Result of FASTA (omim) for
pFN21AB9865
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9865, 432 aa
1>>>pF1KB9865 432 - 432 aa - 432 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1288+/-0.000441; mu= 17.7239+/- 0.027
mean_var=63.2883+/-12.629, 0's: 0 Z-trim(109.2): 71 B-trim: 111 in 2/49
Lambda= 0.161218
statistics sampled from 17235 (17306) to 17235 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.203), width: 16
Scan time: 8.060
The best scores are: opt bits E(85289)
XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 2851 672.4 6.2e-193
NP_066292 (OMIM: 602323) ATP-sensitive inward rect ( 433) 2851 672.4 6.2e-193
XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 2851 672.4 6.2e-193
NP_001181887 (OMIM: 613236,613239) inward rectifie ( 433) 2805 661.7 1e-189
XP_005276976 (OMIM: 613236,613239) PREDICTED: inwa ( 535) 2805 661.7 1.2e-189
NP_000882 (OMIM: 170390,600681,609622,613980) inwa ( 427) 2033 482.1 1.2e-135
NP_037480 (OMIM: 603953) ATP-sensitive inward rect ( 436) 1552 370.3 5.6e-102
NP_004972 (OMIM: 600504) inward rectifier potassiu ( 445) 1421 339.8 8.4e-93
NP_690607 (OMIM: 600504) inward rectifier potassiu ( 445) 1421 339.8 8.4e-93
XP_016856736 (OMIM: 600932) PREDICTED: G protein-a ( 450) 1322 316.8 7.3e-86
NP_004974 (OMIM: 600932) G protein-activated inwar ( 393) 1320 316.3 9e-86
NP_000881 (OMIM: 600734,613485,613677) G protein-a ( 419) 1288 308.8 1.6e-83
XP_011541111 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1288 308.8 1.6e-83
XP_011541112 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1288 308.8 1.6e-83
NP_002231 (OMIM: 600877,614098) G protein-activate ( 423) 1272 305.1 2.2e-82
NP_002230 (OMIM: 601534) G protein-activated inwar ( 501) 1220 293.1 1.1e-78
NP_000516 (OMIM: 125853,600937,601820,606176,61058 ( 390) 1142 274.9 2.6e-73
NP_000211 (OMIM: 241200,600359) ATP-sensitive inwa ( 391) 1104 266.0 1.2e-70
NP_722448 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1101 265.3 1.8e-70
NP_722450 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1101 265.3 1.8e-70
NP_722451 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1101 265.3 1.8e-70
NP_722449 (OMIM: 241200,600359) ATP-sensitive inwa ( 389) 1101 265.3 1.9e-70
XP_016874773 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1081 260.7 5.2e-69
NP_004973 (OMIM: 600935) ATP-sensitive inward rect ( 424) 1081 260.7 5.2e-69
XP_005253415 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1081 260.7 5.2e-69
XP_016874772 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1081 260.7 5.2e-69
XP_016880102 (OMIM: 605722) PREDICTED: inward rect ( 418) 1073 258.8 1.9e-68
NP_001278553 (OMIM: 605722) inward rectifier potas ( 418) 1073 258.8 1.9e-68
XP_011523083 (OMIM: 605722) PREDICTED: inward rect ( 418) 1073 258.8 1.9e-68
NP_001278554 (OMIM: 605722) inward rectifier potas ( 418) 1073 258.8 1.9e-68
NP_001257351 (OMIM: 605722) inward rectifier potas ( 418) 1073 258.8 1.9e-68
XP_006721949 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9 2e-68
XP_016880101 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9 2e-68
NP_001278552 (OMIM: 605722) inward rectifier potas ( 453) 1073 258.9 2e-68
XP_006721950 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9 2e-68
XP_016880100 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9 2e-68
XP_016880099 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9 2e-68
XP_006721948 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9 2e-68
NP_733938 (OMIM: 605722) inward rectifier potassiu ( 453) 1073 258.9 2e-68
XP_016880098 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9 2e-68
NP_733937 (OMIM: 605722) inward rectifier potassiu ( 453) 1073 258.9 2e-68
NP_061128 (OMIM: 605722) inward rectifier potassiu ( 453) 1073 258.9 2e-68
NP_001278551 (OMIM: 605722) inward rectifier potas ( 453) 1073 258.9 2e-68
XP_005257394 (OMIM: 605722) PREDICTED: inward rect ( 453) 1073 258.9 2e-68
NP_001247438 (OMIM: 601534) G protein-activated in ( 308) 1019 246.2 8.7e-65
NP_001263364 (OMIM: 602106) ATP-sensitive inward r ( 375) 956 231.6 2.6e-60
XP_016883832 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 956 231.6 2.6e-60
XP_006724065 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 956 231.6 2.6e-60
NP_001263367 (OMIM: 602106) ATP-sensitive inward r ( 375) 956 231.6 2.6e-60
NP_733932 (OMIM: 602106) ATP-sensitive inward rect ( 375) 956 231.6 2.6e-60
>>XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensitive i (433 aa)
initn: 2217 init1: 2217 opt: 2851 Z-score: 3584.8 bits: 672.4 E(85289): 6.2e-193
Smith-Waterman score: 2851; 98.6% identity (99.1% similar) in 433 aa overlap (1-432:1-433)
10 20 30 40 50 60
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 GMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCSAK
::::::::::::::::::::::::::::::::: :::::::: :::::::::::::::::
XP_011 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG
:::::::::: ::::::.:::::::::::::::::::::::.:: :::::::::::::::
XP_011 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
370 380 390 400 410 420
420 430
pF1KB9 VLEQRPYRRESEI
:::::::::::::
XP_011 VLEQRPYRRESEI
430
>>NP_066292 (OMIM: 602323) ATP-sensitive inward rectifie (433 aa)
