Result of FASTA (ccds) for
pFN21AB4086
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4086, 520 aa
1>>>pF1KB4086 520 - 520 aa - 520 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9012+/-0.00103; mu= 14.4133+/- 0.062
mean_var=60.7611+/-11.784, 0's: 0 Z-trim(102.9): 23 B-trim: 2 in 1/47
Lambda= 0.164536
statistics sampled from 7130 (7138) to 7130 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.59), E-opt: 0.2 (0.219), width: 16
Scan time: 3.060
The best scores are: opt bits E(32554)
CCDS34154.1 HMGCS1 gene_id:3157|Hs108|chr5 ( 520) 3456 829.3 0
CCDS905.1 HMGCS2 gene_id:3158|Hs108|chr1 ( 508) 2218 535.4 5.9e-152
CCDS53353.1 HMGCS2 gene_id:3158|Hs108|chr1 ( 466) 1233 301.6 1.3e-81
>>CCDS34154.1 HMGCS1 gene_id:3157|Hs108|chr5 (520 aa)
initn: 3456 init1: 3456 opt: 3456 Z-score: 4429.6 bits: 829.3 E(32554): 0
Smith-Waterman score: 3456; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KB4 MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 IGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 HAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 HAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FGDVKLEDTYFDRDVEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 FGDVKLEDTYFDRDVEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 SPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 SPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 DVFAENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRPTPNDDTLDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DVFAENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRPTPNDDTLDEG
430 440 450 460 470 480
490 500 510 520
pF1KB4 VGLVHSNIATEHIPSPAKKVPRLPATAAEPEAAVISNGEH
::::::::::::::::::::::::::::::::::::::::
CCDS34 VGLVHSNIATEHIPSPAKKVPRLPATAAEPEAAVISNGEH
490 500 510 520
>>CCDS905.1 HMGCS2 gene_id:3158|Hs108|chr1 (508 aa)
initn: 2218 init1: 2218 opt: 2218 Z-score: 2841.6 bits: 535.4 E(32554): 5.9e-152
Smith-Waterman score: 2218; 67.5% identity (89.7% similar) in 467 aa overlap (4-470:41-507)
10 20 30
pF1KB4 MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQ
..:: :::::::.:::.:::.:::::
CCDS90 ILQLTRAVQETSLTPARLLPVAHQRFSTASAVPLAKTDTWPKDVGILALEVYFPAQYVDQ
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB4 AELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVG
..::::..:.:::::.::::..::::. .:::::::.:::: :::: .: .: .::::::
CCDS90 TDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERIQLPWDSVGRLEVG
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB4 TETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYA
:::::::::.::: ::.::..::::::::::::::::::::..:::.::.::::::::::
CCDS90 TETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYA
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB4 LVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEY
.:: :::::: .::::::::.::::.::::.::: .:::::::::...::::::.. :::
CCDS90 MVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB4 PIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQK
::::::::::::: ::::::. : :::. ::.. :.:. :::.:. .::::.:.::.:::
CCDS90 PIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQK
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB4 SLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFSQKTKA
::::...::::. .. ..:.:.:::::: .:::::: ..:..::..:::...:..::::
CCDS90 SLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB4 SLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDAT
:: .:..::::::::.:: :::.:...: :.:::.:::.:::::::::...:..:.:::.
CCDS90 SLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSQDAA
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB4 PGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTHHLVNYIPQGSIDSLFEGTW
::: :::...: :: .:: :: :.:. :.: :. ::. .: ::. : :. .::: :::
CCDS90 PGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDTNSLFPGTW
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB4 YLVRVDEKHRRTYARRPTPNDDTLDEGVGLVHSNIATEHIPSPAKKVPRLPATAAEPEAA
:: ::::.::: :::::
CCDS90 YLERVDEQHRRKYARRPV
500
>>CCDS53353.1 HMGCS2 gene_id:3158|Hs108|chr1 (466 aa)
initn: 1233 init1: 1233 opt: 1233 Z-score: 1578.6 bits: 301.6 E(32554): 1.3e-81
Smith-Waterman score: 1899; 60.4% identity (81.4% similar) in 467 aa overlap (4-470:41-465)
10 20 30
pF1KB4 MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQ
..:: :::::::.:::.:::.:::::
CCDS53 ILQLTRAVQETSLTPARLLPVAHQRFSTASAVPLAKTDTWPKDVGILALEVYFPAQYVDQ
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB4 AELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVG
..::::..:.:::::.::::..::::. .:::::::.:::: :::: .: .: .::::::
CCDS53 TDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERIQLPWDSVGRLEVG
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB4 TETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYA
:::::::::.::: ::.::..::::::::::::::::::::..:::.::.:::::::
CCDS53 TETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDG---
140 150 160 170 180
160 170 180 190 200 210
pF1KB4 LVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEY
::::::...::::::.. :::
CCDS53 ---------------------------------------LRGTHMENVYDFYKPNLASEY
190 200
220 230 240 250 260 270
pF1KB4 PIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQK
::::::::::::: ::::::. : :::. ::.. :.:. :::.:. .::::.:.::.:::
CCDS53 PIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQK
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB4 SLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFSQKTKA
::::...::::. .. ..:.:.:::::: .:::::: ..:..::..:::...:..::::
CCDS53 SLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKA
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB4 SLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDAT
:: .:..::::::::.:: :::.:...: :.:::.:::.:::::::::...:..:.:::.
CCDS53 SLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSQDAA
330 340 350 360 370 380
400 410 420 430 440 450
pF1KB4 PGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTHHLVNYIPQGSIDSLFEGTW
::: :::...: :: .:: :: :.:. :.: :. ::. .: ::. : :. .::: :::
CCDS53 PGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDTNSLFPGTW
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB4 YLVRVDEKHRRTYARRPTPNDDTLDEGVGLVHSNIATEHIPSPAKKVPRLPATAAEPEAA
:: ::::.::: :::::
CCDS53 YLERVDEQHRRKYARRPV
450 460
520 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:36:12 2016 done: Sat Nov 5 05:36:13 2016
Total Scan time: 3.060 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]