Result of FASTA (ccds) for
pFN21AB6476
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6476, 355 aa
1>>>pF1KB6476 355 - 355 aa - 355 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4080+/-0.00117; mu= 6.7114+/- 0.069
mean_var=146.1146+/-29.874, 0's: 0 Z-trim(106.0): 152 B-trim: 32 in 1/52
Lambda= 0.106103
statistics sampled from 8536 (8707) to 8536 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.267), width: 16
Scan time: 2.490
The best scores are: opt bits E(32554)
CCDS73772.1 SH3GL3 gene_id:6457|Hs108|chr15 ( 355) 2321 367.3 1.1e-101
CCDS10325.2 SH3GL3 gene_id:6457|Hs108|chr15 ( 347) 2162 342.9 2.3e-94
CCDS6483.1 SH3GL2 gene_id:6456|Hs108|chr9 ( 352) 1532 246.5 2.5e-65
CCDS32874.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 368) 1184 193.2 2.9e-49
CCDS56076.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 320) 708 120.3 2.2e-27
CCDS59335.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 304) 545 95.4 6.9e-20
>>CCDS73772.1 SH3GL3 gene_id:6457|Hs108|chr15 (355 aa)
initn: 2321 init1: 2321 opt: 2321 Z-score: 1938.9 bits: 367.3 E(32554): 1.1e-101
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ
310 320 330 340 350
>>CCDS10325.2 SH3GL3 gene_id:6457|Hs108|chr15 (347 aa)
initn: 2162 init1: 2162 opt: 2162 Z-score: 1807.5 bits: 342.9 E(32554): 2.3e-94
Smith-Waterman score: 2162; 99.4% identity (100.0% similar) in 335 aa overlap (21-355:13-347)
10 20 30 40 50 60
pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
..::::::::::::::::::::::::::::::::::::::
CCDS10 MSVAGLKKQFHKASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG
240 250 260 270 280 290
310 320 330 340 350
pF1KB6 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ
300 310 320 330 340
>>CCDS6483.1 SH3GL2 gene_id:6456|Hs108|chr9 (352 aa)
initn: 1554 init1: 1124 opt: 1532 Z-score: 1286.2 bits: 246.5 E(32554): 2.5e-65
Smith-Waterman score: 1532; 67.1% identity (87.1% similar) in 340 aa overlap (23-355:15-352)
10 20 30 40 50 60
pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
: :::..:::::::::.: .::::.:::...: ::..
CCDS64 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
:: :::::::: ::::.:.::.:::::: : ::::.:.::.. :::.:.:::.: .::
CCDS64 KTIEYLQPNPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
:: ::::.:. ..::::::::.:::.:::::: :.::::.:: ::::::::::::.::::
CCDS64 ALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
:: :::::::.:::.:::.::::.:: ::::.:: :.::::::.....: :.::.:...:
CCDS64 KRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQI
180 190 200 210 220 230
250 260 270 280 290
pF1KB6 LQELQSKLQMRISAASSVPRREYKPRP-------VKRSSSELNGVSTTSVVKTTGSNIPM
::.. .:. :: ::: :::::.:.: . :.. .:.: :.. : .: . :
CCDS64 LQQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSG--VQM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 DQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPL
::::::.::::::::.:::::::::::::::::::::::::.::.::::::::::..: :
CCDS64 DQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVEILVAL
300 310 320 330 340 350
pF1KB6 PQ
:.
CCDS64 PH
>>CCDS32874.1 SH3GL1 gene_id:6455|Hs108|chr19 (368 aa)
initn: 1562 init1: 1184 opt: 1184 Z-score: 998.0 bits: 193.2 E(32554): 2.9e-49
Smith-Waterman score: 1528; 64.7% identity (84.4% similar) in 360 aa overlap (19-355:11-368)
10 20 30 40 50 60
pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
. ..:: :::..:::::::::.: .::.:.:::.:.:.:.:.
CCDS32 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
.: :::::::: :::: :::::::::::::. ::::.:::::.::...::::: .:.::.
CCDS32 RTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
::...::::: .:::::::::.:::.:::::: : .:::::: ::::::::::::.::::
CCDS32 ALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
:: :::::::.:::.::::::::.:: :: :.::.:.::::::.....: ::::::...:
CCDS32 KRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQI
180 190 200 210 220 230
250 260 270 280
pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSEL------NG---------VSTTSVVK
:.:: ::. :. ::: :.:::::.: : .: :: ....: .
