Result of FASTA (omim) for
pFN21AB5364
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5364, 395 aa
1>>>pF1KB5364 395 - 395 aa - 395 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7340+/-0.000375; mu= 20.2742+/- 0.023
mean_var=64.9988+/-13.297, 0's: 0 Z-trim(112.9): 20 B-trim: 0 in 0/52
Lambda= 0.159082
statistics sampled from 21936 (21954) to 21936 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.257), width: 16
Scan time: 8.240
The best scores are: opt bits E(85289)
NP_808592 (OMIM: 159950,228000,613468) acid cerami ( 395) 2682 624.4 1.4e-178
XP_005273561 (OMIM: 159950,228000,613468) PREDICTE ( 373) 2507 584.2 1.7e-166
NP_004306 (OMIM: 159950,228000,613468) acid cerami ( 411) 2507 584.3 1.8e-166
NP_001120977 (OMIM: 159950,228000,613468) acid cer ( 389) 1987 464.9 1.5e-130
XP_005262977 (OMIM: 607469) PREDICTED: N-acylethan ( 359) 460 114.4 4.3e-25
XP_016863517 (OMIM: 607469) PREDICTED: N-acylethan ( 359) 460 114.4 4.3e-25
NP_055250 (OMIM: 607469) N-acylethanolamine-hydrol ( 359) 460 114.4 4.3e-25
XP_016863516 (OMIM: 607469) PREDICTED: N-acylethan ( 366) 460 114.4 4.4e-25
XP_011530154 (OMIM: 607469) PREDICTED: N-acylethan ( 347) 433 108.2 3.1e-23
XP_005262980 (OMIM: 607469) PREDICTED: N-acylethan ( 333) 428 107.1 6.6e-23
XP_005262978 (OMIM: 607469) PREDICTED: N-acylethan ( 336) 423 105.9 1.5e-22
XP_006714243 (OMIM: 607469) PREDICTED: N-acylethan ( 340) 422 105.7 1.7e-22
XP_016863518 (OMIM: 607469) PREDICTED: N-acylethan ( 357) 422 105.7 1.8e-22
XP_005262981 (OMIM: 607469) PREDICTED: N-acylethan ( 326) 393 99.0 1.7e-20
XP_016863519 (OMIM: 607469) PREDICTED: N-acylethan ( 334) 391 98.6 2.4e-20
XP_005262982 (OMIM: 607469) PREDICTED: N-acylethan ( 323) 390 98.3 2.7e-20
NP_001035861 (OMIM: 607469) N-acylethanolamine-hyd ( 323) 390 98.3 2.7e-20
XP_011530156 (OMIM: 607469) PREDICTED: N-acylethan ( 325) 390 98.3 2.7e-20
>>NP_808592 (OMIM: 159950,228000,613468) acid ceramidase (395 aa)
initn: 2682 init1: 2682 opt: 2682 Z-score: 3327.0 bits: 624.4 E(85289): 1.4e-178
Smith-Waterman score: 2682; 99.2% identity (100.0% similar) in 395 aa overlap (1-395:1-395)
10 20 30 40 50 60
pF1KB5 MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RWHELMLDKAPMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIA
:::::::::::.::::::::::::::::::::.:::::::::::::::::::::::::::
NP_808 RWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 AVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 QLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 QLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LGKKDAMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKE
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 LGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_808 SLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLST
310 320 330 340 350 360
370 380 390
pF1KB5 KPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
:::::::::::::::::::::::::::::::::::
NP_808 KPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
370 380 390
>>XP_005273561 (OMIM: 159950,228000,613468) PREDICTED: a (373 aa)
initn: 2507 init1: 2507 opt: 2507 Z-score: 3110.2 bits: 584.2 E(85289): 1.7e-166
Smith-Waterman score: 2507; 99.2% identity (100.0% similar) in 369 aa overlap (27-395:5-373)
10 20 30 40 50 60
pF1KB5 MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYK
::::::::::::::::::::::::::::::::::
XP_005 MEAQWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYK
10 20 30
70 80 90 100 110 120
pF1KB5 RWHELMLDKAPMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIA
:::::::::::.::::::::::::::::::::.:::::::::::::::::::::::::::
XP_005 RWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 AVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 QLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWI
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LGKKDAMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKE
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 SLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLST
280 290 300 310 320 330
370 380 390
pF1KB5 KPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
:::::::::::::::::::::::::::::::::::
XP_005 KPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
340 350 360 370
>>NP_004306 (OMIM: 159950,228000,613468) acid ceramidase (411 aa)
