Result of FASTA (omim) for
pFN21AB5673
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5673, 550 aa
1>>>pF1KB5673 550 - 550 aa - 550 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2558+/-0.000452; mu= 19.0649+/- 0.028
mean_var=71.1785+/-14.990, 0's: 0 Z-trim(110.0): 68 B-trim: 0 in 0/48
Lambda= 0.152020
statistics sampled from 18177 (18224) to 18177 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.561), E-opt: 0.2 (0.214), width: 16
Scan time: 9.110
The best scores are: opt bits E(85289)
XP_011508213 (OMIM: 102642) PREDICTED: sterol O-ac ( 550) 3753 832.9 0
NP_003092 (OMIM: 102642) sterol O-acyltransferase ( 550) 3753 832.9 0
NP_001239440 (OMIM: 102642) sterol O-acyltransfera ( 492) 3385 752.2 8.7e-217
NP_001239441 (OMIM: 102642) sterol O-acyltransfera ( 485) 3342 742.7 5.9e-214
XP_011508214 (OMIM: 102642) PREDICTED: sterol O-ac ( 331) 2172 486.0 7.7e-137
NP_003569 (OMIM: 601311) sterol O-acyltransferase ( 522) 1711 385.0 3e-106
XP_011537151 (OMIM: 601311) PREDICTED: sterol O-ac ( 502) 1662 374.3 5e-103
XP_011537152 (OMIM: 601311) PREDICTED: sterol O-ac ( 466) 1487 335.9 1.7e-91
XP_011537153 (OMIM: 601311) PREDICTED: sterol O-ac ( 278) 516 122.8 1.4e-27
XP_011515658 (OMIM: 604900,615863) PREDICTED: diac ( 431) 405 98.6 4.3e-20
NP_036211 (OMIM: 604900,615863) diacylglycerol O-a ( 488) 405 98.6 4.8e-20
>>XP_011508213 (OMIM: 102642) PREDICTED: sterol O-acyltr (550 aa)
initn: 3753 init1: 3753 opt: 3753 Z-score: 4448.5 bits: 832.9 E(85289): 0
Smith-Waterman score: 3753; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550)
10 20 30 40 50 60
pF1KB5 MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 YVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 NVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 FFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVR
490 500 510 520 530 540
550
pF1KB5 PRSWTCRYVF
::::::::::
XP_011 PRSWTCRYVF
550
>>NP_003092 (OMIM: 102642) sterol O-acyltransferase 1 is (550 aa)
initn: 3753 init1: 3753 opt: 3753 Z-score: 4448.5 bits: 832.9 E(85289): 0
Smith-Waterman score: 3753; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550)
10 20 30 40 50 60
pF1KB5 MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 YVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 NVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 FFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVR
490 500 510 520 530 540
550
pF1KB5 PRSWTCRYVF
::::::::::
NP_003 PRSWTCRYVF
550
>>NP_001239440 (OMIM: 102642) sterol O-acyltransferase 1 (492 aa)
initn: 3385 init1: 3385 opt: 3385 Z-score: 4013.0 bits: 752.2 E(85289): 8.7e-217
Smith-Waterman score: 3385; 100.0% identity (100.0% similar) in 491 aa overlap (60-550:2-492)
30 40 50 60 70 80
pF1KB5 AKESLETPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDN
::::::::::::::::::::::::::::::
NP_001 MELKPFFMKEVGSHFDDFVTNLIEKSASLDN
10 20 30
90 100 110 120 130 140
pF1KB5 GGCALTTFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGCALTTFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB5 ILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATG
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB5 YSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB5 FVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQ
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB5 VFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWL
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB5 NAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAM
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB5 LAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFL
400 410 420 430 440 450
510 520 530 540 550
pF1KB5 GNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
:::::::::::::::::::::::::::::::::::::::::
NP_001 GNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
460 470 480 490
>>NP_001239441 (OMIM: 102642) sterol O-acyltransferase 1 (485 aa)
initn: 3342 init1: 3342 opt: 3342 Z-score: 3962.2 bits: 742.7 E(85289): 5.9e-214
Smith-Waterman score: 3342; 100.0% identity (100.0% similar) in 485 aa overlap (66-550:1-485)
40 50 60 70 80 90
pF1KB5 TPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALT
::::::::::::::::::::::::::::::
