Result of FASTA (ccds) for
pFN21AE1329
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1329, 597 aa
1>>>pF1KE1329 597 - 597 aa - 597 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8017+/-0.00107; mu= 17.1297+/- 0.065
mean_var=119.1696+/-24.011, 0's: 0 Z-trim(106.8): 173 B-trim: 0 in 0/50
Lambda= 0.117487
statistics sampled from 9016 (9216) to 9016 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.283), width: 16
Scan time: 3.310
The best scores are: opt bits E(32554)
CCDS41744.1 PTPN6 gene_id:5777|Hs108|chr12 ( 597) 4013 692.1 5.2e-199
CCDS44820.1 PTPN6 gene_id:5777|Hs108|chr12 ( 595) 3981 686.7 2.2e-197
CCDS44821.1 PTPN6 gene_id:5777|Hs108|chr12 ( 624) 3748 647.2 1.8e-185
CCDS9163.1 PTPN11 gene_id:5781|Hs108|chr12 ( 593) 2205 385.6 9.3e-107
CCDS81741.1 PTPN11 gene_id:5781|Hs108|chr12 ( 597) 2188 382.8 6.9e-106
CCDS58280.1 PTPN11 gene_id:5781|Hs108|chr12 ( 460) 1833 322.5 7.5e-88
CCDS47473.1 PTPRK gene_id:5796|Hs108|chr6 (1446) 700 131.0 1.1e-29
CCDS78179.1 PTPRK gene_id:5796|Hs108|chr6 (1462) 700 131.0 1.1e-29
CCDS7658.1 PTPRE gene_id:5791|Hs108|chr10 ( 642) 684 127.9 4e-29
CCDS7657.1 PTPRE gene_id:5791|Hs108|chr10 ( 700) 684 127.9 4.2e-29
CCDS75517.1 PTPRK gene_id:5796|Hs108|chr6 (1439) 679 127.4 1.2e-28
CCDS5137.1 PTPRK gene_id:5796|Hs108|chr6 (1440) 679 127.4 1.2e-28
CCDS42874.1 PTPRT gene_id:11122|Hs108|chr20 (1441) 669 125.7 4e-28
CCDS68127.1 PTPRT gene_id:11122|Hs108|chr20 (1460) 669 125.7 4.1e-28
CCDS5592.1 PTPN12 gene_id:5782|Hs108|chr7 ( 780) 665 124.7 4.2e-28
CCDS13039.1 PTPRA gene_id:5786|Hs108|chr20 ( 793) 660 123.9 7.7e-28
CCDS13038.1 PTPRA gene_id:5786|Hs108|chr20 ( 802) 660 123.9 7.8e-28
CCDS863.1 PTPN22 gene_id:26191|Hs108|chr1 ( 807) 657 123.4 1.1e-27
CCDS34740.1 PTPRZ1 gene_id:5803|Hs108|chr7 (2315) 659 124.2 1.8e-27
CCDS56505.1 PTPRZ1 gene_id:5803|Hs108|chr7 (1448) 654 123.2 2.4e-27
CCDS75813.1 PTPRD gene_id:5789|Hs108|chr9 (1496) 652 122.8 3e-27
CCDS55288.1 PTPRD gene_id:5789|Hs108|chr9 (1502) 652 122.8 3.1e-27
CCDS6472.2 PTPRD gene_id:5789|Hs108|chr9 (1505) 652 122.8 3.1e-27
CCDS55289.1 PTPRD gene_id:5789|Hs108|chr9 (1505) 652 122.8 3.1e-27
CCDS55290.1 PTPRD gene_id:5789|Hs108|chr9 (1506) 652 122.8 3.1e-27
CCDS43786.1 PTPRD gene_id:5789|Hs108|chr9 (1912) 652 123.0 3.6e-27
CCDS12139.1 PTPRS gene_id:5802|Hs108|chr19 (1501) 648 122.2 4.9e-27
CCDS74265.1 PTPRS gene_id:5802|Hs108|chr19 (1505) 648 122.2 4.9e-27
CCDS55846.1 PTPRB gene_id:5787|Hs108|chr12 (1907) 649 122.4 5.1e-27
CCDS55845.1 PTPRB gene_id:5787|Hs108|chr12 (1907) 649 122.4 5.1e-27
CCDS44944.1 PTPRB gene_id:5787|Hs108|chr12 (1997) 649 122.5 5.3e-27
CCDS81713.1 PTPRB gene_id:5787|Hs108|chr12 (2127) 649 122.5 5.5e-27
CCDS44943.1 PTPRB gene_id:5787|Hs108|chr12 (2215) 649 122.5 5.7e-27
CCDS12140.1 PTPRS gene_id:5802|Hs108|chr19 (1910) 648 122.3 5.8e-27
CCDS45930.1 PTPRS gene_id:5802|Hs108|chr19 (1948) 648 122.3 5.8e-27
CCDS11840.1 PTPRM gene_id:5797|Hs108|chr18 (1452) 641 121.0 1.1e-26
CCDS58613.1 PTPRM gene_id:5797|Hs108|chr18 (1465) 641 121.0 1.1e-26
CCDS1398.2 PTPRC gene_id:5788|Hs108|chr1 (1145) 633 119.5 2.4e-26
CCDS1397.2 PTPRC gene_id:5788|Hs108|chr1 (1306) 633 119.6 2.6e-26
CCDS53754.1 PTPRO gene_id:5800|Hs108|chr12 ( 377) 625 117.6 2.8e-26
CCDS44837.1 PTPRO gene_id:5800|Hs108|chr12 ( 405) 625 117.7 3e-26
CCDS54321.1 PTPRH gene_id:5794|Hs108|chr19 ( 937) 626 118.2 4.7e-26
CCDS33110.1 PTPRH gene_id:5794|Hs108|chr19 (1115) 626 118.3 5.3e-26
CCDS8674.1 PTPRO gene_id:5800|Hs108|chr12 (1188) 625 118.2 6.2e-26
CCDS8675.1 PTPRO gene_id:5800|Hs108|chr12 (1216) 625 118.2 6.3e-26
CCDS490.2 PTPRF gene_id:5792|Hs108|chr1 (1898) 627 118.7 6.8e-26
CCDS489.2 PTPRF gene_id:5792|Hs108|chr1 (1907) 627 118.7 6.8e-26
CCDS13430.1 PTPN1 gene_id:5770|Hs108|chr20 ( 435) 613 115.7 1.3e-25
