FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1554, 273 aa 1>>>pF1KE1554 273 - 273 aa - 273 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0837+/-0.000893; mu= 7.2293+/- 0.053 mean_var=121.0320+/-24.310, 0's: 0 Z-trim(110.3): 93 B-trim: 451 in 1/52 Lambda= 0.116580 statistics sampled from 11407 (11500) to 11407 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.353), width: 16 Scan time: 2.410 The best scores are: opt bits E(32554) CCDS8618.1 OLR1 gene_id:4973|Hs108|chr12 ( 273) 1852 322.1 2.6e-88 CCDS53746.1 OLR1 gene_id:4973|Hs108|chr12 ( 189) 1249 220.6 6.6e-58 CCDS53745.1 OLR1 gene_id:4973|Hs108|chr12 ( 181) 907 163.1 1.3e-40 CCDS44830.1 CLEC12B gene_id:387837|Hs108|chr12 ( 276) 450 86.3 2.6e-17 CCDS8614.1 CLEC7A gene_id:64581|Hs108|chr12 ( 168) 412 79.8 1.4e-15 CCDS41753.1 CLEC7A gene_id:64581|Hs108|chr12 ( 247) 411 79.7 2.2e-15 CCDS8613.1 CLEC7A gene_id:64581|Hs108|chr12 ( 201) 404 78.5 4.2e-15 CCDS76528.1 CLEC1A gene_id:51267|Hs108|chr12 ( 188) 364 71.7 4.2e-13 CCDS8610.1 CLEC12B gene_id:387837|Hs108|chr12 ( 232) 361 71.3 7.1e-13 CCDS73443.1 CLEC1A gene_id:51267|Hs108|chr12 ( 247) 361 71.3 7.5e-13 CCDS8612.1 CLEC1A gene_id:51267|Hs108|chr12 ( 280) 358 70.8 1.2e-12 CCDS59344.1 CD209 gene_id:30835|Hs108|chr19 ( 268) 332 66.5 2.4e-11 CCDS45949.1 CD209 gene_id:30835|Hs108|chr19 ( 360) 334 66.9 2.4e-11 CCDS45950.1 CD209 gene_id:30835|Hs108|chr19 ( 380) 334 66.9 2.5e-11 CCDS12186.1 CD209 gene_id:30835|Hs108|chr19 ( 404) 334 66.9 2.6e-11 CCDS45952.1 CD209 gene_id:30835|Hs108|chr19 ( 312) 332 66.5 2.7e-11 CCDS59347.1 CLEC4M gene_id:10332|Hs108|chr19 ( 263) 326 65.4 4.7e-11 CCDS8611.1 CLEC9A gene_id:283420|Hs108|chr12 ( 241) 321 64.6 7.8e-11 >>CCDS8618.1 OLR1 gene_id:4973|Hs108|chr12 (273 aa) initn: 1852 init1: 1852 opt: 1852 Z-score: 1698.8 bits: 322.1 E(32554): 2.6e-88 Smith-Waterman score: 1852; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273) 10 20 30 40 50 60 pF1KE1 MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 SQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 SQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 MELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 MELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 KINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 KINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPS 190 200 210 220 230 240 250 260 270 pF1KE1 GTCAYIQRGAVYAENCILAAFSICQKKANLRAQ ::::::::::::::::::::::::::::::::: CCDS86 GTCAYIQRGAVYAENCILAAFSICQKKANLRAQ 250 260 270 >>CCDS53746.1 OLR1 gene_id:4973|Hs108|chr12 (189 aa) initn: 1249 init1: 1249 opt: 1249 Z-score: 1153.1 bits: 220.6 E(32554): 6.6e-58 Smith-Waterman score: 1249; 100.0% identity (100.0% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KE1 MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 SQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 MELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 KINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPS :::::::: CCDS53 KINSTADLI >>CCDS53745.1 OLR1 gene_id:4973|Hs108|chr12 (181 aa) initn: 904 init1: 904 opt: 907 Z-score: 842.5 bits: 163.1 E(32554): 1.3e-40 Smith-Waterman score: 907; 97.9% identity (98.6% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KE1 MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 SQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 MELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLL :::::::::::::::::::::. : CCDS53 MELHHQNLNLQETLKRVANCSGLHPASNFLFQFSILDGAVSEEPQLPMALGGRFSFDAPL 130 140 150 160 170 180 >>CCDS44830.1 CLEC12B gene_id:387837|Hs108|chr12 (276 aa) initn: 409 init1: 123 opt: 450 Z-score: 424.4 bits: 86.3 E(32554): 2.6e-17 Smith-Waterman score: 451; 31.5% identity (61.2% similar) in 276 aa overlap (1-268:10-267) 10 20 30 40 50 pF1KE1 MTFDDLK-IQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLV .::.: .. .: . .. :. : :: : :: : .::: :. CCDS44 MSEEVTYATLTFQDSAGARNNRDGNNLRKRGHPAP------SPIWRHAALGLVTLCLMLL 10 20 30 40 50 60 