Result of FASTA (omim) for
pFN21AB5402
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5402, 384 aa
1>>>pF1KB5402 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5413+/-0.000348; mu= 11.3413+/- 0.022
mean_var=112.7297+/-22.965, 0's: 0 Z-trim(116.7): 148 B-trim: 0 in 0/56
Lambda= 0.120797
statistics sampled from 27816 (27998) to 27816 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.328), width: 16
Scan time: 8.880
The best scores are: opt bits E(85289)
NP_004410 (OMIM: 603069) dual specificity protein ( 384) 2552 455.6 9e-128
NP_001385 (OMIM: 602747) dual specificity protein ( 394) 960 178.2 3e-44
NP_004408 (OMIM: 600714) dual specificity protein ( 367) 949 176.2 1.1e-43
XP_011542730 (OMIM: 602747) PREDICTED: dual specif ( 303) 749 141.3 2.9e-33
NP_476499 (OMIM: 602747) dual specificity protein ( 303) 749 141.3 2.9e-33
NP_004409 (OMIM: 603068) dual specificity protein ( 314) 676 128.6 2e-29
XP_016859035 (OMIM: 603068) PREDICTED: dual specif ( 342) 615 118.0 3.4e-26
NP_009138 (OMIM: 608867) dual specificity protein ( 482) 456 90.4 9.8e-18
NP_001305432 (OMIM: 300134) dual specificity prote ( 384) 424 84.7 3.9e-16
XP_011529426 (OMIM: 300134) PREDICTED: dual specif ( 384) 424 84.7 3.9e-16
NP_001386 (OMIM: 300134) dual specificity protein ( 384) 424 84.7 3.9e-16
XP_011529425 (OMIM: 300134) PREDICTED: dual specif ( 415) 424 84.8 4.1e-16
NP_001938 (OMIM: 602749) dual specificity protein ( 419) 424 84.8 4.2e-16
NP_001937 (OMIM: 602748,615269) dual specificity p ( 381) 408 82.0 2.7e-15
XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665) 368 75.1 5.2e-13
XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665) 368 75.1 5.2e-13
NP_085143 (OMIM: 607175) dual specificity protein ( 665) 368 75.1 5.2e-13
XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665) 368 75.1 5.2e-13
XP_011518235 (OMIM: 602038) PREDICTED: dual specif ( 625) 334 69.2 3e-11
XP_011518234 (OMIM: 602038) PREDICTED: dual specif ( 625) 334 69.2 3e-11
NP_004411 (OMIM: 602038) dual specificity protein ( 625) 334 69.2 3e-11
NP_008957 (OMIM: 606618) dual specificity protein ( 198) 322 66.8 5.2e-11
XP_011522536 (OMIM: 606618) PREDICTED: dual specif ( 198) 322 66.8 5.2e-11
XP_005257034 (OMIM: 606618) PREDICTED: dual specif ( 198) 322 66.8 5.2e-11
NP_001154802 (OMIM: 606778) protein phosphatase Sl ( 692) 329 68.4 6e-11
NP_001154803 (OMIM: 606778) protein phosphatase Sl ( 703) 329 68.4 6e-11
XP_016874981 (OMIM: 606778) PREDICTED: protein pho ( 923) 329 68.5 7.5e-11
XP_011536803 (OMIM: 606778) PREDICTED: protein pho ( 969) 329 68.5 7.8e-11
XP_011536802 (OMIM: 606778) PREDICTED: protein pho ( 969) 329 68.5 7.8e-11
XP_005269042 (OMIM: 606778) PREDICTED: protein pho ( 969) 329 68.5 7.8e-11
XP_016874980 (OMIM: 606778) PREDICTED: protein pho (1033) 329 68.5 8.2e-11
XP_005269041 (OMIM: 606778) PREDICTED: protein pho (1049) 329 68.5 8.3e-11
NP_061857 (OMIM: 606778) protein phosphatase Sling (1049) 329 68.5 8.3e-11
XP_011536799 (OMIM: 606778) PREDICTED: protein pho (1060) 329 68.5 8.4e-11
