Result of FASTA (omim) for
pFN21AB6518
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6518, 386 aa
1>>>pF1KB6518 386 - 386 aa - 386 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5757+/-0.000306; mu= 6.9971+/- 0.019
mean_var=147.8779+/-30.517, 0's: 0 Z-trim(122.1): 323 B-trim: 1529 in 2/59
Lambda= 0.105468
statistics sampled from 39143 (39602) to 39143 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.464), width: 16
Scan time: 9.490
The best scores are: opt bits E(85289)
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 2626 410.8 2.8e-114
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 2626 410.8 2.8e-114
XP_006723402 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 2626 410.8 2.8e-114
NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 ( 386) 2626 410.8 2.8e-114
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385) 2607 407.9 2.1e-113
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383) 2030 320.1 5.6e-87
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382) 2011 317.2 4.1e-86
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422) 1616 257.1 5.6e-68
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422) 1616 257.1 5.6e-68
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422) 1616 257.1 5.6e-68
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479) 1616 257.1 6.2e-68
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419) 1614 256.8 6.8e-68
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419) 1614 256.8 6.8e-68
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419) 1614 256.8 6.8e-68
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476) 1614 256.8 7.6e-68
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419) 1593 253.6 6.3e-67
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 1593 253.6 6.3e-67
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 1593 253.6 6.3e-67
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 1587 252.7 1.2e-66
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 1587 252.7 1.2e-66
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422) 1587 252.7 1.2e-66
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 1587 252.7 1.2e-66
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 1587 252.7 1.2e-66
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo ( 425) 972 159.1 1.8e-38
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425) 972 159.1 1.8e-38
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443) 972 159.1 1.8e-38
NP_783860 (OMIM: 613528) synaptotagmin-9 [Homo sap ( 491) 940 154.3 5.8e-37
XP_011518206 (OMIM: 613528) PREDICTED: synaptotagm ( 492) 940 154.3 5.8e-37
XP_011518204 (OMIM: 613528) PREDICTED: synaptotagm ( 535) 940 154.3 6.2e-37
XP_011518203 (OMIM: 613528) PREDICTED: synaptotagm ( 564) 940 154.3 6.5e-37
XP_011518202 (OMIM: 613528) PREDICTED: synaptotagm ( 567) 940 154.3 6.5e-37
NP_001153800 (OMIM: 600327) synaptotagmin-3 [Homo ( 590) 908 149.5 2e-35
XP_011525693 (OMIM: 600327) PREDICTED: synaptotagm ( 590) 908 149.5 2e-35
NP_001153801 (OMIM: 600327) synaptotagmin-3 [Homo ( 590) 908 149.5 2e-35
XP_011525692 (OMIM: 600327) PREDICTED: synaptotagm ( 590) 908 149.5 2e-35
NP_115674 (OMIM: 600327) synaptotagmin-3 [Homo sap ( 590) 908 149.5 2e-35
XP_006718799 (OMIM: 604146) PREDICTED: synaptotagm ( 293) 894 147.1 4.9e-35
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403) 894 147.2 6.3e-35
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409) 894 147.2 6.4e-35
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447) 894 147.3 6.9e-35
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449) 894 147.3 6.9e-35
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453) 894 147.3 6.9e-35
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478) 894 147.3 7.2e-35
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484) 894 147.3 7.3e-35
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528) 894 147.3 7.8e-35
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611) 894 147.4 8.8e-35
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617) 894 147.4 8.9e-35
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642) 894 147.4 9.2e-35
XP_011543639 (OMIM: 604146) PREDICTED: synaptotagm ( 648) 894 147.4 9.2e-35
XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651) 894 147.4 9.3e-35
>>XP_016882665 (OMIM: 600782) PREDICTED: synaptotagmin-5 (386 aa)
initn: 2626 init1: 2626 opt: 2626 Z-score: 2172.6 bits: 410.8 E(85289): 2.8e-114
Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
310 320 330 340 350 360
370 380
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
::::::::::::::::::::::::::
XP_016 LANPRRPIAQWHSLRPPDRVRLLPAP
370 380
>>XP_016882664 (OMIM: 600782) PREDICTED: synaptotagmin-5 (386 aa)
initn: 2626 init1: 2626 opt: 2626 Z-score: 2172.6 bits: 410.8 E(85289): 2.8e-114
Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
310 320 330 340 350 360
370 380
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
::::::::::::::::::::::::::
XP_016 LANPRRPIAQWHSLRPPDRVRLLPAP
370 380
>>XP_006723402 (OMIM: 600782) PREDICTED: synaptotagmin-5 (386 aa)
initn: 2626 init1: 2626 opt: 2626 Z-score: 2172.6 bits: 410.8 E(85289): 2.8e-114
Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
310 320 330 340 350 360
370 380
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
::::::::::::::::::::::::::
XP_006 LANPRRPIAQWHSLRPPDRVRLLPAP
370 380
>>NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 [Ho (386 aa)
initn: 2626 init1: 2626 opt: 2626 Z-score: 2172.6 bits: 410.8 E(85289): 2.8e-114
Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
310 320 330 340 350 360
370 380
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
::::::::::::::::::::::::::
NP_003 LANPRRPIAQWHSLRPPDRVRLLPAP
370 380
>>XP_006723403 (OMIM: 600782) PREDICTED: synaptotagmin-5 (385 aa)
initn: 1626 init1: 1626 opt: 2607 Z-score: 2157.0 bits: 407.9 E(85289): 2.1e-113
Smith-Waterman score: 2607; 99.7% identity (99.7% similar) in 386 aa overlap (1-386:1-385)
10 20 30 40 50 60
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_006 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREE-EKL
190 200 210 220 230
250 260 270 280 290 300
pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM
300 310 320 330 340 350
370 380
pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP
::::::::::::::::::::::::::
XP_006 LANPRRPIAQWHSLRPPDRVRLLPAP
360 370 380
>>XP_006723404 (OMIM: 600782) PREDICTED: synaptotagmin-5 (383 aa)
initn: 2046 init1: 2025 opt: 2030 Z-score: 1682.5 bits: 320.1 E(85289): 5.6e-87
Smith-Waterman score: 2030; 84.1% identity (88.9% similar) in 377 aa overlap (17-386:7-383)
10 20 30 40 50
pF1KB6 MFPEPPTPGPPSPDTPPDSSRI-SHGPVPPWALATIVLVSGLLIFS----CCFCLYRKSC
: :.:. .. : :. : ..: : . :: ::.
XP_006 MTRGGCPVSARLFAQRPHGSWSSLLCVGLKGRLGWEWGTRVLECLCRKDS
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 RRRT--GKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQ
: ... : .. . .. : .:::::::::::::::::::::::::::::
XP_006 RTPPPCSRSPQPRGLHRPTRLPTPVASATAQVQPEVEELEPAPSGPGQQVADKHELGRLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG
300 310 320 330 340 350
360 370 380
pF1KB6 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
:::::::::::::::::::::::::::::::::
XP_006 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
360 370 380
>>NP_001284703 (OMIM: 600782) synaptotagmin-5 isoform 2 (382 aa)
initn: 1046 init1: 1025 opt: 2011 Z-score: 1666.9 bits: 317.2 E(85289): 4.1e-86
Smith-Waterman score: 2011; 83.8% identity (88.6% similar) in 377 aa overlap (17-386:7-382)
10 20 30 40 50
pF1KB6 MFPEPPTPGPPSPDTPPDSSRI-SHGPVPPWALATIVLVSGLLIFS----CCFCLYRKSC
: :.:. .. : :. : ..: : . :: ::.
NP_001 MTRGGCPVSARLFAQRPHGSWSSLLCVGLKGRLGWEWGTRVLECLCRKDS
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 RRRT--GKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQ
: ... : .. . .. : .:::::::::::::::::::::::::::::
NP_001 RTPPPCSRSPQPRGLHRPTRLPTPVASATAQVQPEVEELEPAPSGPGQQVADKHELGRLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REE-EKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK
240 250 260 270 280
300 310 320 330 340 350
pF1KB6 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG
290 300 310 320 330 340
360 370 380
pF1KB6 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
:::::::::::::::::::::::::::::::::
NP_001 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
350 360 370 380
>>XP_011507494 (OMIM: 600104,616040) PREDICTED: synaptot (422 aa)
initn: 1829 init1: 1436 opt: 1616 Z-score: 1341.5 bits: 257.1 E(85289): 5.6e-68
Smith-Waterman score: 1616; 61.6% identity (86.8% similar) in 365 aa overlap (20-383:53-417)
10 20 30 40
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFC
..:.. :.::::: .:..:.:::...::::
XP_011 PIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPWALIAIAVVAGLLLLTCCFC
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB6 LYRKSC-RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
. .: : ... .:: ..... . ...: . . . . . ..: : :.. . ..