initn: 2507 init1: 2507 opt: 2507 Z-score: 3109.7 bits: 584.3 E(85289): 1.8e-166
Smith-Waterman score: 2507; 99.2% identity (100.0% similar) in 369 aa overlap (27-395:43-411)
10 20 30 40 50
pF1KB5 MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDL
::::::::::::::::::::::::::::::
NP_004 GSHRASYPSLSALFTEASILGFGSFAVKAQWTEDCRKSTYPPSGPTYRGAVPWYTINLDL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB5 PPYKRWHELMLDKAPMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEM
:::::::::::::::.::::::::::::::::::::.:::::::::::::::::::::::
NP_004 PPYKRWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEM
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB5 KGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTW
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB5 VITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGI
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB5 LEWILGKKDAMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITR
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITR
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB5 DRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYD
320 330 340 350 360 370
360 370 380 390
pF1KB5 VLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
:::::::::::::::::::::::::::::::::::::::
NP_004 VLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
380 390 400 410
>>NP_001120977 (OMIM: 159950,228000,613468) acid ceramid (389 aa)
initn: 2311 init1: 1987 opt: 1987 Z-score: 2465.0 bits: 464.9 E(85289): 1.5e-130
Smith-Waterman score: 2240; 89.9% identity (90.4% similar) in 376 aa overlap (27-395:43-389)
10 20 30 40
pF1KB5 MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPT-------YRGAVPW
:::::::::::::::: :::::::
NP_001 GSHRASYPSLSALFTEASILGFGSFAVKAQWTEDCRKSTYPPSGPTVFPAVIRYRGAVPW
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB5 YTINLDLPPYKRWHELMLDKAPMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFP
::::::::::::::::::::::. ::::::::
NP_001 YTINLDLPPYKRWHELMLDKAPV-----------------------------PGLLGNFP
80 90 100
110 120 130 140 150 160
pF1KB5 GPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGW
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB5 NINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSI
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 NGGYLGILEWILGKKDAMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSG
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 NGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSG
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB5 EGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENI
290 300 310 320 330 340
350 360 370 380 390
pF1KB5 SFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
350 360 370 380
>>XP_005262977 (OMIM: 607469) PREDICTED: N-acylethanolam (359 aa)
initn: 648 init1: 316 opt: 460 Z-score: 571.5 bits: 114.4 E(85289): 4.3e-25
Smith-Waterman score: 642; 33.9% identity (64.1% similar) in 354 aa overlap (46-387:32-355)
20 30 40 50 60
pF1KB5 VSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRW------HELMLDK
:.: ....:: : :: ..: : .
XP_005 RTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 APMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGE
: : .:: . . . ..... :::. ... : : :: :..:. .. :..
XP_005 AAMAQVIGDRVPKWVHVLI--GKVVLELERFL-------PQPFTGEIRGMCDFMNLSLAD
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNL
. :. :: ..::::::.:..::. ::::.:. .: :. :. :::..
XP_005 CLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYP--FG-NV----------LRKLTVDV
120 130 140 150
190 200 210 220 230 240
pF1KB5 DFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDAMW-
.: .:.. .: ...: ::::. :: .: :... .:: . :. : . :..
XP_005 QFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDER---DKGW-----WWENAIAALFR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 ----IGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDV
...: :..: .: ..: : . :.:: ..: .:.:.::.. :: ::::.: :.
XP_005 RHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADI
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 YELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVL
. :: .: :. :.::::.:: ::::: : :: :.: :.:.:.....::. ::
XP_005 WPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVY
280 290 300 310 320 330
370 380 390
pF1KB5 NKLTVYTTLIDV-TKGQFETYLRDCPDPCIGW
:..:.:::.... . .. : .:.
