466) 554 59.9 7.2e-08
NP_001835 (OMIM: 108300,120140,132450,150600,15121 (1487) 554 59.9 7.3e-08
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 556 60.2 7.4e-08
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 556 60.2 7.4e-08
XP_016874318 (OMIM: 108300,120140,132450,150600,15 (1534) 554 59.9 7.4e-08
XP_016874317 (OMIM: 108300,120140,132450,150600,15 (1535) 554 59.9 7.4e-08
XP_011508875 (OMIM: 120190,130000) PREDICTED: coll (1453) 553 59.8 7.6e-08
NP_000384 (OMIM: 120190,130000) collagen alpha-2(V (1499) 553 59.8 7.7e-08
XP_016855826 (OMIM: 120280,154780,228520,603932,60 (1323) 546 59.2 1.1e-07
XP_016855825 (OMIM: 120280,154780,228520,603932,60 (1515) 546 59.2 1.1e-07
NP_542197 (OMIM: 120280,154780,228520,603932,60484 (1690) 546 59.3 1.2e-07
NP_001177638 (OMIM: 120280,154780,228520,603932,60 (1767) 546 59.3 1.3e-07
NP_001845 (OMIM: 120280,154780,228520,603932,60484 (1806) 546 59.3 1.3e-07
NP_542196 (OMIM: 120280,154780,228520,603932,60484 (1818) 546 59.3 1.3e-07
XP_016855824 (OMIM: 120280,154780,228520,603932,60 (1855) 546 59.4 1.3e-07
XP_016855823 (OMIM: 120280,154780,228520,603932,60 (1857) 546 59.4 1.3e-07
NP_536800 (OMIM: 603033,603034) acetylcholinestera ( 421) 527 57.0 1.5e-07
NP_536799 (OMIM: 603033,603034) acetylcholinestera ( 445) 527 57.0 1.6e-07
NP_005668 (OMIM: 603033,603034) acetylcholinestera ( 455) 527 57.0 1.6e-07
XP_006714998 (OMIM: 610043) PREDICTED: collagen al ( 554) 529 57.3 1.6e-07
XP_016884752 (OMIM: 301050,303630) PREDICTED: coll (1136) 536 58.3 1.7e-07
XP_016882338 (OMIM: 120216) PREDICTED: collagen al ( 966) 532 57.9 1.9e-07
XP_011533734 (OMIM: 120110,156500) PREDICTED: coll ( 680) 528 57.4 1.9e-07
NP_000484 (OMIM: 120110,156500) collagen alpha-1(X ( 680) 528 57.4 1.9e-07
XP_016865738 (OMIM: 120110,156500) PREDICTED: coll ( 680) 528 57.4 1.9e-07
XP_006715396 (OMIM: 120110,156500) PREDICTED: coll ( 680) 528 57.4 1.9e-07
XP_011533735 (OMIM: 120110,156500) PREDICTED: coll ( 680) 528 57.4 1.9e-07
XP_016865737 (OMIM: 120110,156500) PREDICTED: coll ( 680) 528 57.4 1.9e-07
NP_690850 (OMIM: 610025) collagen alpha-1(XXIV) ch (1714) 537 58.6 2e-07
XP_011532990 (OMIM: 610043) PREDICTED: collagen al ( 557) 524 56.9 2.1e-07
XP_006714999 (OMIM: 610043) PREDICTED: collagen al ( 545) 520 56.6 2.6e-07
XP_011532994 (OMIM: 610043) PREDICTED: collagen al ( 472) 518 56.3 2.7e-07
XP_011526344 (OMIM: 120216) PREDICTED: collagen al (1744) 532 58.2 2.7e-07
>>XP_016869024 (OMIM: 602728) PREDICTED: scavenger recep (606 aa)
initn: 4097 init1: 4097 opt: 4097 Z-score: 1800.1 bits: 343.1 E(85289): 1.6e-93
Smith-Waterman score: 4097; 100.0% identity (100.0% similar) in 606 aa overlap (1-606:1-606)
10 20 30 40 50 60
pF1KE1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP
550 560 570 580 590 600
pF1KE1 GSQSFY
::::::
XP_016 GSQSFY
>>NP_057324 (OMIM: 602728) scavenger receptor class A me (606 aa)
initn: 4097 init1: 4097 opt: 4097 Z-score: 1800.1 bits: 343.1 E(85289): 1.6e-93
Smith-Waterman score: 4097; 100.0% identity (100.0% similar) in 606 aa overlap (1-606:1-606)
10 20 30 40 50 60
pF1KE1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPP
550 560 570 580 590 600
pF1KE1 GSQSFY
::::::
NP_057 GSQSFY
>>NP_878185 (OMIM: 602728) scavenger receptor class A me (466 aa)
initn: 2948 init1: 2948 opt: 2948 Z-score: 1304.0 bits: 251.0 E(85289): 6.8e-66
Smith-Waterman score: 2948; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:1-457)
