Result of FASTA (omim) for
pFN21AB7230
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7230, 351 aa
1>>>pF1KB7230 351 - 351 aa - 351 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0991+/-0.000513; mu= 17.8037+/- 0.032
mean_var=110.3706+/-27.729, 0's: 0 Z-trim(109.5): 565 B-trim: 2073 in 2/49
Lambda= 0.122081
statistics sampled from 16952 (17752) to 16952 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.544), E-opt: 0.2 (0.208), width: 16
Scan time: 6.790
The best scores are: opt bits E(85289)
NP_001028252 (OMIM: 604849) trace amine-associated ( 351) 2393 433.1 4.5e-121
NP_055441 (OMIM: 604849) trace amine-associated re ( 306) 2092 380.0 3.8e-105
NP_003958 (OMIM: 607405) trace amine-associated re ( 337) 973 183.0 8.5e-46
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 894 169.1 1.3e-41
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 886 167.7 3.5e-41
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 851 161.5 2.5e-39
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 755 144.6 3.1e-34
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 519 103.0 1e-21
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 519 103.0 1e-21
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 519 103.1 1.1e-21
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 519 103.1 1.1e-21
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 519 103.1 1.1e-21
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 519 103.1 1.1e-21
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 519 103.1 1.1e-21
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 519 103.1 1.1e-21
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 420 85.6 1.9e-16
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 420 85.6 1.9e-16
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 420 85.6 2e-16
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 420 85.7 2e-16
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 420 85.7 2e-16
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 420 85.7 2e-16
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 420 85.7 2e-16
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 420 85.7 2e-16
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 420 85.7 2e-16
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 420 85.7 2.1e-16
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 420 85.8 2.2e-16
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 420 85.8 2.2e-16
NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 375 77.6 4.2e-14
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 374 77.5 5.3e-14
XP_011518927 (OMIM: 602927) PREDICTED: probable G- ( 415) 373 77.4 6.3e-14
XP_016874705 (OMIM: 602927) PREDICTED: probable G- ( 415) 373 77.4 6.3e-14
XP_016874702 (OMIM: 602927) PREDICTED: probable G- ( 434) 373 77.4 6.4e-14
XP_016874703 (OMIM: 602927) PREDICTED: probable G- ( 434) 373 77.4 6.4e-14
XP_016874701 (OMIM: 602927) PREDICTED: probable G- ( 434) 373 77.4 6.4e-14
XP_011518925 (OMIM: 602927) PREDICTED: probable G- ( 434) 373 77.4 6.4e-14
XP_016874704 (OMIM: 602927) PREDICTED: probable G- ( 434) 373 77.4 6.4e-14
XP_011518926 (OMIM: 602927) PREDICTED: probable G- ( 434) 373 77.4 6.4e-14
NP_006134 (OMIM: 602927) probable G-protein couple ( 415) 372 77.2 7.1e-14
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 368 76.5 1.1e-13
NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 366 76.0 1.2e-13
XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 366 76.0 1.2e-13
NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 366 76.0 1.2e-13
NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 366 76.0 1.2e-13
NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 366 76.0 1.2e-13
NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 366 76.0 1.2e-13
XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 366 76.1 1.3e-13
XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 366 76.1 1.3e-13
XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 366 76.1 1.3e-13
XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 366 76.1 1.3e-13
XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 366 76.1 1.3e-13
>>NP_001028252 (OMIM: 604849) trace amine-associated rec (351 aa)
initn: 2393 init1: 2393 opt: 2393 Z-score: 2294.6 bits: 433.1 E(85289): 4.5e-121
Smith-Waterman score: 2393; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
310 320 330 340 350
>>NP_055441 (OMIM: 604849) trace amine-associated recept (306 aa)
initn: 2092 init1: 2092 opt: 2092 Z-score: 2008.8 bits: 380.0 E(85289): 3.8e-105
Smith-Waterman score: 2092; 100.0% identity (100.0% similar) in 306 aa overlap (46-351:1-306)
20 30 40 50 60 70
pF1KB7 TQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLH
::::::::::::::::::::::::::::::
NP_055 MYSFMAGSIFITIFGNLAMIISISYFKQLH
10 20 30
80 90 100 110 120 130
pF1KB7 TPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLC
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 SVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB7 ACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVK
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB7 KDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIY
220 230 240 250 260 270
320 330 340 350
pF1KB7 GFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
::::::::::::::::::::::::::::::::::::
NP_055 GFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
280 290 300
>>NP_003958 (OMIM: 607405) trace amine-associated recept (337 aa)
initn: 976 init1: 566 opt: 973 Z-score: 943.2 bits: 183.0 E(85289): 8.5e-46
Smith-Waterman score: 973; 43.3% identity (75.6% similar) in 307 aa overlap (30-336:21-326)
10 20 30 40 50 60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
: :::.. ..::.....: :....: ..:
NP_003 MRAVFIQGAEEHPAAFCYQVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
:. . ...:::: ::::::::.::.:..:..::. ..: : :::::.::.:: .:...
