Result of FASTA (omim) for
pFN21AE1528
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1528, 152 aa
1>>>pF1KE1528 152 - 152 aa - 152 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3408+/-0.000272; mu= 11.9874+/- 0.017
mean_var=66.9391+/-13.626, 0's: 0 Z-trim(119.7): 129 B-trim: 636 in 1/56
Lambda= 0.156760
statistics sampled from 33860 (33996) to 33860 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.399), width: 16
Scan time: 5.480
The best scores are: opt bits E(85289)
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 1033 241.5 4e-64
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 993 232.4 2.1e-61
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 775 183.1 1.2e-46
NP_861427 (OMIM: 300860,312180) ubiquitin-conjugat ( 122) 464 112.8 1.8e-25
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 440 107.4 9e-24
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 434 106.0 2.3e-23
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 432 105.6 3.2e-23
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 432 105.6 3.2e-23
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 432 105.6 3.2e-23
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 432 105.6 3.2e-23
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 432 105.6 3.2e-23
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 432 105.6 3.2e-23
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 432 105.6 3.2e-23
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 431 105.3 3.7e-23
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 429 104.9 5.1e-23
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 423 103.5 1.3e-22
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 422 103.3 1.6e-22
NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 422 103.3 1.6e-22
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 422 103.3 1.6e-22
XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 422 103.3 1.6e-22
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 422 103.3 1.6e-22
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 418 102.4 3.3e-22
NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 411 100.9 1e-21
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 399 98.1 6e-21
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 396 97.5 1.2e-20
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 396 97.5 1.2e-20
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 395 97.3 1.3e-20
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 394 97.1 1.6e-20
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 394 97.1 1.6e-20
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 394 97.1 1.6e-20
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 394 97.1 1.6e-20
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 394 97.1 1.6e-20
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 391 96.3 1.9e-20
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 374 92.4 2.3e-19
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 373 92.2 2.7e-19
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 373 92.2 2.7e-19
NP_055316 (OMIM: 610309) ubiquitin-conjugating enz ( 222) 376 93.0 2.9e-19
XP_011520946 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 374 92.5 3.4e-19
XP_011520947 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 374 92.5 3.4e-19
XP_005255597 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 374 92.5 3.4e-19
XP_005255598 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 374 92.5 3.4e-19
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 373 92.3 3.7e-19
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 363 90.0 1.9e-18
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 363 90.0 2e-18
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 353 87.7 8.8e-18
NP_003335 (OMIM: 601082) ubiquitin-conjugating enz ( 183) 348 86.6 2e-17
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 343 85.4 2.8e-17
NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 327 81.8 3.5e-16
NP_861516 (OMIM: 605574) ubiquitin-conjugating enz ( 150) 324 81.1 7.3e-16
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 316 79.4 2.8e-15
>>NP_003328 (OMIM: 179095) ubiquitin-conjugating enzyme (152 aa)
initn: 1033 init1: 1033 opt: 1033 Z-score: 1272.3 bits: 241.5 E(85289): 4e-64
Smith-Waterman score: 1033; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
70 80 90 100 110 120
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
::::::::::::::::::::::::::::::::
NP_003 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
130 140 150
>>NP_003327 (OMIM: 300860,312180) ubiquitin-conjugating (152 aa)
initn: 1006 init1: 993 opt: 993 Z-score: 1223.4 bits: 232.4 E(85289): 2.1e-61
Smith-Waterman score: 993; 96.0% identity (98.7% similar) in 151 aa overlap (1-151:1-151)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
:::::::::::::::::::::.:::::::::::: ::::::::::::::::::::.:::.