initn: 2217 init1: 2217 opt: 2851 Z-score: 3584.8 bits: 672.4 E(85289): 6.2e-193
Smith-Waterman score: 2851; 98.6% identity (99.1% similar) in 433 aa overlap (1-432:1-433)
10 20 30 40 50 60
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 GMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCSAK
::::::::::::::::::::::::::::::::: :::::::: :::::::::::::::::
NP_066 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG
:::::::::: ::::::.:::::::::::::::::::::::.:: :::::::::::::::
NP_066 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
370 380 390 400 410 420
420 430
pF1KB9 VLEQRPYRRESEI
:::::::::::::
NP_066 VLEQRPYRRESEI
430
>>XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensitive i (433 aa)
initn: 2217 init1: 2217 opt: 2851 Z-score: 3584.8 bits: 672.4 E(85289): 6.2e-193
Smith-Waterman score: 2851; 98.6% identity (99.1% similar) in 433 aa overlap (1-432:1-433)
10 20 30 40 50 60
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 GMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCSAK
::::::::::::::::::::::::::::::::: :::::::: :::::::::::::::::
XP_005 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG
:::::::::: ::::::.:::::::::::::::::::::::.:: :::::::::::::::
XP_005 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
370 380 390 400 410 420
420 430
pF1KB9 VLEQRPYRRESEI
:::::::::::::
XP_005 VLEQRPYRRESEI
430
>>NP_001181887 (OMIM: 613236,613239) inward rectifier po (433 aa)
initn: 2180 init1: 2180 opt: 2805 Z-score: 3526.9 bits: 661.7 E(85289): 1e-189
Smith-Waterman score: 2805; 97.2% identity (98.2% similar) in 433 aa overlap (1-432:1-433)
10 20 30 40 50 60
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANM
:::::::::::::: :::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MTAASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIAFANM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGR
:::::::::::::::::::::::::::::::::::::::.:::::::::::::::::.::
NP_001 DEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGHGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAI
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 TPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQSIVGCIIDSFMIGAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILE
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 GMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCSAK
::::::::::::::::::::::::::::::::: :::::::: :::::::::::::::::
NP_001 GMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 DLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAGGG
:::::::::: ::::::.:::::::::::::::::::::::.:: :::::::::::::::
NP_001 DLVENKFLLPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGG
370 380 390 400 410 420
420 430
pF1KB9 VLEQRPYRRESEI
::::::::: :::
NP_001 VLEQRPYRRGSEI
430
>>XP_005276976 (OMIM: 613236,613239) PREDICTED: inward r (535 aa)
initn: 2180 init1: 2180 opt: 2805 Z-score: 3525.6 bits: 661.7 E(85289): 1.2e-189
Smith-Waterman score: 2805; 97.2% identity (98.2% similar) in 433 aa overlap (1-432:103-535)
10 20 30
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANG
:::::::::::::: :::::::::::::::
XP_005 FRPCVPAPQRHGAALPGASLGVSQGPPTPGMTAASRANPYSIVSLEEDGLHLVTMSGANG
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB9 FGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLA
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_005 FGNGKVHTRRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLA
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB9 FLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRC
:::::::::.:::::::::::::::::.::::::::::::::::::::::::::::::::
XP_005 FLASWLLFGVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRC
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB9 VTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLC
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTEECLVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLC
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB9 LMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITI
320 330 340 350 360 370
280 290 300 310 320 330
pF1KB9 LHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPV
380 390 400 410 420 430
340 350 360 370 380
pF1KB9 LFE-KNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKNELAFLSRDEED
::: :::::::: ::::::::::::::::::::::::::: ::::::.::::::::::::
XP_005 LFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSANSFCYENELAFLSRDEED
440 450 460 470 480 490
390 400 410 420 430
pF1KB9 EADGDQDGRSREGLIPQARHDFDRLQAGGGVLEQRPYRRESEI
:::::::::::.:: :::::::::::::::::::::::: :::
XP_005 EADGDQDGRSRDGLSPQARHDFDRLQAGGGVLEQRPYRRGSEI
500 510 520 530
>>NP_000882 (OMIM: 170390,600681,609622,613980) inward r (427 aa)
initn: 1573 init1: 1265 opt: 2033 Z-score: 2556.6 bits: 482.1 E(85289): 1.2e-135
Smith-Waterman score: 2033; 70.2% identity (88.1% similar) in 430 aa overlap (6-432:5-427)
10 20 30 40 50
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGK--VHTRRRCRNRFVKKNGQCNIEFA
:.: ::::::::::..:.::. :::::::: ::::..::.:::::.:.::..:
NP_000 MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFI
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 NMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGR
:. ::.::::::.::::::::::.::.:: :::. :::.:: .::.::. ::::. : .