NP_003 NVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
.: .. .::::::: ..::: ::: :::: .:.:. : : .: :.::.:.. ..
NP_003 YLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
... . . . : .:: ...::.:: : ::.: .:...: :::.:. ..:
NP_003 TDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNF-PLFFVPCLIMISLYVKIFVVATRQA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL
. :..: .. . .:...::::::::..:..::::.: . ..: .:.: :: ..:: .
NP_003 QQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIF
240 250 260 270 280 290
310 320 330 340 350
pF1KB7 TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
::.::::.:::.:: : : :::.::: : :.::
NP_003 IWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
300 310 320 330
>>NP_778237 (OMIM: 608923) trace amine-associated recept (345 aa)
initn: 867 init1: 500 opt: 894 Z-score: 867.9 bits: 169.1 E(85289): 1.3e-41
Smith-Waterman score: 894; 39.6% identity (70.1% similar) in 321 aa overlap (25-337:14-333)
10 20 30 40 50 60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
: : :: . : : :: .: .. . ...::
NP_778 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFG
10 20 30 40
70 80 90 100 110 120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
:: ..::: .:::::.:::::. :.: .:::.: :.::.::.:.::.::::: .:: ..
NP_778 NLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
:. . .:.:::: ..:::. :. ::.: ::.:. : . . : .: .. .: .
NP_778 CCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
. .: ::.: . . : ..: .. :. : : :.. :: : .:. .::.:: :.:..:
NP_778 TGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLS-FFIPTFIMIILYGNIFLVARRQA
170 180 190 200 210 220
250 260 270 280 290
pF1KB7 HAINNL-------RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST
. :.: :. . .: ....:::::::... .:.. :.: . :.: :..: :
NP_778 KKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFIT
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 PVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
:. ... : .:.::. :::::..::::::.:.: :. :.....
NP_778 PACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
290 300 310 320 330 340
>>NP_778227 (OMIM: 608282) trace amine-associated recept (348 aa)
initn: 882 init1: 551 opt: 886 Z-score: 860.2 bits: 167.7 E(85289): 3.5e-41
Smith-Waterman score: 886; 40.2% identity (70.1% similar) in 321 aa overlap (25-337:14-333)
10 20 30 40 50 60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
: . :.:: .. : : : .:. .. . .. ::
NP_778 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFG
10 20 30 40
70 80 90 100 110 120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
:: ..:.: .:::::::::::: :.: .:::.: :.::.: .::::.::::: ..::..
NP_778 NLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
:: . ..:.:::: ...::. :. :: : ::.:. : ..: : ...:.. .
NP_778 CFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
. : .::: . ..: ..: . .:. : :. :: :. :: ::.::: :....:
NP_778 TGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQA
170 180 190 200 210 220
250 260 270 280 290
pF1KB7 HAINNL-------RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST
. :.. :. ...: :...::::::::....::. :.: . ..: ..:: :
NP_778 RKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFIT
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 PVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
: ... :.: :.::. :::::.::: :: .:.: :. ::.. .