XP_005 NNFTIYTTVMSAGSPDKYMTRIRNPSRK
340 350
>>XP_016863517 (OMIM: 607469) PREDICTED: N-acylethanolam (359 aa)
initn: 648 init1: 316 opt: 460 Z-score: 571.5 bits: 114.4 E(85289): 4.3e-25
Smith-Waterman score: 642; 33.9% identity (64.1% similar) in 354 aa overlap (46-387:32-355)
20 30 40 50 60
pF1KB5 VSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRW------HELMLDK
:.: ....:: : :: ..: : .
XP_016 RTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 APMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGE
: : .:: . . . ..... :::. ... : : :: :..:. .. :..
XP_016 AAMAQVIGDRVPKWVHVLI--GKVVLELERFL-------PQPFTGEIRGMCDFMNLSLAD
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNL
. :. :: ..::::::.:..::. ::::.:. .: :. :. :::..
XP_016 CLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYP--FG-NV----------LRKLTVDV
120 130 140 150
190 200 210 220 230 240
pF1KB5 DFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDAMW-
.: .:.. .: ...: ::::. :: .: :... .:: . :. : . :..
XP_016 QFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDER---DKGW-----WWENAIAALFR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 ----IGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDV
...: :..: .: ..: : . :.:: ..: .:.:.::.. :: ::::.: :.
XP_016 RHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADI
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 YELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVL
. :: .: :. :.::::.:: ::::: : :: :.: :.:.:.....::. ::
XP_016 WPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVY
280 290 300 310 320 330
370 380 390
pF1KB5 NKLTVYTTLIDV-TKGQFETYLRDCPDPCIGW
:..:.:::.... . .. : .:.
XP_016 NNFTIYTTVMSAGSPDKYMTRIRNPSRK
340 350
>>NP_055250 (OMIM: 607469) N-acylethanolamine-hydrolyzin (359 aa)
initn: 648 init1: 316 opt: 460 Z-score: 571.5 bits: 114.4 E(85289): 4.3e-25
Smith-Waterman score: 642; 33.9% identity (64.1% similar) in 354 aa overlap (46-387:32-355)
20 30 40 50 60
pF1KB5 VSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRW------HELMLDK
:.: ....:: : :: ..: : .
NP_055 RTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 APMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGE
: : .:: . . . ..... :::. ... : : :: :..:. .. :..
NP_055 AAMAQVIGDRVPKWVHVLI--GKVVLELERFL-------PQPFTGEIRGMCDFMNLSLAD
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNL
. :. :: ..::::::.:..::. ::::.:. .: :. :. :::..
NP_055 CLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYP--FG-NV----------LRKLTVDV
120 130 140 150
190 200 210 220 230 240
pF1KB5 DFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDAMW-
.: .:.. .: ...: ::::. :: .: :... .:: . :. : . :..
NP_055 QFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDER---DKGW-----WWENAIAALFR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 ----IGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDV
...: :..: .: ..: : . :.:: ..: .:.:.::.. :: ::::.: :.
NP_055 RHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADI
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 YELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVL
. :: .: :. :.::::.:: ::::: : :: :.: :.:.:.....::. ::
NP_055 WPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVY
280 290 300 310 320 330
370 380 390
pF1KB5 NKLTVYTTLIDV-TKGQFETYLRDCPDPCIGW
:..:.:::.... . .. : .:.
NP_055 NNFTIYTTVMSAGSPDKYMTRIRNPSRK
340 350
>>XP_016863516 (OMIM: 607469) PREDICTED: N-acylethanolam (366 aa)
initn: 648 init1: 316 opt: 460 Z-score: 571.3 bits: 114.4 E(85289): 4.4e-25
Smith-Waterman score: 642; 33.9% identity (64.1% similar) in 354 aa overlap (46-387:32-355)
20 30 40 50 60
pF1KB5 VSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRW------HELMLDK
:.: ....:: : :: ..: : .
XP_016 RTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 APMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGE
: : .:: . . . ..... :::. ... : : :: :..:. .. :..
XP_016 AAMAQVIGDRVPKWVHVLI--GKVVLELERFL-------PQPFTGEIRGMCDFMNLSLAD
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNL
. :. :: ..::::::.:..::. ::::.:. .: :. :. :::..