NP_000 NVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLD-ASKE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 GRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIG
:.. :: .:..: ::::::::::::::::.::::.:::.:::::: :::::::::.:.::
NP_000 GKA-CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 AIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVT
:.:::::.:::: .::.::::::.:.::::::::::::::::::.:::::::::.: :.:
NP_000 AVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRIT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 EEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVI
::::::::::::.::::.:.:::::::::::.::::: :::. .:.::... :::::::
NP_000 SEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 LEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHFHKTYEVPSTPRCS
::::::::::::: ::::::::::::::.:::::: :. ::.:: .::::::::.:: ::
NP_000 LEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 AKDLVENKFLLPRANSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQARHDFDRLQAG
:.::.:.:..: ::::::.::.:. :..:.: .: .. : . : :.: . .
NP_000 ARDLAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTD--TPP---DIDLHNQA
360 370 380 390 400 410
420 430
pF1KB9 GGVLEQRPYRRESEI
. :: :: ::::::
NP_000 SVPLEPRPLRRESEI
420
>>NP_037480 (OMIM: 603953) ATP-sensitive inward rectifie (436 aa)
initn: 1623 init1: 1075 opt: 1552 Z-score: 1951.9 bits: 370.3 E(85289): 5.6e-102
Smith-Waterman score: 1607; 62.8% identity (82.3% similar) in 384 aa overlap (29-401:34-415)
10 20 30 40 50
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRR-RCRNRFVKKNGQCNIEF
::.. . :.. : :.:::::.:.::..:
NP_037 ARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCNVRF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 ANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEG
.:. .. :::.:.::::::.:::.: :.:: .:::::::::. ::.:: :::: :
NP_037 VNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDL--AAP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 RGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMI
.:: .: .:.:::::..::::.::::.: ::::::.:: :: : :.::..:.:..
NP_037 PPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 GAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRV
::.:::::.:::: .::.::.:::::::: .:::::::::::.::.:::::::::..:::
NP_037 GAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 TEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVV
: ::::::::. :.::::: : :::::::::::.:::: ::::. ..: .: :::.::
NP_037 TPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 ILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEK-NQYKIDYLHFHKTYEVPSTPRC
:::::::::::::: ::::: .:.:::::::::::.. .::..:: :::.:::::.:: :
NP_037 ILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVC
310 320 330 340 350 360
360 370 380 390 400
pF1KB9 SAKDLVEN--------KFLLPRA-NSFCYKNELAFLSRDEEDEADGDQDGRSREGLIPQA
:::.: : : .: . ..:::.::::. .:::: : ..: . :
NP_037 SAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGAA
370 380 390 400 410 420
410 420 430
pF1KB9 RHDFDRLQAGGGVLEQRPYRRESEI
NP_037 SPRVLTPTLALTLPP
430
>>NP_004972 (OMIM: 600504) inward rectifier potassium ch (445 aa)
initn: 1869 init1: 1208 opt: 1421 Z-score: 1787.1 bits: 339.8 E(85289): 8.4e-93
Smith-Waterman score: 1821; 64.5% identity (82.7% similar) in 440 aa overlap (33-432:7-445)
10 20 30 40 50 60
pF1KB9 AASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIEFANMD
::..:. ::. ::::::::::::. :::..