70 80 90 100 pF1KE1 VTIMVLGMQLSQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQE--SENELKEMIET . ...:::.. :.:. ..... .:.. .: .. :: .. ::. . :.:. : CCDS44 IGLVTLGMMFLQISNDINSDSEKLSQLQKTIQ------QQQDNLSQQLGNSNNLSMEEEF 60 70 80 90 100 110 120 130 140 150 160 pF1KE1 LARKLNE--KSKEQMELHH-QNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFN- : ... : .::: .. :.: .. . .: :. :::. : :. ..:: :... . CCDS44 LKSQISSVLKRQEQMAIKLCQELIIHTSDHR---CN-PCPKMWQWYQNSCYYFTTNEEKT 110 120 130 140 150 160 170 180 190 200 210 220 pF1KE1 WEKSQEKCLSLDAKLLKINSTADLDFIQ-QAISYSSFPFWMGLSRRNPSYPWLWEDGSPL : .:.. :.. .. :.::.: . ::.. : . . :: ::.::: . . :.::::: CCDS44 WANSRKDCIDKNSTLVKIDSLEEKDFLMSQPLLMFSF-FWLGLSWDSSGRSWFWEDGSVP 170 180 190 200 210 220 230 240 250 260 270 pF1KE1 MPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ : :: .. ..: : :::.:.: .: : : ::.: : CCDS44 SPSLFSTK-ELDQINGSKGCAYFQKGNIYISRCSAEIFWICEKTAAPVKTEDLD 230 240 250 260 270 >>CCDS8614.1 CLEC7A gene_id:64581|Hs108|chr12 (168 aa) initn: 416 init1: 235 opt: 412 Z-score: 393.0 bits: 79.8 E(32554): 1.4e-15 Smith-Waterman score: 412; 36.5% identity (71.1% similar) in 159 aa overlap (113-270:10-168) 90 100 110 120 130 140 pF1KE1 GQISARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCSA :.: . :... :. . .... . :. CCDS86 MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGVLSS 10 20 30 150 160 170 180 190 200 pF1KE1 PCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFI-QQAISYSSFP ::: .:: . ..::::: . .:. :...: .: ..::::.:. .: :: .:. : . CCDS86 PCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNS 40 50 60 70 80 90 210 220 230 240 250 260 pF1KE1 FWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAF ::.:::: . :::::::: . .::..: ...: :: .:..:. ...: . : . .. CCDS86 FWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSY 100 110 120 130 140 150 270 pF1KE1 SICQKKANLRAQ :::.:: .. CCDS86 SICEKKFSM 160 >>CCDS41753.1 CLEC7A gene_id:64581|Hs108|chr12 (247 aa) initn: 476 init1: 235 opt: 411 Z-score: 389.7 bits: 79.7 E(32554): 2.2e-15 Smith-Waterman score: 440; 31.9% identity (59.2% similar) in 260 aa overlap (16-270:21-247) 10 20 30 40 50 pF1KE1 MTFDDLKIQTVKDQPDEKSNGKKA----KGLQFLYSPWWCLAAATLGVLCLGLVV : .:: . : :: . :: : : :. ::.::: ..: CCDS41 MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKG-SCAASPPWRLIAVILGILCLVILV 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 TIMVLGMQLSQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLAR .::: . :. .. : : . .:.. :. :: ... :.. . CCDS41 IAVVLGTMAIWRSNSGSNTLEN---------GYFLSRNK-ENHSQPTQSSLEDSVTPT-- 60 70 80 90 100 120 130 140 150 160 170 pF1KE1 KLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEK ...: .. :.::: .:: . ..::::: . .:. :... CCDS41 --------------------KAVKTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQ 110 120 130 140 180 190 200 210 220 230 pF1KE1 CLSLDAKLLKINSTADLDFI-QQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRV : .: ..::::.:. .: :: .:. : . ::.:::: . :::::::: . .::.. CCDS41 CWQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQI 150 160 170 180 190 200 240 250 260 270 pF1KE1 RGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ : ...: :: .:..:. ...: . : . ..:::.:: .. CCDS41 RTTATQENPSPNCVWIHVSVIYDQLCSVPSYSICEKKFSM 210 220 230 240 >>CCDS8613.1 CLEC7A gene_id:64581|Hs108|chr12 (201 aa) initn: 476 init1: 235 opt: 404 Z-score: 384.6 bits: 78.5 E(32554): 4.2e-15 Smith-Waterman score: 404; 41.2% identity (74.0% similar) in 131 aa overlap (141-270:71-201) 120 130 140 150 160 170 pF1KE1 RKLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQE :.::: .:: . ..::::: . .:. :.. CCDS86 PPWRLIAVILGILCLVILVIAVVLGTMGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKR 50 60 70 80 90 100 180 190 200 210 220 pF1KE1 KCLSLDAKLLKINSTADLDFI-QQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFR .: .: ..::::.:. .: :: .:. : . ::.:::: . :::::::: . .::. CCDS86 QCWQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQ 110 120 130 140 150 160 230 240 