Result of FASTA (ccds) for
pFN21AB8923
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8923, 270 aa
1>>>pF1KB8923 270 - 270 aa - 270 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9583+/-0.000855; mu= 1.3517+/- 0.052
mean_var=248.8582+/-51.302, 0's: 0 Z-trim(115.7): 137 B-trim: 0 in 0/52
Lambda= 0.081301
statistics sampled from 16170 (16319) to 16170 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.501), width: 16
Scan time: 2.850
The best scores are: opt bits E(32554)
CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 ( 270) 1854 229.4 2.1e-60
CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 ( 269) 1066 137.0 1.4e-32
CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 ( 264) 529 74.0 1.2e-13
CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 ( 251) 527 73.7 1.4e-13
CCDS8872.1 HOXC5 gene_id:3222|Hs108|chr12 ( 222) 524 73.3 1.6e-13
CCDS5405.1 HOXA4 gene_id:3201|Hs108|chr7 ( 320) 519 72.9 3.2e-13
CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 ( 255) 515 72.3 3.8e-13
CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 ( 224) 480 68.2 5.9e-12
CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 ( 235) 467 66.7 1.8e-11
CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 ( 233) 462 66.1 2.6e-11
CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 ( 153) 458 65.4 2.7e-11
>>CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 (270 aa)
initn: 1854 init1: 1854 opt: 1854 Z-score: 1198.0 bits: 229.4 E(32554): 2.1e-60
Smith-Waterman score: 1854; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270)
10 20 30 40 50 60
pF1KB8 MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK
190 200 210 220 230 240
250 260 270
pF1KB8 IWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
::::::::::::::::::::::::::::::
CCDS54 IWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
250 260 270
>>CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 (269 aa)
initn: 951 init1: 560 opt: 1066 Z-score: 698.5 bits: 137.0 E(32554): 1.4e-32
Smith-Waterman score: 1066; 62.3% identity (78.3% similar) in 281 aa overlap (1-270:1-269)
10 20 30 40 50 60
pF1KB8 MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG
::::::::: ::::::::::: :::. ::.: ..:: :.::.: :::.::::::::.::.
CCDS11 MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 --SGHFGS-GERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHG
:.:::. :: .:.. : :. :::. : :.: .:. :::. ..::: :
CCDS11 ASSSHFGAVGESSRAFPAPAQ----EPRFRQAASSCSLSSPESLPCT------NGDSH-G
70 80 90 100
120 130 140 150 160 170
pF1KB8 GKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPA---SSEQASAQSEP----SPAP
.: : :. : ...:.:. .. ..::. :.: . : : :: :: . ::
CCDS11 AKPSASSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAP
110 120 130 140 150 160
180 190 200 210 220
pF1KB8 PAQ-PQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIA
.: :::.::::::::::: . ::.:::::::::::::::::::::::::::::::::::
CCDS11 EGQTPQIFPWMRKLHISHD-MTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIA
170 180 190 200 210 220
230 240 250 260 270
pF1KB8 HALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
:::::::::::::::::::::::::::::::.:.::.::.:
CCDS11 HALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP
230 240 250 260
>>CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 (264 aa)
initn: 586 init1: 382 opt: 529 Z-score: 358.2 bits: 74.0 E(32554): 1.2e-13
Smith-Waterman score: 529; 49.2% identity (64.9% similar) in 185 aa overlap (96-267:54-231)
70 80 90 100 110
pF1KB8 SGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLP--------CSAVAPSPGSDSHHG
: : : : :... .::.. ::
CCDS88 SQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQ-GPGNSRGHG
30 40 50 60 70 80
120 130 140 150 160 170
pF1KB8 GKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIY
..: : . .. ::.. :: . : : ..:: : :: .:
CCDS88 -----PAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQP-APDHPSSAASKQPIVY
90 100 110 120 130
180 190 200 210 220 230
pF1KB8 PWMRKLHIS--HDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS
:::.:.:.: . : .: : ::.:::::: :.::::::::.::::::::::::::.::::
CCDS88 PWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLS
140 150 160 170 180 190
240 250 260 270
pF1KB8 ERQIKIWFQNRRMKWKKDNKL---KSMSMAAAGGAFRP
