Result of FASTA (omim) for
pFN21AB6564
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6564, 400 aa
1>>>pF1KB6564 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1633+/-0.000466; mu= 0.8321+/- 0.028
mean_var=559.8048+/-124.610, 0's: 0 Z-trim(120.7): 1419 B-trim: 33 in 1/54
Lambda= 0.054207
statistics sampled from 33957 (36228) to 33957 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.425), width: 16
Scan time: 8.710
The best scores are: opt bits E(85289)
NP_109587 (OMIM: 601263,615280) dual specificity m ( 400) 2665 223.4 7.6e-58
XP_016882478 (OMIM: 601263,615280) PREDICTED: dual ( 512) 2315 196.2 1.5e-49
NP_002746 (OMIM: 163950,176872,615279) dual specif ( 393) 2130 181.6 3e-45
XP_011520085 (OMIM: 163950,176872,615279) PREDICTE ( 371) 2099 179.1 1.5e-44
XP_016882480 (OMIM: 601263,615280) PREDICTED: dual ( 252) 1530 134.3 3.2e-31
XP_006722862 (OMIM: 601263,615280) PREDICTED: dual ( 307) 1528 134.3 3.9e-31
XP_016882479 (OMIM: 601263,615280) PREDICTED: dual ( 419) 1528 134.5 4.6e-31
XP_016877902 (OMIM: 163950,176872,615279) PREDICTE ( 217) 1135 103.3 5.9e-22
NP_001193733 (OMIM: 602520) dual specificity mitog ( 412) 781 76.1 1.7e-13
NP_660143 (OMIM: 602520) dual specificity mitogen- ( 448) 781 76.2 1.8e-13
NP_002748 (OMIM: 602520) dual specificity mitogen- ( 438) 760 74.5 5.6e-13
XP_016877900 (OMIM: 163950,176872,615279) PREDICTE ( 367) 753 73.8 7.5e-13
XP_016877901 (OMIM: 163950,176872,615279) PREDICTE ( 345) 722 71.4 3.9e-12
NP_002749 (OMIM: 601254) dual specificity mitogen- ( 334) 640 64.9 3.3e-10
XP_011523328 (OMIM: 601254) PREDICTED: dual specif ( 337) 640 64.9 3.3e-10
XP_011523327 (OMIM: 601254) PREDICTED: dual specif ( 345) 640 64.9 3.3e-10
XP_016880347 (OMIM: 602315) PREDICTED: dual specif ( 318) 620 63.3 9.4e-10
XP_005256780 (OMIM: 602315) PREDICTED: dual specif ( 318) 620 63.3 9.4e-10
XP_011522261 (OMIM: 602315) PREDICTED: dual specif ( 318) 620 63.3 9.4e-10
XP_016880348 (OMIM: 602315) PREDICTED: dual specif ( 318) 620 63.3 9.4e-10
NP_001303261 (OMIM: 602315) dual specificity mitog ( 318) 620 63.3 9.4e-10
NP_002747 (OMIM: 602315) dual specificity mitogen- ( 318) 620 63.3 9.4e-10
XP_016880346 (OMIM: 602315) PREDICTED: dual specif ( 343) 620 63.4 9.8e-10
NP_659731 (OMIM: 602315) dual specificity mitogen- ( 347) 620 63.4 9.9e-10
NP_003001 (OMIM: 601335) dual specificity mitogen- ( 399) 612 62.9 1.6e-09
NP_001268364 (OMIM: 601335) dual specificity mitog ( 410) 612 62.9 1.7e-09
XP_011523329 (OMIM: 601254) PREDICTED: dual specif ( 278) 606 62.1 1.9e-09
XP_005257573 (OMIM: 601254) PREDICTED: dual specif ( 278) 606 62.1 1.9e-09
NP_001317379 (OMIM: 601254) dual specificity mitog ( 278) 606 62.1 1.9e-09
XP_006722038 (OMIM: 601254) PREDICTED: dual specif ( 278) 606 62.1 1.9e-09
XP_011522260 (OMIM: 602315) PREDICTED: dual specif ( 298) 597 61.5 3.2e-09
NP_660186 (OMIM: 603014) dual specificity mitogen- ( 419) 579 60.3 1e-08
NP_001284484 (OMIM: 603014) dual specificity mitog ( 435) 579 60.3 1e-08
XP_005256810 (OMIM: 601335) PREDICTED: dual specif ( 281) 567 59.1 1.6e-08
XP_011522278 (OMIM: 601335) PREDICTED: dual specif ( 319) 565 59.0 1.9e-08
NP_001284485 (OMIM: 603014) dual specificity mitog ( 426) 543 57.5 7.1e-08
XP_006722863 (OMIM: 603014) PREDICTED: dual specif ( 442) 543 57.5 7.2e-08
XP_011522279 (OMIM: 601335) PREDICTED: dual specif ( 253) 513 54.8 2.8e-07
XP_005256812 (OMIM: 601335) PREDICTED: dual specif ( 253) 513 54.8 2.8e-07
XP_016883522 (OMIM: 604965,614868) PREDICTED: seri ( 388) 508 54.7 4.5e-07
XP_016869247 (OMIM: 605030) PREDICTED: serine/thre ( 456) 508 54.8 4.9e-07
XP_005260590 (OMIM: 604965,614868) PREDICTED: seri ( 462) 508 54.8 4.9e-07
