Result of FASTA (ccds) for
pFN21AE0668
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0668, 393 aa
1>>>pF1KE0668 393 - 393 aa - 393 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7708+/-0.000947; mu= 5.9719+/- 0.056
mean_var=234.2741+/-51.670, 0's: 0 Z-trim(112.4): 631 B-trim: 0 in 0/51
Lambda= 0.083794
statistics sampled from 12415 (13174) to 12415 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.405), width: 16
Scan time: 3.080
The best scores are: opt bits E(32554)
CCDS10216.1 MAP2K1 gene_id:5604|Hs108|chr15 ( 393) 2625 330.4 1.8e-90
CCDS12120.1 MAP2K2 gene_id:5605|Hs108|chr19 ( 400) 2130 270.5 1.9e-72
CCDS55970.1 MAP2K5 gene_id:5607|Hs108|chr15 ( 412) 808 110.7 2.4e-24
CCDS10224.1 MAP2K5 gene_id:5607|Hs108|chr15 ( 448) 808 110.8 2.6e-24
CCDS42051.1 MAP2K5 gene_id:5607|Hs108|chr15 ( 438) 761 105.1 1.3e-22
CCDS11686.1 MAP2K6 gene_id:5608|Hs108|chr17 ( 334) 636 89.8 3.8e-18
CCDS11162.1 MAP2K4 gene_id:6416|Hs108|chr17 ( 399) 612 87.0 3.2e-17
CCDS62095.1 MAP2K4 gene_id:6416|Hs108|chr17 ( 410) 612 87.0 3.3e-17
CCDS11218.1 MAP2K3 gene_id:5606|Hs108|chr17 ( 318) 608 86.4 3.9e-17
CCDS11217.1 MAP2K3 gene_id:5606|Hs108|chr17 ( 347) 608 86.5 4.1e-17
CCDS82194.1 MAP2K6 gene_id:5608|Hs108|chr17 ( 278) 600 85.4 7e-17
CCDS42491.1 MAP2K7 gene_id:5609|Hs108|chr19 ( 419) 590 84.4 2.1e-16
CCDS74277.1 MAP2K7 gene_id:5609|Hs108|chr19 ( 435) 590 84.4 2.2e-16
CCDS74278.1 MAP2K7 gene_id:5609|Hs108|chr19 ( 426) 556 80.3 3.7e-15
CCDS13341.1 STK4 gene_id:6789|Hs108|chr20 ( 487) 510 74.8 1.9e-13
CCDS59108.1 STK3 gene_id:6788|Hs108|chr8 ( 519) 510 74.8 2e-13
CCDS47900.1 STK3 gene_id:6788|Hs108|chr8 ( 491) 509 74.7 2.1e-13
CCDS2549.1 STK25 gene_id:10494|Hs108|chr2 ( 426) 483 71.5 1.7e-12
CCDS32001.1 STK24 gene_id:8428|Hs108|chr13 ( 431) 478 70.9 2.6e-12
CCDS9488.1 STK24 gene_id:8428|Hs108|chr13 ( 443) 478 70.9 2.6e-12
CCDS14631.1 STK26 gene_id:51765|Hs108|chrX ( 416) 469 69.8 5.3e-12
CCDS34290.1 STK10 gene_id:6793|Hs108|chr5 ( 968) 449 67.8 4.9e-11
CCDS42564.1 MAP4K1 gene_id:11184|Hs108|chr19 ( 821) 446 67.3 5.7e-11
CCDS59385.1 MAP4K1 gene_id:11184|Hs108|chr19 ( 833) 446 67.3 5.7e-11
>>CCDS10216.1 MAP2K1 gene_id:5604|Hs108|chr15 (393 aa)
initn: 2625 init1: 2625 opt: 2625 Z-score: 1737.8 bits: 330.4 E(32554): 1.8e-90
Smith-Waterman score: 2625; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KE0 MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
310 320 330 340 350 360
370 380 390
pF1KE0 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
:::::::::::::::::::::::::::::::::
CCDS10 IKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
370 380 390
>>CCDS12120.1 MAP2K2 gene_id:5605|Hs108|chr19 (400 aa)
initn: 2120 init1: 1539 opt: 2130 Z-score: 1414.3 bits: 270.5 E(32554): 1.9e-72
Smith-Waterman score: 2130; 80.4% identity (92.0% similar) in 398 aa overlap (1-391:2-399)
10 20 30 40 50
pF1KE0 MPKKKPT-P-IQLNPA-PDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQ
. ..::. : . .::. .: . .. ...:.:: ::::::::::::::.:::::::::
CCDS12 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 KQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQ
: :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::
CCDS12 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKG
::::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..:
CCDS12 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 LTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
:.::::::.:::::::::::::::::::::::::::::::::::::::::::::.:::::
CCDS12 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQV----EGDAAETPPRPRT
:::::::::::::::::::.:::::::::::::::: .:: : ::. ::::
CCDS12 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 PGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADL
::::.:..:::::: :::::::::::::::::::.:::. .::.::::::::::::::::
CCDS12 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
310 320 330 340 350 360
360 370 380 390
pF1KE0 KQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
:.: :.:::::..::::::::::.:. ::::.:::..:
CCDS12 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
370 380 390 400
>>CCDS55970.1 MAP2K5 gene_id:5607|Hs108|chr15 (412 aa)
initn: 917 init1: 400 opt: 808 Z-score: 550.5 bits: 110.7 E(32554): 2.4e-24
Smith-Waterman score: 885; 42.6% identity (69.7% similar) in 333 aa overlap (48-379:110-402)
20 30 40 50 60 70
pF1KE0 SAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAG
:. : : . :.....:.. . :: :
CCDS55 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
80 90 100 110 120 130
80 90 100 110 120 130
pF1KE0 NGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
:::.:.:. : ::: ..: :.: :.: ...::. ::..:..:.: ::.::::::. ..
