Result of FASTA (omim) for
pFN21AB5326
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5326, 450 aa
1>>>pF1KB5326 450 - 450 aa - 450 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2480+/-0.000398; mu= 13.8227+/- 0.025
mean_var=97.8031+/-19.576, 0's: 0 Z-trim(114.9): 52 B-trim: 1014 in 2/54
Lambda= 0.129687
statistics sampled from 24905 (24957) to 24905 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.293), width: 16
Scan time: 9.100
The best scores are: opt bits E(85289)
NP_003785 (OMIM: 605931) sorting nexin-4 [Homo sap ( 450) 2981 568.2 1.5e-161
XP_016862903 (OMIM: 605931) PREDICTED: sorting nex ( 482) 1755 338.9 1.8e-92
XP_016856917 (OMIM: 614904) PREDICTED: sorting nex ( 336) 333 72.7 1.6e-12
XP_006710740 (OMIM: 614904) PREDICTED: sorting nex ( 422) 333 72.8 2e-12
XP_006710741 (OMIM: 614904) PREDICTED: sorting nex ( 387) 330 72.2 2.7e-12
XP_016856916 (OMIM: 614904) PREDICTED: sorting nex ( 387) 330 72.2 2.7e-12
XP_016856915 (OMIM: 614904) PREDICTED: sorting nex ( 387) 330 72.2 2.7e-12
XP_011539866 (OMIM: 614904) PREDICTED: sorting nex ( 387) 330 72.2 2.7e-12
XP_016856914 (OMIM: 614904) PREDICTED: sorting nex ( 387) 330 72.2 2.7e-12
NP_057060 (OMIM: 614904) sorting nexin-7 isoform a ( 451) 330 72.2 3.1e-12
NP_001265128 (OMIM: 605929) sorting nexin-2 isofor ( 402) 218 51.3 5.7e-06
NP_003091 (OMIM: 605929) sorting nexin-2 isoform 1 ( 519) 218 51.3 7e-06
NP_001287858 (OMIM: 605930) sorting nexin-3 isofor ( 140) 187 45.2 0.00014
NP_003786 (OMIM: 605930) sorting nexin-3 isoform a ( 162) 187 45.2 0.00015
NP_001243117 (OMIM: 300883) sorting nexin-12 isofo ( 158) 171 42.2 0.0012
NP_037478 (OMIM: 300883) sorting nexin-12 isoform ( 162) 171 42.2 0.0012
NP_001243114 (OMIM: 300883) sorting nexin-12 isofo ( 162) 171 42.2 0.0012
>>NP_003785 (OMIM: 605931) sorting nexin-4 [Homo sapiens (450 aa)
initn: 2981 init1: 2981 opt: 2981 Z-score: 3021.3 bits: 568.2 E(85289): 1.5e-161
Smith-Waterman score: 2981; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450)
10 20 30 40 50 60
pF1KB5 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE
370 380 390 400 410 420
430 440 450
pF1KB5 ALISYAVMQISMCKKGIQVWTNAKECFSKM
::::::::::::::::::::::::::::::
NP_003 ALISYAVMQISMCKKGIQVWTNAKECFSKM
430 440 450
>>XP_016862903 (OMIM: 605931) PREDICTED: sorting nexin-4 (482 aa)
initn: 2967 init1: 1748 opt: 1755 Z-score: 1781.2 bits: 338.9 E(85289): 1.8e-92
Smith-Waterman score: 2907; 93.4% identity (93.4% similar) in 482 aa overlap (1-450:1-482)
10 20 30 40 50 60
pF1KB5 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
190 200 210 220 230 240
250 260
pF1KB5 RARVADRLYGVYKVHGNYGRVF--------------------------------SEWSAI
:::::::::::::::::::::: ::::::
XP_016 RARVADRLYGVYKVHGNYGRVFRHSWSLFFFLISWSYKILERPLWFFSSSSRSKSEWSAI
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB5 EKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB5 EMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQ
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB5 LKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVWTNAKECFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVWTNAKECFS
430 440 450 460 470 480
450
pF1KB5 KM
::
XP_016 KM
>>XP_016856917 (OMIM: 614904) PREDICTED: sorting nexin-7 (336 aa)
initn: 241 init1: 113 opt: 333 Z-score: 345.6 bits: 72.7 E(85289): 1.6e-12
Smith-Waterman score: 342; 25.5% identity (60.2% similar) in 322 aa overlap (55-371:29-335)
30 40 50 60 70 80
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
:: . :.:.: :.. .. ::. .:
XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
: :.. . .: . . :::..: :.. : .: ...:::::: :. . . ..
XP_016 IITKTSRGEFDSSEFE--VRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
60 70 80 90 100
150 160 170 180 190 200
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
.. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. .
XP_016 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
. ..:. ...: ::: ..: ..... . ... :. . .. :. . . .::
XP_016 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
170 180 190 200 210 220
270 280 290 300 310
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
. ::: :... : :.... .: .. . . : ..::..:.: : .: .
XP_016 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
... .: .:. .. :. :: . . : .: ..: . :.: .:. :..
XP_016 RRDQIQAELDSKVEVLTYKKADTD-LCLATWESFLTS--QTNLHLEEASEDKP
290 300 310 320 330
380 390 400 410 420 430
pF1KB5 EQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQV
>>XP_006710740 (OMIM: 614904) PREDICTED: sorting nexin-7 (422 aa)
initn: 241 init1: 113 opt: 333 Z-score: 344.1 bits: 72.8 E(85289): 2e-12
Smith-Waterman score: 342; 25.5% identity (60.2% similar) in 322 aa overlap (55-371:115-421)
30 40 50 60 70 80
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
:: . :.:.: :.. .. ::. .:
XP_006 SLMDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
90 100 110 120 130
90 100 110 120 130 140
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
: :.. . .: . . :::..: :.. : .: ...:::::: :. . . ..
