Result of FASTA (omim) for
pFN21AB6740
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6740, 142 aa
1>>>pF1KB6740 142 - 142 aa - 142 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7822+/-0.000377; mu= 13.1388+/- 0.023
mean_var=50.8275+/-10.180, 0's: 0 Z-trim(112.1): 17 B-trim: 539 in 1/52
Lambda= 0.179897
statistics sampled from 20919 (20932) to 20919 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.245), width: 16
Scan time: 4.500
The best scores are: opt bits E(85289)
NP_006692 (OMIM: 608572,611595) thioredoxin-like p ( 142) 976 260.9 5e-70
NP_001292486 (OMIM: 608572,611595) thioredoxin-lik ( 134) 905 242.5 1.7e-64
NP_001290400 (OMIM: 608572,611595) thioredoxin-lik ( 103) 614 166.9 7.2e-42
NP_001292492 (OMIM: 608572,611595) thioredoxin-lik ( 71) 487 133.9 4.4e-32
NP_001292493 (OMIM: 608572,611595) thioredoxin-lik ( 71) 487 133.9 4.4e-32
NP_003320 (OMIM: 187700) thioredoxin isoform 1 [Ho ( 105) 115 37.4 0.0071
NP_006532 (OMIM: 612754) glutaredoxin-3 isoform 1 ( 335) 120 38.9 0.0078
NP_001186797 (OMIM: 612754) glutaredoxin-3 isoform ( 335) 120 38.9 0.0078
>>NP_006692 (OMIM: 608572,611595) thioredoxin-like prote (142 aa)
initn: 976 init1: 976 opt: 976 Z-score: 1378.3 bits: 260.9 E(85289): 5e-70
Smith-Waterman score: 976; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KB6 MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVY
70 80 90 100 110 120
130 140
pF1KB6 RGARKGRGLVVSPKDYSTKYRY
::::::::::::::::::::::
NP_006 RGARKGRGLVVSPKDYSTKYRY
130 140
>>NP_001292486 (OMIM: 608572,611595) thioredoxin-like pr (134 aa)
initn: 617 init1: 617 opt: 905 Z-score: 1279.1 bits: 242.5 E(85289): 1.7e-64
Smith-Waterman score: 905; 94.4% identity (94.4% similar) in 142 aa overlap (1-142:1-134)
10 20 30 40 50 60
pF1KB6 MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYL
:::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_001 MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEV--------KNFAVIYL
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 VDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVY
60 70 80 90 100 110
130 140
pF1KB6 RGARKGRGLVVSPKDYSTKYRY
::::::::::::::::::::::
NP_001 RGARKGRGLVVSPKDYSTKYRY
120 130
>>NP_001290400 (OMIM: 608572,611595) thioredoxin-like pr (103 aa)
initn: 614 init1: 614 opt: 614 Z-score: 872.7 bits: 166.9 E(85289): 7.2e-42
Smith-Waterman score: 614; 100.0% identity (100.0% similar) in 91 aa overlap (52-142:13-103)
30 40 50 60 70 80
pF1KB6 EDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTV
::::::::::::::::::::::::::::::
NP_001 MLLARKQILCVNVKNFAVIYLVDITEVPDFNKMYELYDPCTV
10 20 30 40
90 100 110 120 130 140
pF1KB6 MFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYR
50 60 70 80 90 100
pF1KB6 Y
:
NP_001 Y
>>NP_001292492 (OMIM: 608572,611595) thioredoxin-like pr (71 aa)
initn: 487 init1: 487 opt: 487 Z-score: 697.0 bits: 133.9 E(85289): 4.4e-32
Smith-Waterman score: 487; 100.0% identity (100.0% similar) in 71 aa overlap (72-142:1-71)
50 60 70 80 90 100
pF1KB6 DEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNK
::::::::::::::::::::::::::::::
NP_001 MYELYDPCTVMFFFRNKHIMIDLGTGNNNK
10 20 30
110 120 130 140
pF1KB6 INWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY
:::::::::::::::::::::::::::::::::::::::::
NP_001 INWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY
40 50 60 70
>>NP_001292493 (OMIM: 608572,611595) thioredoxin-like pr (71 aa)
initn: 487 init1: 487 opt: 487 Z-score: 697.0 bits: 133.9 E(85289): 4.4e-32
Smith-Waterman score: 487; 100.0% identity (100.0% similar) in 71 aa overlap (72-142:1-71)
50 60 70 80 90 100
pF1KB6 DEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNK
::::::::::::::::::::::::::::::
NP_001 MYELYDPCTVMFFFRNKHIMIDLGTGNNNK
10 20 30
110 120 130 140
pF1KB6 INWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY
:::::::::::::::::::::::::::::::::::::::::
NP_001 INWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY
40 50 60 70
>>NP_003320 (OMIM: 187700) thioredoxin isoform 1 [Homo s (105 aa)
initn: 47 init1: 36 opt: 115 Z-score: 172.6 bits: 37.4 E(85289): 0.0071
Smith-Waterman score: 115; 23.4% identity (60.7% similar) in 107 aa overlap (4-108:1-103)
10 20 30 40 50 60
pF1KB6 MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYL
:. .... ..:. . :..::. :. : : . ..:..:: .: ::.:
NP_003 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSN--VIFL
10 20 30 40 50
70 80 90 100 110
pF1KB6 -VDITEVPDFNKMYELYDPCTVMF-FFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIET
::. . : . :. : : ::.. . . ... .:..:.. ....
NP_003 EVDVDDCQDVASECEV--KCMPTFQFFKKGQKVGEFSGANKEKLEATINELV
60 70 80 90 100
120 130 140
pF1KB6 VYRGARKGRGLVVSPKDYSTKYRY
>>NP_006532 (OMIM: 612754) glutaredoxin-3 isoform 1 [Hom (335 aa)
initn: 46 init1: 46 opt: 120 Z-score: 171.8 bits: 38.9 E(85289): 0.0078
Smith-Waterman score: 120; 24.4% identity (60.3% similar) in 78 aa overlap (13-90:21-97)
10 20 30 40 50
pF1KB6 MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKV
: .. . . ..:..: : : : .:.::. .:...
NP_006 MAAGAAEAAVAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEM
. . . : . ::. .. ::. . : .:: ...:
NP_006 PQVSFVKL-EAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSG
70 80 90 100 110
120 130 140
pF1KB6 VDIIETVYRGARKGRGLVVSPKDYSTKYRY
NP_006 SFLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSF
120 130 140 150 160 170
>>NP_001186797 (OMIM: 612754) glutaredoxin-3 isoform 1 [ (335 aa)
initn: 46 init1: 46 opt: 120 Z-score: 171.8 bits: 38.9 E(85289): 0.0078
Smith-Waterman score: 120; 24.4% identity (60.3% similar) in 78 aa overlap (13-90:21-97)
10 20 30 40 50
pF1KB6 MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKV
: .. . . ..:..: : : : .:.::. .:...
NP_001 MAAGAAEAAVAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKEL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEM
. . . : . ::. .. ::. . : .:: ...:
NP_001 PQVSFVKL-EAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSG
70 80 90 100 110
120 130 140
pF1KB6 VDIIETVYRGARKGRGLVVSPKDYSTKYRY
NP_001 SFLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSF
120 130 140 150 160 170
142 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:31:43 2016 done: Fri Nov 4 15:31:44 2016
Total Scan time: 4.500 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]