10 20 30 40 50 60
pF1KE1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR
:::::::::::::::::::::::::::::::::::::
NP_878 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGHTLFSHNRI
430 440 450 460
490 500 510 520 530 540
pF1KE1 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK
>>XP_016869026 (OMIM: 602728) PREDICTED: scavenger recep (483 aa)
initn: 2948 init1: 2948 opt: 2948 Z-score: 1303.8 bits: 251.0 E(85289): 6.9e-66
Smith-Waterman score: 2949; 95.3% identity (96.9% similar) in 486 aa overlap (1-486:1-477)
10 20 30 40 50 60
pF1KE1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR
::::::::::::::::::::::::::::::::::::: :.. . ::.. .:
XP_016 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGN------RNLDLQEGVES---SR
430 440 450 460 470
490 500 510 520 530 540
pF1KE1 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK
. :.:
XP_016 SAPGNPTVSRRK
480
>>XP_016869025 (OMIM: 602728) PREDICTED: scavenger recep (490 aa)
initn: 2948 init1: 2948 opt: 2948 Z-score: 1303.8 bits: 251.0 E(85289): 7e-66
Smith-Waterman score: 2948; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:1-457)
10 20 30 40 50 60
pF1KE1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKGRPGPRCSRCQKNLSLHTSVRILYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGLDPKALNNCSFCH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQNSESMHDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGR
:::::::::::::::::::::::::::::::::::::
XP_016 SARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGNRNLDLQEGVESSRSDHSFRTCC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 GPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPK
XP_016 IWGWHHFPFE
490
>>NP_569057 (OMIM: 607621) collectin-12 [Homo sapiens] (742 aa)
initn: 1856 init1: 889 opt: 1249 Z-score: 566.3 bits: 115.2 E(85289): 8.3e-25
Smith-Waterman score: 1249; 35.0% identity (67.0% similar) in 588 aa overlap (17-601:2-581)
10 20 30 40 50
pF1KE1 MKVRSAGGDGDALCVTEEDLAGDDEDMPTFPCTQKG-RPGPRCSRCQKNLSLHTSVRILY
..:.: ..:.. .: . : . : .:..:..: .:. :. .::
NP_569 MKDDFA-EEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLY
10 20 30 40
60 70 80 90 100 110
pF1KE1 LFLALLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGL-DPKALNNCSF
.. ::: ..::.:. : .:.:... . ... :: ::. ....:. : : . . :
NP_569 ILCALLTITVAILGYKVVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAIST
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 CHEAGQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSI
: . . .: :...:. : . .. :.. . ..: . :... . . :: :
NP_569 NSELSTFRSDILDLRQQLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 HQVNQSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQ
::..: . . : . : :. :. .:.. : ....:.: : . : ..:
NP_569 TTVNKTLQAYNGYVTNLQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 RKTDEETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQ-NSESM
:..:. . ..:.: .:.:: ..: . . : :...: ::.:... ... :....
NP_569 RSVDDTSQAIQRIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQ-TLAANNSALAKANNDTL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 HDLVLQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEI
.:. :. .. :..::... . .:.:..::: . :.:::. .:..:: :. : .:
NP_569 EDMNSQLNSFTGQMENITTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDI
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 GTIFTNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERF
.:..::. : .:.... . :..:: .:: . :...: ::.... . . :: .
