Result of FASTA (omim) for
pFN21AE0238
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0238, 162 aa
1>>>pF1KE0238 162 - 162 aa - 162 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0018+/-0.000359; mu= 13.1086+/- 0.022
mean_var=57.4511+/-12.064, 0's: 0 Z-trim(113.1): 32 B-trim: 1242 in 1/49
Lambda= 0.169210
statistics sampled from 22279 (22311) to 22279 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.262), width: 16
Scan time: 5.440
The best scores are: opt bits E(85289)
NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [H ( 162) 1034 260.5 8.8e-70
XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like s ( 195) 1017 256.3 1.8e-68
XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like s ( 162) 728 185.8 2.7e-47
NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 ( 162) 728 185.8 2.7e-47
NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [H ( 162) 728 185.8 2.7e-47
XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like s ( 177) 728 185.8 2.9e-47
NP_004576 (OMIM: 605092) retinoic acid receptor re ( 164) 527 136.7 1.6e-32
XP_016862412 (OMIM: 606487) PREDICTED: phospholipi ( 168) 467 122.0 4.2e-28
NP_065119 (OMIM: 606487) phospholipid-metabolizing ( 273) 467 122.2 6.4e-28
XP_016872661 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159) 457 119.6 2.2e-27
XP_011543055 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 159) 457 119.6 2.2e-27
XP_011543053 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 268) 457 119.7 3.4e-27
NP_001140201 (OMIM: 611474) Ca(2+)-independent N-a ( 269) 457 119.7 3.4e-27
NP_473449 (OMIM: 611474) Ca(2+)-independent N-acyl ( 279) 457 119.7 3.5e-27
XP_011511337 (OMIM: 606487) PREDICTED: phospholipi ( 339) 439 115.4 8.7e-26
XP_011511336 (OMIM: 606487) PREDICTED: phospholipi ( 342) 439 115.4 8.8e-26
NP_001140200 (OMIM: 611474) Ca(2+)-independent N-a ( 253) 351 93.8 2e-19
XP_011543054 (OMIM: 611474) PREDICTED: Ca(2+)-inde ( 167) 283 77.1 1.4e-14
NP_001288574 (OMIM: 268000,604863,613341) lecithin ( 230) 149 44.5 0.00013
NP_004735 (OMIM: 268000,604863,613341) lecithin re ( 230) 149 44.5 0.00013
>>NP_060348 (OMIM: 613866) HRAS-like suppressor 2 [Homo (162 aa)
initn: 1034 init1: 1034 opt: 1034 Z-score: 1373.8 bits: 260.5 E(85289): 8.8e-70
Smith-Waterman score: 1034; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)
10 20 30 40 50 60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
70 80 90 100 110 120
130 140 150 160
pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
::::::::::::::::::::::::::::::::::::::::::
NP_060 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
130 140 150 160
>>XP_011543422 (OMIM: 613866) PREDICTED: HRAS-like suppr (195 aa)
initn: 1017 init1: 1017 opt: 1017 Z-score: 1350.1 bits: 256.3 E(85289): 1.8e-68
Smith-Waterman score: 1017; 100.0% identity (100.0% similar) in 159 aa overlap (4-162:37-195)
10 20 30
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYV
::::::::::::::::::::::::::::::
XP_011 SQRVFQFWLQSICIPTLKLFVCLFVYSLKRARPRPRLGDLIEISRFGYAHWAIYVGDGYV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 VHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 KRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGIL
130 140 150 160 170 180
160
pF1KE0 LARSKRERQ
:::::::::
XP_011 LARSKRERQ
190
>>XP_006718489 (OMIM: 613867) PREDICTED: HRAS-like suppr (162 aa)
initn: 729 init1: 709 opt: 728 Z-score: 970.1 bits: 185.8 E(85289): 2.7e-47
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162)
10 20 30 40 50 60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
:.:. :::::: : : :::::::::::::::: ::.::::::::.::::.::::
XP_006 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
::::: :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.:
XP_006 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
::::.::::: .. ...::. ::: ::.:....:.::..:
XP_006 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>NP_001121675 (OMIM: 613867) HRAS-like suppressor 3 [Ho (162 aa)
initn: 729 init1: 709 opt: 728 Z-score: 970.1 bits: 185.8 E(85289): 2.7e-47
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162)
10 20 30 40 50 60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
:.:. :::::: : : :::::::::::::::: ::.::::::::.::::.::::
NP_001 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
::::: :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.:
NP_001 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
::::.::::: .. ...::. ::: ::.:....:.::..:
NP_001 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>NP_009000 (OMIM: 613867) HRAS-like suppressor 3 [Homo (162 aa)
initn: 729 init1: 709 opt: 728 Z-score: 970.1 bits: 185.8 E(85289): 2.7e-47
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:6-162)
10 20 30 40 50 60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
:.:. :::::: : : :::::::::::::::: ::.::::::::.::::.::::
NP_009 MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
::::: :::.:.:.:::::::.:.::: .::..:::::::::. :.:::.:::::::.:
NP_009 KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
70 80 90 100 110 120
130 140 150 160
pF1KE0 RYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
::::.::::: .. ...::. ::: ::.:....:.::..:
NP_009 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160
>>XP_011543043 (OMIM: 613867) PREDICTED: HRAS-like suppr (177 aa)
initn: 729 init1: 709 opt: 728 Z-score: 969.5 bits: 185.8 E(85289): 2.9e-47
Smith-Waterman score: 728; 69.4% identity (89.8% similar) in 157 aa overlap (6-162:21-177)
10 20 30 40
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGA
:.:. :::::: : : :::::::::::::::: ::.:::
XP_011 MKTQRSSWCQLLLHRIGQRIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 GAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELP
:::::.::::.::::::::: :::.:.:.:::::::.:.::: .::..:::::::::.