XP_016880742 (OMIM: 606779) PREDICTED: protein pho ( 529) 324 67.4 8.8e-11
XP_016880743 (OMIM: 606779) PREDICTED: protein pho ( 480) 320 66.7 1.3e-10
XP_016880741 (OMIM: 606779) PREDICTED: protein pho (1328) 324 67.7 1.8e-10
XP_011523708 (OMIM: 606779) PREDICTED: protein pho (1347) 324 67.7 1.8e-10
XP_011523709 (OMIM: 606779) PREDICTED: protein pho (1347) 324 67.7 1.8e-10
XP_011523707 (OMIM: 606779) PREDICTED: protein pho (1394) 324 67.7 1.9e-10
XP_006722212 (OMIM: 606779) PREDICTED: protein pho (1401) 324 67.7 1.9e-10
XP_011523706 (OMIM: 606779) PREDICTED: protein pho (1405) 324 67.7 1.9e-10
NP_203747 (OMIM: 606779) protein phosphatase Sling (1423) 324 67.7 1.9e-10
XP_011523704 (OMIM: 606779) PREDICTED: protein pho (1430) 324 67.7 1.9e-10
XP_005258116 (OMIM: 606779) PREDICTED: protein pho (1430) 324 67.7 1.9e-10
XP_016880740 (OMIM: 606779) PREDICTED: protein pho (1449) 324 67.7 2e-10
NP_001269058 (OMIM: 606779) protein phosphatase Sl (1450) 324 67.7 2e-10
XP_005258115 (OMIM: 606779) PREDICTED: protein pho (1450) 324 67.7 2e-10
XP_005253545 (OMIM: 607175) PREDICTED: dual specif ( 517) 313 65.5 3.3e-10
XP_016875477 (OMIM: 607175) PREDICTED: dual specif ( 517) 313 65.5 3.3e-10
>>NP_004410 (OMIM: 603069) dual specificity protein phos (384 aa)
initn: 2552 init1: 2552 opt: 2552 Z-score: 2414.9 bits: 455.6 E(85289): 9e-128
Smith-Waterman score: 2552; 99.5% identity (99.5% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KB5 MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTPLLACLPAGP
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_004 SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 RVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACMTHLHYKWIPVEDSHTADISS
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_004 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASV
310 320 330 340 350 360
370 380
pF1KB5 LAPVPTHSTVSELSRSPVATATSC
::::::::::::::::::::::::
NP_004 LAPVPTHSTVSELSRSPVATATSC
370 380
>>NP_001385 (OMIM: 602747) dual specificity protein phos (394 aa)
initn: 900 init1: 634 opt: 960 Z-score: 915.4 bits: 178.2 E(85289): 3e-44
Smith-Waterman score: 968; 46.7% identity (67.5% similar) in 381 aa overlap (19-384:41-394)
10 20 30 40
pF1KB5 MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLN
....:..:::::.:: .:. . ::.:: :
NP_001 DCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVRCN
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB5 SVVLRRARGGAVSARYVLP-DEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARV
..: :::.: .:: . .:: .: .:::: . : .::.: :. : . ..:::.:.. .
NP_001 TIVRRRAKG-SVSLEQILPAEEEVRARLRS---GLYSAVIVYDERSPRAESLREDSTVSL
80 90 100 110 120
110 120 130 140 150 160
pF1KB5 VLTPLLACLPAGPRVYFLKGGYETFYSEYPECCVDVK-------PISQEKIESERALISQ
:. : . .:::::: : ::::: : .: :. : :.
NP_001 VVQALRRNAERTD-ICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB5 CGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACM
:: :. .::::::::::::::::::::.. ..: : :::::::: .