NP_569 VNIISNISYTAHHLRTLTSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQ
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE1 SLLSARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPV
.:. .::: .: :::.:.:::: ::..::....: :::.: ::: :::: .:..: ::.
NP_569 DLMRSRLDTEVANLSVIMEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPT
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE1 GGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQP
:..: ::. : :: :: : .: : ::: :::: : .: : :::.:: : :.:
NP_569 GNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGS-----P-GKP
470 480 490 500 510
540 550 560 570 580 590
pF1KE1 GPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPP
::.: : ::: ::::. : :::: ::. : :. :. :. ::.: ::. : ::.:::
NP_569 GPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPK
520 530 540 550 560 570
600
pF1KE1 GPPGSQSFY
::::
NP_569 GPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCED
580 590 600 610 620 630
>>XP_011524043 (OMIM: 607621) PREDICTED: collectin-12 is (725 aa)
initn: 1835 init1: 890 opt: 1238 Z-score: 561.7 bits: 114.3 E(85289): 1.5e-24
Smith-Waterman score: 1238; 35.6% identity (67.2% similar) in 570 aa overlap (35-601:2-564)
10 20 30 40 50 60
pF1KE1 SAGGDGDALCVTEEDLAGDDEDMPTFPCTQKG-RPGPRCSRCQKNLSLHTSVRILYLFLA
:: . : .:..:..: .:. :. .::.. :
XP_011 MKGIQEGTQCTKCKNNWALKFSIILLYILCA
10 20 30
70 80 90 100 110 120
pF1KE1 LLLVAVAVLASLVFRKVDSLSEDISLTQSIYDKKLVLMQKNLQGL-DPKALNNCSFCHEA
:: ..::.:. : .:.:... . ... :: ::. ....:. : : . . : :
XP_011 LLTITVAILGYKVVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSEL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 GQLGPEIRKLQEELEGIQKLLLAQEVQLDQTLQAQEVLSTTSRQISQEMGSCSFSIHQVN
. . .: :...:. : . .. :.. . ..: . :... . . :: : ::
XP_011 STFRSDILDLRQQLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 QSLGLFLAQVRGWQATTAGLDLSLKDLTQECYDVKAAVHQINFTVGQTSEWIHGIQRKTD
..: . . : . : :. :. .:.. : ....:.: : . : ..::..:
XP_011 KTLQAYNGYVTNLQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVD
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 EETLTLQKIVTDWQNYTRLFSGLRTTSTKTGEAVKNIQATLGASSQRISQ-NSESMHDLV
. . ..:.: .:.:: ..: . . : :...: ::.:... ... :.....:.
XP_011 DTSQAIQRIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQ-TLAANNSALAKANNDTLEDMN
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 LQVMGLQLQLDNISSFLDDHEENMHDLQYHTHYAQNRTVERFESLEGRMASHEIEIGTIF
:. .. :..::... . .:.:..::: . :.:::. .:..:: :. : .: .:.
XP_011 SQLNSFTGQMENITTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNII
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 TNINATDNHVHSMLKYLDDVRLSCTLGFHTHAEELYYLNKSVSIMLGTTDLLRERFSLLS
.::. : .:.... . :..:: .:: . :...: ::.... . . :: . .:.
XP_011 SNISYTAHHLRTLTSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMR
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 ARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRG
.::: .: :::.:.:::: ::..::....: :::.: ::: :::: .:..: ::.:..:
XP_011 SRLDTEVANLSVIMEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 PKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKG
::. : :: :: : .: : ::: :::: : .: : :::.:: : :.:::.:
XP_011 QKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGS-----P-GKPGPQG
460 470 480 490 500
550 560 570 580 590 600
pF1KE1 DIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPG
. : ::: ::::. : :::: ::. : :. :. :. ::.: ::. : ::.::: ::::
XP_011 SSGDPGPPGPPGKEGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPG
510 520 530 540 550 560
pF1KE1 SQSFY
XP_011 PPGPSGAVVPLALQNEPTPAPEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSH
570 580 590 600 610 620
>>XP_005257116 (OMIM: 114000,120150,130000,130060,166200 (1158 aa)
initn: 2004 init1: 532 opt: 559 Z-score: 265.5 bits: 60.1 E(85289): 4.7e-08
Smith-Waterman score: 559; 54.1% identity (65.1% similar) in 146 aa overlap (457-602:746-888)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
::::: :: : .:: : ::.: :: :
XP_005 GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV
720 730 740 750 760 770
490 500 510 520 530 540
pF1KE1 GSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP
:. :: :::::.:. ::.: :.:: : ::: ::.: : :.: :. ::.: ::
XP_005 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGP--PGSP-GEQGPSGASGPA
780 790 800 810 820 830
550 560 570 580 590 600
pF1KE1 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY
::.::::: : : .: :. : : :: :: : : : :::: :::::::..
XP_005 GPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDF
840 850 860 870 880 890
XP_005 SFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPART
900 910 920 930 940 950
>--
initn: 3819 init1: 512 opt: 520 Z-score: 248.7 bits: 57.0 E(85289): 4.1e-07
Smith-Waterman score: 529; 50.3% identity (58.6% similar) in 169 aa overlap (457-601:179-347)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
: :: ::::. : :. :: : .:: :.:
XP_005 PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP
150 160 170 180 190 200
490 500 510 520 530
pF1KE1 G---SLGPLGPQGPQGQPG------EAG-P--VGERGPVGP---RGFPGLKGSKGSFGTG
: . ::.::.:: : :: ::: : ::::: :: ::.:: : : :
XP_005 GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR
210 220 230 240 250 260
540 550 560 570 580
pF1KE1 GPRGQPGPKGDIGPPGPEGPPGSPGPSG------PQGKPGIAGKTGSPGQRGAMGPKGEP
: : : ::: :: ::.: ::::: .: :.: :: :. :.:: : : .::
XP_005 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGPAGERGEQ
270 280 290 300 310 320
590 600
pF1KE1 GIQGPPG---LPGPPGPPGSQSFY
: : :: :::: ::::
XP_005 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA
330 340 350 360 370 380
>--
initn: 2403 init1: 512 opt: 520 Z-score: 248.7 bits: 57.0 E(85289): 4.1e-07
Smith-Waterman score: 525; 47.4% identity (59.1% similar) in 171 aa overlap (440-601:411-581)
410 420 430 440 450 460
pF1KE1 TDLLRERFSLLSARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKG
: .: . :... ::: : :::.: .:
XP_005 VQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG
390 400 410 420 430 440
470 480 490 500 510 520
pF1KE1 DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---EAGPVGERGPVGPRGFPGLKGSKG
: : :: :. : : : ::.:: :: : :: :.:: : ::.: :: :: .: :
XP_005 DAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG
450 460 470 480 490 500
530 540 550 560 570 580
pF1KE1 SFGTGG---P---RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMG
: .: : :::: ::. : : .: : :::.:: : :: :..:.:: .:: :
XP_005 PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG
510 520 530 540 550 560
590 600
pF1KE1 PKGEPGIQGPPGLPGPPGPPGSQSFY
: :: : :: : ::::
XP_005 SAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG
570 580 590 600 610 620
>--
initn: 2575 init1: 475 opt: 479 Z-score: 230.9 bits: 53.7 E(85289): 4e-06
Smith-Waterman score: 522; 47.5% identity (57.4% similar) in 162 aa overlap (457-600:584-745)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
: ::::: : : : ::: : :: : :
XP_005 GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP
560 570 580 590 600 610
490 500 510 520 530
pF1KE1 GSLGPLGPQGP---QGQPGEAGPVGERGPVGPRG---------FPGLKGSKGSFGTGGPR
: .:: :: :: .:.:: ::.: : ::.: .:: .: .: : ::
XP_005 GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS
620 630 640 650 660 670
540 550 560 570 580
pF1KE1 GQPGPKG------DIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ
:.:: .: . ::::: :::: :: : .:. : : ::::. :. : ::. :
XP_005 GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET
680 690 700 710 720 730
590 600
pF1KE1 GPPGLPGPPGPPGSQSFY
:: : :: :: :
XP_005 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET
740 750 760 770 780 790
>>XP_005257115 (OMIM: 114000,120150,130000,130060,166200 (1374 aa)
initn: 2450 init1: 532 opt: 559 Z-score: 264.7 bits: 60.2 E(85289): 5.3e-08
Smith-Waterman score: 559; 54.1% identity (65.1% similar) in 146 aa overlap (457-602:962-1104)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
::::: :: : .:: : ::.: :: :
XP_005 GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV
940 950 960 970 980 990
490 500 510 520 530 540
pF1KE1 GSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP
:. :: :::::.:. ::.: :.:: : ::: ::.: : :.: :. ::.: ::
XP_005 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGP--PGSP-GEQGPSGASGPA
1000 1010 1020 1030 1040
550 560 570 580 590 600
pF1KE1 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY
::.::::: : : .: :. : : :: :: : : : :::: :::::::..
