Result of FASTA (omim) for
pFN21AE0569
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0569, 194 aa
1>>>pF1KE0569 194 - 194 aa - 194 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2606+/-0.000365; mu= 13.5380+/- 0.023
mean_var=63.7721+/-13.004, 0's: 0 Z-trim(113.1): 11 B-trim: 0 in 0/52
Lambda= 0.160605
statistics sampled from 22222 (22232) to 22222 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.261), width: 16
Scan time: 5.830
The best scores are: opt bits E(85289)
NP_072098 (OMIM: 171490) phosducin isoform b [Homo ( 194) 1271 302.9 2.1e-82
NP_002588 (OMIM: 171490) phosducin isoform a [Homo ( 246) 1271 303.0 2.6e-82
XP_011507905 (OMIM: 171490) PREDICTED: phosducin i ( 246) 1271 303.0 2.6e-82
NP_005379 (OMIM: 604421) phosducin-like protein [H ( 301) 646 158.2 1.2e-38
XP_016870274 (OMIM: 604421) PREDICTED: phosducin-l ( 236) 613 150.5 1.9e-36
NP_076970 (OMIM: 611678) phosducin-like protein 3 ( 239) 206 56.2 4.8e-08
XP_016860379 (OMIM: 611678) PREDICTED: phosducin-l ( 189) 203 55.4 6.4e-08
XP_011532676 (OMIM: 611676) PREDICTED: phosducin-l ( 209) 202 55.2 8.2e-08
NP_689614 (OMIM: 611676) phosducin-like protein 2 ( 241) 202 55.3 9.2e-08
>>NP_072098 (OMIM: 171490) phosducin isoform b [Homo sap (194 aa)
initn: 1271 init1: 1271 opt: 1271 Z-score: 1600.4 bits: 302.9 E(85289): 2.1e-82
Smith-Waterman score: 1271; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:1-194)
10 20 30 40 50 60
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 FVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 SNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 SNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREV
130 140 150 160 170 180
190
pF1KE0 HVLEHTKIEEEDVE
::::::::::::::
NP_072 HVLEHTKIEEEDVE
190
>>NP_002588 (OMIM: 171490) phosducin isoform a [Homo sap (246 aa)
initn: 1271 init1: 1271 opt: 1271 Z-score: 1598.9 bits: 303.0 E(85289): 2.6e-82
Smith-Waterman score: 1271; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:53-246)
10 20 30
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHK
::::::::::::::::::::::::::::::
NP_002 KGVINDWRKFKLESQDSDSIPPSKKEILRQMSSPQSRNGKDSKERVSRKMSIQEYELIHK
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 EKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYE
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE0 DGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFI
150 160 170 180 190 200
160 170 180 190
pF1KE0 SVAEQFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
::::::::::::::::::::::::::::::::::::::::::::
NP_002 SVAEQFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
210 220 230 240
>>XP_011507905 (OMIM: 171490) PREDICTED: phosducin isofo (246 aa)
initn: 1271 init1: 1271 opt: 1271 Z-score: 1598.9 bits: 303.0 E(85289): 2.6e-82
Smith-Waterman score: 1271; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:53-246)
10 20 30
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHK
::::::::::::::::::::::::::::::
XP_011 KGVINDWRKFKLESQDSDSIPPSKKEILRQMSSPQSRNGKDSKERVSRKMSIQEYELIHK
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE0 EKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYE
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE0 DGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFI
150 160 170 180 190 200
160 170 180 190
pF1KE0 SVAEQFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVAEQFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
210 220 230 240
>>NP_005379 (OMIM: 604421) phosducin-like protein [Homo (301 aa)
initn: 683 init1: 645 opt: 646 Z-score: 814.9 bits: 158.2 E(85289): 1.2e-38
Smith-Waterman score: 646; 49.2% identity (84.2% similar) in 183 aa overlap (5-187:104-286)
10 20 30
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKED
.... :: .:..: ::...:. .......:
NP_005 TEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDD
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE0 ENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIK
:. :..::.: :..:.:.: ::.. :.:. .:. ::. :.:: : .:.::::::::
NP_005 EEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIP
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE0 GCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAE
: .:.:. . ::::::: :::::.:.: ::...:. ..::.::::::::::.::. :..
NP_005 GTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTRNALPALLIYKGGELIGNFVRVTD
200 210 220 230 240 250
160 170 180 190
pF1KE0 QFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
:....::: :.:.::.:.:::::.:: :: ..
NP_005 QLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID
260 270 280 290 300
>>XP_016870274 (OMIM: 604421) PREDICTED: phosducin-like (236 aa)
initn: 615 init1: 577 opt: 613 Z-score: 775.2 bits: 150.5 E(85289): 1.9e-36
Smith-Waterman score: 613; 50.3% identity (84.6% similar) in 169 aa overlap (19-187:53-221)
10 20 30 40
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQD
.:...:. .......::. :..::.: :..
XP_016 TRTRTEADVPQPAVLCLQRLSWQAKASQLTQMTLKEFAIMNEDQDDEEFLQQYRKQRMEE
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE0 MHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAA
:.:.: ::.. :.:. .:. ::. :.:: : .:.:::::::: : .:.:. . ::::
XP_016 MRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAA
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE0 EYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESF
::: :::::.:.: ::...:. ..::.::::::::::.::. :..:....::: :.:.:
XP_016 EYPAVKFCKVKSSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAF
150 160 170 180 190 200
170 180 190
pF1KE0 LNEYGLLPEREVHVLEHTKIEEEDVE
:.:.:::::.:: :: ..