NP_001 MKEVGSHFDDFVTNLIEKSASLDNGGCALT
10 20 30
100 110 120 130 140 150
pF1KB5 TFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILS
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 TLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 PLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENV
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB5 PRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFF
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB5 YVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEM
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB5 LRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAV
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB5 SAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLL
400 410 420 430 440 450
520 530 540 550
pF1KB5 CFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
:::::::::::::::::::::::::::::::::::
NP_001 CFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
460 470 480
>>XP_011508214 (OMIM: 102642) PREDICTED: sterol O-acyltr (331 aa)
initn: 2172 init1: 2172 opt: 2172 Z-score: 2577.7 bits: 486.0 E(85289): 7.7e-137
Smith-Waterman score: 2172; 100.0% identity (100.0% similar) in 330 aa overlap (1-330:1-330)
10 20 30 40 50 60
pF1KB5 MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 YVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSAR
::::::::::::::::::::::::::::::
XP_011 LFAPTLIYRDSYPRNPTVRWGYVAMKFAQVC
310 320 330
>>NP_003569 (OMIM: 601311) sterol O-acyltransferase 2 [H (522 aa)
initn: 1748 init1: 1196 opt: 1711 Z-score: 2028.5 bits: 385.0 E(85289): 3e-106
Smith-Waterman score: 1711; 55.7% identity (80.1% similar) in 433 aa overlap (116-546:96-520)
90 100 110 120 130 140
pF1KB5 SLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGK--IFIARRSLLDELLEVDHIRTIYH
: :: .:: :.::::::.::.:.:::::
NP_003 RAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYH
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB5 MFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLF
:::: : .::.:::..:.::::::.:::.:: ..::..: .. :: :::::. .:: .
NP_003 MFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQAL
130 140 150 160 170 180
210 220 230 240 250 260
pF1KB5 QHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRF
. :: : .. : : .. . :: :..:.. . :::::: ...:::.::
NP_003 RLWARGTWTQATGL------GCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRF
190 200 210 220 230
270 280 290 300 310 320
pF1KB5 VMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYV
.::..::.:: :: .: . ... . :. ..:::::: ::::::..:::.: :::.::
NP_003 LMKSYSFLREAVPGTLRA--RRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYV
240 250 260 270 280 290
330 340 350 360 370 380
pF1KB5 AMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFA
: .:::..:: .:. .:. :::.:.: :...::::.:.::: .... :::...:.: :::
NP_003 AKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFA
300 310 320 330 340 350
390 400 410 420 430 440
pF1KB5 FLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKR
:::::::::::::::::::::.:::::::.:::::::::::::::: :.:.: : ... :
NP_003 FLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGAR
360 370 380 390 400 410
450 460 470 480 490 500
pF1KB5 FKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLM
...:::.:: ::::.::: . :.:::::...::. .: .::...:.: : :::::
NP_003 ARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLM
420 430 440 450 460 470
510 520 530 540 550
pF1KB5 WTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
:: ::::.:. . .: ::::::.:::: . :: : ::::.:
NP_003 WTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT
480 490 500 510 520
>>XP_011537151 (OMIM: 601311) PREDICTED: sterol O-acyltr (502 aa)
initn: 1700 init1: 1196 opt: 1662 Z-score: 1970.7 bits: 374.3 E(85289): 5e-103
Smith-Waterman score: 1664; 54.6% identity (78.9% similar) in 432 aa overlap (115-546:84-500)
90 100 110 120 130 140
pF1KB5 ASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHM
:: : :: .::.::.:.::::::
XP_011 EQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPG-------SLSSELMEVQHFRTIYHM
60 70 80 90 100
150 160 170 180 190 200
pF1KB5 FIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQ
::: : .::.:::..:.::::::.:::.:: ..::..: .. :: :::::. .:: ..