CCDS2129.1 PTPN4 gene_id:5775|Hs108|chr2 ( 926) 614 116.2 1.9e-25
CCDS2161.1 PTPN18 gene_id:26469|Hs108|chr2 ( 460) 600 113.5 6.1e-25
>>CCDS41744.1 PTPN6 gene_id:5777|Hs108|chr12 (597 aa)
initn: 4013 init1: 4013 opt: 4013 Z-score: 3686.3 bits: 692.1 E(32554): 5.2e-199
Smith-Waterman score: 4013; 100.0% identity (100.0% similar) in 597 aa overlap (1-597:1-597)
10 20 30 40 50 60
pF1KE1 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 GGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 NKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
490 500 510 520 530 540
550 560 570 580 590
pF1KE1 ITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 ITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
550 560 570 580 590
>>CCDS44820.1 PTPN6 gene_id:5777|Hs108|chr12 (595 aa)
initn: 3981 init1: 3981 opt: 3981 Z-score: 3657.0 bits: 686.7 E(32554): 2.2e-197
Smith-Waterman score: 3981; 100.0% identity (100.0% similar) in 592 aa overlap (6-597:4-595)
10 20 30 40 50 60
pF1KE1 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 GGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE1 NKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE1 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE1 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
480 490 500 510 520 530
550 560 570 580 590
pF1KE1 ITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
540 550 560 570 580 590
>>CCDS44821.1 PTPN6 gene_id:5777|Hs108|chr12 (624 aa)
initn: 3944 init1: 3748 opt: 3748 Z-score: 3443.3 bits: 647.2 E(32554): 1.8e-185
Smith-Waterman score: 3748; 99.6% identity (99.6% similar) in 558 aa overlap (6-563:4-561)
10 20 30 40 50 60
pF1KE1 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 GGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE1 NKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE1 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE1 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
480 490 500 510 520 530
550 560 570 580 590
pF1KE1 ITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
:::::::::::::::::::: :
CCDS44 ITYPPAMKNAHAKASRTSSKSLESSAGTVAASPVRRGGQRGLPVPGPPVLSPDLHQLPVL
540 550 560 570 580 590
>>CCDS9163.1 PTPN11 gene_id:5781|Hs108|chr12 (593 aa)
initn: 2365 init1: 939 opt: 2205 Z-score: 2030.1 bits: 385.6 E(32554): 9.3e-107
Smith-Waterman score: 2205; 58.6% identity (81.0% similar) in 548 aa overlap (1-543:1-547)
10 20 30 40 50 60
pF1KE1 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
: :: ::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.:
CCDS91 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
:.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.::
CCDS91 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY
.:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .:
CCDS91 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES
::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :.
CCDS91 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI
: .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : :
CCDS91 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 PGSDYINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE
: ::::::: : .. .:.: .:::.::::. ::::::.:..:::::::::::.:
CCDS91 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ
::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:.
CCDS91 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE1 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI
. .::::::::.:::::.::......:::. :::..::::::::::::.::::.:.. :
CCDS91 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE1 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE
::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..: .
CCDS91 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE1 SEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLK
:: :: :
