Result of FASTA (ccds) for
pFN21AE0654
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0654, 386 aa
1>>>pF1KE0654 386 - 386 aa - 386 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3105+/-0.00112; mu= 13.1476+/- 0.067
mean_var=151.0317+/-31.836, 0's: 0 Z-trim(108.1): 174 B-trim: 471 in 1/51
Lambda= 0.104361
statistics sampled from 9796 (10010) to 9796 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.307), width: 16
Scan time: 1.810
The best scores are: opt bits E(32554)
CCDS1901.1 TIA1 gene_id:7072|Hs108|chr2 ( 386) 2691 417.2 1.2e-116
CCDS1900.1 TIA1 gene_id:7072|Hs108|chr2 ( 375) 2010 314.7 8.7e-86
CCDS31295.1 TIAL1 gene_id:7073|Hs108|chr10 ( 392) 1697 267.6 1.4e-71
CCDS7613.1 TIAL1 gene_id:7073|Hs108|chr10 ( 375) 1516 240.3 2.1e-63
CCDS9311.1 PABPC3 gene_id:5042|Hs108|chr13 ( 631) 413 74.5 3e-13
>>CCDS1901.1 TIA1 gene_id:7072|Hs108|chr2 (386 aa)
initn: 2691 init1: 2691 opt: 2691 Z-score: 2207.6 bits: 417.2 E(32554): 1.2e-116
Smith-Waterman score: 2691; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KE0 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV
310 320 330 340 350 360
370 380
pF1KE0 QPPQGQNGSMLPNQPSGYRVAGYETQ
::::::::::::::::::::::::::
CCDS19 QPPQGQNGSMLPNQPSGYRVAGYETQ
370 380
>>CCDS1900.1 TIA1 gene_id:7072|Hs108|chr2 (375 aa)
initn: 2004 init1: 2004 opt: 2010 Z-score: 1653.6 bits: 314.7 E(32554): 8.7e-86
Smith-Waterman score: 2592; 96.9% identity (97.2% similar) in 386 aa overlap (1-386:1-375)
10 20 30 40 50 60
pF1KE0 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE
:::::::::::::::::::::::::::::::: .::::::::::::::::
CCDS19 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTS-----------NHFHVFVGDLSPEITTE
70 80 90 100
130 140 150 160 170 180
pF1KE0 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 WATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 GYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGV
290 300 310 320 330 340
370 380
pF1KE0 QPPQGQNGSMLPNQPSGYRVAGYETQ
::::::::::::::::::::::::::
CCDS19 QPPQGQNGSMLPNQPSGYRVAGYETQ
350 360 370
>>CCDS31295.1 TIAL1 gene_id:7073|Hs108|chr10 (392 aa)
initn: 1637 init1: 1163 opt: 1697 Z-score: 1398.7 bits: 267.6 E(32554): 1.4e-71
Smith-Waterman score: 1962; 74.0% identity (84.1% similar) in 408 aa overlap (1-386:2-392)
10 20 30 40
pF1KE0 MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD---------TAG-----
:::. .:.:::::::::::::.:::::::::::::.:::: . ..:
CCDS31 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 ---NDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQR
:::::::::.::: :::::::::::::.::::::::::::::::::::
CCDS31 HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTS---------
70 80 90 100 110
110 120 130 140 150 160
pF1KE0 SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE
.:::::::::::::::::::.::::::.:::::::::::::::::::::::.:: :::
CCDS31 --NHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE
120 130 140 150 160
170 180 190 200 210 220
pF1KE0 NAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGV
::: .:::::::::::::::::::::::::: :.::::: ...:::::::.::::::::.
