Result of FASTA (ccds) for
pFN21AB5771
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5771, 733 aa
1>>>pF1KB5771 733 - 733 aa - 733 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5224+/-0.00133; mu= -5.2101+/- 0.077
mean_var=402.8678+/-93.591, 0's: 0 Z-trim(109.5): 451 B-trim: 1269 in 2/51
Lambda= 0.063899
statistics sampled from 10349 (10903) to 10349 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.335), width: 16
Scan time: 4.150
The best scores are: opt bits E(32554)
CCDS43730.1 FGFR1 gene_id:2260|Hs108|chr8 ( 733) 4987 475.3 1.5e-133
CCDS43731.1 FGFR1 gene_id:2260|Hs108|chr8 ( 731) 4959 472.7 8.9e-133
CCDS6107.2 FGFR1 gene_id:2260|Hs108|chr8 ( 822) 4765 454.9 2.3e-127
CCDS55221.1 FGFR1 gene_id:2260|Hs108|chr8 ( 812) 4741 452.6 1.1e-126
CCDS55222.1 FGFR1 gene_id:2260|Hs108|chr8 ( 820) 4741 452.6 1.1e-126
CCDS43732.1 FGFR1 gene_id:2260|Hs108|chr8 ( 820) 4737 452.3 1.4e-126
CCDS55223.1 FGFR1 gene_id:2260|Hs108|chr8 ( 853) 4737 452.3 1.4e-126
CCDS73210.1 FGFR2 gene_id:2263|Hs108|chr10 ( 732) 3803 366.1 1.1e-100
CCDS31298.1 FGFR2 gene_id:2263|Hs108|chr10 ( 821) 3754 361.6 2.7e-99
CCDS81515.1 FGFR2 gene_id:2263|Hs108|chr10 ( 819) 3730 359.4 1.2e-98
CCDS44485.1 FGFR2 gene_id:2263|Hs108|chr10 ( 704) 3686 355.3 1.8e-97
CCDS7620.2 FGFR2 gene_id:2263|Hs108|chr10 ( 822) 3615 348.8 1.9e-95
CCDS53584.1 FGFR2 gene_id:2263|Hs108|chr10 ( 707) 3555 343.2 8e-94
CCDS44488.1 FGFR2 gene_id:2263|Hs108|chr10 ( 680) 3396 328.6 2e-89
CCDS44489.1 FGFR2 gene_id:2263|Hs108|chr10 ( 769) 3347 324.1 5e-88
CCDS3353.1 FGFR3 gene_id:2261|Hs108|chr4 ( 806) 3268 316.8 8.1e-86
CCDS81514.1 FGFR2 gene_id:2263|Hs108|chr10 ( 593) 3140 304.9 2.3e-82
CCDS54706.1 FGFR3 gene_id:2261|Hs108|chr4 ( 808) 3083 299.8 1.1e-80
CCDS4410.1 FGFR4 gene_id:2264|Hs108|chr5 ( 802) 2939 286.5 1.1e-76
CCDS44486.1 FGFR2 gene_id:2263|Hs108|chr10 ( 709) 2575 252.9 1.3e-66
CCDS44487.1 FGFR2 gene_id:2263|Hs108|chr10 ( 705) 2328 230.1 9e-60
CCDS3354.1 FGFR3 gene_id:2261|Hs108|chr4 ( 694) 2114 210.4 7.7e-54
CCDS4411.1 FGFR4 gene_id:2264|Hs108|chr5 ( 762) 1824 183.7 9.2e-46
CCDS78096.1 FGFR4 gene_id:2264|Hs108|chr5 ( 734) 1664 168.9 2.5e-41
CCDS53525.1 RET gene_id:5979|Hs108|chr10 (1072) 1120 119.0 4e-26
CCDS7200.1 RET gene_id:5979|Hs108|chr10 (1114) 1120 119.0 4.1e-26
CCDS482.1 TIE1 gene_id:7075|Hs108|chr1 (1138) 850 94.1 1.3e-18
CCDS78389.1 TEK gene_id:7010|Hs108|chr9 ( 976) 829 92.1 4.4e-18
CCDS75825.1 TEK gene_id:7010|Hs108|chr9 (1081) 829 92.1 4.7e-18
CCDS6519.1 TEK gene_id:7010|Hs108|chr9 (1124) 829 92.2 4.9e-18
CCDS58399.1 NTRK3 gene_id:4916|Hs108|chr15 ( 817) 778 87.3 1e-16
CCDS75874.1 MUSK gene_id:4593|Hs108|chr9 ( 783) 750 84.7 6e-16
CCDS48005.1 MUSK gene_id:4593|Hs108|chr9 ( 869) 750 84.7 6.4e-16
CCDS1161.1 NTRK1 gene_id:4914|Hs108|chr1 ( 796) 747 84.4 7.3e-16
CCDS3497.1 KDR gene_id:3791|Hs108|chr4 (1356) 741 84.1 1.5e-15
CCDS30890.1 NTRK1 gene_id:4914|Hs108|chr1 ( 760) 726 82.5 2.7e-15
CCDS30891.1 NTRK1 gene_id:4914|Hs108|chr1 ( 790) 726 82.5 2.8e-15
CCDS35050.1 NTRK2 gene_id:4915|Hs108|chr9 ( 822) 726 82.5 2.9e-15
CCDS10340.1 NTRK3 gene_id:4916|Hs108|chr15 ( 825) 726 82.5 2.9e-15
CCDS6671.1 NTRK2 gene_id:4915|Hs108|chr9 ( 838) 726 82.5 2.9e-15
CCDS9330.1 FLT1 gene_id:2321|Hs108|chr13 (1338) 720 82.2 5.8e-15
CCDS5116.1 ROS1 gene_id:6098|Hs108|chr6 (2347) 724 82.8 6.6e-15
CCDS73785.1 IGF1R gene_id:3480|Hs108|chr15 (1366) 710 81.3 1.1e-14
CCDS10378.1 IGF1R gene_id:3480|Hs108|chr15 (1367) 710 81.3 1.1e-14
CCDS47058.1 KIT gene_id:3815|Hs108|chr4 ( 972) 690 79.3 3.2e-14
CCDS3496.1 KIT gene_id:3815|Hs108|chr4 ( 976) 690 79.3 3.2e-14
CCDS42487.1 INSR gene_id:3643|Hs108|chr19 (1370) 689 79.3 4.3e-14
CCDS12176.1 INSR gene_id:3643|Hs108|chr19 (1382) 689 79.3 4.3e-14
CCDS62677.1 AXL gene_id:558|Hs108|chr19 ( 626) 670 77.2 8.5e-14
CCDS43412.1 FLT4 gene_id:2324|Hs108|chr5 (1298) 675 78.0 1e-13
>>CCDS43730.1 FGFR1 gene_id:2260|Hs108|chr8 (733 aa)
initn: 4987 init1: 4987 opt: 4987 Z-score: 2511.1 bits: 475.3 E(32554): 1.5e-133
Smith-Waterman score: 4987; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
670 680 690 700 710 720
730
pF1KB5 HPAQLANGGLKRR
:::::::::::::
CCDS43 HPAQLANGGLKRR
730
>>CCDS43731.1 FGFR1 gene_id:2260|Hs108|chr8 (731 aa)
