Result of FASTA (omim) for
pFN21AB6343
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6343, 264 aa
1>>>pF1KB6343 264 - 264 aa - 264 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2972+/-0.000339; mu= 3.3792+/- 0.021
mean_var=181.8356+/-36.582, 0's: 0 Z-trim(121.5): 5 B-trim: 410 in 1/59
Lambda= 0.095112
statistics sampled from 38314 (38319) to 38314 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.449), width: 16
Scan time: 7.860
The best scores are: opt bits E(85289)
NP_057683 (OMIM: 605602,613838) myozenin-2 [Homo s ( 264) 1789 256.7 3.1e-68
XP_006714297 (OMIM: 605602,613838) PREDICTED: myoz ( 195) 1276 186.3 3.7e-47
NP_067068 (OMIM: 605603) myozenin-1 [Homo sapiens] ( 299) 305 53.2 6.7e-07
NP_001116325 (OMIM: 610735) myozenin-3 [Homo sapie ( 251) 265 47.6 2.6e-05
NP_588612 (OMIM: 610735) myozenin-3 [Homo sapiens] ( 251) 265 47.6 2.6e-05
>>NP_057683 (OMIM: 605602,613838) myozenin-2 [Homo sapie (264 aa)
initn: 1789 init1: 1789 opt: 1789 Z-score: 1346.1 bits: 256.7 E(85289): 3.1e-68
Smith-Waterman score: 1789; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264)
10 20 30 40 50 60
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 DNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 DYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWI
190 200 210 220 230 240
250 260
pF1KB6 SENIPIVITTEPTDDTTVPESEDL
::::::::::::::::::::::::
NP_057 SENIPIVITTEPTDDTTVPESEDL
250 260
>>XP_006714297 (OMIM: 605602,613838) PREDICTED: myozenin (195 aa)
initn: 1276 init1: 1276 opt: 1276 Z-score: 967.5 bits: 186.3 E(85289): 3.7e-47
Smith-Waterman score: 1276; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187)
10 20 30 40 50 60
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 DNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 DYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWI
:::::::
XP_006 DYRSFNRGSRLHWRK
190
>>NP_067068 (OMIM: 605603) myozenin-1 [Homo sapiens] (299 aa)
initn: 524 init1: 271 opt: 305 Z-score: 244.8 bits: 53.2 E(85289): 6.7e-07
Smith-Waterman score: 470; 35.2% identity (58.2% similar) in 287 aa overlap (9-257:11-296)
10 20 30 40 50
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLF
:.::.. . :.. .:..::::.:.:::.:::::: :.:::...:
NP_067 MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMF
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 KMRQRRSDKYTFENF-QYQSRAQINH------SIAMQNGKV-DG-----SNLEGGSQQAP
:.:: : .:. .:: . : ....: ... : : . .: :: .:::: .
NP_067 KLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGG
70 80 90 100 110 120
110 120 130 140
pF1KB6 LTPPNT--PDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTA-------------------V
. : . . . : : .:: . :: :
NP_067 SGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITV
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 PKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASRMVKF
: : ::::.:.. ::. : :. .::::: :.::::.: :.::.::::. . :
NP_067 FKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTF
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB6 KVPDFELL-LLTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTE---PTDDTTVPE
..: :.: ::..: .. . . ::.: :::::: :.: . :. ... : : :
NP_067 QMPKFDLGPLLSEP-LVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL
250 260 270 280 290
pF1KB6 SEDL
>>NP_001116325 (OMIM: 610735) myozenin-3 [Homo sapiens] (251 aa)
initn: 449 init1: 184 opt: 265 Z-score: 216.3 bits: 47.6 E(85289): 2.6e-05
Smith-Waterman score: 436; 34.1% identity (58.3% similar) in 264 aa overlap (9-245:4-246)
10 20 30 40 50 60
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
:..: . : : .. . : .:::::.:.:.:.:.:::: .:::. ::.
NP_001 MIPKEQKGPVMAAMGDLT-EPVPTLDLGKKLSVPQDLMMEELSLRNNRGSLLFQK
10 20 30 40 50
70 80 90 100
pF1KB6 RQRRSDKYTFENFQYQSRAQINHS-------------IAMQNGKVDGSNLEGGSQQAPLT
:::: .:.::: . ..::.. : .: :: .: : .. . : .
NP_001 RQRRVQKFTFE-LAASQRAMLAGSARRKVTGTAESGTVANANGP-EGPNYRSELHIFPAS
60 70 80 90 100 110
110 120 130 140 150
pF1KB6 PPNT---PDPRSP--------PNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAI
: . :. : :.:. .::::. ::: .:::::: ::. : :. ::.. .
NP_001 PGASLGGPEGAHPAAAPAGCVPSPSALAPGYAEPLKGVPPEKFNHTAISKGYRCPWQEFV
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 SNDPELLEALYPKLFKPEGKAELP---DYRSFNRVATPFGGFEKASRMVKFKVPDFELLL
: . .. .:... : :::.::.. .:::: .. : : ..
NP_001 SY----------RDYQSDGRSHTPSPNDYRNFNKTPVPFGGPLVGG---TFPRPGTPFI-
180 190 200 210
220 230 240 250 260
pF1KB6 LTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL
:. .: .. : : ::::. .::. .:.:
NP_001 ---PEPLSGLELLRLRPSFNRVAQGWV-RNLPESEEL
220 230 240 250
>>NP_588612 (OMIM: 610735) myozenin-3 [Homo sapiens] (251 aa)
initn: 449 init1: 184 opt: 265 Z-score: 216.3 bits: 47.6 E(85289): 2.6e-05
Smith-Waterman score: 436; 34.1% identity (58.3% similar) in 264 aa overlap (9-245:4-246)
10 20 30 40 50 60
pF1KB6 MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKM
:..: . : : .. . : .:::::.:.:.:.:.:::: .:::. ::.
NP_588 MIPKEQKGPVMAAMGDLT-EPVPTLDLGKKLSVPQDLMMEELSLRNNRGSLLFQK
10 20 30 40 50
70 80 90 100
pF1KB6 RQRRSDKYTFENFQYQSRAQINHS-------------IAMQNGKVDGSNLEGGSQQAPLT
:::: .:.::: . ..::.. : .: :: .: : .. . : .
NP_588 RQRRVQKFTFE-LAASQRAMLAGSARRKVTGTAESGTVANANGP-EGPNYRSELHIFPAS
60 70 80 90 100 110
110 120 130 140 150
pF1KB6 PPNT---PDPRSP--------PNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAI
: . :. : :.:. .::::. ::: .:::::: ::. : :. ::.. .
NP_588 PGASLGGPEGAHPAAAPAGCVPSPSALAPGYAEPLKGVPPEKFNHTAISKGYRCPWQEFV
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 SNDPELLEALYPKLFKPEGKAELP---DYRSFNRVATPFGGFEKASRMVKFKVPDFELLL
: . .. .:... : :::.::.. .:::: .. : : ..
NP_588 SY----------RDYQSDGRSHTPSPNDYRNFNKTPVPFGGPLVGG---TFPRPGTPFI-
180 190 200 210
220 230 240 250 260
pF1KB6 LTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL
:. .: .. : : ::::. .::. .:.:
NP_588 ---PEPLSGLELLRLRPSFNRVAQGWV-RNLPESEEL
220 230 240 250
264 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:00:31 2016 done: Sat Nov 5 04:00:32 2016
Total Scan time: 7.860 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]