NP_778 PPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
290 300 310 320 330 340
>>NP_444508 (OMIM: 606927) trace amine-associated recept (342 aa)
initn: 846 init1: 516 opt: 851 Z-score: 827.0 bits: 161.5 E(85289): 2.5e-39
Smith-Waterman score: 851; 38.5% identity (68.6% similar) in 322 aa overlap (25-337:13-332)
10 20 30 40 50
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYS-FMAGSIFITIF
: : : :: :. : : :: .:. : ::. ...:
NP_444 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSL-LAVF
10 20 30 40
60 70 80 90 100 110
pF1KB7 GNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIY
::: .. :. .:::::.:::::: :.: .:::.: :.: .::.:.::.::::: :: ..
NP_444 GNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLH
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 YSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVV
:. . .:..::: . :::. .. ::.:.::.:. : . . : .: ... .:
NP_444 SCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 FSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKH
.. . ::.: . : ..: .. .. : :. :: : .:. .:.::: .....
NP_444 YTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 A-------HAINNLRENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFS
: ... :. . .: :...:::::::... .:.. :.: ::.: :..:
NP_444 AIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 TPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
::. ... : .:.::. :::::..::::::.:.: :: : ....
NP_444 TPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
290 300 310 320 330 340
>>NP_612200 (OMIM: 609333) trace amine-associated recept (339 aa)
initn: 1065 init1: 610 opt: 755 Z-score: 735.7 bits: 144.6 E(85289): 3.1e-34
Smith-Waterman score: 1111; 50.6% identity (76.7% similar) in 322 aa overlap (25-335:5-324)
10 20 30 40 50 60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
: . : :: .:. : ::...::.:. :. :. :
NP_612 MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVG
10 20 30 40
70 80 90 100 110 120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
:: .:.:::.:::::::::.:: ::: .::::: .:::::.::.:.::::: .::::.
NP_612 NLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
: :.::: .::::: ..:::.::.: :: :..:..: :: .... ::::..::::..:
NP_612 STDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIF
110 120 130 140 150 160
190 200 210 220 230
pF1KB7 SEAYADGIEG-YDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKH
: : : : : : ..: :.:.:. :. ::..:. :::.:. .: .:. .....
NP_612 LELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQ
170 180 190 200 210 220
240 250 260 270 280
pF1KB7 AHAINNLRENQNNQV----------KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLN
:. :.. ::. :. .:..::.::::::.::::.:: : :. ..::::.
NP_612 ARLISD--ANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLH
230 240 250 260 270
290 300 310 320 330 340
pF1KB7 FSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKE
. : .: :.: ::::.::: ::..:.:::::::.:::..:.::::
NP_612 YIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELS
280 290 300 310 320 330
350
pF1KB7 SE
NP_612 S
>>NP_071640 (OMIM: 142703) histamine H2 receptor isoform (359 aa)
initn: 416 init1: 272 opt: 519 Z-score: 510.8 bits: 103.0 E(85289): 1e-21
Smith-Waterman score: 519; 30.5% identity (63.3% similar) in 311 aa overlap (39-344:14-317)
10 20 30 40 50 60
pF1KB7 ELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISI
: . .... .: :.::. ::... ...
NP_071 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAV
10 20 30 40
70 80 90 100 110 120
pF1KB7 SYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSI
. ..:.. :: .:.:.::::.:::. ..:.: : .. : :: .::.:: :.:.::
NP_071 GLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 TSIFHLCSVAIDRFYAICYPLLYSTKITIPV-IKRLLLLCWSVPGAFAFGVVFS--EAYA
.::..: ...::. :. :: : . .: :: . :.: : . ...: . ..
NP_071 ASILNLFMISLDRYCAVMDPLRYPVLVT-PVRVAISLVLIWVISITLSFLSIHLGWNSRN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 DGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINN
. .: .:.: :. :...: . .. :. : .: : .:: :.: .:. ::.
NP_071 ETSKGNHT----TSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH
170 180 190 200 210
250 260 270 280 290 300
pF1KB7 LRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPV--VLFDALTWF
. . .. ..::. ::. :.:.:..:::: .:: .. : . . :: . :.