XP_011 FIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALR
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB5 HWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFV
:: : .. : : .. . :: :..:.. . :::::: ...:::.::.
XP_011 LWARGTWTQATGL------GCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFL
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB5 MKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVA
::..::.:: :: .: . ... . :. ..:::::: ::::::..:::.: :::.:::
XP_011 MKSYSFLREAVPGTLRA--RRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVA
230 240 250 260 270
330 340 350 360 370 380
pF1KB5 MKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAF
.:::..:: .:. .:. :::.:.: :...::::.:.::: .... :::...:.: ::::
XP_011 KNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAF
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB5 LHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRF
::::::::::::::::::::.:::::::.:::::::::::::::: :.:.: : ... :
XP_011 LHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARA
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB5 KSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMW
...:::.:: ::::.::: . :.:::::...::. .: .::...:.: : ::::::
XP_011 RGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMW
400 410 420 430 440 450
510 520 530 540 550
pF1KB5 TSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
: ::::.:. . .: ::::::.:::: . :: : ::::.:
XP_011 TMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT
460 470 480 490 500
>>XP_011537152 (OMIM: 601311) PREDICTED: sterol O-acyltr (466 aa)
initn: 1496 init1: 1196 opt: 1487 Z-score: 1763.7 bits: 335.9 E(85289): 1.7e-91
Smith-Waterman score: 1487; 54.1% identity (79.3% similar) in 381 aa overlap (166-546:92-464)
140 150 160 170 180 190
pF1KB5 DHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLST
::.:::.:: ..::..: .. :: :::::
XP_011 ELLDRAMREAIQSYPSQDKPLPPPPPGSLSRLLLEFDLLIFSFGQLPLALVTWVPMFLST
70 80 90 100 110 120
200 210 220 230 240 250
pF1KB5 FSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFI
. .:: .. :: : .. : : .. . :: :..:.. . :::::: .
XP_011 LLAPYQALRLWARGTWTQATGL------GCALLAAHAVVLCALPVHVAVEHQLPPASRCV
130 140 150 160 170
260 270 280 290 300 310
pF1KB5 IIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRN
..:::.::.::..::.:: :: .: . ... . :. ..:::::: ::::::..:::.
XP_011 LVFEQVRFLMKSYSFLREAVPGTLRA--RRGEGIQAPSFSSYLYFLFCPTLIYRETYPRT
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB5 PTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVL
: :::.::: .:::..:: .:. .:. :::.:.: :...::::.:.::: .... :::..
XP_011 PYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIF
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB5 ILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKD
.:.: ::::::::::::::::::::::::.:::::::.:::::::::::::::: :.:.:
XP_011 MLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQD
300 310 320 330 340 350
440 450 460 470 480 490
pF1KB5 FLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRK
: ... : ...:::.:: ::::.::: . :.:::::...::. .: .::...:.:
XP_011 GLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRT
360 370 380 390 400 410
500 510 520 530 540 550
pF1KB5 KPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
: ::::::: ::::.:. . .: ::::::.:::: . :: : ::::.:
XP_011 GPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT
420 430 440 450 460
>>XP_011537153 (OMIM: 601311) PREDICTED: sterol O-acyltr (278 aa)
initn: 547 init1: 363 opt: 516 Z-score: 616.0 bits: 122.8 E(85289): 1.4e-27
Smith-Waterman score: 516; 48.8% identity (74.1% similar) in 170 aa overlap (116-283:96-259)
90 100 110 120 130 140
pF1KB5 SLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGK--IFIARRSLLDELLEVDHIRTIYH
: :: .:: :.::::::.::.:.:::::
XP_011 RAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYH
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB5 MFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLF
:::: : .::.:::..:.::::::.:::.:: ..::..: .. :: :::::. .:: .
