Result of FASTA (omim) for
pFN21AE1412
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1412, 149 aa
1>>>pF1KE1412 149 - 149 aa - 149 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0203+/-0.000403; mu= 14.6279+/- 0.025
mean_var=109.1916+/-22.285, 0's: 0 Z-trim(115.0): 279 B-trim: 765 in 3/51
Lambda= 0.122738
statistics sampled from 24762 (25140) to 24762 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.295), width: 16
Scan time: 4.990
The best scores are: opt bits E(85289)
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 970 181.8 3.7e-46
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 855 161.4 4.9e-40
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 855 161.4 4.9e-40
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 855 161.4 4.9e-40
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 855 161.4 4.9e-40
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 848 160.2 1.2e-39
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 848 160.3 1.4e-39
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 646 124.2 5.8e-29
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 646 124.2 5.8e-29
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 646 124.2 5.8e-29
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 646 124.2 5.8e-29
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 646 124.2 5.8e-29
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 646 124.2 5.8e-29
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 646 124.2 5.8e-29
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 494 97.5 9.4e-21
NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 488 96.4 1.9e-20
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 485 95.9 2.7e-20
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 478 94.7 6.7e-20
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 466 92.5 2.6e-19
NP_059118 (OMIM: 605183) calmodulin-like protein 5 ( 146) 465 92.3 3e-19
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 430 86.1 2.2e-17
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 430 86.1 2.2e-17
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 411 82.9 2.6e-16
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 411 82.9 2.8e-16
NP_004267 (OMIM: 605563) calcium-binding protein 1 ( 167) 409 82.5 3.1e-16
NP_112482 (OMIM: 605563) calcium-binding protein 1 ( 227) 409 82.7 3.8e-16
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 407 82.1 4e-16
NP_001028849 (OMIM: 605563) calcium-binding protei ( 370) 409 82.9 5.1e-16
NP_002466 (OMIM: 609930) myosin light chain 6B [Ho ( 208) 406 82.1 5.2e-16
NP_001186558 (OMIM: 609930) myosin light chain 6B ( 208) 406 82.1 5.2e-16
NP_524146 (OMIM: 160780) myosin light chain 1/3, s ( 150) 404 81.5 5.4e-16
NP_524144 (OMIM: 160780) myosin light chain 1/3, s ( 194) 404 81.7 6.4e-16
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 402 81.3 7.6e-16
NP_062829 (OMIM: 607315) calcium-binding protein 5 ( 173) 398 80.6 1.2e-15
XP_016882481 (OMIM: 607315) PREDICTED: calcium-bin ( 284) 398 80.8 1.7e-15
NP_057450 (OMIM: 607314,614899) calcium-binding pr ( 220) 391 79.4 3.4e-15
NP_001305425 (OMIM: 607314,614899) calcium-binding ( 226) 391 79.5 3.5e-15
NP_000249 (OMIM: 160790,608751) myosin light chain ( 195) 387 78.7 5.1e-15
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 384 78.1 6.9e-15
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 384 78.1 6.9e-15
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 384 78.1 6.9e-15
XP_016875728 (OMIM: 605563) PREDICTED: calcium-bin ( 202) 379 77.3 1.4e-14
XP_016873514 (OMIM: 608965,610427) PREDICTED: calc ( 170) 378 77.0 1.4e-14
NP_001287825 (OMIM: 608965,610427) calcium-binding ( 170) 378 77.0 1.4e-14
XP_011543485 (OMIM: 608965,610427) PREDICTED: calc ( 170) 378 77.0 1.4e-14
NP_001287824 (OMIM: 608965,610427) calcium-binding ( 170) 378 77.0 1.4e-14
XP_016875727 (OMIM: 605563) PREDICTED: calcium-bin ( 262) 379 77.4 1.6e-14
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 376 76.6 1.8e-14
NP_660201 (OMIM: 608965,610427) calcium-binding pr ( 275) 378 77.3 1.9e-14
XP_011543483 (OMIM: 608965,610427) PREDICTED: calc ( 295) 378 77.3 2e-14
>>NP_005176 (OMIM: 114184) calmodulin-like protein 3 [Ho (149 aa)
initn: 970 init1: 970 opt: 970 Z-score: 949.8 bits: 181.8 E(85289): 3.7e-46
