Result of FASTA (omim) for
pFN21AB9771
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9771, 538 aa
1>>>pF1KB9771 538 - 538 aa - 538 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4102+/-0.000429; mu= 4.8252+/- 0.027
mean_var=222.1072+/-46.831, 0's: 0 Z-trim(118.3): 117 B-trim: 1504 in 1/54
Lambda= 0.086058
statistics sampled from 31028 (31193) to 31028 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.366), width: 16
Scan time: 11.330
The best scores are: opt bits E(85289)
NP_005048 (OMIM: 600697) retinoblastoma-binding pr ( 538) 3620 462.7 1.3e-129
XP_011508135 (OMIM: 600697) PREDICTED: retinoblast ( 537) 3603 460.6 5.5e-129
NP_001180201 (OMIM: 600697) retinoblastoma-binding ( 500) 3315 424.8 3e-118
NP_001180202 (OMIM: 600697) retinoblastoma-binding ( 410) 2699 348.3 2.8e-95
>>NP_005048 (OMIM: 600697) retinoblastoma-binding protei (538 aa)
initn: 3620 init1: 3620 opt: 3620 Z-score: 2448.1 bits: 462.7 E(85289): 1.3e-129
Smith-Waterman score: 3620; 99.8% identity (99.8% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KB9 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NKVLVCPMKSAPVMLTLSDSKHVFLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_005 NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
490 500 510 520 530
>>XP_011508135 (OMIM: 600697) PREDICTED: retinoblastoma- (537 aa)
initn: 3600 init1: 3576 opt: 3603 Z-score: 2436.7 bits: 460.6 E(85289): 5.5e-129
Smith-Waterman score: 3603; 99.6% identity (99.6% similar) in 538 aa overlap (1-538:1-537)
10 20 30 40 50 60
pF1KB9 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NKVLVCPMKSAPVMLTLSDSKHVFLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_011 NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLT-GGAISELL
490 500 510 520 530
>>NP_001180201 (OMIM: 600697) retinoblastoma-binding pro (500 aa)
initn: 3315 init1: 3315 opt: 3315 Z-score: 2243.9 bits: 424.8 E(85289): 3e-118
Smith-Waterman score: 3315; 99.8% identity (99.8% similar) in 491 aa overlap (1-491:1-491)
10 20 30 40 50 60
pF1KB9 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NKVLVCPMKSAPVMLTLSDSKHVFLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
:::::::::::
NP_001 KKQAGRPKGSKAGGAISELL
490 500
>>NP_001180202 (OMIM: 600697) retinoblastoma-binding pro (410 aa)
initn: 2696 init1: 2672 opt: 2699 Z-score: 1831.7 bits: 348.3 E(85289): 2.8e-95
Smith-Waterman score: 2699; 99.5% identity (99.5% similar) in 411 aa overlap (128-538:1-410)
100 110 120 130 140 150
pF1KB9 GDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVFLPVDDDSDLNVVA
:::::::::::::::: :::::::::::::
NP_001 MKSAPVMLTLSDSKHVVLPVDDDSDLNVVA
10 20 30
160 170 180 190 200 210
pF1KB9 SFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINT
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB9 ADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALY
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB9 IWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFK
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB9 ELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSK
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB9 ALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNI
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB9 ELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAK
340 350 360 370 380 390
520 530
pF1KB9 GKVQAELSQPLTAGGAISELL
:::::::::::: ::::::::
NP_001 GKVQAELSQPLT-GGAISELL
400 410
538 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:27:07 2016 done: Fri Nov 4 21:27:09 2016
Total Scan time: 11.330 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]