Result of FASTA (omim) for
pFN21AE1096
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1096, 366 aa
1>>>pF1KE1096 366 - 366 aa - 366 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8519+/-0.000451; mu= 18.8618+/- 0.028
mean_var=90.2761+/-23.853, 0's: 0 Z-trim(110.3): 706 B-trim: 1891 in 2/47
Lambda= 0.134986
statistics sampled from 17800 (18666) to 17800 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.219), width: 16
Scan time: 7.120
The best scores are: opt bits E(85289)
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 2440 486.0 5.8e-137
NP_004113 (OMIM: 601898) growth hormone secretagog ( 289) 1781 357.5 2.1e-98
NP_001498 (OMIM: 602885) motilin receptor [Homo sa ( 412) 645 136.5 1.1e-31
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 586 125.0 3.1e-28
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 496 107.4 5.5e-23
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 496 107.5 5.7e-23
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 483 104.8 2.8e-22
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 448 98.1 3.9e-20
XP_011527129 (OMIM: 162651) PREDICTED: neurotensin ( 336) 440 96.5 9.7e-20
NP_002522 (OMIM: 162651) neurotensin receptor type ( 418) 440 96.6 1.1e-19
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 434 95.4 2.4e-19
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 432 94.9 3e-19
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 432 94.9 3e-19
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 432 94.9 3e-19
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 432 94.9 3e-19
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 432 95.0 3.1e-19
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 432 95.0 3.1e-19
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 432 95.0 3.1e-19
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 432 95.0 3.2e-19
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 429 94.4 4.7e-19
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 429 94.4 4.7e-19
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 429 94.4 4.8e-19
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 429 94.4 4.8e-19
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 429 94.4 4.8e-19
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 429 94.4 4.8e-19
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 429 94.4 4.9e-19
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 429 94.4 4.9e-19
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 429 94.4 5e-19
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 429 94.4 5.1e-19
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 429 94.5 5.5e-19
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 429 94.5 5.5e-19
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 426 93.8 6.8e-19
XP_011508791 (OMIM: 604153) PREDICTED: neuromedin- ( 313) 425 93.5 7e-19
XP_006712259 (OMIM: 604153) PREDICTED: neuromedin- ( 333) 425 93.5 7.3e-19
XP_006712258 (OMIM: 604153) PREDICTED: neuromedin- ( 370) 425 93.6 7.8e-19
XP_011508790 (OMIM: 604153) PREDICTED: neuromedin- ( 376) 425 93.6 7.9e-19
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 425 93.6 8.3e-19
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 425 93.6 8.6e-19
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 407 90.1 8.9e-18
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 406 89.9 1e-17
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 403 89.4 1.7e-17
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 400 88.7 2.3e-17
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 400 88.7 2.3e-17
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 396 88.0 4.2e-17
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 396 88.0 4.2e-17
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 396 88.0 4.2e-17
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 396 88.0 4.2e-17
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 396 88.0 4.2e-17
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 396 88.0 4.2e-17
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 396 88.0 4.2e-17
>>NP_940799 (OMIM: 601898) growth hormone secretagogue r (366 aa)
initn: 2440 init1: 2440 opt: 2440 Z-score: 2579.9 bits: 486.0 E(85289): 5.8e-137
Smith-Waterman score: 2440; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KE1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
310 320 330 340 350 360
pF1KE1 ESSINT
::::::
NP_940 ESSINT
>>NP_004113 (OMIM: 601898) growth hormone secretagogue r (289 aa)
initn: 1781 init1: 1781 opt: 1781 Z-score: 1887.5 bits: 357.5 E(85289): 2.1e-98
Smith-Waterman score: 1781; 100.0% identity (100.0% similar) in 265 aa overlap (1-265:1-265)
10 20 30 40 50 60
pF1KE1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
:::::::::::::::::::::::::
NP_004 RRRRGDAVVGASLRDQNHKQTVKMLGGSQRALRLSLAGPILSLCLLPSL
250 260 270 280
>>NP_001498 (OMIM: 602885) motilin receptor [Homo sapien (412 aa)
initn: 1136 init1: 637 opt: 645 Z-score: 690.1 bits: 136.5 E(85289): 1.1e-31
Smith-Waterman score: 1072; 47.5% identity (70.2% similar) in 379 aa overlap (2-338:5-370)
10 20 30 40 50
pF1KE1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVG
::.. . : . . : : : : .. . :: :. :::.:. :::::
NP_001 MGSPWNGSDGPEGA-----REPPWPALPPCD---ERRCSPFPLGALVPVTAVCLCLFVVG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 IAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCK
..::..:.....:.:..::::::::.::: :::::.: .:.:: :::. ::: :: :::.