initn: 4610 init1: 4610 opt: 4959 Z-score: 2497.2 bits: 472.7 E(32554): 8.9e-133
Smith-Waterman score: 4959; 99.7% identity (99.7% similar) in 733 aa overlap (1-733:1-731)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN--
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB5 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB5 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB5 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
660 670 680 690 700 710
730
pF1KB5 HPAQLANGGLKRR
:::::::::::::
CCDS43 HPAQLANGGLKRR
720 730
>>CCDS6107.2 FGFR1 gene_id:2260|Hs108|chr8 (822 aa)
initn: 4973 init1: 4765 opt: 4765 Z-score: 2399.9 bits: 454.9 E(32554): 2.3e-127
Smith-Waterman score: 4765; 100.0% identity (100.0% similar) in 703 aa overlap (31-733:120-822)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::::::::::::::::::::::::::::::
CCDS61 DSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRM
90 100 110 120 130 140
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
210 220 230 240 250 260
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
270 280 290 300 310 320
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
330 340 350 360 370 380
310 320 330 340 350 360
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
390 400 410 420 430 440
370 380 390 400 410 420
pF1KB5 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
450 460 470 480 490 500
430 440 450 460 470 480
pF1KB5 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
510 520 530 540 550 560
490 500 510 520 530 540
pF1KB5 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
570 580 590 600 610 620
550 560 570 580 590 600
pF1KB5 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
630 640 650 660 670 680
610 620 630 640 650 660
pF1KB5 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
690 700 710 720 730 740
670 680 690 700 710 720
pF1KB5 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
750 760 770 780 790 800
730
pF1KB5 HPAQLANGGLKRR
:::::::::::::
CCDS61 HPAQLANGGLKRR
810 820
>>CCDS55221.1 FGFR1 gene_id:2260|Hs108|chr8 (812 aa)
initn: 2678 init1: 2678 opt: 4741 Z-score: 2388.1 bits: 452.6 E(32554): 1.1e-126
Smith-Waterman score: 4741; 99.7% identity (99.7% similar) in 703 aa overlap (31-733:112-812)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::::::::::::::::::::::::::::::
CCDS55 DSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRM
90 100 110 120 130 140
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
210 220 230 240 250 260
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
270 280 290 300 310 320
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
330 340 350 360 370 380
310 320 330 340 350 360
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
CCDS55 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQ--VSADSSASMNSGVLLVRPSRL
390 400 410 420 430
370 380 390 400 410 420
pF1KB5 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
440 450 460 470 480 490
430 440 450 460 470 480
pF1KB5 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
500 510 520 530 540 550
490 500 510 520 530 540
pF1KB5 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
560 570 580 590 600 610
550 560 570 580 590 600
pF1KB5 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
620 630 640 650 660 670
610 620 630 640 650 660
pF1KB5 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
680 690 700 710 720 730
670 680 690 700 710 720
pF1KB5 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
740 750 760 770 780 790
730
pF1KB5 HPAQLANGGLKRR
:::::::::::::
CCDS55 HPAQLANGGLKRR
800 810
>>CCDS55222.1 FGFR1 gene_id:2260|Hs108|chr8 (820 aa)
initn: 3062 init1: 2678 opt: 4741 Z-score: 2388.0 bits: 452.6 E(32554): 1.1e-126
Smith-Waterman score: 4741; 99.7% identity (99.7% similar) in 703 aa overlap (31-733:120-820)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::::::::::::::::::::::::::::::
CCDS55 DSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRM
90 100 110 120 130 140
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
210 220 230 240 250 260
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
270 280 290 300 310 320
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
330 340 350 360 370 380
310 320 330 340 350 360
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