CCDS91 HEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
540 550 560 570 580 590
>>CCDS81741.1 PTPN11 gene_id:5781|Hs108|chr12 (597 aa)
initn: 2149 init1: 709 opt: 2188 Z-score: 2014.5 bits: 382.8 E(32554): 6.9e-106
Smith-Waterman score: 2188; 58.3% identity (80.4% similar) in 552 aa overlap (1-543:1-551)
10 20 30 40 50 60
pF1KE1 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
: :: ::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.:
CCDS81 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
:.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.::
CCDS81 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY
.:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .:
CCDS81 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES
::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :.
CCDS81 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI
: .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : :
CCDS81 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 PGSDYINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE
: ::::::: : .. .:.: .:::.::::. ::::::.:..:::::::::::.:
CCDS81 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSP----LDNGDLIREI
::.:..::: :::. . :: . : : : . .: :: :..: : .:. : .
CCDS81 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE1 WHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDML
:.:.. .::::::::.:::::.::......:::. :::..::::::::::::.::::.:
CCDS81 WQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDIL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE1 MENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQ
.. : ::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..
CCDS81 IDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKS
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE1 KGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSK
: . :: :: :
CCDS81 KRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
540 550 560 570 580 590
>>CCDS58280.1 PTPN11 gene_id:5781|Hs108|chr12 (460 aa)
initn: 1440 init1: 703 opt: 1833 Z-score: 1690.7 bits: 322.5 E(32554): 7.5e-88
Smith-Waterman score: 1833; 57.6% identity (80.2% similar) in 460 aa overlap (1-455:1-459)
10 20 30 40 50 60
pF1KE1 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
: :: ::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.:
CCDS58 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
:.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.::
CCDS58 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY
.:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .:
CCDS58 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES
::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :.
CCDS58 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI
: .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : :
CCDS58 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 PGSDYINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE
: ::::::: : .. .:.: .:::.::::. ::::::.:..:::::::::::.:
CCDS58 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ
::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:.
CCDS58 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE1 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI
. .::::::::.:::::.::......:::. :::..:::
CCDS58 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCR
420 430 440 450 460
480 490 500 510 520 530
pF1KE1 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE
>>CCDS47473.1 PTPRK gene_id:5796|Hs108|chr6 (1446 aa)
initn: 621 init1: 266 opt: 700 Z-score: 646.7 bits: 131.0 E(32554): 1.1e-29
Smith-Waterman score: 700; 41.4% identity (66.4% similar) in 304 aa overlap (214-514:858-1145)
190 200 210 220 230 240
pF1KE1 ETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAK
:: . ... : :: .: .. . :.
