Result of FASTA (omim) for
pFN21AB6430
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6430, 343 aa
1>>>pF1KB6430 343 - 343 aa - 343 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1697+/-0.000371; mu= 17.4336+/- 0.023
mean_var=78.3649+/-16.184, 0's: 0 Z-trim(114.6): 147 B-trim: 1114 in 2/50
Lambda= 0.144882
statistics sampled from 24356 (24526) to 24356 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.288), width: 16
Scan time: 8.010
The best scores are: opt bits E(85289)
XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 2355 501.8 9e-142
NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 2320 494.4 1.4e-139
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 1968 420.9 2.1e-117
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 1941 415.3 1.1e-115
XP_016885777 (OMIM: 142800,608579) PREDICTED: HLA ( 362) 1897 406.1 6.2e-113
XP_005275388 (OMIM: 142800,608579) PREDICTED: HLA ( 391) 1897 406.1 6.5e-113
NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 1891 404.8 1.5e-112
NP_001229971 (OMIM: 142840,177900,609423) HLA clas ( 366) 1865 399.4 6.4e-111
NP_002108 (OMIM: 142840,177900,609423) HLA class I ( 366) 1856 397.5 2.4e-110
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 1841 394.3 2e-109
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 1841 394.4 2.2e-109
XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 1841 394.4 2.3e-109
XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 1841 394.4 2.4e-109
NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 1841 394.4 2.4e-109
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 1833 392.7 6.3e-109
XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 1833 392.7 7.5e-109
NP_005507 (OMIM: 143010) HLA class I histocompatib ( 358) 1812 388.3 1.4e-107
XP_016866298 (OMIM: 143010) PREDICTED: HLA class I ( 359) 1812 388.3 1.4e-107
XP_011512859 (OMIM: 106300,142830,608579) PREDICTE ( 323) 1742 373.6 3.2e-103
XP_016866296 (OMIM: 143010) PREDICTED: HLA class I ( 399) 1734 372.0 1.2e-102
XP_016866297 (OMIM: 143010) PREDICTED: HLA class I ( 399) 1734 372.0 1.2e-102
XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 1235 267.5 2e-71
XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 1235 267.6 2.6e-71
NP_001091948 (OMIM: 143110) HLA class I histocompa ( 254) 1033 225.3 1.1e-58
XP_016866307 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 910 199.6 5.9e-51
XP_016866306 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 910 199.6 5.9e-51
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 796 175.9 1.1e-43
NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 718 159.6 8.9e-39
NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 718 159.6 9.2e-39
XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 718 159.6 9.2e-39
NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 677 151.0 3.3e-36
NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 658 147.0 4.9e-35
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 593 133.4 5.3e-31
NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 558 126.1 8.6e-29
NP_001170990 (OMIM: 600169) MHC class I polypeptid ( 332) 508 115.7 1.4e-25
NP_000238 (OMIM: 600169) MHC class I polypeptide-r ( 383) 491 112.2 1.9e-24
NP_001181929 (OMIM: 600764) major histocompatibili ( 249) 486 111.0 2.8e-24
NP_001181964 (OMIM: 600764) major histocompatibili ( 214) 485 110.7 2.9e-24
NP_005922 (OMIM: 602436) MHC class I polypeptide-r ( 383) 464 106.5 9.4e-23
NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 436 100.6 4.5e-21
NP_001276089 (OMIM: 602436) MHC class I polypeptid ( 351) 433 100.0 7.9e-21
NP_004098 (OMIM: 601437) IgG receptor FcRn large s ( 365) 415 96.3 1.1e-19
NP_001129491 (OMIM: 601437) IgG receptor FcRn larg ( 365) 415 96.3 1.1e-19
NP_001276082 (OMIM: 600169) MHC class I polypeptid ( 235) 363 85.3 1.5e-16
NP_001276081 (OMIM: 600169) MHC class I polypeptid ( 235) 363 85.3 1.5e-16
NP_620573 (OMIM: 104300,176100,176200,235200,61263 ( 256) 360 84.7 2.4e-16
NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 352 82.8 5.7e-16
NP_001297142 (OMIM: 600764) major histocompatibili ( 178) 334 79.1 8e-15
NP_001307581 (OMIM: 188370) T-cell surface glycopr ( 316) 332 78.9 1.7e-14
NP_001754 (OMIM: 188370) T-cell surface glycoprote ( 327) 332 78.9 1.7e-14
>>XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA clas (343 aa)
initn: 2355 init1: 2355 opt: 2355 Z-score: 2666.2 bits: 501.8 E(85289): 9e-142
Smith-Waterman score: 2355; 100.0% identity (100.0% similar) in 343 aa overlap (1-343:1-343)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
250 260 270 280 290 300
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
:::::::::::::::::::::::::::::::::::::::::::
XP_016 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
310 320 330 340
>>NP_002118 (OMIM: 142871,600807) HLA class I histocompa (338 aa)
initn: 2320 init1: 2320 opt: 2320 Z-score: 2626.8 bits: 494.4 E(85289): 1.4e-139
Smith-Waterman score: 2320; 100.0% identity (100.0% similar) in 338 aa overlap (6-343:1-338)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
:::::::::::::::::::::::::::::::::::::::::::
NP_002 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
300 310 320 330
>>NP_002107 (OMIM: 142800,608579) HLA class I histocompa (365 aa)
initn: 1968 init1: 1968 opt: 1968 Z-score: 2228.7 bits: 420.9 E(85289): 2.1e-117
Smith-Waterman score: 1968; 82.8% identity (95.0% similar) in 338 aa overlap (6-343:1-338)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
:.:::::::.:::::::.::.::::::::::: ..:::::::::::::.::::::
NP_002 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::.: ::::::::.::::::::..::::.::..::::..: :::::::::::.