CCDS55 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQ--VSADSSASMNSGVLLVRPSRL
390 400 410 420 430 440
370 380 390 400 410 420
pF1KB5 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
450 460 470 480 490 500
430 440 450 460 470 480
pF1KB5 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
510 520 530 540 550 560
490 500 510 520 530 540
pF1KB5 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
570 580 590 600 610 620
550 560 570 580 590 600
pF1KB5 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
630 640 650 660 670 680
610 620 630 640 650 660
pF1KB5 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
690 700 710 720 730 740
670 680 690 700 710 720
pF1KB5 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
750 760 770 780 790 800
730
pF1KB5 HPAQLANGGLKRR
:::::::::::::
CCDS55 HPAQLANGGLKRR
810 820
>>CCDS43732.1 FGFR1 gene_id:2260|Hs108|chr8 (820 aa)
initn: 4818 init1: 4610 opt: 4737 Z-score: 2386.0 bits: 452.3 E(32554): 1.4e-126
Smith-Waterman score: 4737; 99.7% identity (99.7% similar) in 703 aa overlap (31-733:120-820)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::::::::::::::::::::::::::::
CCDS43 DSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPN--
90 100 110 120 130 140
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
210 220 230 240 250 260
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
270 280 290 300 310 320
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
330 340 350 360 370 380
310 320 330 340 350 360
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
390 400 410 420 430 440
370 380 390 400 410 420
pF1KB5 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
450 460 470 480 490 500
430 440 450 460 470 480
pF1KB5 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
510 520 530 540 550 560
490 500 510 520 530 540
pF1KB5 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
570 580 590 600 610 620
550 560 570 580 590 600
pF1KB5 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
630 640 650 660 670 680
610 620 630 640 650 660
pF1KB5 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
690 700 710 720 730 740
670 680 690 700 710 720
pF1KB5 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
750 760 770 780 790 800
730
pF1KB5 HPAQLANGGLKRR
:::::::::::::
CCDS43 HPAQLANGGLKRR
810 820
>>CCDS55223.1 FGFR1 gene_id:2260|Hs108|chr8 (853 aa)
initn: 4818 init1: 4610 opt: 4737 Z-score: 2385.8 bits: 452.3 E(32554): 1.4e-126
Smith-Waterman score: 4737; 99.7% identity (99.7% similar) in 703 aa overlap (31-733:153-853)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::::::::::::::::::::::::::::
CCDS55 DSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPN--
130 140 150 160 170 180
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
190 200 210 220 230 240
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
250 260 270 280 290 300
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
310 320 330 340 350 360
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
370 380 390 400 410 420
310 320 330 340 350 360
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
430 440 450 460 470 480
370 380 390 400 410 420
pF1KB5 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
490 500 510 520 530 540
430 440 450 460 470 480
pF1KB5 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
550 560 570 580 590 600
490 500 510 520 530 540
pF1KB5 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
610 620 630 640 650 660
550 560 570 580 590 600
pF1KB5 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
670 680 690 700 710 720
610 620 630 640 650 660
pF1KB5 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
730 740 750 760 770 780
670 680 690 700 710 720
pF1KB5 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
790 800 810 820 830 840
730
pF1KB5 HPAQLANGGLKRR
:::::::::::::
CCDS55 HPAQLANGGLKRR
850
>>CCDS73210.1 FGFR2 gene_id:2263|Hs108|chr10 (732 aa)
initn: 3749 init1: 2074 opt: 3803 Z-score: 1921.3 bits: 366.1 E(32554): 1.1e-100
Smith-Waterman score: 3803; 75.6% identity (90.8% similar) in 737 aa overlap (1-731:1-731)
10 20 30 40 50
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDAL-PS---SEDDDDDDDSSSEEKETDNTK
: :: .. .:.. ::: :::: .: :. .: : : ::.:: ...:. ..:..