XP_011 MFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQAL
130 140 150 160 170 180
210 220 230 240 250 260
pF1KB5 QHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRF
. :: : .. : : .. . :: :..:.. . :::::: ...:::.::
XP_011 RLWARGTWTQATGL------GCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRF
190 200 210 220 230
270 280 290 300 310 320
pF1KB5 VMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYV
.::..::.:: :: .: . .
XP_011 LMKSYSFLREAVPGTLRARRANRKARGEQKRWENGRSAE
240 250 260 270
>>XP_011515658 (OMIM: 604900,615863) PREDICTED: diacylgl (431 aa)
initn: 358 init1: 231 opt: 405 Z-score: 481.7 bits: 98.6 E(85289): 4.3e-20
Smith-Waterman score: 444; 26.7% identity (56.5% similar) in 430 aa overlap (128-523:14-420)
100 110 120 130 140 150
pF1KB5 SVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVD----HIRTIYHMFIALLILFI
: : :. : . : : . ...:::
XP_011 MGAELVGEAWCHRLQDSLFSSDSGFSNYRGILNWCVVMLILSN
10 20 30 40
160 170 180 190 200
pF1KB5 LSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTW----WIMFLSTFSVPYF-LFQHWAT
.. . : : :: ....: : : : ..: .. ..:.: : . .. :.
XP_011 ARLFLENLIKYGILVDPIQVVSL-FLKDP---YSWPAPCLVIAANVFAVAAFQVEKRLAV
50 60 70 80 90
210 220 230 240 250 260
pF1KB5 GYSKSSHPLIRSLFHGFLFMIFQIG-VLGFGPTYVVLAYTLPPASRFI------IIFEQI
: . :.:. . ... .: : . :.:. .. :.. .. :.: ..
XP_011 GALTEQA--------GLLLHVANLATILCFPAAVVLLVESITPVGSLLALMAHTILFLKL
100 110 120 130 140 150
270 280 290 300 310
pF1KB5 RFVMKAHSFVRENVPRVLNSAKEKSS-----TVPIP---TVNQYLYFLFAPTLIYRDSYP
..:. :. .. ...:. :: :: : : . :::::::: :. ..:
XP_011 FSYRDVNSWCRRARAKAASAGKKASSAAAPHTVSYPDNLTYRDLYYFLFAPTLCYELNFP
160 170 180 190 200 210
320 330 340 350 360
pF1KB5 RNPTVRWGYVAMKFAQVFGCFFYVYYI--FERLCAPLFRNIKQEPFS----ARVLVLCVF
:.: .: .. .. ... :: . ... .: ..: ...::. .:. . ..
XP_011 RSPRIRKRFLLRRILEML--FFTQLQVGLIQQWMVPTIQN-SMKPFKDMDYSRI-IERLL
220 230 240 250 260
370 380 390 400 410 420
pF1KB5 NSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDW
. .:. :: .. :. ..: ::: ::...:::: ::.::::: : . ....::. :: :
XP_011 KLAVPNHLIWLIFFYWLFHSCLNAVAELMQFGDREFYRDWWNSESVTYFWQNWNIPVHKW
270 280 290 300 310 320
430 440 450 460 470 480
pF1KB5 LYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMA--
. :: .: :... : .:: .:: ::: ..: : .: :. : ::
XP_011 CIRHFYKPMLRRGSSKW--MARTGVFLASAFFHEYLVSVPLR-----MFRLWAFTGMMAQ
330 340 350 360 370 380
490 500 510 520 530 540
pF1KB5 --FNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRS
. ..:. . :. .: ::..:. . . .: ...:
XP_011 IPLAWFVGRFFQGNYGNAAVWLSLIIGQPIAVLMYVHDYYVLNYEAPAAEA
390 400 410 420 430
550
pF1KB5 WTCRYVF
550 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:12:16 2016 done: Sat Nov 5 13:12:17 2016
Total Scan time: 9.110 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]