::::::::::::::::::..: : : ::.:
CCDS88 ERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQ
200 210 220 230 240 250
CCDS88 RAEDITRL
260
>>CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 (251 aa)
initn: 514 init1: 396 opt: 527 Z-score: 357.2 bits: 73.7 E(32554): 1.4e-13
Smith-Waterman score: 536; 44.3% identity (61.0% similar) in 228 aa overlap (49-267:23-234)
20 30 40 50 60 70
pF1KB8 YQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARS-YAASA
:. : . . :....:.: .: . :
CCDS11 MAMSSFLINSNYVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQRRESSFQPEA
10 20 30 40 50
80 90 100 110 120 130
pF1KB8 S----AAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAG
. :: . ::. : .: : : : : :: :: . : ::
CCDS11 GFGRRAACTVQRYA--ACRDPGPPPPPPPPPPPPPPPG----------LSPRAPAPPPAG
60 70 80 90 100
140 150 160 170 180
pF1KB8 STHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPA--QPQIYPWMRKLHIS--HDN
. : : ..: :. .:::. : .: .::::::.:.: . :
CCDS11 ALLPEP----GQRCEAVSSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMRKVHVSTVNPN
110 120 130 140 150
190 200 210 220 230 240
pF1KB8 IGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMK
.: : ::.:::::: :.::::::::.:::::::::.:::::::::::::::::::::::
CCDS11 YAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMK
160 170 180 190 200 210
250 260 270
pF1KB8 WKKDNKLKSMSMAAAGGAFRP
::::.:: . .. ..:.:
CCDS11 WKKDHKLPNTKIRSGGAAGSAGGPPGRPNGGPRAL
220 230 240 250
>>CCDS8872.1 HOXC5 gene_id:3222|Hs108|chr12 (222 aa)
initn: 523 init1: 410 opt: 524 Z-score: 356.0 bits: 73.3 E(32554): 1.6e-13
Smith-Waterman score: 625; 45.9% identity (66.4% similar) in 259 aa overlap (1-258:1-218)
10 20 30 40 50 60
pF1KB8 MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG
:::: .::: . :: : :.... :...:.:: ....:: :: :.:::.
CCDS88 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASE-------VQASRYCYG--GLDLSITFPP
10 20 30 40 50
70 80 90 100 110
pF1KB8 SGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAP-SPGSDSHHGGK
. .: .. ..::. : : .: : :. :.: : .:: .:: :.....
CCDS88 PAPSNS-LHGVDMAANPRAHPDRPACSAAAAPGHAPGRD-----EAAPLNPGMYSQKAAR
60 70 80 90 100
120 130 140 150 160 170
pF1KB8 NSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPW
.: : . .:: .. :.. : .. :.: :::: :::::
CCDS88 PAL------------------EERAKSSGEIKEEQAQTGQPAGLSQP-PAPP---QIYPW
110 120 130 140
180 190 200 210 220 230
pF1KB8 MRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQI
: :::.::.. .:::.::.::::::::::::::::::::::::::::. :::.::::
CCDS88 MTKLHMSHET----DGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQI
150 160 170 180 190
240 250 260 270
pF1KB8 KIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
::::::::::::::.:.::
CCDS88 KIWFQNRRMKWKKDSKMKSKEAL
200 210 220
>>CCDS5405.1 HOXA4 gene_id:3201|Hs108|chr7 (320 aa)
initn: 491 init1: 393 opt: 519 Z-score: 350.8 bits: 72.9 E(32554): 3.2e-13
Smith-Waterman score: 519; 46.3% identity (66.2% similar) in 201 aa overlap (73-267:90-287)
50 60 70 80 90 100
pF1KB8 GRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPR-YSQPATSTHSPQPDPL
: : ..: : : : :. . :::.
CCDS54 LPHAGGGREPTASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQP
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 PCSAVAPSPGSDSHHGGKNSLSN--SSGASADAGSTHISSREGV-GTASGAEEDAPASSE
: .: .:. : . : . .: . : :. . . .. :. .:. .:::
CCDS54 PAQAKGPAHGLHASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGVPAGG--SAPACPL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 QASAQSEPSPAPPAQPQIYPWMRKLHISHDN--IGGPEGKRARTAYTRYQTLELEKEFHF
. .: : .: .::::.:.:.: : .: : ::.:::::: :.:::::::::
CCDS54 LLADKS-PLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 NRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
::::::::::::::.:::::::.::::::::::::::.:: . .: ....:
CCDS54 NRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPPGK
240 250 260 270 280 290
CCDS54 AQTQSPHLHPHPHPSTSTPVPSSI
300 310 320
>>CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 (255 aa)
initn: 442 init1: 414 opt: 515 Z-score: 349.5 bits: 72.3 E(32554): 3.8e-13
Smith-Waterman score: 515; 46.6% identity (65.7% similar) in 204 aa overlap (62-256:27-215)
40 50 60 70 80 90
pF1KB8 EQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPRYSQPAT
:..: . : :...:..: .: :.