NP_003 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
70 80 90 100 110 120
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
::::::::::::::::::::::::::::: :
NP_003 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
130 140 150
>>NP_001269090 (OMIM: 300860,312180) ubiquitin-conjugati (119 aa)
initn: 784 init1: 771 opt: 775 Z-score: 958.6 bits: 183.1 E(85289): 1.2e-46
Smith-Waterman score: 775; 95.8% identity (98.3% similar) in 118 aa overlap (34-151:1-118)
10 20 30 40 50 60
pF1KE1 PARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEY
: ::::::::::::::::::::.:::.:::
NP_001 MVWNAVIFGPEGTPFEDGTFKLTIEFTEEY
10 20 30
70 80 90 100 110 120
pF1KE1 PNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPAN
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPAN
40 50 60 70 80 90
130 140 150
pF1KE1 SQAAQLYQENKREYEKRVSAIVEQSWNDS
:::::::::::::::::::::::::: :
NP_001 SQAAQLYQENKREYEKRVSAIVEQSWRDC
100 110
>>NP_861427 (OMIM: 300860,312180) ubiquitin-conjugating (122 aa)
initn: 784 init1: 462 opt: 464 Z-score: 578.3 bits: 112.8 E(85289): 1.8e-25
Smith-Waterman score: 728; 78.1% identity (78.8% similar) in 151 aa overlap (1-151:1-121)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
:::::::::::::::::::::.:::::::::::: :::::::::::::::
NP_861 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFED----------
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
::::::::::::::::::::::::::::::::::::::::
NP_861 --------------------VYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
60 70 80 90
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
::::::::::::::::::::::::::::: :
NP_861 PANSQAAQLYQENKREYEKRVSAIVEQSWRDC
100 110 120
>>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme (147 aa)
initn: 438 init1: 422 opt: 440 Z-score: 547.7 bits: 107.4 E(85289): 9e-24
Smith-Waterman score: 440; 41.5% identity (79.3% similar) in 135 aa overlap (5-139:2-136)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
: .:...... ::.:::. :..: .....:.:.:.:: . .. :.: :...:
NP_003 MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: . : .:..:::. ..::::::::...:::. ::..: :: ::: .:::..
NP_003 TDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
: . ::.:. .:..:..
NP_003 PLVPDIAQIYKSDKEKYNRHAREWTQKYAM
120 130 140
>>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa)
initn: 396 init1: 384 opt: 434 Z-score: 540.4 bits: 106.0 E(85289): 2.3e-23
Smith-Waterman score: 434; 40.0% identity (79.3% similar) in 135 aa overlap (5-139:2-136)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
: .:. .... : .:::. :..: .....:.:.:.::. .:.. :.: :.:.:
NP_003 MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : : ....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_003 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
: . :..:. ....:..
NP_003 PLVPEIARIYKTDREKYNRIAREWTQKYAM
120 130 140
>>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 396 init1: 384 opt: 432 Z-score: 538.0 bits: 105.6 E(85289): 3.2e-23
Smith-Waterman score: 432; 40.6% identity (78.3% similar) in 138 aa overlap (5-142:2-138)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
: .:. .... : .:::. :..: .....:.:.:.::. .:.. :.: :.:.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : : ....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_871 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
: . :..:. .. .:. :.:
NP_871 PLVPEIARIYKTDRDKYN-RISREWTQKYAM
120 130 140
>>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 396 init1: 384 opt: 432 Z-score: 538.0 bits: 105.6 E(85289): 3.2e-23
Smith-Waterman score: 432; 40.6% identity (78.3% similar) in 138 aa overlap (5-142:2-138)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
: .:. .... : .:::. :..: .....:.:.:.::. .:.. :.: :.:.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : : ....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_871 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
: . :..:. .. .:. :.:
NP_871 PLVPEIARIYKTDRDKYN-RISREWTQKYAM
120 130 140
>>NP_871620 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 396 init1: 384 opt: 432 Z-score: 538.0 bits: 105.6 E(85289): 3.2e-23
Smith-Waterman score: 432; 40.6% identity (78.3% similar) in 138 aa overlap (5-142:2-138)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
: .:. .... : .:::. :..: .....:.:.:.::. .:.. :.: :.:.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : : ....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_871 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
: . :..:. .. .:. :.:
NP_871 PLVPEIARIYKTDRDKYN-RISREWTQKYAM
120 130 140
>>NP_871616 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 396 init1: 384 opt: 432 Z-score: 538.0 bits: 105.6 E(85289): 3.2e-23
Smith-Waterman score: 432; 40.6% identity (78.3% similar) in 138 aa overlap (5-142:2-138)
10 20 30 40 50 60
pF1KE1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFS
: .:. .... : .:::. :..: .....:.:.:.::. .:.. :.: :.:.:
NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFP
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNS
.:: ::: : : ....:::. ..::::::::...:::. .:..: :: ::: .:::..
NP_871 TDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
130 140 150
pF1KE1 PANSQAAQLYQENKREYEKRVSAIVEQSWNDS
: . :..:. .. .:. :.:
NP_871 PLVPEIARIYKTDRDKYN-RISREWTQKYAM
120 130 140
152 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:18:27 2016 done: Mon Nov 7 02:18:28 2016
Total Scan time: 5.480 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]