CCDS73 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 PNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG
.: :::::. :::::.:::::::.::::.::..:.: ::.:::::::::: .:::::
CCDS73 NKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGG
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 YKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANK
:::: ::.::.::::::::::::.::::::::::::.::::::::::::::::::::
CCDS73 YKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEV
....:..:::.:::::: ::::::.::.: :::: :::.:::...::.:::::::::.::
CCDS73 STVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 LHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAF
:..:::.::::::::::::::::.: :::::::: : .. . .:: :::: ::: :.:
CCDS73 LYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 LISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVR
::.::: .::. .::. ::: :: :: :::::.: :::::::::::.::.::::.. :::
CCDS73 LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 -PSRLSSSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKD
.::::.. ::::::::::::::::.::.:::.:.::::::::::::::.:::.:.:::
CCDS73 ITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKD
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 KPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
::.... :::::::.::::::::::.::::::::::::::::::::::::::::::::::
CCDS73 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 ASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRD
::::::::::.::::::.:: :. .. ::::.. ::::::.::.:::::::::.::::::
CCDS73 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB5 LAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDV
::::::::::.::::::::::::::..:::::::::::::::::::::::::.:::::::
CCDS73 LAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB5 WSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQ
::::::.:::::::::::::.::::::::::::::::::.::::::::::::::::::::
CCDS73 WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQ
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB5 RPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPE
::::::::::::::..::.:.::::::.::.:::::.:::::: ::::.::::: .:.:
CCDS73 RPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS-CSSGDDSVFSPDPMPY
660 670 680 690 700 710
720 730
pF1KB5 EPCLPRHPAQLANGGLKRR
:::::..: ::..:
CCDS73 EPCLPQYPH--INGSVKT
720 730
>>CCDS31298.1 FGFR2 gene_id:2263|Hs108|chr10 (821 aa)
initn: 3806 init1: 2074 opt: 3754 Z-score: 1896.3 bits: 361.6 E(32554): 2.7e-99
Smith-Waterman score: 3754; 77.4% identity (92.5% similar) in 703 aa overlap (31-731:126-820)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::. :..:.:: : ..:. ..:.. .:
CCDS31 GATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTD--GAEDFVSENSNNKR-
100 110 120 130 140 150
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
:::::. :::::.:::::::.::::.::..:.: ::.:::::::::: .:::::::::
CCDS31 --APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVR
160 170 180 190 200 210
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::.::.::::::::::::.::::::::::::.:::::::::::::::::::: ....
CCDS31 NQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
220 230 240 250 260 270
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
:..:::.:::::: ::::::.::.: :::: :::.:::...::.:::::::::.:::..:
CCDS31 GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIR
280 290 300 310 320 330
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::.::::::::::::::::.: :::::::: : .. . .:: :::: ::: :.:::.:
CCDS31 NVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIAC
340 350 360 370 380 390
310 320 330 340 350
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVR-PSR
:: .::. .::. ::: :: :: :::::.: :::::::::::.::.::::.. ::: .:
CCDS31 MVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTR
400 410 420 430 440 450
360 370 380 390 400 410
pF1KB5 LSSSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNR
:::.. ::::::::::::::::.::.:::.:.::::::::::::::.:::.:.:::::..
