Result of FASTA (omim) for
pFN21AB7975
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7975, 427 aa
1>>>pF1KB7975 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3957+/-0.000318; mu= 18.6169+/- 0.020
mean_var=88.6617+/-17.904, 0's: 0 Z-trim(117.4): 12 B-trim: 60 in 1/53
Lambda= 0.136209
statistics sampled from 29381 (29393) to 29381 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.345), width: 16
Scan time: 9.260
The best scores are: opt bits E(85289)
NP_079491 (OMIM: 600462,608109) tRNA pseudouridine ( 427) 2931 585.7 7.4e-167
NP_001002019 (OMIM: 600462,608109) tRNA pseudourid ( 399) 2729 546.0 6.3e-155
NP_001002020 (OMIM: 600462,608109) tRNA pseudourid ( 399) 2729 546.0 6.3e-155
XP_011537070 (OMIM: 600462,608109) PREDICTED: tRNA ( 294) 1990 400.7 2.6e-111
XP_011537071 (OMIM: 600462,608109) PREDICTED: tRNA ( 216) 1039 213.7 3.7e-55
XP_005271745 (OMIM: 616283,617051) PREDICTED: tRNA ( 176) 165 41.9 0.0016
NP_112597 (OMIM: 616283,617051) tRNA pseudouridine ( 481) 165 42.2 0.0034
>>NP_079491 (OMIM: 600462,608109) tRNA pseudouridine syn (427 aa)
initn: 2931 init1: 2931 opt: 2931 Z-score: 3116.6 bits: 585.7 E(85289): 7.4e-167
Smith-Waterman score: 2931; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB7 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
370 380 390 400 410 420
pF1KB7 EGDGDTD
:::::::
NP_079 EGDGDTD
>>NP_001002019 (OMIM: 600462,608109) tRNA pseudouridine (399 aa)
initn: 2729 init1: 2729 opt: 2729 Z-score: 2902.5 bits: 546.0 E(85289): 6.3e-155
Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 399 aa overlap (29-427:1-399)
10 20 30 40 50 60
pF1KB7 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
::::::::::::::::::::::::::::::::
NP_001 MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
10 20 30
70 80 90 100 110 120
pF1KB7 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
340 350 360 370 380 390
pF1KB7 EGDGDTD
:::::::
NP_001 EGDGDTD
>>NP_001002020 (OMIM: 600462,608109) tRNA pseudouridine (399 aa)
initn: 2729 init1: 2729 opt: 2729 Z-score: 2902.5 bits: 546.0 E(85289): 6.3e-155
Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 399 aa overlap (29-427:1-399)
10 20 30 40 50 60
pF1KB7 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
::::::::::::::::::::::::::::::::
NP_001 MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
10 20 30
70 80 90 100 110 120
pF1KB7 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
340 350 360 370 380 390
pF1KB7 EGDGDTD
:::::::
NP_001 EGDGDTD
>>XP_011537070 (OMIM: 600462,608109) PREDICTED: tRNA pse (294 aa)
initn: 1990 init1: 1990 opt: 1990 Z-score: 2119.4 bits: 400.7 E(85289): 2.6e-111
Smith-Waterman score: 1990; 100.0% identity (100.0% similar) in 294 aa overlap (134-427:1-294)
110 120 130 140 150 160
pF1KB7 VGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLI
::::::::::::::::::::::::::::::
XP_011 MRKMSFQRCARTDKGVSAAGQVVSLKVWLI
10 20 30
170 180 190 200 210 220
pF1KB7 DDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYR
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB7 LSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB7 VKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKY
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB7 NQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATA
220 230 240 250 260 270
410 420
pF1KB7 LTAGGTGAKVPSPLEGSEGDGDTD
::::::::::::::::::::::::
XP_011 LTAGGTGAKVPSPLEGSEGDGDTD
280 290
>>XP_011537071 (OMIM: 600462,608109) PREDICTED: tRNA pse (216 aa)
initn: 1039 init1: 1039 opt: 1039 Z-score: 1111.2 bits: 213.7 E(85289): 3.7e-55
Smith-Waterman score: 1039; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KB7 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
:::::::::::::::::::::::::::
XP_011 VRSGCIPENHGEDMRKMSFQRCARTDKSQDLILLPRLECSGMIMAHCSLKLLGSSNPPAS
130 140 150 160 170 180
>>XP_005271745 (OMIM: 616283,617051) PREDICTED: tRNA pse (176 aa)
initn: 156 init1: 108 opt: 165 Z-score: 184.1 bits: 41.9 E(85289): 0.0016
Smith-Waterman score: 165; 39.5% identity (71.1% similar) in 76 aa overlap (83-158:62-130)
60 70 80 90 100 110
pF1KB7 AGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTI
.:...: .:: : ::.:. . .... ::
XP_005 QAKNKEDSNIRENSAGAGKTKRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNN--TI
40 50 60 70 80
120 130 140 150 160 170
pF1KB7 EDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINS
:. : ::... . :. . ...::.:::::::: :::.::
XP_005 EEKLFEALTKTRLV-----ESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSED
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB7 HLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQV
XP_005 FNVKEEANAAAEEIRYTHILNRYGCRISSSLI
150 160 170
>>NP_112597 (OMIM: 616283,617051) tRNA pseudouridine(38/ (481 aa)
initn: 253 init1: 108 opt: 165 Z-score: 178.4 bits: 42.2 E(85289): 0.0034
Smith-Waterman score: 270; 25.4% identity (53.8% similar) in 342 aa overlap (83-396:62-374)
60 70 80 90 100 110
pF1KB7 AGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTI
.:...: .:: : ::.:. . .... ::
NP_112 QAKNKEDSNIRENSAGAGKTKRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNN--TI
40 50 60 70 80
120 130 140 150 160
pF1KB7 EDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLI-----D---
:. : ::... . :. . ...::.:::::::: :::.:: . :
NP_112 EEKLFEALTKTRLV-----ESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSED
90 100 110 120 130 140
170 180 190 200 210
pF1KB7 -DILEKIN--------SH-----LPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAF
.. :. : .: :: ::::. : .:... : ::: :..: .
NP_112 FNVKEEANAAAEEIRYTHILNRVLPPDIRILAWAPVEPSFSARFSCLERTYRYFFPRADL
150 160 170 180 190 200
220 230 240 250 260
pF1KB7 AHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHN--FTSQKG--PQDPSACRYILEM
: . : .... .... .. .:. ::. ...: :.:. :.
NP_112 DIVTMDYAAQKY-VGTHDFRNLCKM-DVANGVINFQRTILSAQVQLVGQSPGEGRW----
210 220 230 240 250
270 280 290 300 310 320
pF1KB7 YCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVP
.::: .. ..: ::.:..::.: :.... : .:. .... . :: :
NP_112 --QEPF-----QLCQFEVTGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKN--P
260 270 280 290 300
330 340 350 360 370 380
pF1KB7 KAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWA--QEEGKVAAFKEEHIYPTIIGTERDE
. : ....: . :. .: : . : :: . . .... . .
NP_112 QKPQYSMAVE-FPLVLYDCKFEN------VKWIYDQEAQEFNITHLQQLWANHAVKTHML
310 320 330 340 350 360
390 400 410 420
pF1KB7 RSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD
:: : :.:.:.
NP_112 YSMLQGLDTVPVPCGIGPKMDGMTEWGNVKPSVIKQTSAFVEGVKMRTYKPLMDRPKCQG
370 380 390 400 410 420
427 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:48:57 2016 done: Sat Nov 5 14:48:58 2016
Total Scan time: 9.260 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]