Smith-Waterman score: 970; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KE1 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
70 80 90 100 110 120
130 140
pF1KE1 EVDEMIRAADTDGDGQVNYEEFVRVLVSK
:::::::::::::::::::::::::::::
NP_005 EVDEMIRAADTDGDGQVNYEEFVRVLVSK
130 140
>>NP_008819 (OMIM: 114180,614916,616247) calmodulin [Hom (149 aa)
initn: 1125 init1: 855 opt: 855 Z-score: 839.7 bits: 161.4 E(85289): 4.9e-40
Smith-Waterman score: 855; 84.6% identity (96.0% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KE1 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
:::::::::..::::::::::::::: :::.::::::::::::::::::.::..:.: ::
NP_008 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
:::.:::::: ::::::::::.:::::::::::::::::..:::::::::: :::::.::
NP_008 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
70 80 90 100 110 120
130 140
pF1KE1 EVDEMIRAADTDGDGQVNYEEFVRVLVSK
::::::: :: ::::::::::::.....:
NP_008 EVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140
>>NP_001316851 (OMIM: 114183) calmodulin isoform 1 [Homo (149 aa)
initn: 1125 init1: 855 opt: 855 Z-score: 839.7 bits: 161.4 E(85289): 4.9e-40
Smith-Waterman score: 855; 84.6% identity (96.0% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KE1 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
:::::::::..::::::::::::::: :::.::::::::::::::::::.::..:.: ::
NP_001 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
:::.:::::: ::::::::::.:::::::::::::::::..:::::::::: :::::.::
NP_001 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
70 80 90 100 110 120
130 140
pF1KE1 EVDEMIRAADTDGDGQVNYEEFVRVLVSK
::::::: :: ::::::::::::.....:
NP_001 EVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140
>>NP_005175 (OMIM: 114183) calmodulin isoform 1 [Homo sa (149 aa)
initn: 1125 init1: 855 opt: 855 Z-score: 839.7 bits: 161.4 E(85289): 4.9e-40
Smith-Waterman score: 855; 84.6% identity (96.0% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KE1 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
:::::::::..::::::::::::::: :::.::::::::::::::::::.::..:.: ::
NP_005 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
:::.:::::: ::::::::::.:::::::::::::::::..:::::::::: :::::.::
NP_005 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
70 80 90 100 110 120
130 140
pF1KE1 EVDEMIRAADTDGDGQVNYEEFVRVLVSK
::::::: :: ::::::::::::.....:
NP_005 EVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140
>>NP_001734 (OMIM: 114182,616249) calmodulin isoform 2 [ (149 aa)
initn: 1125 init1: 855 opt: 855 Z-score: 839.7 bits: 161.4 E(85289): 4.9e-40
Smith-Waterman score: 855; 84.6% identity (96.0% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KE1 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG
:::::::::..::::::::::::::: :::.::::::::::::::::::.::..:.: ::
NP_001 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 NGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDE
:::.:::::: ::::::::::.:::::::::::::::::..:::::::::: :::::.::
NP_001 NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE
70 80 90 100 110 120
130 140
pF1KE1 EVDEMIRAADTDGDGQVNYEEFVRVLVSK
::::::: :: ::::::::::::.....:
NP_001 EVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140
>>XP_006720321 (OMIM: 114180,614916,616247) PREDICTED: c (150 aa)
initn: 1118 init1: 848 opt: 848 Z-score: 833.0 bits: 160.2 E(85289): 1.2e-39
Smith-Waterman score: 848; 84.5% identity (95.9% similar) in 148 aa overlap (2-149:3-150)
10 20 30 40 50
pF1KE1 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRD
::::::::..::::::::::::::: :::.::::::::::::::::::.::..:.: :
XP_006 MQADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 GNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSD
::::.:::::: ::::::::::.:::::::::::::::::..:::::::::: :::::.:
XP_006 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD
70 80 90 100 110 120
120 130 140
pF1KE1 EEVDEMIRAADTDGDGQVNYEEFVRVLVSK
:::::::: :: ::::::::::::.....:
XP_006 EEVDEMIREADIDGDGQVNYEEFVQMMTAK
130 140 150
>>NP_001292553 (OMIM: 114182,616249) calmodulin isoform (197 aa)
initn: 1118 init1: 848 opt: 848 Z-score: 831.7 bits: 160.3 E(85289): 1.4e-39
Smith-Waterman score: 848; 84.5% identity (95.9% similar) in 148 aa overlap (2-149:50-197)
10 20 30
pF1KE1 MADQLTEEQVTEFKEAFSLFDKDGDGCITTR
::::::::..::::::::::::::: :::.