CCDS31 NAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGI
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE0 TSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC
.::::.::::::::::::::::::::.::::::::..:::::::::::::::::::::::
CCDS31 ASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKC
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE0 YWGKETLDMINPVQQQNQIGYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQ
:::::. :: . : :. : : .:::.: ::: :: :::: :::::: ::.::: :::
CCDS31 YWGKESPDMTKNFQ---QVDYSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQ
290 300 310 320 330 340
350 360 370 380
pF1KE0 QGFNQTQS-SAPWMGPNYGVQPPQGQNGSML---PNQPSGYRVAGYETQ
:::. :: :: ::: ..:.:::::: . ::: .:: .:.:.::
CCDS31 QGFGVDQSPSAAWMG-GFGAQPPQGQAPPPVIPPPNQ-AGYGMASYQTQ
350 360 370 380 390
>>CCDS7613.1 TIAL1 gene_id:7073|Hs108|chr10 (375 aa)
initn: 1450 init1: 1163 opt: 1516 Z-score: 1251.6 bits: 240.3 E(32554): 2.1e-63
Smith-Waterman score: 2004; 77.0% identity (87.5% similar) in 391 aa overlap (1-386:2-375)
10 20 30 40 50
pF1KE0 MEDE-MPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRH
:::. .:.:::::::::::::.:::::::::::::.:::: . ..:::::::::.:::
CCDS76 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 AAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEIT
:::::::::::::.:::::::::::::::::::: .::::::::::::::
CCDS76 AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTS-----------NHFHVFVGDLSPEIT
70 80 90 100
120 130 140 150 160 170
pF1KE0 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR
:::::.::::::.:::::::::::::::::::::::.:: :::::: .::::::::::::
CCDS76 TEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 TNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFG
:::::::::::::: :.::::: ...:::::::.::::::::..::::.:::::::::::
CCDS76 TNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 QIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQN
:::::::::.::::::::..::::::::::::::::::::::::::::. :: . :
CCDS76 QIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQ---
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 QIGYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWMGPN
:. : : .:::.: ::: :: :::: :::::: ::.::: ::::::. :: :: ::: .
CCDS76 QVDYSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG-G
290 300 310 320 330 340
360 370 380
pF1KE0 YGVQPPQGQNGSML---PNQPSGYRVAGYETQ
.:.:::::: . ::: .:: .:.:.::
CCDS76 FGAQPPQGQAPPPVIPPPNQ-AGYGMASYQTQ
350 360 370
>>CCDS9311.1 PABPC3 gene_id:5042|Hs108|chr13 (631 aa)
initn: 264 init1: 152 opt: 413 Z-score: 351.5 bits: 74.5 E(32554): 3e-13
Smith-Waterman score: 419; 25.9% identity (55.9% similar) in 401 aa overlap (9-386:101-482)
10 20 30
pF1KE0 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKM
..: ::...... . . : .: .:..
CCDS93 TMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNV
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE0 IMDTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVS
. : :. : ::.:. :. : :. ::: . :..: :. : :. . .
CCDS93 VCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVG-------QFKSRKEREAEL
140 150 160 170 180
100 110 120 130 140 150
pF1KE0 TQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKW
:... .:.. ... .. : .: :. :: ...:. : .:::::.::::: .
CCDS93 GARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHE
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE0 DAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC
::..:...:.:. :.:.:: .. : .: .. . . .:.. :... . ..:
CCDS93 DAQKAVDEMNGKELNGKQIYVGRAQKKVER-QTELKRTFEQMKQDRITRYQV---VNLYV
250 260 270 280 290
220 230 240 250 260 270
pF1KE0 GGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNGTTI
.. .:. .. .:..::::: : .:. . ::..:: :.: : :..:.. .:: .
CCDS93 KNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIV
300 310 320 330 340 350
280 290 300 310 320
pF1KE0 EGHVV-----------KCYWGKETLDMINPVQQQNQIGYPQPYGQWGQWYGNAQQIGQYM
. . . : .: .. . :. . : : : . ..:. . :.
CCDS93 ATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPNQRAP-PSGYFMTAVPQTQNHAAYY
360 370 380 390 400 410
330 340 350 360 370
pF1KE0 PNGWQVPAYGMYGQAWNQQGFN----QTQSSAPWMG----PNYGVQPPQGQNGSMLPNQP
: . :. : . :. :: :.. :: : : ..: ..: .:
CCDS93 PPS-QI-ARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQ----VPRVM
420 430 440 450 460 470
380
pF1KE0 SGYRVAGYETQ
: :::. ::
CCDS93 STQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLA
480 490 500 510 520 530
386 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:46:17 2016 done: Wed Nov 2 18:46:17 2016
Total Scan time: 1.810 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]