Result of FASTA (ccds) for
pFN21AE0981
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0981, 580 aa
1>>>pF1KE0981 580 - 580 aa - 580 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9542+/-0.000952; mu= 14.7720+/- 0.057
mean_var=61.6206+/-12.792, 0's: 0 Z-trim(104.8): 33 B-trim: 264 in 1/49
Lambda= 0.163385
statistics sampled from 8083 (8095) to 8083 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.249), width: 16
Scan time: 3.430
The best scores are: opt bits E(32554)
CCDS34965.2 ADCK5 gene_id:203054|Hs108|chr8 ( 580) 3871 921.2 0
CCDS9869.1 ADCK1 gene_id:57143|Hs108|chr14 ( 523) 1038 253.5 5e-67
CCDS45144.1 ADCK1 gene_id:57143|Hs108|chr14 ( 455) 842 207.2 3.5e-53
CCDS1557.1 COQ8A gene_id:56997|Hs108|chr1 ( 647) 304 80.4 7.4e-15
CCDS12562.1 COQ8B gene_id:79934|Hs108|chr19 ( 544) 277 74.1 5.2e-13
CCDS46081.1 COQ8B gene_id:79934|Hs108|chr19 ( 503) 263 70.8 4.7e-12
>>CCDS34965.2 ADCK5 gene_id:203054|Hs108|chr8 (580 aa)
initn: 3871 init1: 3871 opt: 3871 Z-score: 4925.1 bits: 921.2 E(32554): 0
Smith-Waterman score: 3871; 99.8% identity (99.8% similar) in 580 aa overlap (1-580:1-580)
10 20 30 40 50 60
pF1KE0 MWRPVQLCHFHSALLHRRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPL
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
CCDS34 MWRPVQLCHFHSALLHSRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 EVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 VQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 LRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 LRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLK
490 500 510 520 530 540
550 560 570 580
pF1KE0 FEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET
::::::::::::::::::::::::::::::::::::::::
CCDS34 FEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET
550 560 570 580
>>CCDS9869.1 ADCK1 gene_id:57143|Hs108|chr14 (523 aa)
initn: 952 init1: 704 opt: 1038 Z-score: 1316.9 bits: 253.5 E(32554): 5e-67
Smith-Waterman score: 1043; 38.4% identity (65.1% similar) in 490 aa overlap (83-558:35-515)
60 70 80 90 100 110
pF1KE0 TAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGV
: : ::.. . :: :: . : :
CCDS98 ALKLASWTSMALAASGIYFYSNKYLDPNDFGAVRVGRAVATTAVISYDYLTSLKSVPYGS
10 20 30 40 50 60
120 130 140 150 160 170
pF1KE0 EENSPGYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLED
:: ::.. : : :.: : .: : ..:.:: : ....::: ::: ::.::..
CCDS98 EE----YLQLRSKVHLRSARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHS
70 80 90 100 110 120
180 190 200 210 220 230
pF1KE0 RALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYI
.: . ..::. ... ::. :.::: :: :...:::::::.: :::: .::::::.
CCDS98 QAPQSSMQEIRQVIREDLGKEIHDLFQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHP
130 140 150 160 170 180
240 250 260 270 280 290
pF1KE0 DLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCAREL
.: . . :: .:.:. :. . : : : :.... : .: :::: :::::::. .. :
CCDS98 KVRAQSSKDILLMEVLVLAVKQLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQML
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE0 AHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIF
:: .. :::.::: :..::: .: : .::: . .. . . :..:...: : ..:.::
CCDS98 RHFDFLKVPRIHWDLSTERVLLMEFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIF
250 260 270 280 290 300
360 370 380 390 400 410
pF1KE0 YTGFIHSDPHPGNVLVRKGPD-GKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAA
.::.: ::::::::::: : ::::.:::::::::.: :. : :.::...: :
CCDS98 VNGFVHCDPHPGNVLVRKHPGTGKAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWTDMKR
310 320 330 340 350 360
420 430 440 450 460
pF1KE0 MRAHAAALGVQD-YLLFAEMLMQRPV-RLGQLWGSHLLSREEAAYMVDMARERFEAVMAV
.. .. ::. : : ::: :: : ... .. .. : . . : . . . .
CCDS98 VKEYSQRLGAGDLYPLFACMLTARSWDSVNRGISQAPVTATEDLEIRNNAANYLPQISHL
370 380 390 400 410 420
470 480 490 500 510 520
pF1KE0 LRELPRPMLLVLRNINTVRAINVALG--APVDRYFLMAKRAVRGWSRLAGATYRGVYGTS
: ..:: :::.:.. . .:.:..::: : .. .. :.. .: : : .. :
CCDS98 LNHVPRQMLLILKTNDLLRGIEAALGTRASASSFLNMSRCCIR-----ALAEHKKKNTCS
430 440 450 460 470
530 540 550 560 570
pF1KE0 LLRHAKV-------VWEMLKFEVALRLETLAM--RLTALLARALVHLSLVPPAEELYQYL
..:.... .:.. :. ::.. : . :. ::.