NP_001 VSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGP
: .:.:.:::::.: .::::::::.::: ::::.:.::. ::. .: :.::::. ::::
NP_001 LSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGP
120 130 140 150 160 170
180 190
pF1KE1 IFVLVGVEHE---------NGT-----DP-------WDTN--------------------
.. :::::.. ::: .: : .
NP_001 FLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFS
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE1 -ECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRD
::::. .. : : ::.::.. .:::: .::..::.::::.:: :: .:: :.
NP_001 RECRPSP--AQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRE
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE1 QNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLS
..:.:::..: :::.:::.::::::::: .. .. . .. .::: :.:.. :::::
NP_001 RGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDS---RMMYFSQYFNIVALQLFYLS
300 310 320 330 340
320 330 340 350 360
pF1KE1 AAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
:.:::::::..:::::.:.:.::
NP_001 ASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSAN
350 360 370 380 390 400
>>NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [Homo (415 aa)
initn: 447 init1: 209 opt: 586 Z-score: 628.0 bits: 125.0 E(85289): 3.1e-28
Smith-Waterman score: 586; 34.2% identity (66.8% similar) in 295 aa overlap (46-333:48-337)
20 30 40 50 60 70
pF1KE1 LADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELR
:... : .::::. ::.:. ::. . . ..
NP_064 LEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMK
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE1 TTTNLYLSSMAFSDLLIFLC-MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTI
: :: :: :.: ::::..: :::.. ..:. :. :: . : . . :. .:..:.:
NP_064 TPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSI
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE1 TALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHE---NGTD
:..::::: :: :.:::. :. :. .. ..:. . . : . :.. . ::.
NP_064 TTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSL
140 150 160 170 180 190
200 210 220 230 240
pF1KE1 PWDTNECRPTEFAVRSG-LLTVMVWVSS-IFFFLPVFCLTVLYSLIGRKLWRRRRGDAVV
. : ... . . .. :.: .:..::. ..::: :.. .: . . .:
NP_064 VPGSATCT----VIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADE
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE1 G-ASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVS
: :... .:.. ::: :.:..: .:: :::. : .:: : : .: . . ..::
NP_064 GNANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFS-FVEEWSESLAAVFNLVHVVS
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 FVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
:.::::.:.:::.::..:.....:
NP_064 GVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPAQRNIFLTECHFV
320 330 340 350 360 370
>>NP_000903 (OMIM: 165196) kappa-type opioid receptor is (380 aa)
initn: 436 init1: 172 opt: 496 Z-score: 533.7 bits: 107.4 E(85289): 5.5e-23
Smith-Waterman score: 504; 27.8% identity (63.7% similar) in 331 aa overlap (21-346:33-351)
10 20 30 40
pF1KE1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGV----
: .: : :.: :: :: . ..
NP_000 SPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVII
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 TATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQY
::. ..::::..:: :.:.:. :. ...:.::.:. ..:..: :. ::.. . .. .
NP_000 TAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQST-VYLM
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 RPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFV
: :::.:::. .. .....:.: .::.::.:.: :..: : ..:.. .
NP_000 NSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINIC
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 IWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTE-FAVRSGLLTVMVWVSSIFFFLPV
:: .. . .:: :.. .. .: . . : . .. . .. . :.. . : .::
NP_000 IWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFA--FVIPV
190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYL
. . : :.:. .: : . :. .:.: .. .... ::: .:..:: :.:. ..
NP_000 LIIIVCYTLMILRLKSVR---LLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHI--FI
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 FSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQ
. ... : : .:.: ..: : ....::::: ....... :: . : :...