CCDS32 LDELAEKLKRRMREASSRPKREYKPKP--REPFDLGEPEQSNGGFPCTTAPKIAASSSFR
240 250 260 270 280 290
290 300 310 320 330
pF1KB6 TTGSNI--------PMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHG
.. . : :.::: :..::::::::.:::::.:::.:::::::::::::::. :
CCDS32 SSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDG
300 310 320 330 340 350
340 350
pF1KB6 ESGFFPINYVEVIVPLPQ
.:::::..::::.:::::
CCDS32 QSGFFPLSYVEVLVPLPQ
360
>>CCDS56076.1 SH3GL1 gene_id:6455|Hs108|chr19 (320 aa)
initn: 1306 init1: 708 opt: 708 Z-score: 605.1 bits: 120.3 E(32554): 2.2e-27
Smith-Waterman score: 1180; 54.7% identity (72.2% similar) in 360 aa overlap (19-355:11-320)
10 20 30 40 50 60
pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
. ..:: :::..:::::::::.: .::.:.:::.:.:.:.:.
CCDS56 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
.: ::::::: :.
CCDS56 RTIEYLQPNP------------------------------------------------GD
60
130 140 150 160 170 180
pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
::...::::: .:::::::::.:::.:::::: : .:::::: ::::::::::::.::::
CCDS56 ALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKK
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
:: :::::::.:::.::::::::.:: :: :.::.:.::::::.....: ::::::...:
CCDS56 KRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQI
130 140 150 160 170 180
250 260 270 280
pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSEL------NG---------VSTTSVVK
:.:: ::. :. ::: :.:::::.: : .: :: ....: .
CCDS56 LDELAEKLKRRMREASSRPKREYKPKP--REPFDLGEPEQSNGGFPCTTAPKIAASSSFR
190 200 210 220 230 240
290 300 310 320 330
pF1KB6 TTGSNI--------PMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHG
.. . : :.::: :..::::::::.:::::.:::.:::::::::::::::. :
CCDS56 SSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDG
250 260 270 280 290 300
340 350
pF1KB6 ESGFFPINYVEVIVPLPQ
.:::::..::::.:::::
CCDS56 QSGFFPLSYVEVLVPLPQ
310 320
>>CCDS59335.1 SH3GL1 gene_id:6455|Hs108|chr19 (304 aa)
initn: 923 init1: 545 opt: 545 Z-score: 470.6 bits: 95.4 E(32554): 6.9e-20
Smith-Waterman score: 1070; 51.9% identity (67.8% similar) in 360 aa overlap (19-355:11-304)
10 20 30 40 50 60
pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
. ..:: :::..:::::::::.: .::.:.:::.:.:.:.:.
CCDS59 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
.: :::::::: :::: ::::::::::: . :
CCDS59 RTIEYLQPNPASRAKLTMLNTVSKIRGQ-------------NLC----------------
60 70 80
130 140 150 160 170 180
pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
.:::::: ::::::::::::.::::
CCDS59 -----------------------------------EKDLKEIQHHLKKLEGRRLDFDYKK
90 100
190 200 210 220 230 240
pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
:: :::::::.:::.::::::::.:: :: :.::.:.::::::.....: ::::::...:
CCDS59 KRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQI
110 120 130 140 150 160
250 260 270 280
pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSEL------NG---------VSTTSVVK
:.:: ::. :. ::: :.:::::.: : .: :: ....: .
CCDS59 LDELAEKLKRRMREASSRPKREYKPKP--REPFDLGEPEQSNGGFPCTTAPKIAASSSFR
170 180 190 200 210 220
290 300 310 320 330
pF1KB6 TTGSNI--------PMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHG
.. . : :.::: :..::::::::.:::::.:::.:::::::::::::::. :
CCDS59 SSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDG
230 240 250 260 270 280
340 350
pF1KB6 ESGFFPINYVEVIVPLPQ
.:::::..::::.:::::
CCDS59 QSGFFPLSYVEVLVPLPQ
290 300
355 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:26:14 2016 done: Fri Nov 4 16:26:14 2016
Total Scan time: 2.490 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]