Result of FASTA (omim) for
pFN21AB6840
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6840, 191 aa
1>>>pF1KB6840 191 - 191 aa - 191 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8690+/-0.000366; mu= 15.1237+/- 0.022
mean_var=62.6865+/-13.057, 0's: 0 Z-trim(112.7): 23 B-trim: 911 in 1/52
Lambda= 0.161990
statistics sampled from 21736 (21754) to 21736 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.255), width: 16
Scan time: 5.340
The best scores are: opt bits E(85289)
NP_004128 (OMIM: 603951,608622) calcium-activated ( 191) 1272 305.7 2.9e-83
NP_005823 (OMIM: 605214) calcium-activated potassi ( 235) 534 133.3 2.8e-31
NP_852006 (OMIM: 605214) calcium-activated potassi ( 235) 534 133.3 2.8e-31
NP_001265840 (OMIM: 605214) calcium-activated pota ( 235) 534 133.3 2.8e-31
XP_011510627 (OMIM: 605214) PREDICTED: calcium-act ( 235) 534 133.3 2.8e-31
NP_741980 (OMIM: 605222) calcium-activated potassi ( 257) 235 63.5 3.3e-10
NP_741981 (OMIM: 605222) calcium-activated potassi ( 275) 235 63.5 3.5e-10
NP_741979 (OMIM: 605222) calcium-activated potassi ( 277) 235 63.5 3.5e-10
NP_055222 (OMIM: 605222) calcium-activated potassi ( 279) 235 63.5 3.5e-10
NP_055320 (OMIM: 605223) calcium-activated potassi ( 210) 167 47.5 1.7e-05
NP_001157149 (OMIM: 605222) calcium-activated pota ( 173) 127 38.1 0.0096
>>NP_004128 (OMIM: 603951,608622) calcium-activated pota (191 aa)
initn: 1272 init1: 1272 opt: 1272 Z-score: 1615.8 bits: 305.7 E(85289): 2.9e-83
Smith-Waterman score: 1272; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS
130 140 150 160 170 180
190
pF1KB6 NQYLSILAAQK
:::::::::::
NP_004 NQYLSILAAQK
190
>>NP_005823 (OMIM: 605214) calcium-activated potassium c (235 aa)
initn: 532 init1: 339 opt: 534 Z-score: 682.4 bits: 133.3 E(85289): 2.8e-31
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226)
10 20 30
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
.: : : : :: ::. ::..:.::... :.
NP_005 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
10 20 30 40 50 60
40 50 60 70 80
pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
.: :.: :..::::.::.: :....: . . . : :. ::::: .::....
NP_005 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
:. .:::::.: ::.::::: :.. . . :. : .:.. : : :.: :.::.
NP_005 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
130 140 150 160 170 180
150 160 170 180 190
pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
::.. .::. ..:. :::::: ...::. :.:::: .::::.:
NP_005 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
190 200 210 220 230
>>NP_852006 (OMIM: 605214) calcium-activated potassium c (235 aa)
initn: 532 init1: 339 opt: 534 Z-score: 682.4 bits: 133.3 E(85289): 2.8e-31
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226)
10 20 30
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
.: : : : :: ::. ::..:.::... :.
NP_852 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
10 20 30 40 50 60
40 50 60 70 80
pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
.: :.: :..::::.::.: :....: . . . : :. ::::: .::....
NP_852 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
:. .:::::.: ::.::::: :.. . . :. : .:.. : : :.: :.::.
NP_852 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
130 140 150 160 170 180
150 160 170 180 190
pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
::.. .::. ..:. :::::: ...::. :.:::: .::::.:
NP_852 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
190 200 210 220 230
>>NP_001265840 (OMIM: 605214) calcium-activated potassiu (235 aa)
initn: 532 init1: 339 opt: 534 Z-score: 682.4 bits: 133.3 E(85289): 2.8e-31
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226)
10 20 30
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
.: : : : :: ::. ::..:.::... :.
NP_001 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
10 20 30 40 50 60
40 50 60 70 80
pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
.: :.: :..::::.::.: :....: . . . : :. ::::: .::....
NP_001 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
:. .:::::.: ::.::::: :.. . . :. : .:.. : : :.: :.::.
NP_001 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
130 140 150 160 170 180
150 160 170 180 190
pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
::.. .::. ..:. :::::: ...::. :.:::: .::::.:
NP_001 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
190 200 210 220 230
>>XP_011510627 (OMIM: 605214) PREDICTED: calcium-activat (235 aa)
initn: 532 init1: 339 opt: 534 Z-score: 682.4 bits: 133.3 E(85289): 2.8e-31
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226)
10 20 30
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
.: : : : :: ::. ::..:.::... :.
XP_011 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
10 20 30 40 50 60
40 50 60 70 80
pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
.: :.: :..::::.::.: :....: . . . : :. ::::: .::....
