Result of FASTA (omim) for
pFN21AE4542
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4542, 626 aa
1>>>pF1KE4542 626 - 626 aa - 626 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.3819+/-0.000496; mu= -20.3645+/- 0.030
mean_var=468.2960+/-100.311, 0's: 0 Z-trim(120.3): 76 B-trim: 1597 in 1/60
Lambda= 0.059267
statistics sampled from 35234 (35320) to 35234 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.414), width: 16
Scan time: 12.920
The best scores are: opt bits E(85289)
NP_000164 (OMIM: 153670,177820,231200,258660,60667 ( 652) 2929 265.5 4.1e-70
NP_443204 (OMIM: 611289) leucine-rich alpha-2-glyc ( 347) 370 46.5 0.00018
NP_001073982 (OMIM: 603104) carboxypeptidase N sub ( 545) 341 44.2 0.0015
NP_001278917 (OMIM: 603104) carboxypeptidase N sub ( 545) 341 44.2 0.0015
XP_005269337 (OMIM: 603104) PREDICTED: carboxypept ( 545) 341 44.2 0.0015
NP_004479 (OMIM: 173511) platelet glycoprotein V p ( 560) 330 43.2 0.0029
>>NP_000164 (OMIM: 153670,177820,231200,258660,606672) p (652 aa)
initn: 2890 init1: 2890 opt: 2929 Z-score: 1379.7 bits: 265.5 E(85289): 4.1e-70
Smith-Waterman score: 4136; 95.9% identity (96.0% similar) in 652 aa overlap (1-626:1-652)
10 20 30 40 50 60
pF1KE4 MPLLLLLLLLPSPLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPLLLLLLLLPSPLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 AGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDLYDYYPEEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDLYDYYPEEDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 EGDKVRATRTVVKFPTKAHTTPWGLFYSWSTASLDSQMPSSLHPTQESTKEQTTFPPRWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGDKVRATRTVVKFPTKAHTTPWGLFYSWSTASLDSQMPSSLHPTQESTKEQTTFPPRWT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 PNFTLHMESITFSKTPKSTTEPTPSPTTSEPVPEPAPNMTTLEPTPSPTTPEPTSEPAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PNFTLHMESITFSKTPKSTTEPTPSPTTSEPVPEPAPNMTTLEPTPSPTTPEPTSEPAPS
370 380 390 400 410 420
430 440 450
pF1KE4 PTTPEPT--------------------------PIPTIATSPTILVSATSLITPKSTFLT
::::::: :::::::::::::::::::::::::::
NP_000 PTTPEPTSEPAPSPTTPEPTSEPAPSPTTPEPTPIPTIATSPTILVSATSLITPKSTFLT
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE4 TTKPVSLLESTKKTIPELDQPPKLRGVLQGHLESSRNDPFLHPDFCCLLPLGFYVLGLFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTKPVSLLESTKKTIPELDQPPKLRGVLQGHLESSRNDPFLHPDFCCLLPLGFYVLGLFW
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE4 LLFASVVLILLLSWVGHVKPQALDSGQGAALTTATQTTHLELQRGRQVTVPRAWLLFLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLFASVVLILLLSWVGHVKPQALDSGQGAALTTATQTTHLELQRGRQVTVPRAWLLFLRG
550 560 570 580 590 600
580 590 600 610 620
pF1KE4 SLPTFRSSLFLWVRPNGRLGPLVAGRRPSALSQGRGQDLLSTVSIRYSGHSL
::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_000 SLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLSTVSIRYSGHSL
610 620 630 640 650
>>NP_443204 (OMIM: 611289) leucine-rich alpha-2-glycopro (347 aa)
initn: 499 init1: 229 opt: 370 Z-score: 201.1 bits: 46.5 E(85289): 0.00018
Smith-Waterman score: 370; 34.8% identity (66.1% similar) in 233 aa overlap (26-244:91-322)
10 20 30 40 50
pF1KE4 MPLLLLLLLLPSPLHPHPICEVSKVASHL-EVNCDKRNLTALPPDLPKDTT---I
::.: :.. .. .: .: :.. . . .
NP_443 EIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRV
70 80 90 100 110 120
60 70 80 90 100
pF1KE4 LHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLP
: :..: : . . .. . : : : . .: :.:. : .:: :::: :.:..::
NP_443 LDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLP
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE4 --LLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLE
::.. . : .::.. :.: .:: ::: .:..:.:.::.:..: :: : : :.
NP_443 PGLLAN-FTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLR
190 200 210 220 230
170 180 190 200 210 220
pF1KE4 KLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPF-----AF-LHGN
: : .:.:... :: ..::..:: : :..::: ..:.:...: : .: . ::
NP_443 YLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGN
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE4 PWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCP
::.:. .. . :::: . ....
NP_443 PWICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAVKGQTLLAVAKSQ
300 310 320 330 340
>>NP_001073982 (OMIM: 603104) carboxypeptidase N subunit (545 aa)
initn: 586 init1: 227 opt: 341 Z-score: 184.9 bits: 44.2 E(85289): 0.0015
Smith-Waterman score: 341; 32.7% identity (61.7% similar) in 248 aa overlap (7-240:12-252)
10 20 30 40
pF1KE4 MPLLLLLLLLPSPLHPHPI---CEVSKVASHLEVNCDKRNLTALPPDLP---KDT
:::: : .: :. : :. :: :. ..:...: :.: :.