CCDS55 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE0 EISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNIL
.:::: : ::::::: : .: .::..::....::.:::::: . ::.::::::::.:
CCDS55 RISICTEFMDGGSLD-VYRK---MPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
200 210 220 230 240 250
200 210 220 230 240 250
pF1KE0 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA
::.::..:::::::: ::..:.:...::: .::.:::..: .:...::.::.:.:..:.:
CCDS55 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA
260 270 280 290 300 310
260 270 280 290 300 310
pF1KE0 VGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYI
.::.: : . .. :: :: .::. :
CCDS55 LGRFPYPQIQKNQGSLM---------------------PL--------------QLLQCI
320 330
320 330 340 350 360 370
pF1KE0 VNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-KRSDAEEVDFAGWLC
:.: : :: : :: : :...:. :.: :: ..:: : :: . .:.. . . :.:
CCDS55 VDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVC
340 350 360 370 380 390
380 390
pF1KE0 STIGLNQPSTPTHAAGV
..
CCDS55 RALEERRSQQGPP
400 410
>>CCDS10224.1 MAP2K5 gene_id:5607|Hs108|chr15 (448 aa)
initn: 917 init1: 400 opt: 808 Z-score: 550.1 bits: 110.8 E(32554): 2.6e-24
Smith-Waterman score: 885; 42.6% identity (69.7% similar) in 333 aa overlap (48-379:146-438)
20 30 40 50 60 70
pF1KE0 SAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAG
:. : : . :.....:.. . :: :
CCDS10 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
120 130 140 150 160 170
80 90 100 110 120 130
pF1KE0 NGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
:::.:.:. : ::: ..: :.: :.: ...::. ::..:..:.: ::.::::::. ..
CCDS10 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
180 190 200 210 220 230
140 150 160 170 180 190
pF1KE0 EISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNIL
.:::: : ::::::: : .: .::..::....::.:::::: . ::.::::::::.:
CCDS10 RISICTEFMDGGSLD-VYRK---MPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
240 250 260 270 280 290
200 210 220 230 240 250
pF1KE0 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA
::.::..:::::::: ::..:.:...::: .::.:::..: .:...::.::.:.:..:.:
CCDS10 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA
300 310 320 330 340 350
260 270 280 290 300 310
pF1KE0 VGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYI
.::.: : . .. :: :: .::. :
CCDS10 LGRFPYPQIQKNQGSLM---------------------PL--------------QLLQCI
360 370
320 330 340 350 360 370
pF1KE0 VNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-KRSDAEEVDFAGWLC
:.: : :: : :: : :...:. :.: :: ..:: : :: . .:.. . . :.:
CCDS10 VDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVC
380 390 400 410 420 430
380 390
pF1KE0 STIGLNQPSTPTHAAGV
..
CCDS10 RALEERRSQQGPP
440
>>CCDS42051.1 MAP2K5 gene_id:5607|Hs108|chr15 (438 aa)
initn: 868 init1: 351 opt: 761 Z-score: 519.5 bits: 105.1 E(32554): 1.3e-22
Smith-Waterman score: 814; 41.1% identity (67.6% similar) in 333 aa overlap (48-379:146-428)
20 30 40 50 60 70
pF1KE0 SAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAG
:. : : . :.....:.. . :: :
CCDS42 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
120 130 140 150 160 170
80 90 100 110 120 130
pF1KE0 NGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
:::.:.:. : ::: ..: :.: :.: ...::. ::..:..:.: ::.::::::. ..
CCDS42 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
180 190 200 210 220 230
140 150 160 170 180 190
pF1KE0 EISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNIL
.:::: : ::::::: : .: .::..::....::.:::::: . ::.::::::::.:
CCDS42 RISICTEFMDGGSLD-VYRK---MPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
240 250 260 270 280 290
200 210 220 230 240 250
pF1KE0 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA
::.::..:::::::: ::..:.:...::: .::.:::..: .:...::.::.:.:..:.