XP_016 CLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYP--FG-NV----------LRKLTVDV
120 130 140 150
190 200 210 220 230 240
pF1KB5 DFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDAMW-
.: .:.. .: ...: ::::. :: .: :... .:: . :. : . :..
XP_016 QFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDER---DKGW-----WWENAIAALFR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 ----IGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDV
...: :..: .: ..: : . :.:: ..: .:.:.::.. :: ::::.: :.
XP_016 RHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADI
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 YELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVL
. :: .: :. :.::::.:: ::::: : :: :.: :.:.:.....::. ::
XP_016 WPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVY
280 290 300 310 320 330
370 380 390
pF1KB5 NKLTVYTTLIDV-TKGQFETYLRDCPDPCIGW
:..:.:::.... . .. : .:.
XP_016 NNFTIYTTVMSAGSPDKYMTRIRNPSRNEQEEPIR
340 350 360
>>XP_011530154 (OMIM: 607469) PREDICTED: N-acylethanolam (347 aa)
initn: 633 init1: 301 opt: 433 Z-score: 538.2 bits: 108.2 E(85289): 3.1e-23
Smith-Waterman score: 615; 34.8% identity (63.4% similar) in 333 aa overlap (46-367:32-334)
20 30 40 50 60
pF1KB5 VSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRW------HELMLDK
:.: ....:: : :: ..: : .
XP_011 RTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 APMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGE
: : .:: . . . ..... :::. ... :: :: :..:. .. :..
XP_011 AAMAQVIGDRVPKWVHVLI--GKVVLELERFLPQ-------PFTGEIRGMCDFMNLSLAD
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNL
. :. :: ..::::::.:..::. ::::.:. .: :. :. :::..
XP_011 CLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYP--FG-NV----------LRKLTVDV
120 130 140 150
190 200 210 220 230 240
pF1KB5 DFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDAMW-
.: .:.. .: ...: ::::. :: .: :... .:: . :. : . :..
XP_011 QFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDER---DKGW-----WWENAIAALFR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 ----IGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDV
...: :..: .: ..: : . :.:: ..: .:.:.::.. :: ::::.: :.
XP_011 RHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADI
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 YELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVL
. :: .: :. :.::::.:: ::::: : :: :.: :.:.:.....::. ::
XP_011 WPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVY
280 290 300 310 320 330
370 380 390
pF1KB5 NKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
:::
XP_011 NKLFPLAEFPEVGLLS
340
>>XP_005262980 (OMIM: 607469) PREDICTED: N-acylethanolam (333 aa)
initn: 628 init1: 296 opt: 428 Z-score: 532.2 bits: 107.1 E(85289): 6.6e-23
Smith-Waterman score: 610; 34.6% identity (63.3% similar) in 332 aa overlap (46-366:32-333)
20 30 40 50 60
pF1KB5 VSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRW------HELMLDK
:.: ....:: : :: ..: : .
XP_005 RTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 APMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGE
: : .:: . . . ..... :::. ... :: :: :..:. .. :..
XP_005 AAMAQVIGDRVPKWVHVLI--GKVVLELERFLPQ-------PFTGEIRGMCDFMNLSLAD
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 IISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNL
. :. :: ..::::::.:..::. ::::.:. .: :. :. :::..
XP_005 CLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYP--FG-NV----------LRKLTVDV
120 130 140 150
190 200 210 220 230 240
pF1KB5 DFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDAMW-
.: .:.. .: ...: ::::. :: .: :... .:: . :. : . :..
XP_005 QFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDER---DKGW-----WWENAIAALFR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 ----IGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDV
...: :..: .: ..: : . :.:: ..: .:.:.::.. :: ::::.: :.
XP_005 RHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADI
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 YELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVL
. :: .: :. :.::::.:: ::::: : :: :.: :.:.:.....::. ::
XP_005 WPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVY
280 290 300 310 320 330
370 380 390
pF1KB5 NKLTVYTTLIDVTKGQFETYLRDCPDPCIGW
::
XP_005 NK
395 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:31:12 2016 done: Sat Nov 5 12:31:13 2016
Total Scan time: 8.240 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]