NP_004 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
10 20 30
70 80 90 100 110
pF1KB9 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLE--------
.:::::.::.:::::: ::::::.::: :::.:::.::..:: :: :::::
NP_004 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
40 50 60 70 80 90
120 130 140 150 160
pF1KB9 --PAEGRGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQ
:: : : . ::.:.:.::..:::::.:::::::::.::::::::.::. ::.:
NP_004 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB9 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
:::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
NP_004 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB9 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
:::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
NP_004 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB9 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHF
..::..:::::::::::::::::::::::::::.:::::::::::.:: :..::.:: .:
NP_004 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
280 290 300 310 320 330
350 360 370 380 390
pF1KB9 HKTYEVPSTPRCSAKDLVENKFLL-----PRANSFCYKNELAFLSRDEEDEAD-------
:::::: .:: :::..: :.:. . : ..:::.::::..:..::. .
NP_004 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
340 350 360 370 380 390
400 410 420 430
pF1KB9 -----GDQDGRSRE-GLIPQ---ARH-DFDRLQAGGGVLEQRPYRRESEI
: . : ..: :.: . . : :..:.::. :.. ::::: :
NP_004 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLP-LDNISYRRESAI
400 410 420 430 440
>>NP_690607 (OMIM: 600504) inward rectifier potassium ch (445 aa)
initn: 1869 init1: 1208 opt: 1421 Z-score: 1787.1 bits: 339.8 E(85289): 8.4e-93
Smith-Waterman score: 1821; 64.5% identity (82.7% similar) in 440 aa overlap (33-432:7-445)
10 20 30 40 50 60
pF1KB9 AASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIEFANMD
::..:. ::. ::::::::::::. :::..
NP_690 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
10 20 30
70 80 90 100 110
pF1KB9 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLE--------
.:::::.::.:::::: ::::::.::: :::.:::.::..:: :: :::::
NP_690 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
40 50 60 70 80 90
120 130 140 150 160
pF1KB9 --PAEGRGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQ
:: : : . ::.:.:.::..:::::.:::::::::.::::::::.::. ::.:
NP_690 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB9 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
:::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
NP_690 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB9 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
:::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
NP_690 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB9 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-KNQYKIDYLHF
..::..:::::::::::::::::::::::::::.:::::::::::.:: :..::.:: .:
NP_690 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
280 290 300 310 320 330
350 360 370 380 390
pF1KB9 HKTYEVPSTPRCSAKDLVENKFLL-----PRANSFCYKNELAFLSRDEEDEAD-------
:::::: .:: :::..: :.:. . : ..:::.::::..:..::. .
NP_690 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
340 350 360 370 380 390
400 410 420 430
pF1KB9 -----GDQDGRSRE-GLIPQ---ARH-DFDRLQAGGGVLEQRPYRRESEI
: . : ..: :.: . . : :..:.::. :.. ::::: :
NP_690 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLP-LDNISYRRESAI
400 410 420 430 440
>>XP_016856736 (OMIM: 600932) PREDICTED: G protein-activ (450 aa)
initn: 1274 init1: 1145 opt: 1322 Z-score: 1662.5 bits: 316.8 E(85289): 7.3e-86
Smith-Waterman score: 1322; 51.8% identity (78.4% similar) in 398 aa overlap (2-397:39-428)
10 20 30
pF1KB9 MTAASRANPYSIVSSEEDGLHLVTMSGANGF
... : .: . :.. :. .. ..: :
XP_016 EGPLIRQTFIKPLQDPRRRLGAQRRAAGGSSSGPRRTP-GARSARPDAAAMAQENAA--F
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 GNGKVHT-RRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLA
. :. . ::: :.:.:.:.:.::.. .:. : . :::.:.::: ::..:: ::.: ::
XP_016 SPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 FLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRC
. .::.:: :.:.:: ..:::: : . :::: ...::.:::::::::.:::::: :
XP_016 YALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 VTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLC
.:..:: .. ... :.:.: ....::.: ...:...:.::: ::.:: .:::.::::.::
XP_016 ITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLC
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 LMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITI
::.:::.::.:::::: .::.::. : : :::.::: : :..:::: : ::.:::::..:
XP_016 LMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB9 LHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPV
:::: :::.. ::. :: ::::::::::::::::.:: :::::::..:.:::::: :
XP_016 SHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSV
310 320 330 340 350 360
340 350 360 370 380
pF1KB9 L-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVENKFLLPRANSFCYKNELAFLSRDEED
: .: . :..:: ::.:.::: :: :::..:.: : .. : . . :.. :.
XP_016 LTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAA---ARLDAHLYWSIPSRLDEKVEE
370 380 390 400 410 420
390 400 410 420 430
pF1KB9 EADGDQDGRSREGLIPQARHDFDRLQAGGGVLEQRPYRRESEI
:. :. :
XP_016 EGAGEGAGGEAGADKEQNGCLPPPESESKV
430 440 450
432 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:36:38 2016 done: Sat Nov 5 02:36:39 2016
Total Scan time: 8.060 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]