NP_001 GCVVASRKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDGDGTITTK
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 ELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFR
::::::::::::::::::.::..:.: :::::.:::::: ::::::::::.:::::::::
NP_001 ELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFR
80 90 100 110 120 130
100 110 120 130 140
pF1KE1 VFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLVSK
::::::::..:::::::::: :::::.::::::::: :: ::::::::::::.....:
NP_001 VFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
140 150 160 170 180 190
>>NP_001292555 (OMIM: 114182,616249) calmodulin isoform (113 aa)
initn: 730 init1: 646 opt: 646 Z-score: 641.0 bits: 124.2 E(85289): 5.8e-29
Smith-Waterman score: 646; 83.2% identity (95.6% similar) in 113 aa overlap (37-149:1-113)
10 20 30 40 50 60
pF1KE1 EEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDF
:::::::::::::.::..:.: :::::.::
NP_001 MRSLGQNPTEAELQDMINEVDADGNGTIDF
10 20 30
70 80 90 100 110 120
pF1KE1 PEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMI
:::: ::::::::::.:::::::::::::::::..:::::::::: :::::.::::::::
NP_001 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI
40 50 60 70 80 90
130 140
pF1KE1 RAADTDGDGQVNYEEFVRVLVSK
: :: ::::::::::::.....:
NP_001 READIDGDGQVNYEEFVQMMTAK
100 110
>>NP_001316850 (OMIM: 114183) calmodulin isoform 2 [Homo (113 aa)
initn: 730 init1: 646 opt: 646 Z-score: 641.0 bits: 124.2 E(85289): 5.8e-29
Smith-Waterman score: 646; 83.2% identity (95.6% similar) in 113 aa overlap (37-149:1-113)
10 20 30 40 50 60
pF1KE1 EEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDF
:::::::::::::.::..:.: :::::.::
NP_001 MRSLGQNPTEAELQDMINEVDADGNGTIDF
10 20 30
70 80 90 100 110 120
pF1KE1 PEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMI
:::: ::::::::::.:::::::::::::::::..:::::::::: :::::.::::::::
NP_001 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI
40 50 60 70 80 90
130 140
pF1KE1 RAADTDGDGQVNYEEFVRVLVSK
: :: ::::::::::::.....:
NP_001 READIDGDGQVNYEEFVQMMTAK
100 110
>>NP_001316853 (OMIM: 114183) calmodulin isoform 2 [Homo (113 aa)
initn: 730 init1: 646 opt: 646 Z-score: 641.0 bits: 124.2 E(85289): 5.8e-29
Smith-Waterman score: 646; 83.2% identity (95.6% similar) in 113 aa overlap (37-149:1-113)
10 20 30 40 50 60
pF1KE1 EEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDF
:::::::::::::.::..:.: :::::.::
NP_001 MRSLGQNPTEAELQDMINEVDADGNGTIDF
10 20 30
70 80 90 100 110 120
pF1KE1 PEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMI
:::: ::::::::::.:::::::::::::::::..:::::::::: :::::.::::::::
NP_001 PEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMI
40 50 60 70 80 90
130 140
pF1KE1 RAADTDGDGQVNYEEFVRVLVSK
: :: ::::::::::::.....:
NP_001 READIDGDGQVNYEEFVQMMTAK
100 110
149 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:07:58 2016 done: Mon Nov 7 00:07:59 2016
Total Scan time: 4.990 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]