CCDS47 FSPRYENHSATAESSRLLDVPRYLCEGTESPYQTGQLHPA---IRVADLLQHINLMKTSD
830 840 850 860 870 880
250 260 270 280 290 300
pF1KE1 A-GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSD
. :: ::.::. . . . ... .:..:::: ::. .:::::::: ... :.::
CCDS47 SYGFKEEYESFFEGQSASWDV---AKKDQNRAKNRYGNIIAYDHSRVILQPVEDD-PSSD
890 900 910 920 930 940
310 320 330 340 350 360
pF1KE1 YINANYIKNQLLGPD-ENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRN
::::::: : . . :::.:: .. :: :::.: :::.: :::.: :: ::
CCDS47 YINANYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRV
950 960 970 980 990 1000
370 380 390 400 410 420
pF1KE1 KCVPYWPEVGMQRAYGPYSVTNCGEHDT-TEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
:: :::. ..:: ..:: : : . .:: .::. . .. :::. .... .::
CCDS47 KCYKYWPDD--TEVYGDFKVT-CVEMEPLAEYVVRTFTLERRGYNE-IREVKQFHFTGWP
1010 1020 1030 1040 1050
430 440 450 460 470 480
pF1KE1 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
::::: . :.:::. .. . . : ::::.:::::: :::: ::::.... .:.
CCDS47 DHGVPYHATGLLSFIRRV--KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGV
1060 1070 1080 1090 1100 1110
490 500 510 520 530 540
pF1KE1 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
.:: . .. .:..: .::::: :: ::. ::
CCDS47 ---VDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRI
1120 1130 1140 1150 1160 1170
550 560 570 580 590
pF1KE1 ITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
CCDS47 DSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDG
1180 1190 1200 1210 1220 1230
>--
initn: 133 init1: 100 opt: 383 Z-score: 356.3 bits: 77.2 E(32554): 1.6e-13
Smith-Waterman score: 383; 29.6% identity (64.2% similar) in 257 aa overlap (270-521:1205-1446)
240 250 260 270 280 290
pF1KE1 DTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIP
:.:. :::. ..:: :. .: :..
CCDS47 TNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGE--
1180 1190 1200 1210 1220 1230
300 310 320 330 340 350
pF1KE1 GSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKG
.:.:::: :. .. ..:..: : ::.:::..... . ::: . ::. .
CCDS47 SSNYINAA-----LMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLN-EVDLS
1240 1250 1260 1270 1280
360 370 380 390 400 410
pF1KE1 RNKCVPYWPEVGMQRAYGPYSVT--NCG-EHDTTEYKLRTLQVSPLDNGDLIREIWHYQY
.. : :::: :: : ::: .: .:. . :. . .: ... ..: :. . ..::
CCDS47 QG-CPQYWPEEGMLR-YGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM--VQQFQY
1290 1300 1310 1320 1330 1340
420 430 440 450 460 470
pF1KE1 LSWPDHG-VPSEPGGVLSFLDQINQRQESLPHA-GPIIVHCSAGIGRTGTIIVIDMLMEN
:.: .: ::. . :... :... :: .. : :.:: : ::.: . .: ...:
CCDS47 LGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEM
1350 1360 1370 1380 1390 1400
480 490 500 510 520 530
pF1KE1 ISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ
.. ... .:. .... .: .. .::.. ::.: : . ...:..
CCDS47 VKRQNV---VDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS
1410 1420 1430 1440
540 550 560 570 580 590
pF1KE1 ESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSL
>>CCDS78179.1 PTPRK gene_id:5796|Hs108|chr6 (1462 aa)
initn: 621 init1: 266 opt: 700 Z-score: 646.6 bits: 131.0 E(32554): 1.1e-29
Smith-Waterman score: 700; 41.4% identity (66.4% similar) in 304 aa overlap (214-514:874-1161)
190 200 210 220 230 240
pF1KE1 ETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAK
:: . ... : :: .: .. . :.