XP_011 GAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 YSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
:.:::.:::::::.:::::.::::: .. ...::. ::: ::.:....:.::..:
XP_011 YKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
130 140 150 160 170
>>NP_004576 (OMIM: 605092) retinoic acid receptor respon (164 aa)
initn: 526 init1: 526 opt: 527 Z-score: 704.8 bits: 136.7 E(85289): 1.6e-32
Smith-Waterman score: 527; 55.7% identity (77.9% similar) in 149 aa overlap (1-147:1-149)
10 20 30 40 50 60
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIV
:: . .:. :::::: :.:: :::.:.:::::.:::: :: :::..::.:.:.:.: :
NP_004 MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHL
:.: : :.:: :::::. : .: : : . :.. :.:.:::.. ::..: ::::::..:
NP_004 KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL
70 80 90 100 110 120
130 140 150 160
pF1KE0 RYGVSRSDQVTGAVTTVGVAA--GLLAAASLVGILLARSKRERQ
::: :: :: : . ::::. :.:..:
NP_004 RYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA
130 140 150 160
>>XP_016862412 (OMIM: 606487) PREDICTED: phospholipid-me (168 aa)
initn: 449 init1: 310 opt: 467 Z-score: 625.5 bits: 122.0 E(85289): 4.2e-28
Smith-Waterman score: 467; 45.3% identity (78.9% similar) in 161 aa overlap (2-161:8-166)
10 20 30 40 50
pF1KE0 MALARP-RPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSA
.: : : :::::. : :: :::.:.:::::...::.. : :. .:. :.
XP_016 MAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNC
...::.:: .::. :.:.:.::.:::.:. : ::: ..:.::.: ..:::. :.: .::
XP_016 FSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNC
60 70 80 90 100 110
120 130 140 150 160
pF1KE0 EHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
::::. :::: . :.:.. :..:: ... ... :..: :. ...: .
XP_016 EHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLG-LFPKGQRAKYY
120 130 140 150 160
>>NP_065119 (OMIM: 606487) phospholipid-metabolizing enz (273 aa)
initn: 473 init1: 310 opt: 467 Z-score: 622.3 bits: 122.2 E(85289): 6.4e-28
Smith-Waterman score: 467; 45.3% identity (78.9% similar) in 161 aa overlap (2-161:113-271)
10 20 30
pF1KE0 MALARP-RPRLGDLIEISRFGYAHWAIYVGD
.: : : :::::. : :: :::.:.::
NP_065 PRETPGHTQLPPGARRRPRLESEMAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGD
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE0 GYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSN
:::...::.. : :. .:. :....::.:: .::. :.:.:.::.:::.:. : ::: .
NP_065 GYVINIAPVDGIP-ASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVE
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE0 KIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLV
.:.::.: ..:::. :.: .::::::. :::: . :.:.. :..:: ... ... :..
NP_065 EIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFL
210 220 230 240 250 260
160
pF1KE0 GILLARSKRERQ
: :. ...: .
NP_065 G-LFPKGQRAKYY
270
>>XP_016872661 (OMIM: 611474) PREDICTED: Ca(2+)-independ (159 aa)
initn: 425 init1: 249 opt: 457 Z-score: 612.6 bits: 119.6 E(85289): 2.2e-27
Smith-Waterman score: 457; 51.4% identity (71.2% similar) in 146 aa overlap (2-147:4-147)
10 20 30 40 50
pF1KE0 MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKA
....:::: :::::: :.:: :::::: : :::::: :: .: :. : ..:.:
XP_016 MSRSVGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 IVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVN
.:: : : : ...:::: : : ::: .::..:....:.. . ::: :::::::
XP_016 VVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVN
60 70 80 90 100 110
120 130 140 150 160
pF1KE0 HLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ
::::: ::.:: :. . ::: . .:
XP_016 GLRYGVPRSQQVEHALMEGAKAAGAVISAVVDSIKPKPITA
120 130 140 150
162 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:53:33 2016 done: Thu Nov 3 19:53:34 2016
Total Scan time: 5.440 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]