NP_002 QFVRFDSDAASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
:::.: : :::.:::::.::::.: :::::::.::::::::::::: ::::.::: :::.
NP_002 SHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
::: ::::.:::::::.:::::::: :::.::::::.::::. :.::::::::::::::
NP_002 EAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
:: :::::::::::::.:::::::::::::::::::::::::::::::::::::::.::
NP_002 EITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLT
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
:::. :: :::::.::.::::.:.::.:::.::::.::.::::
NP_002 LRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQG
300 310 320 330 340 350
NP_002 SDVSLTACKV
360
>>NP_001229687 (OMIM: 142800,608579) HLA class I histoco (365 aa)
initn: 1941 init1: 1941 opt: 1941 Z-score: 2198.2 bits: 415.3 E(85289): 1.1e-115
Smith-Waterman score: 1941; 81.7% identity (93.8% similar) in 338 aa overlap (6-343:1-338)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
:.:::::::.:::::::.::.::::::::::: ..:::::::::::::.::::::
NP_001 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::.: .:::::::.::::::::..:::: :::.:::: :: :::::::::: .
NP_001 QFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
:::.: : :::.: :::.::::.: :::::::.::::::::::::: ::::.::: ::..
NP_001 SHTIQIMYGCDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAVH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
.:::::.:::: ::. :.:::::::: :::.::::::.::::. :.::::::::::::::
NP_001 AAEQRRVYLEGRCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
:: :::::::::::::.:::::::::::::::::::::::::::::::::::::::.::
NP_001 EITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLT
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
:::. :: :::::.::.::::.:.::.:::.::::.::.::::
NP_001 LRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQG
300 310 320 330 340 350
NP_001 SDVSLTACKV
360
>>XP_016885777 (OMIM: 142800,608579) PREDICTED: HLA clas (362 aa)
initn: 1897 init1: 1897 opt: 1897 Z-score: 2148.5 bits: 406.1 E(85289): 6.2e-113
Smith-Waterman score: 1897; 81.2% identity (93.4% similar) in 335 aa overlap (9-343:1-335)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
:::::: :::::::.::.::::::::::: ..:::::::::::::.::::::
XP_016 MAPRTLVLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::.: ::::::::.::::::::. :::..:::.:: :..: :::::::::::.
XP_016 QFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
:::.: : :::.::: :.::::.:::::::::.::.:::::::::: ::: .:.: :::.
XP_016 SHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
:::: ::::::::::::.:::::::: :::.: ::::.::: : :.:::::::::.::::
XP_016 VAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
:: :::::::::::::.::::::::::::::::::::::::.::::::::::::::.::
XP_016 EITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLT
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
:::. :: :::::.::.::::...::.:::.::::.::.::::
XP_016 LRWEPSSQPTIPIVGIIAGLVLFGAVITGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQG
300 310 320 330 340 350
XP_016 SDVSLTACKV
360
>>XP_005275388 (OMIM: 142800,608579) PREDICTED: HLA clas (391 aa)
initn: 1897 init1: 1897 opt: 1897 Z-score: 2148.1 bits: 406.1 E(85289): 6.5e-113
Smith-Waterman score: 1897; 81.2% identity (93.4% similar) in 335 aa overlap (9-343:1-335)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
:::::: :::::::.::.::::::::::: ..:::::::::::::.::::::
XP_005 MAPRTLVLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::.: ::::::::.::::::::. :::..:::.:: :..: :::::::::::.
XP_005 QFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
:::.: : :::.::: :.::::.:::::::::.::.:::::::::: ::: .:.: :::.