NP_001 CGTPL--------HDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFE
190 200 210 220 230
230 240 250 260 270 280
pF1KB5 THLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMK
: .:: :::::.: ::::: :.:::..:: :.. :.:::::.:::::: :::.::::
NP_001 GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMM
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 TKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIG
:. ::.:::...:::::..::::.:::::::.::..: . :: .:::. : :
NP_001 KKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAT-------SCAAEAASPS--G
300 310 320 330 340
350 360 370 380
pF1KB5 HLQT-----LSPDMQGAYCTFPASVLAPVPTHSTVSELS--RSPVATATSC
:. .: : .. .::.:: .::. : : .::..:. ::
NP_001 PLRERGKTPATPTSQFVF-SFPVSV----GVHSAPSSLPYLHSPITTSPSC
350 360 370 380 390
>>NP_004408 (OMIM: 600714) dual specificity protein phos (367 aa)
initn: 898 init1: 657 opt: 949 Z-score: 905.4 bits: 176.2 E(85289): 1.1e-43
Smith-Waterman score: 1003; 45.4% identity (69.5% similar) in 394 aa overlap (1-384:3-367)
10 20 30 40 50
pF1KB5 MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGG
:.: .::. :: .: : ::.:..:::: ..:: :... ::.:: ....: :::.:
NP_004 MVMEVGTLDAGGLRALL-GERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKG-
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 AVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTPLLACLPA
:.. ....:. :.::: .:. :::.::. : . ..... ..:. : :
NP_004 AMGLEHIVPNAELRGRLL---AGAYHAVVLLDERSAALDGAKRDGT--LALAAGALCREA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 -GPRVYFLKGGYETFYSEYPECCVDVK-------PISQEKIESERALISQCGKPVVNVSY
. .:.:::::::.: . :: : . :.: .: .. :.:. :.
NP_004 RAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPL-----
120 130 140 150 160
180 190 200 210 220 230
pF1KB5 RPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACMTHLHYKWIPV
::::::::::::::::::::::. ..: : ::::.::: . : .:: :::
NP_004 ---YDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 EDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAF
::.: ::::: :.::::::: ... ::.:.:::.:::::: :::.::::.:.. .: :::
NP_004 EDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAF
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 DYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQ
...:::::..::::.:::::::.::..: : :..:: :: .. :. .
NP_004 EFVKQRRSIISPNFSFMGQLLQFESQVLA-------PHCSAEA-GSPAMAVLDRGTSTT-
290 300 310 320 330
360 370 380
pF1KB5 GAYCTFPASVLAPVPTHSTVSELS--RSPVATATSC
. .::.:. :.::: : :: .::..:. ::
NP_004 -TVFNFPVSI----PVHSTNSALSYLQSPITTSPSC
340 350 360
>>XP_011542730 (OMIM: 602747) PREDICTED: dual specificit (303 aa)
initn: 734 init1: 634 opt: 749 Z-score: 718.2 bits: 141.3 E(85289): 2.9e-33
Smith-Waterman score: 757; 49.8% identity (67.0% similar) in 273 aa overlap (126-384:53-303)
100 110 120 130 140
pF1KB5 WQKLREESAARVVLTPLLACLPAGPRVYFLKGGYETFYSEYPECCVDVK-------PISQ
.:::: : ::::: : .: :.
XP_011 GRDCKPVRAPSMALGVSQLAGRSRCLCSESQGGYERFSSEYPEFCSKTKALAAIPPPVPP
30 40 50 60 70 80
150 160 170 180 190 200
pF1KB5 EKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITAL
: :.:: :. .::::::::::::::::::::.. ..: : ::::
XP_011 SATEPLDLGCSSCGTPL--------HDQGGPVEILPFLYLGSAYHAARRDMLDALGITAL
90 100 110 120 130
210 220 230 240 250 260
pF1KB5 LNVSRRTSEACMTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGIS
:::: . : .:: :::::.: ::::: :.:::..:: :.. :.:::::.::::
XP_011 LNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGIS
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB5 RSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPS
:: :::.:::: :. ::.:::...:::::..::::.:::::::.::..: . :
XP_011 RSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAT-------S
200 210 220 230 240
330 340 350 360 370 380
pF1KB5 CQGEAAGSSLIGHLQT-----LSPDMQGAYCTFPASVLAPVPTHSTVSELS--RSPVATA
: .:::. : : :. .: : .. .::.: : .::. : : .::..:.