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519) 509 55.0 4.9e-07
XP_016869246 (OMIM: 605030) PREDICTED: serine/thre ( 524) 509 55.0 5e-07
NP_006273 (OMIM: 604965,614868) serine/threonine-p ( 487) 508 54.9 5.1e-07
NP_006272 (OMIM: 605030) serine/threonine-protein ( 491) 508 54.9 5.1e-07
XP_011515550 (OMIM: 605030) PREDICTED: serine/thre ( 576) 509 55.1 5.2e-07
XP_016869245 (OMIM: 605030) PREDICTED: serine/thre ( 580) 509 55.1 5.2e-07
XP_011515553 (OMIM: 605030) PREDICTED: serine/thre ( 522) 508 54.9 5.2e-07
XP_011527322 (OMIM: 604965,614868) PREDICTED: seri ( 404) 501 54.2 6.7e-07
>>NP_109587 (OMIM: 601263,615280) dual specificity mitog (400 aa)
initn: 2665 init1: 2665 opt: 2665 Z-score: 1159.5 bits: 223.4 E(85289): 7.6e-58
Smith-Waterman score: 2665; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_109 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
310 320 330 340 350 360
370 380 390 400
pF1KB6 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
::::::::::::::::::::::::::::::::::::::::
NP_109 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
370 380 390 400
>>XP_016882478 (OMIM: 601263,615280) PREDICTED: dual spe (512 aa)
initn: 2315 init1: 2315 opt: 2315 Z-score: 1010.6 bits: 196.2 E(85289): 1.5e-49
Smith-Waterman score: 2315; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKWFWEGRQPHSIL
310 320 330 340 350 360
370 380 390 400
pF1KB6 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
XP_016 LPPSTQQHLWRGLHRHVPQTTGKELRTPRCPQGRSMCVSSGRRGTAPHSWCRSCPGPLAC
370 380 390 400 410 420
>>NP_002746 (OMIM: 163950,176872,615279) dual specificit (393 aa)
initn: 2120 init1: 1539 opt: 2130 Z-score: 933.4 bits: 181.6 E(85289): 3e-45
Smith-Waterman score: 2130; 80.4% identity (92.0% similar) in 398 aa overlap (2-399:1-391)
10 20 30 40 50 60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
. ..::. : . .::. .: . .. ...:.:: ::::::::::::::.:::::::::
NP_002 MPKKKPT-P-IQLNPA-PDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
: :::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::
NP_002 KQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
::::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..:
NP_002 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
:.::::::.:::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_002 LTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
:::::::::::::::::::.:::::::::::::::: .:: : ::. ::::
NP_002 GTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQV----EGDAAETPPRPRT
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB6 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
::::.:..:::::: :::::::::::::::::::.:::. .::.::::::::::::::::
NP_002 PGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADL
300 310 320 330 340 350
370 380 390 400
pF1KB6 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
:.: :.:::::..::::::::::.:. ::::.:::..:
NP_002 KQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
360 370 380 390
>>XP_011520085 (OMIM: 163950,176872,615279) PREDICTED: d (371 aa)
initn: 2106 init1: 1525 opt: 2099 Z-score: 920.6 bits: 179.1 E(85289): 1.5e-44
Smith-Waterman score: 2099; 85.3% identity (93.7% similar) in 367 aa overlap (33-399:7-369)
10 20 30 40 50 60
pF1KB6 ARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKA
:: ::::::::::::::.::::::::::
XP_011 MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQ
10 20 30
70 80 90 100 110 120
pF1KB6 KVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVL
:::::::::::.:::::::::::: ::.:.::::.:::::::::::::::::::::::::
XP_011 KVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 HECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLA
::::::::::::::::::::::::::::::::::::::.: ::::.:::::::::..::.