XP_005 SHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
:::: ::::::::::::.:::::::: :::.: ::::.::: : :.:::::::::.::::
XP_005 VAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
:: :::::::::::::.::::::::::::::::::::::::.::::::::::::::.::
XP_005 EITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLT
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
:::. :: :::::.::.::::...::.:::.::::.::.::::
XP_005 LRWEPSSQPTIPIVGIIAGLVLFGAVITGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQG
300 310 320 330 340 350
XP_005 SDVSLTACKGESLEGLMCVGCWAEQWTQLCYGVSFHWMY
360 370 380 390
>>NP_005505 (OMIM: 106300,142830,608579) major histocomp (362 aa)
initn: 1891 init1: 1891 opt: 1891 Z-score: 2141.8 bits: 404.8 E(85289): 1.5e-112
Smith-Waterman score: 1891; 81.0% identity (93.2% similar) in 337 aa overlap (6-342:1-337)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
:.::::::..::::.::.:::::::::::::: ..::::::::::::..::::::
NP_005 MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::.: :: ::::::.::::::::...:. ::.::::: .:..::::::::::.
NP_005 QFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
::::: : :::.: :::::::..:::::::::.::::::::::::::::::..:: :::
NP_005 SHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
:::::::::: :::::.:::::::. :.:::::::::::::. :.::::::::::::::
NP_005 EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
:: :::::::::::::.:::::::::: ::::::::::::::::::::::::::::.::
NP_005 EITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLT
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
:::. :: :.::.::::::.:::.:: ::.::::. :.:::
NP_005 LRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQG
300 310 320 330 340 350
NP_005 SDVSLTA
360
>>NP_001229971 (OMIM: 142840,177900,609423) HLA class I (366 aa)
initn: 1907 init1: 1830 opt: 1865 Z-score: 2112.3 bits: 399.4 E(85289): 6.4e-111
Smith-Waterman score: 1865; 80.5% identity (92.6% similar) in 338 aa overlap (6-342:1-338)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
: :::::.:.:::::.:.:::::: :::::::..:::::::::::::..::::::
NP_001 MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::.: :: :::::::::::::::..::.: : .::.::..:..::::::::: .
NP_001 QFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQNYKRQAQADRVSLRNLRGYYNQSEDG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
::::: : ::::: ::::::::.: :::::::.::::::::::::::::::..:: :::
NP_001 SHTLQRMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
.::: ::::::::::::.:::::::: ::::.::::::::::. :.::::::::::::::
NP_001 AAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
:: :::::::::::::.::::::::::::::::::::::::.:::::::.::::: :::
NP_001 EITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLT
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAV-VTGAAVAAVLWRKKSSD
: :. :: ::::::::::::.::... : ::.:.:.. :.:::
NP_001 LSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQ
300 310 320 330 340 350
NP_001 GSDESLITCKA
360
>>NP_002108 (OMIM: 142840,177900,609423) HLA class I his (366 aa)
initn: 1898 init1: 1821 opt: 1856 Z-score: 2102.2 bits: 397.5 E(85289): 2.4e-110
Smith-Waterman score: 1856; 80.2% identity (92.6% similar) in 338 aa overlap (6-342:1-338)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
: :::::.:.:::::.:.:::::: :::::::..:::::::::::::..::::::
NP_002 MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::::::::.: :: :::::::::::::::..::.. : .::.::..:..::::::::: .
NP_002 QFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
::::: : ::::: ::::::::.: :::::::.::::::::::::::::::..:: :::
NP_002 SHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
.::: ::::::::::::.:::::::: ::::.::::::::::. :.::::::::::::::
NP_002 AAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
:: :::::::::::::.::::::::::::::::::::::::.:::::::.::::: :::
NP_002 EITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLT
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAV-VTGAAVAAVLWRKKSSD
: :. :: ::::::::::::.::... : ::.:.:.. :.:::
NP_002 LSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQ
300 310 320 330 340 350
NP_002 GSDESLITCKA
360
>>NP_061823 (OMIM: 143110) HLA class I histocompatibilit (346 aa)
initn: 1841 init1: 1841 opt: 1841 Z-score: 2085.5 bits: 394.3 E(85289): 2e-109
Smith-Waterman score: 1841; 79.1% identity (91.9% similar) in 335 aa overlap (9-343:1-335)
10 20 30 40 50 60
pF1KB6 MKTPRMVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDT
::::.:.:::::::.::.:::::::.::::.:::::::::::.::. :::::
NP_061 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDT
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFVRFDSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEAS
::.:::::.: :::::: ::::::::.::: : .::.:::::. :..: ::::::.
NP_061 QFLRFDSDAAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 SHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAAN
::::: : :::.: ::::::::.:.:::::::..:::::::::::::.:::..: :: .
NP_061 SHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 VAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPA
::. :.:::: :.: :.:::::::: ::::::::.::.:::. :.::::::::::::::
NP_061 YAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 EIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLM
:: ::::::::.::::.:::::::::::::::::::::: ::::::::::::::::.::.
NP_061 EITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLI
240 250 260 270 280 290
310 320 330 340
pF1KB6 LRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD
:::.:: :::::.:::::::::.::::::.::::.:::::::
NP_061 LRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV
300 310 320 330 340
343 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:45:26 2016 done: Fri Nov 4 16:45:28 2016
Total Scan time: 8.010 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]