XP_005 GPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDF
1050 1060 1070 1080 1090 1100
XP_005 SFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPART
1110 1120 1130 1140 1150 1160
>--
initn: 2863 init1: 509 opt: 535 Z-score: 254.3 bits: 58.3 E(85289): 2e-07
Smith-Waterman score: 535; 48.7% identity (61.7% similar) in 154 aa overlap (456-603:421-574)
430 440 450 460 470 480
pF1KE1 LNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD
.: :::::.: .:. :. : : : ::.
XP_005 DGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE
400 410 420 430 440 450
490 500 510 520 530
pF1KE1 PGSLGPLGPQGPQGQPG------EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP
:: .: :: :: :. : : ::.: :: : :: :: .: :. :..::.: :
XP_005 PGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE1 KGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGP
.:. :: ::.: :: : : : :: : :::::. : : : :: : : ::::::
XP_005 RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP
520 530 540 550 560 570
600
pF1KE1 PGSQSFY
::..
XP_005 PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE
580 590 600 610 620 630
>--
initn: 1944 init1: 517 opt: 517 Z-score: 246.5 bits: 56.9 E(85289): 5.4e-07
Smith-Waterman score: 531; 50.6% identity (58.4% similar) in 166 aa overlap (457-601:179-344)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
: :: ::::. : :. :: : .:: :.:
XP_005 PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP
150 160 170 180 190 200
490 500 510 520 530
pF1KE1 G---SLGPLGPQGPQGQPG------EAG-P--VGERGPVGP---RGFPGLKGSKGSFGTG
: . ::.::.:: : :: ::: : ::::: :: ::.:: : : :
XP_005 GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR
210 220 230 240 250 260
540 550 560 570 580
pF1KE1 GPRGQPGPKGDIGPPGPEGPPGSPGPSG------PQGKPGIAGKTGSPGQRGAMGPKGEP
: : : ::: :: ::.: ::::: .: :.: :: :. :.:: :: : :
XP_005 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT
270 280 290 300 310 320
590 600
pF1KE1 GIQGPPGLPGPPGPPGSQSFY
: :::: :: ::::
XP_005 GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP
330 340 350 360 370 380
>--
initn: 2834 init1: 499 opt: 512 Z-score: 244.4 bits: 56.5 E(85289): 7.1e-07
Smith-Waterman score: 526; 46.9% identity (58.7% similar) in 179 aa overlap (440-603:717-895)
410 420 430 440 450 460
pF1KE1 TDLLRERFSLLSARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKG
: .: . :... ::: : :::.: .:
XP_005 VQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG
690 700 710 720 730 740
470 480 490 500 510 520
pF1KE1 DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---EAGPVGERGPVGPRGFPGLKGSKG
: : :: :. : : : ::.:: :: : :: :.:: : ::.: :: :: .: :
XP_005 DAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG
750 760 770 780 790 800
530 540 550 560 570 580
pF1KE1 SFGTGG---P---RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMG
: .: : :::: ::. : : .: : :::.:: : :: :..:.:: .:: :
XP_005 PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG
810 820 830 840 850 860
590 600
pF1KE1 PKGEPGIQGPPGLPG---PPGP---PGSQSFY
: :: : :: : :::: ::.:
XP_005 SAGPPGATGFPGAAGRVGPPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREG
870 880 890 900 910 920
>--
initn: 417 init1: 417 opt: 420 Z-score: 204.5 bits: 49.1 E(85289): 0.00012
Smith-Waterman score: 420; 45.5% identity (56.6% similar) in 145 aa overlap (457-598:578-716)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
:. : :::.: :. : .: :: : :
XP_005 GPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE---PGKAGERGVPGPP
550 560 570 580 590 600
490 500 510 520 530 540
pF1KE1 GSLGPLGPQGP---QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI
:..:: : .: :: :: :::.:::: :: : ::..: : .:: :. : :.