250 260 270 pF1KE1 VRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ .: ...: :: .:..:. ...: . : . ..:::.:: .. CCDS86 IRTTATQENPSPNCVWIHVSVIYDQLCSVPSYSICEKKFSM 170 180 190 200 >>CCDS76528.1 CLEC1A gene_id:51267|Hs108|chr12 (188 aa) initn: 263 init1: 188 opt: 364 Z-score: 348.7 bits: 71.7 E(32554): 4.2e-13 Smith-Waterman score: 364; 33.7% identity (60.7% similar) in 163 aa overlap (113-270:12-171) 90 100 110 120 130 140 pF1KE1 GQISARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQN--LNLQETLKRVANC :.. . : :: :. . . .:.:. CCDS76 MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTAHR 10 20 30 40 150 160 170 180 190 200 pF1KE1 SAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSF .:: ..: :::.::: : . : .:: . ::: .. .::::. ::.: . ::: : CCDS76 CSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQ-SYSEF 50 60 70 80 90 100 210 220 230 240 250 pF1KE1 --PFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYP-SGTCAYIQRGAVYAENCI .: :: : . . ::: ::.:. .::.. .. : : : :. : : .....: CCDS76 FYSYWTGLLRPDSGKAWLWMDGTPFTSELFHI--IIDVTSPRSRDCVAILNGMIFSKDCK 110 120 130 140 150 260 270 pF1KE1 LAAFSICQKKANLRAQ .:...:.. CCDS76 ELKRCVCERRAGMVKPESLHVPPETLGEGD 160 170 180 >>CCDS8610.1 CLEC12B gene_id:387837|Hs108|chr12 (232 aa) initn: 404 init1: 148 opt: 361 Z-score: 344.6 bits: 71.3 E(32554): 7.1e-13 Smith-Waterman score: 362; 30.5% identity (62.3% similar) in 236 aa overlap (1-228:10-228) 10 20 30 40 50 pF1KE1 MTFDDLK-IQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLV .::.: .. .: . .. :. : :: : :: : .::: :. CCDS86 MSEEVTYATLTFQDSAGARNNRDGNNLRKRGHPAP------SPIWRHAALGLVTLCLMLL 10 20 30 40 50 60 70 80 90 100 pF1KE1 VTIMVLGMQLSQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQE--SENELKEMIET . ...:::.. :.:. ..... .:.. .: .. :: .. ::. . :.:. : CCDS86 IGLVTLGMMFLQISNDINSDSEKLSQLQKTIQ------QQQDNLSQQLGNSNNLSMEEEF 60 70 80 90 100 110 120 130 140 150 160 pF1KE1 LARKLNE--KSKEQMELHH-QNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFN- : ... : .::: .. :.: .. . .: :. :::. : :. ..:: :... . CCDS86 LKSQISSVLKRQEQMAIKLCQELIIHTSDHR---CN-PCPKMWQWYQNSCYYFTTNEEKT 110 120 130 140 150 160 170 180 190 200 210 220 pF1KE1 WEKSQEKCLSLDAKLLKINSTADLDFIQ-QAISYSSFPFWMGLSRRNPSYPWLWEDGSPL : .:.. :.. .. :.::.: . ::.. : . . :: ::.::: . . :.::::: CCDS86 WANSRKDCIDKNSTLVKIDSLEEKDFLMSQPLLMFSF-FWLGLSWDSSGRSWFWEDGSVP 170 180 190 200 210 220 230 240 250 260 270 pF1KE1 MPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ : :. CCDS86 SPSLYVSNY 230 >>CCDS73443.1 CLEC1A gene_id:51267|Hs108|chr12 (247 aa) initn: 263 init1: 188 opt: 361 Z-score: 344.2 bits: 71.3 E(32554): 7.5e-13 Smith-Waterman score: 377; 30.2% identity (56.9% similar) in 232 aa overlap (59-270:4-230) 30 40 50 60 70 80 pF1KE1 FLYSPWWCLAAATLGVLCLGLVVTIMVLGMQLSQVSDLLTQE---QANLTHQKKKLEGQI . :.. :.: .. .: : . . CCDS73 MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHP 10 20 30 90 100 110 120 130 pF1KE1 SARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVAN------ :. . . : : : .. : . ..:.. :.: . :. ::..: .:..::. CCDS73 EPRRTVFQYYQLS-NTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCREL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE1 --------CSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFI :: :: ..: :::.::: : . : .:: . ::: .. .::::. ::.: CCDS73 YNKAGAHRCS-PCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFA 100 110 120 130 140 150 200 210 220 230 240 pF1KE1 QQAISYSSF--PFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYP-SGTCAYIQR . ::: : .: :: : . . ::: ::.:. .::.. .. : : : :. : CCDS73 ASQ-SYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHI--IIDVTSPRSRDCVAILN 160 170 180 190 200 250 260 270 pF1KE1 GAVYAENCILAAFSICQKKANLRAQ : .....: .:...:.. CCDS73 GMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD 210 220 230 240 273 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 22:43:34 2016 done: Sun Nov 6 22:43:35 2016 Total Scan time: 2.410 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]