XP_011 HECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLT
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB6 YLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGT
::::::.:::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 YLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 HYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPG
:::::::::::::::::.:::::::::::::::: .:: : ::. :::: ::
XP_011 HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQV----EGDAAETPPRPRTPG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 RPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKM
::.:..:::::: :::::::::::::::::::.:::. .::.:::::::::::::::::.
XP_011 RPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQ
280 290 300 310 320 330
370 380 390 400
pF1KB6 LTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
: :.:::::..::::::::::.:. ::::.:::..:
XP_011 LMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
340 350 360 370
>>XP_016882480 (OMIM: 601263,615280) PREDICTED: dual spe (252 aa)
initn: 1518 init1: 1518 opt: 1530 Z-score: 681.6 bits: 134.3 E(85289): 3.2e-31
Smith-Waterman score: 1530; 94.8% identity (96.0% similar) in 252 aa overlap (1-252:1-250)
10 20 30 40 50 60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::: .
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMA--ETT
190 200 210 220 230
250 260 270 280 290 300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
: . : . ::
XP_016 GDSATCQIEPWSSL
240 250
>>XP_006722862 (OMIM: 601263,615280) PREDICTED: dual spe (307 aa)
initn: 1528 init1: 1528 opt: 1528 Z-score: 680.0 bits: 134.3 E(85289): 3.9e-31
Smith-Waterman score: 1821; 76.8% identity (76.8% similar) in 400 aa overlap (1-400:1-307)
10 20 30 40 50 60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAP----
190 200 210 220 230
250 260 270 280 290 300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
XP_006 ------------------------------------------------------------
310 320 330 340 350 360
pF1KB6 PGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADL
:::::::::::::::::::::::::::::::
XP_006 -----------------------------PPKLPNGVFTPDFQEFVNKCLIKNPAERADL
240 250 260
370 380 390 400
pF1KB6 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
::::::::::::::::::::::::::::::::::::::::
XP_006 KMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
270 280 290 300
>>XP_016882479 (OMIM: 601263,615280) PREDICTED: dual spe (419 aa)
initn: 1561 init1: 1528 opt: 1528 Z-score: 678.8 bits: 134.5 E(85289): 4.6e-31
Smith-Waterman score: 1528; 100.0% identity (100.0% similar) in 236 aa overlap (1-236:1-236)
10 20 30 40 50 60
pF1KB6 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPPPKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRP
XP_016 PNGVFTPDFQEFVNKWFWEGRQPHSILLPPSTQQHLWRGLHRHVPQTTGKELRTPRCPQG
250 260 270 280 290 300
>>XP_016877902 (OMIM: 163950,176872,615279) PREDICTED: d (217 aa)
initn: 1142 init1: 595 opt: 1135 Z-score: 515.2 bits: 103.3 E(85289): 5.9e-22
Smith-Waterman score: 1135; 80.3% identity (91.3% similar) in 208 aa overlap (192-399:12-215)
170 180 190 200 210 220
pF1KB6 AKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLID
...:::::::::::::::::::::::::::
XP_016 MVPVHQQFLSKQHNVKPSNILVNSRGEIKLCDFGVSGQLID
10 20 30 40
230 240 250 260 270 280
pF1KB6 SMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGR
:::::::::::::.::::::::::::::::::::::::.:::::::::::::::: .::
XP_016 SMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC
50 60 70 80 90 100
290 300 310 320 330 340
pF1KB6 PVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPD
: ::. :::: ::::.:..:::::: :::::::::::::::::::.:::. .