XP_011 CAAEAASPS--GPLRERGKTPATPTSQFVF-SFPVS----VGVHSAPSSLPYLHSPITTS
250 260 270 280 290 300
pF1KB5 TSC
::
XP_011 PSC
>>NP_476499 (OMIM: 602747) dual specificity protein phos (303 aa)
initn: 734 init1: 634 opt: 749 Z-score: 718.2 bits: 141.3 E(85289): 2.9e-33
Smith-Waterman score: 757; 49.8% identity (67.0% similar) in 273 aa overlap (126-384:53-303)
100 110 120 130 140
pF1KB5 WQKLREESAARVVLTPLLACLPAGPRVYFLKGGYETFYSEYPECCVDVK-------PISQ
.:::: : ::::: : .: :.
NP_476 GRDCKPVRAPSMALGVSQLAGRSRCLCSESQGGYERFSSEYPEFCSKTKALAAIPPPVPP
30 40 50 60 70 80
150 160 170 180 190 200
pF1KB5 EKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITAL
: :.:: :. .::::::::::::::::::::.. ..: : ::::
NP_476 SATEPLDLGCSSCGTPL--------HDQGGPVEILPFLYLGSAYHAARRDMLDALGITAL
90 100 110 120 130
210 220 230 240 250 260
pF1KB5 LNVSRRTSEACMTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGIS
:::: . : .:: :::::.: ::::: :.:::..:: :.. :.:::::.::::
NP_476 LNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGIS
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB5 RSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPS
:: :::.:::: :. ::.:::...:::::..::::.:::::::.::..: . :
NP_476 RSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAT-------S
200 210 220 230 240
330 340 350 360 370 380
pF1KB5 CQGEAAGSSLIGHLQT-----LSPDMQGAYCTFPASVLAPVPTHSTVSELS--RSPVATA
: .:::. : : :. .: : .. .::.: : .::. : : .::..:.
NP_476 CAAEAASPS--GPLRERGKTPATPTSQFVF-SFPVS----VGVHSAPSSLPYLHSPITTS
250 260 270 280 290 300
pF1KB5 TSC
::
NP_476 PSC
>>NP_004409 (OMIM: 603068) dual specificity protein phos (314 aa)
initn: 865 init1: 591 opt: 676 Z-score: 649.3 bits: 128.6 E(85289): 2e-29
Smith-Waterman score: 858; 48.3% identity (69.8% similar) in 321 aa overlap (6-318:9-312)
10 20 30 40 50
pF1KB5 MKVTSLDGRQLRKMLRK-EAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRAR
:. : .:: . : : ..:::::.::: .::.. : :... ::::
NP_004 MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 G--GAVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTPLLA
: .:: : .:::.: :.::.. : .: .::::.:: .:: .: :.:.:. ::
NP_004 GPPAAVLA-CLLPDRALRTRLVR---GELARAVVLDEGSASVAELRPDSPAHVLLAALLH
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 CLPAGPR-VYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPA
::: ::::.::.. : . :. : .. : :: : . : :.