XP_016 LQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID
210 220 230
>>NP_076970 (OMIM: 611678) phosducin-like protein 3 [Hom (239 aa)
initn: 145 init1: 118 opt: 206 Z-score: 265.4 bits: 56.2 E(85289): 4.8e-08
Smith-Waterman score: 206; 28.4% identity (62.2% similar) in 148 aa overlap (5-150:36-179)
10 20 30
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHKE--K
..: ..: .. . :...: : . : .
NP_076 ADTEWNDILRKKGILPPKESLKELEEEAEEEQRILQQSVVKTYEDMTLEELEDHEDEFNE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 EDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDG
::: .. :::. . . . .. ..: : :. .::.... . : . ...:.:..:
NP_076 EDERAIEMYRRRRLAEW-KATKLKNKFGEVLEI-SGKDYVQEVTKAGEGLWVILHLYKQG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 IKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISV
: : .:. :. :: ..: ::: ::: .: . :::...: :.. ..::
NP_076 IPLCALINQHLSGLARKFPDVKF--IKAISTTCIPNYPDRNLPTIFVYLEGDIKAQFIGP
130 140 150 160 170 180
160 170 180 190
pF1KE0 AEQFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
NP_076 LVFGGMNLTRDELEWKLSESGAIMTDLEENPKKPIEDVLLSSVRRSVLMKRDSDSEGD
190 200 210 220 230
>>XP_016860379 (OMIM: 611678) PREDICTED: phosducin-like (189 aa)
initn: 145 init1: 118 opt: 203 Z-score: 263.2 bits: 55.4 E(85289): 6.4e-08
Smith-Waterman score: 203; 30.1% identity (62.4% similar) in 133 aa overlap (20-150:1-129)
10 20 30 40 50
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHKE--KEDENCLRKYRRQCMQDMHQKLSFGPR
:...: : . : .::: .. :::. . . . .. .
XP_016 MTLEELEDHEDEFNEEDERAIEMYRRRRLAEW-KATKLKNK
10 20 30 40
60 70 80 90 100 110
pF1KE0 YGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKI
.: : :. .::.... . : . ...:.:..:: : .:. :. :: ..: ::: :
XP_016 FGEVLEI-SGKDYVQEVTKAGEGLWVILHLYKQGIPLCALINQHLSGLARKFPDVKF--I
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 KASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPER
:: .: . :::...: :.. ..::
XP_016 KAISTTCIPNYPDRNLPTIFVYLEGDIKAQFIGPLVFGGMNLTRDELEWKLSESGAIMTD
100 110 120 130 140 150
180 190
pF1KE0 EVHVLEHTKIEEEDVE
XP_016 LEENPKKPIEDVLLSSVRRSVLMKRDSDSEGD
160 170 180
>>XP_011532676 (OMIM: 611676) PREDICTED: phosducin-like (209 aa)
initn: 143 init1: 73 opt: 202 Z-score: 261.3 bits: 55.2 E(85289): 8.2e-08
Smith-Waterman score: 202; 24.7% identity (66.0% similar) in 150 aa overlap (7-154:4-149)
10 20 30 40 50
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHKE--KEDENCLRKYRRQCMQDMHQKLSFGPR
: :.. . .::.. . . . : .:: . .. ::.. .:. . :. .
XP_011 MVLRLQKEAMVKPFEKMTLAQLKEAEDEFDEEDMQAVETYRKKRLQEW-KALKKKQK
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 YGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKI
.: . :. .:.:... . . . . ...:.:...: : .:. :. :: ..: .:: .
XP_011 FGELREI-SGNQYVNEVTNAEEDVWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKF--V
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 KASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPER
:: .. ... . :::...::.:.. ..::.. :
XP_011 KAIVNSCIQHYHDNCLPTIFVYKNGQIEAKFIGIIECGGINLKLEELEWKLAEVGAIQTD
120 130 140 150 160 170
180 190
pF1KE0 EVHVLEHTKIEEEDVE
XP_011 LEENPRKDMVDMMVSSIRNTSIHDDSDSSNSDNDTK
180 190 200
>>NP_689614 (OMIM: 611676) phosducin-like protein 2 [Hom (241 aa)
initn: 143 init1: 73 opt: 202 Z-score: 260.3 bits: 55.3 E(85289): 9.2e-08
Smith-Waterman score: 202; 24.7% identity (66.0% similar) in 150 aa overlap (7-154:36-181)
10 20 30
pF1KE0 MSSPQSRNGKDSKERVSRKMSIQEYELIHKE--KED
: :.. . .::.. . . . : .::
NP_689 EDTEWNDILRDFGILPPKEESKDEIEEMVLRLQKEAMVKPFEKMTLAQLKEAEDEFDEED
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 ENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIK
. .. ::.. .:. . :. ..: . :. .:.:... . . . . ...:.:...:
NP_689 MQAVETYRKKRLQEW-KALKKKQKFGELREI-SGNQYVNEVTNAEEDVWVIIHLYRSSIP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 GCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAE
: .:. :. :: ..: .:: .:: .. ... . :::...::.:.. ..::.. :
NP_689 MCLLVNQHLSLLARKFPETKF--VKAIVNSCIQHYHDNCLPTIFVYKNGQIEAKFIGIIE
130 140 150 160 170 180
160 170 180 190
pF1KE0 QFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
NP_689 CGGINLKLEELEWKLAEVGAIQTDLEENPRKDMVDMMVSSIRNTSIHDDSDSSNSDNDTK
190 200 210 220 230 240
194 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:52:11 2016 done: Wed Nov 2 22:52:12 2016
Total Scan time: 5.830 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]