XP_016 QV----EGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLE
110 120 130 140 150
350 360 370 380 390 400
pF1KB6 FQEFVNKCLIKNPAERADLKMLTNHTFIKRSEVEEVDFAGWLCKTLRLNQPGTPTRTAV
::.:::::::::::::::::.: :.:::::..::::::::::.:. ::::.:::..:
XP_016 FQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
160 170 180 190 200 210
>>NP_001193733 (OMIM: 602520) dual specificity mitogen-a (412 aa)
initn: 712 init1: 388 opt: 781 Z-score: 363.1 bits: 76.1 E(85289): 1.7e-13
Smith-Waterman score: 863; 40.6% identity (68.3% similar) in 347 aa overlap (52-395:110-412)
30 40 50 60 70 80
pF1KB6 PSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAG
:. : : . :.....:.. . :: :
NP_001 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB6 NGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
:::.: :. : ::: :.: :.: :.: ...::. ::..:..:.: ::.::::::. ..
NP_001 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB6 EISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNIL
.:::: : ::::::: ...::..::....::..::.:: . .:.::::::::.:
NP_001 RISICTEFMDGGSLDVY----RKMPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB6 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELA
::.::..:::::::: ::..:.:...::: .::::::..: .:...::.::.:.:..:::
NP_001 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB6 VGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFEL
.::.: : .. ..: :. : ..:
NP_001 LGRFPYPQ--------------IQKNQG---SLMP----------------------LQL
320 330
330 340 350 360 370 380
pF1KB6 LDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFI-KRSEVEEVDFA
:. ::.: : :: : :. : .:...:. :.: :: . : .: :: . .. . . .
NP_001 LQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVS
340 350 360 370 380 390
390 400
pF1KB6 GWLCKTL--RLNQPGTPTRTAV
:.:..: : .: : :
NP_001 MWVCRALEERRSQQGPP
400 410
>>NP_660143 (OMIM: 602520) dual specificity mitogen-acti (448 aa)
initn: 712 init1: 388 opt: 781 Z-score: 362.8 bits: 76.2 E(85289): 1.8e-13
Smith-Waterman score: 863; 40.6% identity (68.3% similar) in 347 aa overlap (52-395:146-448)
30 40 50 60 70 80
pF1KB6 PSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAG
:. : : . :.....:.. . :: :
NP_660 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
120 130 140 150 160 170
90 100 110 120 130 140
pF1KB6 NGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
:::.: :. : ::: :.: :.: :.: ...::. ::..:..:.: ::.::::::. ..
NP_660 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
180 190 200 210 220 230
150 160 170 180 190 200
pF1KB6 EISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNIL
.:::: : ::::::: ...::..::....::..::.:: . .:.::::::::.:
NP_660 RISICTEFMDGGSLDVY----RKMPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
240 250 260 270 280 290
210 220 230 240 250 260
pF1KB6 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMAPERLQGTHYSVQSDIWSMGLSLVELA
::.::..:::::::: ::..:.:...::: .::::::..: .:...::.::.:.:..:::
NP_660 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA
300 310 320 330 340 350
270 280 290 300 310 320
pF1KB6 VGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPAMAIFEL
.::.: : .. ..: :. : ..:
NP_660 LGRFPYPQ--------------IQKNQG---SLMP----------------------LQL
360 370
330 340 350 360 370 380
pF1KB6 LDYIVNEPPPKLPNGVFTPDFQEFVNKCLIKNPAERADLKMLTNHTFI-KRSEVEEVDFA
:. ::.: : :: : :. : .:...:. :.: :: . : .: :: . .. . . .
NP_660 LQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVS
380 390 400 410 420 430
390 400
pF1KB6 GWLCKTL--RLNQPGTPTRTAV
:.:..: : .: : :
NP_660 MWVCRALEERRSQQGPP
440
400 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:07:30 2016 done: Sat Nov 5 01:07:32 2016
Total Scan time: 8.710 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]