CCDS98 FFRRTQISFSEAFNLWQINLHELILRVKGLKLADRVLALICWLFPAPL
480 490 500 510 520
580
pF1KE0 ET
>>CCDS45144.1 ADCK1 gene_id:57143|Hs108|chr14 (455 aa)
initn: 835 init1: 587 opt: 842 Z-score: 1068.2 bits: 207.2 E(32554): 3.5e-53
Smith-Waterman score: 847; 39.2% identity (66.7% similar) in 378 aa overlap (195-558:75-447)
170 180 190 200 210 220
pF1KE0 RTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTS
:.::: :: :...:::::::.: :::: .
CCDS45 TTAVISYDYLTSLKSVPYGSEEYLQLRSKIHDLFQSFDDTPLGTASLAQVHKAVLHDGRT
50 60 70 80 90 100
230 240 250 260 270 280
pF1KE0 VAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRN
::::::. .: . . :: .:.:. :. . : : : :.... : .: :::: :::::
CCDS45 VAVKVQHPKVRAQSSKDILLMEVLVLAVKQLFPEFEFMWLVDEAKKNLPLELDFLNEGRN
110 120 130 140 150 160
290 300 310 320 330 340
pF1KE0 AERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLI
::. .. : :: .. :::.::: :..::: .: : .::: . .. . . :..:...:
CCDS45 AEKVSQMLRHFDFLKVPRIHWDLSTERVLLMEFVDGGQVNDRDYMERNKIDVNEISRHLG
170 180 190 200 210 220
350 360 370 380 390 400
pF1KE0 KAFAEQIFYTGFIHSDPHPGNVLVRKGPD-GKAELVLLDHGLYQFLEEKDRAALCQLWRA
: ..:.:: .::.: ::::::::::: : ::::.:::::::::.: :. : :.::..
CCDS45 KMYSEMIFVNGFVHCDPHPGNVLVRKHPGTGKAEIVLLDHGLYQMLTEEFRLNYCHLWQS
230 240 250 260 270 280
410 420 430 440 450 460
pF1KE0 IILRDDAAMRAHAAALGVQD-YLLFAEMLMQRPV-RLGQLWGSHLLSREEAAYMVDMARE
.: : .. .. ::. : : ::: :: : ... .. .. : . . : .
CCDS45 LIWTDMKRVKEYSQRLGAGDLYPLFACMLTARSWDSVNRGISQAPVTATEDLEIRNNAAN
290 300 310 320 330 340
470 480 490 500 510
pF1KE0 RFEAVMAVLRELPRPMLLVLRNINTVRAINVALG--APVDRYFLMAKRAVRGWSRLAGAT
. . .: ..:: :::.:.. . .:.:..::: : .. .. :.. .: : :
CCDS45 YLPQISHLLNHVPRQMLLILKTNDLLRGIEAALGTRASASSFLNMSRCCIR-----ALAE
350 360 370 380 390
520 530 540 550 560 570
pF1KE0 YRGVYGTSLLRHAKV-------VWEMLKFEVALRLETLAM--RLTALLARALVHLSLVPP
.. :..:.... .:.. :. ::.. : . :. ::.
CCDS45 HKKKNTCSFFRRTQISFSEAFNLWQINLHELILRVKGLKLADRVLALICWLFPAPL
400 410 420 430 440 450
580
pF1KE0 AEELYQYLET
>>CCDS1557.1 COQ8A gene_id:56997|Hs108|chr1 (647 aa)
initn: 279 init1: 188 opt: 304 Z-score: 380.2 bits: 80.4 E(32554): 7.4e-15
Smith-Waterman score: 304; 22.8% identity (56.6% similar) in 417 aa overlap (71-476:201-603)
50 60 70 80 90 100
pF1KE0 SSPTPLWRKVLSTAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLD
:::.. . .. :: :: ..:
CCDS15 GGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFG-----GLAVGLG
180 190 200 210 220
110 120 130 140 150
pF1KE0 YWWCTNVVLRGVEENSP-GYLEVMSAC---HQRAADALVAGAISNGGLYVKLGQGLC-SF
. ..:. .... ..: : :... . :. .: . : .:::: : .
CCDS15 FGALAEVAKKSLRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQD
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE0 NHLLPPEYTRTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVH
. .. :. .. .. ... : .... . . .:. .. .. :. .:.::::..:::
CCDS15 DAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVH
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE0 RAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQD-LKGTLAQ
:... : ::.:.:: . . ...:...: .: . . : : : : : :. ::
CCDS15 LARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSN-MLPEGLFPEHLIDVLRRELAL
350 360 370 380 390 400
280 290 300 310 320 330
pF1KE0 ELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGL
: :.. :. :.. : :. ::.. . : .:::... .: ....:.. :: .