NP_004 ETRAGPTAVYFLRGGFDGFQGCCPDLCSEA-PAP--------ALPPTGDKTSRSDSRAPV
120 130 140 150 160
180 190 200 210 220
pF1KB5 YDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACMTHLH----YKWIP
:::::::::::.:.::: :.: . : :::.:::: .: .:.. :: ::
NP_004 YDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVS----ASCPNHFEGLFRYKSIP
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 VEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEA
:::.. ..::. ::::: ::: :...::.:::::.:::::: :::.::::.... :: ::
NP_004 VEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEA
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB5 FDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDM
::..::::...::::.:::::::.:...:
NP_004 FDFVKQRRGVISPNFSFMGQLLQFETQVLCH
290 300 310
>>XP_016859035 (OMIM: 603068) PREDICTED: dual specificit (342 aa)
initn: 821 init1: 591 opt: 615 Z-score: 591.3 bits: 118.0 E(85289): 3.4e-26
Smith-Waterman score: 793; 45.0% identity (66.3% similar) in 347 aa overlap (6-318:9-340)
10 20 30 40 50
pF1KB5 MKVTSLDGRQLRKMLRK-EAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRAR
:. : .:: . : : ..:::::.::: .::.. : :... ::::
XP_016 MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRAR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 G--GAVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTPLLA
: .:: : .:::.: :.::.. : .: .::::.:: .:: .: :.:.:. ::
XP_016 GPPAAVLA-CLLPDRALRTRLVR---GELARAVVLDEGSASVAELRPDSPAHVLLAALLH
70 80 90 100 110
120 130 140 150
pF1KB5 CLPAGPR-VYFLKGGYETFYSEYPECCVDVKPISQEKIESERALI--------------S
::: ::::.: : .: . : :. . ..::: .
XP_016 ETRAGPTAVYFLRG--EQAGRPWP-----APPDSSPAFPADRALPLLAGGFDGFQGCCPD
120 130 140 150 160
160 170 180 190 200
pF1KB5 QCGK-------PVVNVSYR-----PAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITA
:.. :. . . : :.:::::::::::.:.::: :.: . : :::
XP_016 LCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITA
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB5 LLNVSRRTSEACMTHLH----YKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHC
.:::: .: .:.. :: :::::.. ..::. ::::: ::: :...::.:::::
XP_016 VLNVS----ASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHC
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB5 EAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPN
.:::::: :::.::::.... :: ::::..::::...::::.:::::::.:...:
XP_016 QAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB5 PQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATS
>>NP_009138 (OMIM: 608867) dual specificity protein phos (482 aa)
initn: 473 init1: 301 opt: 456 Z-score: 439.4 bits: 90.4 E(85289): 9.8e-18
Smith-Waterman score: 456; 27.7% identity (61.1% similar) in 321 aa overlap (24-331:173-477)
10 20 30 40 50
pF1KB5 MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNL-NSVVL
:..::::.. . :...:....: ...
NP_009 QLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPFMEYNKSHIQGAVHINCADKISR
150 160 170 180 190 200
60 70 80 90 100
pF1KB5 RRARGGAVSARYVLPDEAAR---ARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVL
:: . : ... .. . .. :.... ..: :... . ... . ..::
NP_009 RRLQQGKITVLDLISCREGKDSFKRIFSK------EIIVYDENTNEPSRVMPSQPLHIVL
210 220 230 240 250
110 120 130 140 150 160
pF1KB5 TPLLACLPAGPRVYFLKGGYETFYSEYPECCVDVKPISQEKIE---SERALISQCGKPVV
: : . :::: .: ... . : : . :: : . : : .:.