CCDS78 VPITDENHSATAESSRLLDVPRYLCEGTESPYQTGQLHPA---IRVADLLQHINLMKTSD
850 860 870 880 890 900
250 260 270 280 290 300
pF1KE1 A-GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSD
. :: ::.::. . . . ... .:..:::: ::. .:::::::: ... :.::
CCDS78 SYGFKEEYESFFEGQSASWDV---AKKDQNRAKNRYGNIIAYDHSRVILQPVEDD-PSSD
910 920 930 940 950
310 320 330 340 350 360
pF1KE1 YINANYIKNQLLGPD-ENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRN
::::::: : . . :::.:: .. :: :::.: :::.: :::.: :: ::
CCDS78 YINANYIDIWLYRDGYQRPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRV
960 970 980 990 1000 1010
370 380 390 400 410 420
pF1KE1 KCVPYWPEVGMQRAYGPYSVTNCGEHDT-TEYKLRTLQVSPLDNGDLIREIWHYQYLSWP
:: :::. ..:: ..:: : : . .:: .::. . .. :::. .... .::
CCDS78 KCYKYWPDD--TEVYGDFKVT-CVEMEPLAEYVVRTFTLERRGYNE-IREVKQFHFTGWP
1020 1030 1040 1050 1060 1070
430 440 450 460 470 480
pF1KE1 DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGL
::::: . :.:::. .. . . : ::::.:::::: :::: ::::.... .:.
CCDS78 DHGVPYHATGLLSFIRRV--KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGV
1080 1090 1100 1110 1120 1130
490 500 510 520 530 540
pF1KE1 DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGN
.:: . .. .:..: .::::: :: ::. ::
CCDS78 ---VDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRI
1140 1150 1160 1170 1180
550 560 570 580 590
pF1KE1 ITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
CCDS78 DSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDG
1190 1200 1210 1220 1230 1240
>--
initn: 133 init1: 100 opt: 383 Z-score: 356.3 bits: 77.2 E(32554): 1.6e-13
Smith-Waterman score: 383; 29.6% identity (64.2% similar) in 257 aa overlap (270-521:1221-1462)
240 250 260 270 280 290
pF1KE1 DTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIP
:.:. :::. ..:: :. .: :..
CCDS78 TNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGE--
1200 1210 1220 1230 1240
300 310 320 330 340 350
pF1KE1 GSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKG
.:.:::: :. .. ..:..: : ::.:::..... . ::: . ::. .
CCDS78 SSNYINAA-----LMDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLN-EVDLS
1250 1260 1270 1280 1290 1300
360 370 380 390 400 410
pF1KE1 RNKCVPYWPEVGMQRAYGPYSVT--NCG-EHDTTEYKLRTLQVSPLDNGDLIREIWHYQY
.. : :::: :: : ::: .: .:. . :. . .: ... ..: :. . ..::
CCDS78 QG-CPQYWPEEGMLR-YGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM--VQQFQY
1310 1320 1330 1340 1350
420 430 440 450 460 470
pF1KE1 LSWPDHG-VPSEPGGVLSFLDQINQRQESLPHA-GPIIVHCSAGIGRTGTIIVIDMLMEN
:.: .: ::. . :... :... :: .. : :.:: : ::.: . .: ...:
CCDS78 LGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEM
1360 1370 1380 1390 1400 1410
480 490 500 510 520 530
pF1KE1 ISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ
.. ... .:. .... .: .. .::.. ::.: : . ...:..