XP_005 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGP---AGPPGEAGKPGEQ
610 620 630 640 650 660
550 560 570 580 590 600
pF1KE1 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ
: :: : :: : : .: :: : : :: : : .: :: .: : : ::
XP_005 GVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ
670 680 690 700 710 720
pF1KE1 SFY
XP_005 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK
730 740 750 760 770 780
>>XP_011522643 (OMIM: 114000,120150,130000,130060,166200 (1398 aa)
initn: 2477 init1: 532 opt: 559 Z-score: 264.6 bits: 60.2 E(85289): 5.3e-08
Smith-Waterman score: 559; 54.1% identity (65.1% similar) in 146 aa overlap (457-602:986-1128)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
::::: :: : .:: : ::.: :: :
XP_011 GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV
960 970 980 990 1000 1010
490 500 510 520 530 540
pF1KE1 GSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDIGPP
:. :: :::::.:. ::.: :.:: : ::: ::.: : :.: :. ::.: ::
XP_011 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGP--PGSP-GEQGPSGASGPA
1020 1030 1040 1050 1060 1070
550 560 570 580 590 600
pF1KE1 GPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQSFY
::.::::: : : .: :. : : :: :: : : : :::: :::::::..
XP_011 GPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDF
1080 1090 1100 1110 1120 1130
XP_011 SFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPART
1140 1150 1160 1170 1180 1190
>--
initn: 3371 init1: 512 opt: 520 Z-score: 247.8 bits: 57.1 E(85289): 4.6e-07
Smith-Waterman score: 535; 48.7% identity (61.7% similar) in 154 aa overlap (456-603:355-508)
430 440 450 460 470 480
pF1KE1 LNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGD
.: :::::.: .:. :. : : : ::.
XP_011 DGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE
330 340 350 360 370 380
490 500 510 520 530
pF1KE1 PGSLGPLGPQGPQGQPG------EAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGP
:: .: :: :: :. : : ::.: :: : :: :: .: :. :..::.: :
XP_011 PGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE
390 400 410 420 430 440
540 550 560 570 580 590
pF1KE1 KGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGP
.:. :: ::.: :: : : : :: : :::::. : : : :: : : ::::::
XP_011 RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP
450 460 470 480 490 500
600
pF1KE1 PGSQSFY
::..