XP_011 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
:. .:::::.: ::.::::: :.. . . :. : .:.. : : :.: :.::.
XP_011 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
130 140 150 160 170 180
150 160 170 180 190
pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
::.. .::. ..:. :::::: ...::. :.:::: .::::.:
XP_011 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
190 200 210 220 230
>>NP_741980 (OMIM: 605222) calcium-activated potassium c (257 aa)
initn: 324 init1: 153 opt: 235 Z-score: 304.2 bits: 63.5 E(85289): 3.3e-10
Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:32-218)
10 20 30 40
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL
:: ::. :: .:. .:. ...: ::.:
NP_741 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
10 20 30 40 50 60
50 60 70 80 90
pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH
.. :. .:: : :.:.: :. .. . .:::: .::.: :. :.:..
NP_741 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR
.:.. . : .: : : .. . .. .. :.... : :: .: .. .:.. .
NP_741 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
130 140 150 160 170 180
160 170 180 190
pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
: .:.. ::::.. : :: ::..::. .:.::.:
NP_741 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
190 200 210 220 230 240
NP_741 FKLCIMRRSKGRAEKS
250
>>NP_741981 (OMIM: 605222) calcium-activated potassium c (275 aa)
initn: 324 init1: 153 opt: 235 Z-score: 303.8 bits: 63.5 E(85289): 3.5e-10
Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:50-236)
10 20 30 40
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL
:: ::. :: .:. .:. ...: ::.:
NP_741 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
20 30 40 50 60 70
50 60 70 80 90
pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH
.. :. .:: : :.:.: :. .. . .:::: .::.: :. :.:..
NP_741 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR
.:.. . : .: : : .. . .. .. :.... : :: .: .. .:.. .
NP_741 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
140 150 160 170 180 190
160 170 180 190
pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
: .:.. ::::.. : :: ::..::. .:.::.:
NP_741 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
200 210 220 230 240 250
NP_741 FKLCIMRRSKGRAEKS
260 270
>>NP_741979 (OMIM: 605222) calcium-activated potassium c (277 aa)
initn: 324 init1: 153 opt: 235 Z-score: 303.8 bits: 63.5 E(85289): 3.5e-10
Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:52-238)
10 20 30 40
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL
:: ::. :: .:. .:. ...: ::.:
NP_741 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH
.. :. .:: : :.:.: :. .. . .:::: .::.: :. :.:..
NP_741 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR
.:.. . : .: : : .. . .. .. :.... : :: .: .. .:.. .
NP_741 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
150 160 170 180 190 200
160 170 180 190
pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
: .:.. ::::.. : :: ::..::. .:.::.:
NP_741 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
210 220 230 240 250 260
NP_741 FKLCIMRRSKGRAEKS
270
>>NP_055222 (OMIM: 605222) calcium-activated potassium c (279 aa)
initn: 324 init1: 153 opt: 235 Z-score: 303.7 bits: 63.5 E(85289): 3.5e-10
Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:54-240)
10 20 30 40
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL
:: ::. :: .:. .:. ...: ::.:
NP_055 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH
.. :. .:: : :.:.: :. .. . .:::: .::.: :. :.:..
NP_055 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR
.:.. . : .: : : .. . .. .. :.... : :: .: .. .:.. .
NP_055 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
150 160 170 180 190 200
160 170 180 190
pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
: .:.. ::::.. : :: ::..::. .:.::.:
NP_055 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
210 220 230 240 250 260
NP_055 FKLCIMRRSKGRAEKS
270
>>NP_055320 (OMIM: 605223) calcium-activated potassium c (210 aa)
initn: 125 init1: 70 opt: 167 Z-score: 219.6 bits: 47.5 E(85289): 1.7e-05
Smith-Waterman score: 191; 22.2% identity (54.7% similar) in 203 aa overlap (1-188:1-201)
10 20 30 40 50
pF1KB6 MVK-KLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLI---
:.: .... ..: ... ::. ... .:.. .:. : ... . :..: ..
NP_055 MAKLRVAYEYTEAEDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQ
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 ------ETNIRDQEELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPG
: .. . .: . ::::. .:: : .. :.:. : : .:::::
NP_055 QIGEVFECTFTCGADCRGTS--QYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPP
70 80 90 100 110
110 120 130 140 150 160
pF1KB6 SVDNYQTARADVEKVRAKFQEQ---QVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPT
. : .: . . .... : : :. . .::..: . .:: ..::
NP_055 CKRENQKNLESVMNWQQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPL
120 130 140 150 160 170
170 180 190
pF1KB6 FLLTGGLLIIAMVKSNQYLSILAAQK
.. :.::.... . :.. :
NP_055 VTFVVGVLIVVLTICAKSLAVKAEAMKKRKFS
180 190 200 210
191 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:56:36 2016 done: Fri Nov 4 14:56:37 2016
Total Scan time: 5.340 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]