CCDS78 VKRQNV---VDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS
1420 1430 1440 1450 1460
540 550 560 570 580 590
pF1KE1 ESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSL
>>CCDS7658.1 PTPRE gene_id:5791|Hs108|chr10 (642 aa)
initn: 687 init1: 183 opt: 684 Z-score: 636.4 bits: 127.9 E(32554): 4e-29
Smith-Waterman score: 696; 35.7% identity (60.3% similar) in 403 aa overlap (201-596:33-416)
180 190 200 210 220
pF1KE1 VMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYL--RQPYYATRVNAADIENR
.:: :.: :.: . .:.
CCDS76 NRSSFSRLTWFRKQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEH-
10 20 30 40 50 60
230 240 250 260 270 280
pF1KE1 VLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSR
:: . . .: : : : :::.:: . .... . ... ::. :::: :::: ::::
CCDS76 -LEEEIRIRSADDCKQ-FREEFNSLPSGHIQGTFEL--ANKEENREKNRYPNILPNDHSR
70 80 90 100 110
290 300 310 320 330 340
pF1KE1 VILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRV
:::. :. :: ::::::.:: : :. : .::.:: . ::::::.:.:...: .
CCDS76 VILSQLDG-IPCSDYINASYID----GYKEKNK-FIAAQGPKQETVNDFWRMVWEQKSAT
120 130 140 150 160 170
350 360 370 380 390 400
pF1KE1 IVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTT--EYKLRTLQVSP-LDNG
::: : :. ..:: :::. : .:: .. : : .. .: .: . ..: : .:
CCDS76 IVMLTNLKERKEEKCHQYWPDQGCW-TYG--NIRVCVEDCVVLVDYTIRKFCIQPQLPDG
180 190 200 210 220
410 420 430 440 450 460
pF1KE1 -DLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGT
: . . .. :::: ::: : :.:.:: .. . . :::::.::::::.:::::
CCDS76 CKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKV--KTLNPVHAGPIVVHCSAGVGRTGT
230 240 250 260 270 280
470 480 490 500 510 520
pF1KE1 IIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKK
.:::: .: . .. .:. . .. .: :: ::::. :: ::: :. .. .
CCDS76 FIVIDAMMAMMHAEQ---KVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTE
290 300 310 320 330 340
530 540 550 560 570 580
pF1KE1 LEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSK-HKEDVYENLHTKNKREEKVKKQR
:.: . .: .. .:. :. . . . :. . ::.. . : .. .: .
CCDS76 LDVSSLEKHLQTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQII
350 360 370 380 390 400
590
pF1KE1 SADKEKSKGSLKRK
: .. :.::
CCDS76 PYDFNRVILSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHT
410 420 430 440 450 460
>--
initn: 481 init1: 179 opt: 454 Z-score: 425.7 bits: 88.9 E(32554): 2.2e-17
Smith-Waterman score: 454; 33.2% identity (65.5% similar) in 223 aa overlap (301-519:421-633)
280 290 300 310 320 330
pF1KE1 ENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCL
.:::::..: . .. .::.:: :
CCDS76 PANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFIDGY-----RQKDYFIATQGPL
400 410 420 430 440
340 350 360 370 380 390
pF1KE1 EATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTT
::.:::.: :. .:..::: :. :. ..:: ::: : . ..: .. .. .
CCDS76 AHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEG-SVTHGEITIEIKNDTLSE
450 460 470 480 490 500
400 410 420 430 440
pF1KE1 EYKLRTLQVS---PLDNGD-LIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLP
..: . :. : . .: . .... .::. :.:.: :..... . :.:..
CCDS76 AISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAV-QKQQQQT
510 520 530 540 550 560
450 460 470 480 490 500
pF1KE1 HAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQ
:: :::::: :::::.:... ..: ....:: .:. .... .: :: :::: :
CCDS76 GNHPITVHCSAGAGRTGTFIALSNILERVKAEGL---LDVFQAVKSLRLQRPHMVQTLEQ
570 580 590 600 610 620
510 520 530 540 550 560
pF1KE1 YKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVY
:.: : .. .::.