XP_011 PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE
510 520 530 540 550 560
>--
initn: 2886 init1: 512 opt: 520 Z-score: 247.8 bits: 57.1 E(85289): 4.6e-07
Smith-Waterman score: 525; 47.4% identity (59.1% similar) in 171 aa overlap (440-601:651-821)
410 420 430 440 450 460
pF1KE1 TDLLRERFSLLSARLDLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKG
: .: . :... ::: : :::.: .:
XP_011 VQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG
630 640 650 660 670 680
470 480 490 500 510 520
pF1KE1 DMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPG---EAGPVGERGPVGPRGFPGLKGSKG
: : :: :. : : : ::.:: :: : :: :.:: : ::.: :: :: .: :
XP_011 DAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG
690 700 710 720 730 740
530 540 550 560 570 580
pF1KE1 SFGTGG---P---RGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMG
: .: : :::: ::. : : .: : :::.:: : :: :..:.:: .:: :
XP_011 PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARG
750 760 770 780 790 800
590 600
pF1KE1 PKGEPGIQGPPGLPGPPGPPGSQSFY
: :: : :: : ::::
XP_011 SAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG
810 820 830 840 850 860
>--
initn: 1806 init1: 496 opt: 518 Z-score: 246.9 bits: 57.0 E(85289): 5.2e-07
Smith-Waterman score: 526; 48.5% identity (60.0% similar) in 165 aa overlap (455-601:189-353)
430 440 450 460 470
pF1KE1 DLNVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKG------DMGVKGPVG
: : :: :::.::.: . :..::.:
XP_011 FAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMG
160 170 180 190 200 210
480 490 500 510 520
pF1KE1 GRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVG-P-----------RGFPGLKGSKG
::: : ::. : : : :.::: :: : .: : : ::: :: :.::
XP_011 PRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKG
220 230 240 250 260 270
530 540 550 560 570 580
pF1KE1 SFGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPG
. : .::.:.:: :. : :: :: : :: : : :: ::. :. :: :: : .: ::
XP_011 DAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGNPGADGQPGAKGANGAPG
280 290 300 310 320 330
590 600
pF1KE1 IQGPPGLPGPPGPPGSQSFY
: : ::.:: :: :
XP_011 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG
340 350 360 370 380 390
>--
initn: 2575 init1: 475 opt: 479 Z-score: 230.0 bits: 53.8 E(85289): 4.5e-06
Smith-Waterman score: 522; 47.5% identity (57.4% similar) in 162 aa overlap (457-600:824-985)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
: ::::: : : : ::: : :: : :
XP_011 GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP
800 810 820 830 840 850
490 500 510 520 530
pF1KE1 GSLGPLGPQGP---QGQPGEAGPVGERGPVGPRG---------FPGLKGSKGSFGTGGPR
: .:: :: :: .:.:: ::.: : ::.: .:: .: .: : ::
XP_011 GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS
860 870 880 890 900 910
540 550 560 570 580
pF1KE1 GQPGPKG------DIGPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQ
:.:: .: . ::::: :::: :: : .:. : : ::::. :. : ::. :
XP_011 GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET
920 930 940 950 960 970
590 600
pF1KE1 GPPGLPGPPGPPGSQSFY
:: : :: :: :
XP_011 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET
980 990 1000 1010 1020 1030
>--
initn: 417 init1: 417 opt: 420 Z-score: 204.5 bits: 49.1 E(85289): 0.00012
Smith-Waterman score: 420; 45.5% identity (56.6% similar) in 145 aa overlap (457-598:512-650)
430 440 450 460 470 480
pF1KE1 NVRNLSMIVEEMKAVDTQHGEILRNVTILRGAPGPPGPRGFKGDMGVKGPVGGRGPKGDP
:. : :::.: :. : .: :: : :
XP_011 GPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE---PGKAGERGVPGPP
490 500 510 520 530
490 500 510 520 530 540
pF1KE1 GSLGPLGPQGP---QGQPGEAGPVGERGPVGPRGFPGLKGSKGSFGTGGPRGQPGPKGDI
:..:: : .: :: :: :::.:::: :: : ::..: : .:: :. : :.
XP_011 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGP---AGPPGEAGKPGEQ
540 550 560 570 580 590
550 560 570 580 590 600
pF1KE1 GPPGPEGPPGSPGPSGPQGKPGIAGKTGSPGQRGAMGPKGEPGIQGPPGLPGPPGPPGSQ
: :: : :: : : .: :: : : :: : : .: :: .: : : ::
XP_011 GVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ
600 610 620 630 640 650
pF1KE1 SFY
XP_011 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK
660 670 680 690 700 710
606 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:11:46 2016 done: Sat Nov 5 19:11:48 2016
Total Scan time: 12.760 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]