CCDS22 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGE-QGADYYGGGAQGADFQP----PGL
10 20 30 40 50
100 110 120 130 140
pF1KB8 STHSPQPD--PLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGA
:.:: : .. .:.::: :... .. :. : .. : :
CCDS22 ---YPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGG-------HYAAPGEPCPAPPA
60 70 80 90 100
150 160 170 180 190 200
pF1KB8 EEDAPASSEQASAQSEPSPAPPA----QPQI-YPWMRKLHIS--HDNIGGPEGKRARTAY
:: . .: .::.:. : . :: . ::::.:.:.. . : : : ::.::::
CCDS22 PPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAY
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB8 TRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMA
:: :.:::::::::::::::::::::::.::::::::::::::::::::::.::
CCDS22 TRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGR
170 180 190 200 210 220
270
pF1KB8 AAGGAFRP
CCDS22 SSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL
230 240 250
>>CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 (224 aa)
initn: 528 init1: 448 opt: 480 Z-score: 328.1 bits: 68.2 E(32554): 5.9e-12
Smith-Waterman score: 482; 46.0% identity (67.4% similar) in 187 aa overlap (95-264:30-215)
70 80 90 100 110 120
pF1KB8 GSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPL---PCSAVAPSPGSDSHHGGKNS
: ::: : . .:.::.:. . ..
CCDS11 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYP-APYGPGPGQDKGFATSSY
10 20 30 40 50
130 140 150 160 170
pF1KB8 LSNSSG-----ASADAGSTHISSRE--GVGTASGAEEDAPASSE--QASAQSEPSPAPPA
..: : : : . :: .. . :::.:. : : ... .. : .
CCDS11 YPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSVFGET
60 70 80 90 100 110
180 190 200 210 220
pF1KB8 QPQ-----IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIE
. : .::::.... ... :: :.:.: .::::::::::::::.:::::::::::
CCDS11 EEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIE
120 130 140 150 160 170
230 240 250 260 270
pF1KB8 IAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
:::::::.:::::::::::::::::..:: : :. .:
CCDS11 IAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE
180 190 200 210 220
>>CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 (235 aa)
initn: 455 init1: 430 opt: 467 Z-score: 319.6 bits: 66.7 E(32554): 1.8e-11
Smith-Waterman score: 486; 47.4% identity (68.4% similar) in 196 aa overlap (75-267:38-213)
50 60 70 80 90 100
pF1KB8 YGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPR-YSQPATSTHSPQPDPLPC
.. .:: :. : :: : .::: . .
CCDS88 PSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTP---FYSPQENVVFS
10 20 30 40 50 60
110 120 130 140 150 160
pF1KB8 SAVAPSP-GSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASA
:. .: ::.: . :. ::: . : .: .. .: :::: .
CCDS88 SSRGPYDYGSNSFYQEKDMLSNCRQNTL-----------GHNTQTSIAQDF--SSEQ--G
70 80 90 100
170 180 190 200 210 220
pF1KB8 QSEPSPAPPAQPQIYPWMRKLHISHDNIG-GPEGKRARTAYTRYQTLELEKEFHFNRYLT
.. :. :. ::::::.... ::...: : . .:.: :.::::::::::::::::::
CCDS88 RTAPQDQK-ASIQIYPWMQRMN-SHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLT
110 120 130 140 150 160
230 240 250 260 270
pF1KB8 RRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
::::::::.::::.:::::::::::::::::...: : ...:::
CCDS88 RRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREE
170 180 190 200 210 220
CCDS88 TEEEKQKE
230
>>CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 (233 aa)
initn: 492 init1: 444 opt: 462 Z-score: 316.4 bits: 66.1 E(32554): 2.6e-11
Smith-Waterman score: 462; 45.3% identity (66.1% similar) in 192 aa overlap (71-256:36-216)
50 60 70 80 90
pF1KB8 HSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAAS--ASAAPAEPRYSQPATSTHSPQP
: . :: ::. : . :..: .: .
CCDS54 VNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLP-DKTYTSPCFYQQSNSV
10 20 30 40 50 60
100 110 120 130 140 150
pF1KB8 DPLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTA---SGAEEDAP-
: :. .. :.. .. :. :::: .:: ....: : : .. :
CCDS54 --LACNRASYEYGASCFYSDKDL----SGASP-SGS---GKQRGPGDYLHFSPEQQYKPD
70 80 90 100 110
160 170 180 190 200 210
pF1KB8 ASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEF
.:: :..: . . .::::.... . : .:.:.: .:::::::::::::
CCDS54 SSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEF
120 130 140 150 160 170
220 230 240 250 260 270
pF1KB8 HFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
:::::::::::::::.::::.:::::::::::::::::.:::
CCDS54 HFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE
180 190 200 210 220 230
270 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:02:31 2016 done: Sat Nov 5 20:02:32 2016
Total Scan time: 2.850 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]