XP_006 IITKTSRGEFDSSEFE--VRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
.. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. .
XP_006 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
. ..:. ...: ::: ..: ..... . ... :. . .. :. . . .::
XP_006 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
260 270 280 290 300 310
270 280 290 300 310
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
. ::: :... : :.... .: .. . . : ..::..:.: : .: .
XP_006 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
320 330 340 350 360 370
320 330 340 350 360 370
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
... .: .:. .. :. :: . . : .: ..: . :.: .:. :..
XP_006 RRDQIQAELDSKVEVLTYKKADTD-LCLATWESFLTS--QTNLHLEEASEDKP
380 390 400 410 420
380 390 400 410 420 430
pF1KB5 EQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQV
>>XP_006710741 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 279 init1: 113 opt: 330 Z-score: 341.6 bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)
30 40 50 60 70 80
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
:: . :.:.: :.. .. ::. .:
XP_006 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
: :.. . .: . . :::..: :.. : .: ...:::::: :. . . ..
XP_006 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
60 70 80 90 100
150 160 170 180 190 200
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
.. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. .
XP_006 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
. ..:. ...: ::: ..: ..... . ... :. . .. :. . . .::
XP_006 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
170 180 190 200 210 220
270 280 290 300 310
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
. ::: :... : :.... .: .. . . : ..::..:.: : .: .
XP_006 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
... .: .:. .. :. :: . . :
XP_006 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
290 300 310 320 330 340
>>XP_016856916 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 279 init1: 113 opt: 330 Z-score: 341.6 bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)
30 40 50 60 70 80
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
:: . :.:.: :.. .. ::. .:
XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
: :.. . .: . . :::..: :.. : .: ...:::::: :. . . ..
XP_016 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
60 70 80 90 100
150 160 170 180 190 200
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
.. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. .
XP_016 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
. ..:. ...: ::: ..: ..... . ... :. . .. :. . . .::
XP_016 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
170 180 190 200 210 220
270 280 290 300 310
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
. ::: :... : :.... .: .. . . : ..::..:.: : .: .
XP_016 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
... .: .:. .. :. :: . . :
XP_016 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
290 300 310 320 330 340
>>XP_016856915 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 279 init1: 113 opt: 330 Z-score: 341.6 bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)
30 40 50 60 70 80
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
:: . :.:.: :.. .. ::. .:
XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
: :.. . .: . . :::..: :.. : .: ...:::::: :. . . ..
XP_016 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
60 70 80 90 100
150 160 170 180 190 200
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
.. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. .
XP_016 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
. ..:. ...: ::: ..: ..... . ... :. . .. :. . . .::
XP_016 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
170 180 190 200 210 220
270 280 290 300 310
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
. ::: :... : :.... .: .. . . : ..::..:.: : .: .
XP_016 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
... .: .:. .. :. :: . . :
XP_016 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
290 300 310 320 330 340
>>XP_011539866 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 279 init1: 113 opt: 330 Z-score: 341.6 bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)
30 40 50 60 70 80
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
:: . :.:.: :.. .. ::. .:
XP_011 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
: :.. . .: . . :::..: :.. : .: ...:::::: :. . . ..
XP_011 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
60 70 80 90 100
150 160 170 180 190 200
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
.. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. .
XP_011 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
. ..:. ...: ::: ..: ..... . ... :. . .. :. . . .::
XP_011 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
170 180 190 200 210 220
270 280 290 300 310
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
. ::: :... : :.... .: .. . . : ..::..:.: : .: .
XP_011 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
... .: .:. .. :. :: . . :
XP_011 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
290 300 310 320 330 340
>>XP_016856914 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 279 init1: 113 opt: 330 Z-score: 341.6 bits: 72.2 E(85289): 2.7e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:29-312)
30 40 50 60 70 80
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
:: . :.:.: :.. .. ::. .:
XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
: :.. . .: . . :::..: :.. : .: ...:::::: :. . . ..
XP_016 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
60 70 80 90 100
150 160 170 180 190 200
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
.. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. .
XP_016 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
. ..:. ...: ::: ..: ..... . ... :. . .. :. . . .::
XP_016 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
170 180 190 200 210 220
270 280 290 300 310
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
. ::: :... : :.... .: .. . . : ..::..:.: : .: .
XP_016 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
... .: .:. .. :. :: . . :
XP_016 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
290 300 310 320 330 340
>>NP_057060 (OMIM: 614904) sorting nexin-7 isoform a [Ho (451 aa)
initn: 241 init1: 113 opt: 330 Z-score: 340.7 bits: 72.2 E(85289): 3.1e-12
Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (55-345:93-376)
30 40 50 60 70 80
pF1KB5 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL
:: . :.:.: :.. .. ::. .:
NP_057 SLMDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR
70 80 90 100 110
90 100 110 120 130 140
pF1KB5 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD
: :.. . .: . . :::..: :.. : .: ...:::::: :. . . ..
NP_057 IITKTSRGEFDSSEF--EVRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB5 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD
.. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. .
NP_057 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB5 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR
. ..:. ...: ::: ..: ..... . ... :. . .. :. . . .::
NP_057 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP
240 250 260 270 280 290
270 280 290 300 310
pF1KB5 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR
. ::: :... : :.... .: .. . . : ..::..:.: : .: .
NP_057 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB5 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE
... .: .:. .. :. :: . . :
NP_057 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK
360 370 380 390 400 410
450 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:28:23 2016 done: Sat Nov 5 12:28:24 2016
Total Scan time: 9.100 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]