CCDS42 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMEI-
300 310 320 330 340
260 270 280 290 300 310
pF1KE0 VGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYI
. .. :: :: .::. :
CCDS42 ---------QKNQGSLM---------------------PL--------------QLLQCI
350 360
320 330 340 350 360 370
pF1KE0 VNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-KRSDAEEVDFAGWLC
:.: : :: : :: : :...:. :.: :: ..:: : :: . .:.. . . :.:
CCDS42 VDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVC
370 380 390 400 410 420
380 390
pF1KE0 STIGLNQPSTPTHAAGV
..
CCDS42 RALEERRSQQGPP
430
>>CCDS11686.1 MAP2K6 gene_id:5608|Hs108|chr17 (334 aa)
initn: 767 init1: 286 opt: 636 Z-score: 439.2 bits: 89.8 E(32554): 3.8e-18
Smith-Waterman score: 727; 38.0% identity (63.2% similar) in 329 aa overlap (62-380:47-333)
40 50 60 70 80 90
pF1KE0 ALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSG
:.: ::.: : ::: : ::: :. : :::
CCDS11 KEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSG
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE0 LVMARKLIHLEIKPAIRNQIIRELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS
.:: : :. .. ..... .:.. .. . :. : ::::.. .:.. :::: :: :
CCDS11 QIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDT-S
80 90 100 110 120 130
160 170 180 190 200
pF1KE0 LD----QVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKL
:: ::. :. :::.::::......:.: .:. : ...::::::::.:.:. :..:.
CCDS11 LDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKM
140 150 160 170 180 190
210 220 230 240 250 260
pF1KE0 CDFGVSGQLIDSMANSF-VGTRSYMSPER----LQGTHYSVQSDIWSMGLSLVEMAVGRY
::::.:: :.::.:... .: . ::.::: :. :::.:::::.:....:.:. :.
CCDS11 CDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRF
200 210 220 230 240 250
270 280 290 300 310 320
pF1KE0 PIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEP
: :. :: :. : .:.::
CCDS11 PY------------------DSWGTP-----------------------FQQLKQVVEEP
260 270
330 340 350 360 370 380
pF1KE0 PPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGL
:.::. :: :: ::...:: :: :: .:: : :. ... .: :... .:
CCDS11 SPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
280 290 300 310 320 330
390
pF1KE0 NQPSTPTHAAGV
>>CCDS11162.1 MAP2K4 gene_id:6416|Hs108|chr17 (399 aa)
initn: 641 init1: 285 opt: 612 Z-score: 422.6 bits: 87.0 E(32554): 3.2e-17
Smith-Waterman score: 676; 36.2% identity (62.3% similar) in 337 aa overlap (66-388:100-393)
40 50 60 70 80 90
pF1KE0 KLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMA
.:.. ..:.: : : : :. ::::: .::
CCDS11 NPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 RKLIHLEIKPAIRNQIIRELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQV
: :. . ..:.. .:.: .. . :::: ::::.. .:. :::: :. :.:.
CCDS11 VKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMST-SFDKF
130 140 150 160 170 180
160 170 180 190 200
pF1KE0 LKKAGR-----IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDF
: . :::.::::...:..:.:..:.:. ::.:::.::::::.. :.::::::
CCDS11 YKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDF
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE0 GVSGQLIDSMANSF-VGTRSYMSPERLQGTH----YSVQSDIWSMGLSLVEMAVGRYPIP
:.::::.::.:.. .: : ::.:::.. . :.:.::.::.:..: :.:.::.: :
CCDS11 GISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE0 PPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPK
.. .:. : .:. ::.
CCDS11 KWNS-----------------------------------------VFDQLTQVVKGDPPQ
310 320
330 340 350 360 370 380
pF1KE0 LPSGV---FSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGL
: .. :: : .::: :: :. ..: :.:. : :: . . :. : ..:. .
CCDS11 LSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILD-
330 340 350 360 370 380
390
pF1KE0 NQPSTPTHAAGV
..:.::.
CCDS11 QMPATPSSPMYVD
390
>>CCDS62095.1 MAP2K4 gene_id:6416|Hs108|chr17 (410 aa)
initn: 664 init1: 285 opt: 612 Z-score: 422.5 bits: 87.0 E(32554): 3.3e-17
Smith-Waterman score: 676; 36.2% identity (62.3% similar) in 337 aa overlap (66-388:111-404)
40 50 60 70 80 90
pF1KE0 KLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMA
.:.. ..:.: : : : :. ::::: .::
CCDS62 NPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMA
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE0 RKLIHLEIKPAIRNQIIRELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQV
: :. . ..:.. .:.: .. . :::: ::::.. .:. :::: :. :.:.