NP_009 ESLKR---EGKEPLVLKGGLSSFKQNHENLC-DNSLQLQECREVGGGASAASSLLPQPIP
260 270 280 290 300 310
170 180 190 200 210 220
pF1KB5 NVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACMTH----
.. : ... . :::::.::. :. . . :.: ..:: :.. . :
NP_009 TT---PDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINV---TTHLPLYHYEKG
320 330 340 350 360
230 240 250 260 270 280
pF1KB5 -LHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKT
..:: .:. ::. .. ..:.::..::. ... : .:.::.::.::: :: .:::::
NP_009 LFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKH
370 380 390 400 410 420
290 300 310 320 330 340
pF1KB5 KQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPS-TPNPQPPSCQGEAAGSSLIG
.. . .:. ..: .: ..:::..::::::..: .. . :: :. .:
NP_009 TRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVETVV
430 440 450 460 470 480
350 360 370 380
pF1KB5 HLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC
>>NP_001305432 (OMIM: 300134) dual specificity protein p (384 aa)
initn: 538 init1: 315 opt: 424 Z-score: 410.7 bits: 84.7 E(85289): 3.9e-16
Smith-Waterman score: 545; 33.0% identity (57.1% similar) in 382 aa overlap (15-357:11-383)
10 20 30 40 50
pF1KB5 MKVTSLDGRQLRKMLRKEAAA---RCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARG
::.: . : ..:::: . .. . :.:.: : ...::: :
NP_001 MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 GAVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLR-----EESAARVVLTPL
:..:.: .:: :: : :.. :::. . .. . :: :. :: :
NP_001 GSLSVRALLPGPP-----LQPPPP--APVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTL
60 70 80 90 100
120 130 140
pF1KB5 LACL-PAGPRVYFLKGGYETFYSEYPECC---------VDVKPI----------------
: : : .:.:.::. : .: :. : .. :.
NP_001 LQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGS
110 120 130 140 150 160
150 160 170 180 190 200
pF1KB5 --SQEKIESERALISQCGKPVVNVSYRPAYDQGG-PVEILPFLYLGSAYHASKCEFLANL
:. . :..: .: :: ... :. ... ::.::: :::::: ... : ::.:
NP_001 DCSDAESEADRDSMS-CGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKL
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB5 HITALLNVSRRTSEACMTH--LHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLV
: .:::. . . .::: ::. : . ..: : :::.::: . .. :::
NP_001 GIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLV
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB5 HCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPST
:: ::.::: :. .::::. .. :..:.: .:...: .::::.::::::..: .
NP_001 HCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEE
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB5 PNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATA
. : . :.:...: . : .: .::. :
NP_001 RHSQEQGSGGQASAASNPPSFFT-TPTSDGAFELAPT
350 360 370 380
pF1KB5 TSC
>>XP_011529426 (OMIM: 300134) PREDICTED: dual specificit (384 aa)
initn: 538 init1: 315 opt: 424 Z-score: 410.7 bits: 84.7 E(85289): 3.9e-16
Smith-Waterman score: 545; 33.0% identity (57.1% similar) in 382 aa overlap (15-357:11-383)
10 20 30 40 50
pF1KB5 MKVTSLDGRQLRKMLRKEAAA---RCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARG
::.: . : ..:::: . .. . :.:.: : ...::: :
XP_011 MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 GAVSARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLR-----EESAARVVLTPL
:..:.: .:: :: : :.. :::. . .. . :: :. :: :
XP_011 GSLSVRALLPGPP-----LQPPPP--APVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTL
60 70 80 90 100
120 130 140
pF1KB5 LACL-PAGPRVYFLKGGYETFYSEYPECC---------VDVKPI----------------
: : : .:.:.::. : .: :. : .. :.
XP_011 LQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGS
110 120 130 140 150 160
150 160 170 180 190 200
pF1KB5 --SQEKIESERALISQCGKPVVNVSYRPAYDQGG-PVEILPFLYLGSAYHASKCEFLANL
:. . :..: .: :: ... :. ... ::.::: :::::: ... : ::.:
XP_011 DCSDAESEADRDSMS-CGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKL
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB5 HITALLNVSRRTSEACMTH--LHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLV
: .:::. . . .::: ::. : . ..: : :::.::: . .. :::
XP_011 GIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLV
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB5 HCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPST
:: ::.::: :. .::::. .. :..:.: .:...: .::::.::::::..: .
XP_011 HCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEE
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB5 PNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATA
. : . :.:...: . : .: .::. :
XP_011 RHSQEQGSGGQASAASNPPSFFT-TPTSDGAFELAPT
350 360 370 380
pF1KB5 TSC
384 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:11:36 2016 done: Sat Nov 5 02:11:38 2016
Total Scan time: 8.880 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]