CCDS15 ECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGL-SQEI
410 420 430 440 450 460
340 350 360 370 380 390
pF1KE0 AVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDR
..: ... ...: :...::. .: . :. . ...::: : . ...
CCDS15 R-NEICYNILVLCLRELFEFHFMQTDPNWSNFFY--DPQ-QHKVALLDFGATREYDRSFT
470 480 490 500 510
400 410 420 430 440 450
pF1KE0 AALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQLW--GSHLLSREEA
:. :: :: ..::.. . .: :. ... ..: . : . : :
CCDS15 DLYIQIIRAAADRDRETVRAKSIEM---KFLTGYEVKVMEDAHLDAILILGEAFASDEPF
520 530 540 550 560 570
460 470 480 490 500
pF1KE0 AYMVDMARERFEAVMAVL---RELPRPMLLVLRNINTVRAINVALGAPVDRYFLMAKRAV
. .. . :... .. :. : .: :
CCDS15 DFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEA
580 590 600 610 620 630
>>CCDS12562.1 COQ8B gene_id:79934|Hs108|chr19 (544 aa)
initn: 246 init1: 218 opt: 277 Z-score: 347.1 bits: 74.1 E(32554): 5.2e-13
Smith-Waterman score: 277; 26.2% identity (56.7% similar) in 321 aa overlap (71-384:79-388)
50 60 70 80 90 100
pF1KE0 SSPTPLWRKVLSTAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLD
.::.. .. .. :: .: ::: ...
CCDS12 GPGRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFG-GLAVGLGLGVL
50 60 70 80 90 100
110 120 130 140 150
pF1KE0 YWWCTNVVLRGVEENSPGY-LEVMSACHQRAADALVAGAISNGGLYVKLGQGLC-SFNHL
. . : .. : :. . :. .: . : .:.:: : . : .
CCDS12 AEMAKKSMPGGRLQSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSF
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE0 LPPEYTRTLRVLEDRA--LKRG--FQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQV
. :. . .. ... : . : .. ..: . .:.:: : . :.::::..::
CCDS12 ISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASL----EEVPFAAASIGQV
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE0 HRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQ
:.. :.::: ::::.:: . . ...:...: .:.. .. .. :: :. ::
CCDS12 HQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAW
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 ELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGL
: :.. :. :. . ::. :. :: : . . ::: .. .: ... ... :: :
CCDS12 ECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGL-SQDL
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE0 AVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELV-LLDHGLYQFLEEKD
..: .:. ...: :...::. .: : :.... : ::: :
CCDS12 R-NQICFQLLTLCLRELFEFRFMQTDPNWANFLY----DASSHQVTLLDFGASREFGTEF
350 360 370 380 390
400 410 420 430 440 450
pF1KE0 RAALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAA
CCDS12 TDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDF
400 410 420 430 440 450
>>CCDS46081.1 COQ8B gene_id:79934|Hs108|chr19 (503 aa)
initn: 270 init1: 218 opt: 263 Z-score: 329.9 bits: 70.8 E(32554): 4.7e-12
Smith-Waterman score: 271; 28.5% identity (58.4% similar) in 274 aa overlap (128-384:81-347)
100 110 120 130 140 150
pF1KE0 SLDYWWCTNVVLRGVEENSPGYLEVMSACHQRAADALVAGAISN-GGLYVKLGQGLCSF-
.: . : . ..: ::: : :: :. .
CCDS46 GRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEM
60 70 80 90 100 110
160 170 180 190 200
pF1KE0 -NHLLPPEYTRTLRVLEDRALKRGFQEVDEL--FLEDFQALPHELFQEF--DYQ------
.. .: .. . . :.. :..: . :. .: : . : .:. :.:
CCDS46 AKKSMPGGRLQSDNSFISPQLQHIFERVRQSADFMPRWQML-RVLEEELGRDWQAKVASL
120 130 140 150 160
210 220 230 240 250 260
pF1KE0 ---PIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGF
:.::::..:::.. :.::: ::::.:: . . ...:...: .:.. .. ..
CCDS46 EEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFA
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE0 SWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGC
:: :. :: : :.. :. :. . ::. :. :: : . . ::: .. .:
CCDS46 EQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGV
230 240 250 260 270 280
330 340 350 360 370 380
pF1KE0 KVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELV-L
... ... :: : ..: .:. ...: :...::. .: : :.... : :
CCDS46 PLDQCQGL-SQDLR-NQICFQLLTLCLRELFEFRFMQTDPNWANFLY----DASSHQVTL
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE0 LDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQ
:: :
CCDS46 LDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMI
350 360 370 380 390 400
580 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:47:01 2016 done: Sat Nov 5 04:47:01 2016
Total Scan time: 3.430 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]