NP_001 MLPGAWLLWTSLLLLARPAQPCPMGCDCFVQ------EVFCSDEELATVPLDIPPYTKNI
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 TILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLP
... : . : : .... :... :: . :.. . .. : :: : :... ... .:
NP_001 IFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQF-RPDAFGGLPRLEDLEVTGSSFLNLS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 L-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEK
. ..: .: : ..:: : .:: : .. :. :. :.:.::.:..:: :. : .:.
NP_001 TNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 LSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGS-HLLPFAFLHGN------
:.::.: :..:: :.. : .:.:: :..:.: .:.: ::. : :: .:
NP_001 LNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 PWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCP
: . . . : ::: ::
NP_001 PQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVG
240 250 260 270 280 290
>>NP_001278917 (OMIM: 603104) carboxypeptidase N subunit (545 aa)
initn: 586 init1: 227 opt: 341 Z-score: 184.9 bits: 44.2 E(85289): 0.0015
Smith-Waterman score: 341; 32.7% identity (61.7% similar) in 248 aa overlap (7-240:12-252)
10 20 30 40
pF1KE4 MPLLLLLLLLPSPLHPHPI---CEVSKVASHLEVNCDKRNLTALPPDLP---KDT
:::: : .: :. : :. :: :. ..:...: :.: :.
NP_001 MLPGAWLLWTSLLLLARPAQPCPMGCDCFVQ------EVFCSDEELATVPLDIPPYTKNI
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 TILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLP
... : . : : .... :... :: . :.. . .. : :: : :... ... .:
NP_001 IFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQF-RPDAFGGLPRLEDLEVTGSSFLNLS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 L-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEK
. ..: .: : ..:: : .:: : .. :. :. :.:.::.:..:: :. : .:.
NP_001 TNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 LSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGS-HLLPFAFLHGN------
:.::.: :..:: :.. : .:.:: :..:.: .:.: ::. : :: .:
NP_001 LNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 PWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCP
: . . . : ::: ::
NP_001 PQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVG
240 250 260 270 280 290
>>XP_005269337 (OMIM: 603104) PREDICTED: carboxypeptidas (545 aa)
initn: 586 init1: 227 opt: 341 Z-score: 184.9 bits: 44.2 E(85289): 0.0015
Smith-Waterman score: 341; 32.7% identity (61.7% similar) in 248 aa overlap (7-240:12-252)
10 20 30 40
pF1KE4 MPLLLLLLLLPSPLHPHPI---CEVSKVASHLEVNCDKRNLTALPPDLP---KDT
:::: : .: :. : :. :: :. ..:...: :.: :.
XP_005 MLPGAWLLWTSLLLLARPAQPCPMGCDCFVQ------EVFCSDEELATVPLDIPPYTKNI
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 TILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLP
... : . : : .... :... :: . :.. . .. : :: : :... ... .:
XP_005 IFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQF-RPDAFGGLPRLEDLEVTGSSFLNLS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 L-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEK
. ..: .: : ..:: : .:: : .. :. :. :.:.::.:..:: :. : .:.
XP_005 TNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 LSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGS-HLLPFAFLHGN------
:.::.: :..:: :.. : .:.:: :..:.: .:.: ::. : :: .:
XP_005 LNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 PWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCP
: . . . : ::: ::
XP_005 PQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVG
240 250 260 270 280 290
>>NP_004479 (OMIM: 173511) platelet glycoprotein V precu (560 aa)
initn: 412 init1: 227 opt: 330 Z-score: 179.6 bits: 43.2 E(85289): 0.0029
Smith-Waterman score: 330; 34.4% identity (61.5% similar) in 218 aa overlap (30-239:222-439)
10 20 30 40 50
pF1KE4 MPLLLLLLLLPSPLHPHPICEVSKVASHLEVNCDKRNLTALPP---DLPKDTTILHLSE
:.. . .. .. : : . . : ::.
NP_004 AQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSR
200 210 220 230 240 250
60 70 80 90 100 110
pF1KE4 NLLYTFSLATLMPYTRLTQLNLDRCELTKLQ--VDGTLPVLGTLDLSHNQLQSLPLLG-Q
: : . : .. :: :.: . :..: . : . : : :...::..:: . .
NP_004 NHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFR
260 270 280 290 300 310
120 130 140 150 160 170
pF1KE4 TLPALTVLDVSFN-RLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLA
.: : : :... ::..:: ::..:::::: : :..: : .:: ::: ::...::
NP_004 NLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLR
320 330 340 350 360 370
180 190 200 210 220 230
pF1KE4 NNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGS-HLLPFAFLHGNPWLCNCEILY
: : :: .:. .: .:... :..:.: :.: ::. : ..: : : :.: .
NP_004 RNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLGP
380 390 400 410 420 430
240 250 260 270 280 290
pF1KE4 FRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPTLGDEGDTDL
: ::...
NP_004 FLGWLRQHLGLVGGEEPPRCAGPGAHAGLPLWALPGGDAECPGPRGPPPRPAADSSSEAP
440 450 460 470 480 490
626 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:07:10 2016 done: Sun Nov 6 00:07:12 2016
Total Scan time: 12.920 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]