NP_071 ISSWKAATIR-EHKATVTLAAVMGAFIICWFP-YFTAFVYRGLRGDDAINEVLEAIVLWL
220 230 240 250 260 270
310 320 330 340 350
pF1KB7 GYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
:: ::. ::..:. . :: . . .. .. . :.: :
NP_071 GYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQE
280 290 300 310 320 330
NP_071 EKPLKLQVWSGTEVTAPQGATDR
340 350
>>XP_006714928 (OMIM: 142703) PREDICTED: histamine H2 re (362 aa)
initn: 416 init1: 272 opt: 519 Z-score: 510.7 bits: 103.0 E(85289): 1e-21
Smith-Waterman score: 519; 30.5% identity (63.3% similar) in 311 aa overlap (39-344:14-317)
10 20 30 40 50 60
pF1KB7 ELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISI
: . .... .: :.::. ::... ...
XP_006 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAV
10 20 30 40
70 80 90 100 110 120
pF1KB7 SYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSI
. ..:.. :: .:.:.::::.:::. ..:.: : .. : :: .::.:: :.:.::
XP_006 GLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 TSIFHLCSVAIDRFYAICYPLLYSTKITIPV-IKRLLLLCWSVPGAFAFGVVFS--EAYA
.::..: ...::. :. :: : . .: :: . :.: : . ...: . ..
XP_006 ASILNLFMISLDRYCAVMDPLRYPVLVT-PVRVAISLVLIWVISITLSFLSIHLGWNSRN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 DGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINN
. .: .:.: :. :...: . .. :. : .: : .:: :.: .:. ::.
XP_006 ETSKGNHT----TSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH
170 180 190 200 210
250 260 270 280 290 300
pF1KB7 LRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPV--VLFDALTWF
. . .. ..::. ::. :.:.:..:::: .:: .. : . . :: . :.
XP_006 ISSWKAATIR-EHKATVTLAAVMGAFIICWFP-YFTAFVYRGLRGDDAINEVLEAIVLWL
220 230 240 250 260 270
310 320 330 340 350
pF1KB7 GYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
:: ::. ::..:. . :: . . .. .. . :.: :
XP_006 GYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQE
280 290 300 310 320 330
XP_006 EKPLKLQVWSGTEVTAPQGATDRNSS
340 350 360
>>NP_001124527 (OMIM: 142703) histamine H2 receptor isof (397 aa)
initn: 416 init1: 272 opt: 519 Z-score: 510.3 bits: 103.1 E(85289): 1.1e-21
Smith-Waterman score: 519; 30.5% identity (63.3% similar) in 311 aa overlap (39-344:14-317)
10 20 30 40 50 60
pF1KB7 ELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISI
: . .... .: :.::. ::... ...
NP_001 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAV
10 20 30 40
70 80 90 100 110 120
pF1KB7 SYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSI
. ..:.. :: .:.:.::::.:::. ..:.: : .. : :: .::.:: :.:.::
NP_001 GLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 TSIFHLCSVAIDRFYAICYPLLYSTKITIPV-IKRLLLLCWSVPGAFAFGVVFS--EAYA
.::..: ...::. :. :: : . .: :: . :.: : . ...: . ..
NP_001 ASILNLFMISLDRYCAVMDPLRYPVLVT-PVRVAISLVLIWVISITLSFLSIHLGWNSRN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 DGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINN
. .: .:.: :. :...: . .. :. : .: : .:: :.: .:. ::.
NP_001 ETSKGNHT----TSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH
170 180 190 200 210
250 260 270 280 290 300
pF1KB7 LRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPV--VLFDALTWF
. . .. ..::. ::. :.:.:..:::: .:: .. : . . :: . :.
NP_001 ISSWKAATIR-EHKATVTLAAVMGAFIICWFP-YFTAFVYRGLRGDDAINEVLEAIVLWL
220 230 240 250 260 270
310 320 330 340 350
pF1KB7 GYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
:: ::. ::..:. . :: . . .. .. . :.: :
NP_001 GYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQE
280 290 300 310 320 330
NP_001 EKPLKLQVWSGTEVTAPQGATDRPWLCLPECWSVELTHSFIHLFIHSFANIHPIPTTCQE
340 350 360 370 380 390
351 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:23:45 2016 done: Fri Nov 4 20:23:46 2016
Total Scan time: 6.790 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]