CCDS62 VKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMST-SFDKF
150 160 170 180 190
160 170 180 190 200
pF1KE0 LKKAGR-----IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDF
: . :::.::::...:..:.:..:.:. ::.:::.::::::.. :.::::::
CCDS62 YKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDF
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE0 GVSGQLIDSMANSF-VGTRSYMSPERLQGTH----YSVQSDIWSMGLSLVEMAVGRYPIP
:.::::.::.:.. .: : ::.:::.. . :.:.::.::.:..: :.:.::.: :
CCDS62 GISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYP
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE0 PPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPK
.. .:. : .:. ::.
CCDS62 KWNS-----------------------------------------VFDQLTQVVKGDPPQ
320 330
330 340 350 360 370 380
pF1KE0 LPSGV---FSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGL
: .. :: : .::: :: :. ..: :.:. : :: . . :. : ..:. .
CCDS62 LSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILD-
340 350 360 370 380 390
390
pF1KE0 NQPSTPTHAAGV
..:.::.
CCDS62 QMPATPSSPMYVD
400 410
>>CCDS11218.1 MAP2K3 gene_id:5606|Hs108|chr17 (318 aa)
initn: 728 init1: 272 opt: 608 Z-score: 421.1 bits: 86.4 E(32554): 3.9e-17
Smith-Waterman score: 710; 36.7% identity (63.3% similar) in 338 aa overlap (53-380:20-315)
30 40 50 60 70 80
pF1KE0 TSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVV
:.: .. :.. ::. ::::: : :::
CCDS11 MSKPPAPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVV
10 20 30 40
90 100 110 120 130 140
pF1KE0 FKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQV-LHECNSPYIVGFYGAFYSDGEISI
:: : :: .:: : :. .. ..... .:.. .. . : : ::::.. .:.. :
CCDS11 EKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWI
50 60 70 80 90 100
150 160 170 180 190
pF1KE0 CMEHMDGGSLDQ----VLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNIL
::: :: :::. :: : :::.:::.........: .:. : ...::::::::.:
CCDS11 CMELMDT-SLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE0 VNSRGEIKLCDFGVSGQLIDSMANSF-VGTRSYMSPER----LQGTHYSVQSDIWSMGLS
.:..:..:.::::.:: :.::.:... .: . ::.::: :. :.:.::.::.:..
CCDS11 INKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGIT
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE0 LVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFE
..:::. :.: .. : : :.
CCDS11 MIEMAILRFPY---------------------------ESWGTP--------------FQ
230 240
320 330 340 350 360 370
pF1KE0 LLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFA
: .:.:: :.::. :: :: ::. .:: :::::: . .:: : :. ....:.:
CCDS11 QLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIA
250 260 270 280 290 300
380 390
pF1KE0 GWLCSTIGLNQPSTPTHAAGV
... .:
CCDS11 AFVKEILGEDS
310
>>CCDS11217.1 MAP2K3 gene_id:5606|Hs108|chr17 (347 aa)
initn: 728 init1: 272 opt: 608 Z-score: 420.7 bits: 86.5 E(32554): 4.1e-17
Smith-Waterman score: 710; 36.7% identity (63.3% similar) in 338 aa overlap (53-380:49-344)
30 40 50 60 70 80
pF1KE0 TSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVV
:.: .. :.. ::. ::::: : :::
CCDS11 SKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELGRGAYGVV
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE0 FKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQV-LHECNSPYIVGFYGAFYSDGEISI
:: : :: .:: : :. .. ..... .:.. .. . : : ::::.. .:.. :
CCDS11 EKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWI
80 90 100 110 120 130
150 160 170 180 190
pF1KE0 CMEHMDGGSLDQ----VLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNIL
::: :: :::. :: : :::.:::.........: .:. : ...::::::::.:
CCDS11 CMELMDT-SLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVL
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 VNSRGEIKLCDFGVSGQLIDSMANSF-VGTRSYMSPER----LQGTHYSVQSDIWSMGLS
.:..:..:.::::.:: :.::.:... .: . ::.::: :. :.:.::.::.:..
CCDS11 INKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGIT
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 LVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFE
..:::. :.: .. : : :.
CCDS11 MIEMAILRFPY---------------------------ESWGTP--------------FQ
260 270
320 330 340 350 360 370
pF1KE0 LLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFA
: .:.:: :.::. :: :: ::. .:: :::::: . .:: : :. ....:.:
CCDS11 QLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIA
280 290 300 310 320 330
380 390
pF1KE0 GWLCSTIGLNQPSTPTHAAGV
... .:
CCDS11 AFVKEILGEDS
340
393 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:11:25 2016 done: Wed Nov 2 18:11:26 2016
Total Scan time: 3.080 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]