CCDS76 YEFCYKVVQDFIDIFSDYANFK
630 640
>>CCDS7657.1 PTPRE gene_id:5791|Hs108|chr10 (700 aa)
initn: 687 init1: 183 opt: 684 Z-score: 635.9 bits: 127.9 E(32554): 4.2e-29
Smith-Waterman score: 696; 35.7% identity (60.3% similar) in 403 aa overlap (201-596:91-474)
180 190 200 210 220
pF1KE1 VMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYL--RQPYYATRVNAADIENR
.:: :.: :.: . .:.
CCDS76 VLLLAAYFFRFRKQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEH-
70 80 90 100 110
230 240 250 260 270 280
pF1KE1 VLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSR
:: . . .: : : : :::.:: . .... . ... ::. :::: :::: ::::
CCDS76 -LEEEIRIRSADDCKQ-FREEFNSLPSGHIQGTFEL--ANKEENREKNRYPNILPNDHSR
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE1 VILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRV
:::. :. :: ::::::.:: : :. : .::.:: . ::::::.:.:...: .
CCDS76 VILSQLDG-IPCSDYINASYID----GYKEKNK-FIAAQGPKQETVNDFWRMVWEQKSAT
180 190 200 210 220
350 360 370 380 390 400
pF1KE1 IVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTT--EYKLRTLQVSP-LDNG
::: : :. ..:: :::. : .:: .. : : .. .: .: . ..: : .:
CCDS76 IVMLTNLKERKEEKCHQYWPDQGCW-TYG--NIRVCVEDCVVLVDYTIRKFCIQPQLPDG
230 240 250 260 270 280
410 420 430 440 450 460
pF1KE1 -DLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGT
: . . .. :::: ::: : :.:.:: .. . . :::::.::::::.:::::
CCDS76 CKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKV--KTLNPVHAGPIVVHCSAGVGRTGT
290 300 310 320 330 340
470 480 490 500 510 520
pF1KE1 IIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKK
.:::: .: . .. .:. . .. .: :: ::::. :: ::: :. .. .
CCDS76 FIVIDAMMAMMHAEQ---KVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTE
350 360 370 380 390 400
530 540 550 560 570 580
pF1KE1 LEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSK-HKEDVYENLHTKNKREEKVKKQR
:.: . .: .. .:. :. . . . :. . ::.. . : .. .: .
CCDS76 LDVSSLEKHLQTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQII
410 420 430 440 450 460
590
pF1KE1 SADKEKSKGSLKRK
: .. :.::
CCDS76 PYDFNRVILSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHT
470 480 490 500 510 520
>--
initn: 481 init1: 179 opt: 454 Z-score: 425.2 bits: 88.9 E(32554): 2.3e-17
Smith-Waterman score: 454; 33.2% identity (65.5% similar) in 223 aa overlap (301-519:479-691)
280 290 300 310 320 330
pF1KE1 ENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCL
.:::::..: . .. .::.:: :
CCDS76 PANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFIDGY-----RQKDYFIATQGPL
450 460 470 480 490 500
340 350 360 370 380 390
pF1KE1 EATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTT
::.:::.: :. .:..::: :. :. ..:: ::: : . ..: .. .. .
CCDS76 AHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEG-SVTHGEITIEIKNDTLSE
510 520 530 540 550 560
400 410 420 430 440
pF1KE1 EYKLRTLQVS---PLDNGD-LIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLP
..: . :. : . .: . .... .::. :.:.: :..... . :.:..
CCDS76 AISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAV-QKQQQQT
570 580 590 600 610 620
450 460 470 480 490 500
pF1KE1 HAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQ
:: :::::: :::::.:... ..: ....:: .:. .... .: :: :::: :
CCDS76 GNHPITVHCSAGAGRTGTFIALSNILERVKAEGL---LDVFQAVKSLRLQRPHMVQTLEQ
630 640 650 660 670
510 520 530 540 550 560
pF1KE1 YKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVY
:.: : .. .::.
CCDS76 YEFCYKVVQDFIDIFSDYANFK
680 690 700
597 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:39:03 2016 done: Mon Nov 7 02:39:03 2016
Total Scan time: 3.310 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]