NP_000 LVEALGSTSHSTAALSSY--YFCIALGYTNSSLNPILYAFLDENFK-RCFRDFCF-PLKM
300 310 320 330 340 350
350 360
pF1KE1 RKLSTLKDESSRAWTESSINT
:
NP_000 RMERQSTSRVRNTVQDPAYLRDIDGMNKPV
360 370 380
>>NP_001305426 (OMIM: 165196) kappa-type opioid receptor (409 aa)
initn: 436 init1: 172 opt: 496 Z-score: 533.3 bits: 107.5 E(85289): 5.7e-23
Smith-Waterman score: 504; 27.8% identity (63.7% similar) in 331 aa overlap (21-346:33-351)
10 20 30 40
pF1KE1 MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGV----
: .: : :.: :: :: . ..
NP_001 SPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVII
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 TATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQY
::. ..::::..:: :.:.:. :. ...:.::.:. ..:..: :. ::.. . .. .
NP_001 TAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQST-VYLM
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 RPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFV
: :::.:::. .. .....:.: .::.::.:.: :..: : ..:.. .
NP_001 NSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINIC
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 IWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTE-FAVRSGLLTVMVWVSSIFFFLPV
:: .. . .:: :.. .. .: . . : . .. . .. . :.. . : .::
NP_001 IWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFA--FVIPV
190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYL
. . : :.:. .: : . :. .:.: .. .... ::: .:..:: :.:. ..
NP_001 LIIIVCYTLMILRLKSVR---LLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHI--FI
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 FSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQ
. ... : : .:.: ..: : ....::::: ....... :: . : :...
NP_001 LVEALGSTSHSTAALSSY--YFCIALGYTNSSLNPILYAFLDENFK-RCFRDFCF-PLKM
300 310 320 330 340 350
350 360
pF1KE1 RKLSTLKDESSRAWTESSINT
:
NP_001 RMERQSTSRVRNTVQDPAYLRDIDGMNKPVXLVVEMSSYSSSGREEFNDLGLTQITTAV
360 370 380 390 400
>>XP_011535972 (OMIM: 605108) PREDICTED: neuromedin-U re (321 aa)
initn: 343 init1: 209 opt: 483 Z-score: 520.9 bits: 104.8 E(85289): 2.8e-22
Smith-Waterman score: 483; 32.7% identity (63.6% similar) in 269 aa overlap (46-308:48-312)
20 30 40 50 60 70
pF1KE1 LADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELR
:... : .::::. ::.:. ::. . . ..
XP_011 LEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMK
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE1 TTTNLYLSSMAFSDLLIFLC-MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTI
: :: :: :.: ::::..: :::.. ..:. :. :: . : . . :. .:..:.:
XP_011 TPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSI
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE1 TALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHE---NGTD
:..::::: :: :.:::. :. :. .. ..:. . . : . :.. . ::.
XP_011 TTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSL
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE1 PWDTNECRPTEFAVRSGLLTVMVWVSS-IFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVG
. : . . . .. :.: .:..::. ..::: :.. .: . . .: :
XP_011 VPGSATCTVIKPMW---IYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEG
200 210 220 230 240 250
260 270 280 290 300
pF1KE1 -ASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSF
:... .:.. ::: :.:..: .:: :::. : .:: : : .: . . ..::
XP_011 NANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFS-FVEEWSESLAAVFNLVHVVSG
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 VLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
XP_011 KTLAGFGA
320
>>NP_937822 (OMIM: 606925) pyroglutamylated RFamide pept (431 aa)
initn: 340 init1: 281 opt: 448 Z-score: 482.5 bits: 98.1 E(85289): 3.9e-20
Smith-Waterman score: 449; 30.1% identity (64.5% similar) in 299 aa overlap (49-335:51-344)
20 30 40 50 60 70
pF1KE1 LDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTT
: : .:.... :: :.. ::.: . .::.:
NP_937 TREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVT
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE1 NLYLSSMAFSDLLI-FLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITAL
:... :.:.::::: :.:.:. ... . : : ..::. ::. . . . .::.: .
NP_937 NIFICSLALSDLLITFFCIPVTMLQNISDN-WLGGAFICKMVPFVQSTAVVTEILTMTCI
90 100 110 120 130
140 150 160 170 180 190
pF1KE1 SVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNE
.:::. .. :.. : :. :. .. :.: :: ..:.. . .: . .
NP_937 AVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHI
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE1 CRPTEFA--VRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW-RRRRGDAVVGASLR
: :.. :.. . :... : :.:.::.. . .::: :: .:: ..: ::. : ...