XP_011 ICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQLPQDDDDAETGLTEGEGEGEEEKEPEN
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB6 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT
::.::.:::::::..:: ::.::: : :::.::.:::::.:.:::::...:::::::.:
XP_011 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB6 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRE
::: :.:::.::::: ::::..::::.:::::::..: ::::.:::..::::.:.. ::.
XP_011 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRD
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 LQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGK
::.. .:: ::::::: ::::::::::::: .::::::::::::::::::::.::.:.::
XP_011 LQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGK
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB6 KVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAA
...:::::.::.:::::.::.::::.: .:.::::: .:::::::::::::::.. ::.
XP_011 RLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSN
330 340 350 360 370 380
350 360 370 380
pF1KB6 AGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
: :. ::::.::::::::::::::::.: ..: :
XP_011 ATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
390 400 410 420
>>XP_016855800 (OMIM: 600104,616040) PREDICTED: synaptot (422 aa)
initn: 1829 init1: 1436 opt: 1616 Z-score: 1341.5 bits: 257.1 E(85289): 5.6e-68
Smith-Waterman score: 1616; 61.6% identity (86.8% similar) in 365 aa overlap (20-383:53-417)
10 20 30 40
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFC
..:.. :.::::: .:..:.:::...::::
XP_016 PIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPWALIAIAVVAGLLLLTCCFC
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB6 LYRKSC-RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
. .: : ... .:: ..... . ...: . . . . . ..: : :.. . ..
XP_016 ICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQLPQDDDDAETGLTEGEGEGEEEKEPEN
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB6 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT
::.::.:::::::..:: ::.::: : :::.::.:::::.:.:::::...:::::::.:
XP_016 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB6 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRE
::: :.:::.::::: ::::..::::.:::::::..: ::::.:::..::::.:.. ::.
XP_016 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRD
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 LQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGK
::.. .:: ::::::: ::::::::::::: .::::::::::::::::::::.::.:.::
XP_016 LQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGK
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB6 KVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAA
...:::::.::.:::::.::.::::.: .:.::::: .:::::::::::::::.. ::.
XP_016 RLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSN
330 340 350 360 370 380
350 360 370 380
pF1KB6 AGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
: :. ::::.::::::::::::::::.: ..: :
XP_016 ATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
390 400 410 420
>>XP_016855801 (OMIM: 600104,616040) PREDICTED: synaptot (422 aa)
initn: 1829 init1: 1436 opt: 1616 Z-score: 1341.5 bits: 257.1 E(85289): 5.6e-68
Smith-Waterman score: 1616; 61.6% identity (86.8% similar) in 365 aa overlap (20-383:53-417)
10 20 30 40
pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFC
..:.. :.::::: .:..:.:::...::::
XP_016 PIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPWALIAIAVVAGLLLLTCCFC
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB6 LYRKSC-RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
. .: : ... .:: ..... . ...: . . . . . ..: : :.. . ..
XP_016 ICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQLPQDDDDAETGLTEGEGEGEEEKEPEN
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB6 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT
::.::.:::::::..:: ::.::: : :::.::.:::::.:.:::::...:::::::.:
XP_016 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB6 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRE
::: :.:::.::::: ::::..::::.:::::::..: ::::.:::..::::.:.. ::.
XP_016 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRD
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 LQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGK
::.. .:: ::::::: ::::::::::::: .::::::::::::::::::::.::.:.::
XP_016 LQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGK
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB6 KVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAA
...:::::.::.:::::.::.::::.: .:.::::: .:::::::::::::::.. ::.
XP_016 RLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSN
330 340 350 360 370 380
350 360 370 380
pF1KB6 AGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
: :. ::::.::::::::::::::::.: ..: :
XP_016 ATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
390 400 410 420
386 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:09:07 2016 done: Fri Nov 4 17:09:08 2016
Total Scan time: 9.490 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]