CCDS31 LSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKE
460 470 480 490 500 510
420 430 440 450 460 470
pF1KB5 VTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKG
.. :::::::.::::::::::.::::::::::::::::::::::::::::::::::::::
CCDS31 AVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKG
520 530 540 550 560 570
480 490 500 510 520 530
pF1KB5 NLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAAR
::::::.::::::.:: :. .. ::::.. ::::::.::.:::::::::.::::::::::
CCDS31 NLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAAR
580 590 600 610 620 630
540 550 560 570 580 590
pF1KB5 NVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFG
::::::.::::::::::::::..:::::::::::::::::::::::::.:::::::::::
CCDS31 NVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFG
640 650 660 670 680 690
600 610 620 630 640 650
pF1KB5 VLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTF
::.:::::::::::::.::::::::::::::::::.::::::::::::::::::::::::
CCDS31 VLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTF
700 710 720 730 740 750
660 670 680 690 700 710
pF1KB5 KQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCL
::::::::::..::.:.::::::.::.:::::.:::::: ::::.::::: .:.: ::::
CCDS31 KQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS-CSSGDDSVFSPDPMPYEPCL
760 770 780 790 800
720 730
pF1KB5 PRHPAQLANGGLKRR
:..: ::..:
CCDS31 PQYPH--INGSVKT
810 820
>>CCDS81515.1 FGFR2 gene_id:2263|Hs108|chr10 (819 aa)
initn: 3867 init1: 3536 opt: 3730 Z-score: 1884.3 bits: 359.4 E(32554): 1.2e-98
Smith-Waterman score: 3730; 77.1% identity (92.2% similar) in 703 aa overlap (31-731:126-818)
10 20 30 40 50 60
pF1KB5 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
::. :..:.:: : ..:. ..:.. .:
CCDS81 GATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTD--GAEDFVSENSNNKR-
100 110 120 130 140 150
70 80 90 100 110 120
pF1KB5 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
:::::. :::::.:::::::.::::.::..:.: ::.:::::::::: .:::::::::
CCDS81 --APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVR
160 170 180 190 200 210
130 140 150 160 170 180
pF1KB5 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
::.::.::::::::::::.::::::::::::.:::::::::::::::::::: ....
CCDS81 NQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
220 230 240 250 260 270
190 200 210 220 230 240
pF1KB5 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
:..:::.:::::: ::::::.::.: :::: :::.:::...::.:::::::::.:::..:
CCDS81 GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIR
280 290 300 310 320 330
250 260 270 280 290 300
pF1KB5 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
::.::::::::::::::::.: :::::::: : .. . .:: :::: ::: :.:::.:
CCDS81 NVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIAC
340 350 360 370 380 390
310 320 330 340 350
pF1KB5 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVR-PSR
:: .::. .::. ::: :: :: :::::.: ::::::: ::.::.::::.. ::: .:
CCDS81 MVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQV--SAESSSSMNSNTPLVRITTR
400 410 420 430 440
360 370 380 390 400 410
pF1KB5 LSSSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNR
:::.. ::::::::::::::::.::.:::.:.::::::::::::::.:::.:.:::::..
CCDS81 LSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKE
450 460 470 480 490 500
420 430 440 450 460 470
pF1KB5 VTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKG
.. :::::::.::::::::::.::::::::::::::::::::::::::::::::::::::
CCDS81 AVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKG
510 520 530 540 550 560
480 490 500 510 520 530
pF1KB5 NLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAAR
::::::.::::::.:: :. .. ::::.. ::::::.::.:::::::::.::::::::::
CCDS81 NLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAAR
570 580 590 600 610 620
540 550 560 570 580 590
pF1KB5 NVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFG
::::::.::::::::::::::..:::::::::::::::::::::::::.:::::::::::
CCDS81 NVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFG
630 640 650 660 670 680
600 610 620 630 640 650
pF1KB5 VLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTF
::.:::::::::::::.::::::::::::::::::.::::::::::::::::::::::::
CCDS81 VLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTF
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB5 KQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCL
::::::::::..::.:.::::::.::.:::::.:::::: ::::.::::: .:.: ::::
CCDS81 KQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS-CSSGDDSVFSPDPMPYEPCL
750 760 770 780 790 800
720 730
pF1KB5 PRHPAQLANGGLKRR
:..: ::..:
CCDS81 PQYPH--INGSVKT
810
733 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:37:16 2016 done: Sat Nov 5 20:37:17 2016
Total Scan time: 4.150 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]