NP_937 CCLEEWTSPVHQKIYTTFILV--ILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIH
200 210 220 230 240 250
260 270 280 290 300
pF1KE1 DQN-------HKQTVKMLAVVVFAFILCWLPFHVGRYLFSKS-FEPGSLEIAQISQYCNL
.. .:..: :...:: : .:: :::: .... : :: ... :.. .
NP_937 GKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVT-IKMIFAI
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 VSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
:... : : :::.: .:..... :.
NP_937 VQIIGFSNSIC-NPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAK
320 330 340 350 360 370
>>XP_011527129 (OMIM: 162651) PREDICTED: neurotensin rec (336 aa)
initn: 472 init1: 252 opt: 440 Z-score: 475.4 bits: 96.5 E(85289): 9.7e-20
Smith-Waterman score: 520; 35.8% identity (69.4% similar) in 265 aa overlap (46-286:66-326)
20 30 40 50 60 70
pF1KE1 LADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSR---FR
:::. .:::::: .:: .: ....: ..
XP_011 GNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQ
40 50 60 70 80 90
80 90 100 110 120 130
pF1KE1 ELRTTTNLYLSSMAFSDLL-IFLCMPLDLVR-LWQYRPWNFGDLLCKLFQFVSESCTYAT
:..:.. .:.:.:.:::: ..: ::..: .: ..:: ::: :. . :. ..:::::
XP_011 SLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYAT
100 110 120 130 140 150
140 150 160 170 180 190
pF1KE1 VLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGT
.:....::::::.::: :..::......:.: : .:: .. : :.. .: :.. ..
XP_011 ALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMG-EQNRSA
160 170 180 190 200 210
200 210 220 230 240
pF1KE1 DPWDTNE--CRPTEFAVRSGLLTVMVWVSSIF-FFLPVFCLTVLYSLIGRKLWRRRRGDA
: .. : :: .... . :.. :.... :..:. ..:: ..:. :: : :
XP_011 DGQHAGGLVCTPT---IHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAA
220 230 240 250 260 270
250 260 270 280 290
pF1KE1 ------VVGA-----SL-----RDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFE
.::. :. : : .. :..: .::.::..::::.:: : .:
XP_011 EQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISD
280 290 300 310 320 330
300 310 320 330 340 350
pF1KE1 PGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTL
XP_011 EQWTP
>>NP_002522 (OMIM: 162651) neurotensin receptor type 1 [ (418 aa)
initn: 521 init1: 252 opt: 440 Z-score: 474.3 bits: 96.6 E(85289): 1.1e-19
Smith-Waterman score: 604; 36.0% identity (69.5% similar) in 311 aa overlap (46-331:66-372)
20 30 40 50 60 70
pF1KE1 LADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSR---FR
:::. .:::::: .:: .: ....: ..
NP_002 GNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQ
40 50 60 70 80 90
80 90 100 110 120 130
pF1KE1 ELRTTTNLYLSSMAFSDLL-IFLCMPLDLVR-LWQYRPWNFGDLLCKLFQFVSESCTYAT
:..:.. .:.:.:.:::: ..: ::..: .: ..:: ::: :. . :. ..:::::
NP_002 SLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYAT
100 110 120 130 140 150
140 150 160 170 180 190
pF1KE1 VLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGT
.:....::::::.::: :..::......:.: : .:: .. : :.. .: :.. ..
NP_002 ALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMG-EQNRSA
160 170 180 190 200 210
200 210 220 230 240
pF1KE1 DPWDTNE--CRPTEFAVRSGLLTVMVWVSSIF-FFLPVFCLTVLYSLIGRKLWRRRRGDA
: .. : :: .... . :.. :.... :..:. ..:: ..:. :: : :
NP_002 DGQHAGGLVCTPT---IHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAA
220 230 240 250 260 270
250 260 270 280 290
pF1KE1 ------VVGA-----SL-----RDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSK-SF
.::. :. : : .. :..: .::.::..::::.:: : .: :
NP_002 EQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISD
280 290 300 310 320 330
300 310 320 330 340 350
pF1KE1 EPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLST
: . . .. .: .:. .:::.:..:::::::..: ..:
NP_002 EQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRK
340 350 360 370 380 390
360
pF1KE1 LKDESSRAWTESSINT
NP_002 RPAFSRKADSVSSNHTLSSNATRETLY
400 410
366 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:09:30 2016 done: Sat Nov 5 19:09:32 2016
Total Scan time: 7.120 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]