Result of FASTA (omim) for
pFN21AB8996
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8996, 407 aa
1>>>pF1KB8996 407 - 407 aa - 407 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0815+/-0.000325; mu= 2.7357+/- 0.021
mean_var=243.5797+/-50.278, 0's: 0 Z-trim(123.8): 59 B-trim: 1426 in 1/59
Lambda= 0.082178
statistics sampled from 44312 (44374) to 44312 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.52), width: 16
Scan time: 6.490
The best scores are: opt bits E(85289)
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 2859 351.3 2.5e-96
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 700 95.3 3e-19
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 700 95.3 3e-19
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 700 95.4 3.3e-19
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 700 95.4 3.6e-19
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 623 86.1 1.4e-16
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 552 77.7 4.9e-14
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 347 53.3 7.7e-07
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 350 53.8 8.2e-07
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 347 53.4 1.1e-06
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 328 51.1 4.8e-06
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 328 51.1 4.8e-06
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 328 51.2 5.1e-06
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 328 51.2 5.4e-06
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 328 51.2 5.4e-06
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 328 51.2 5.4e-06
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 328 51.2 5.4e-06
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 316 49.8 1.5e-05
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 312 49.4 2.4e-05
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 307 48.8 3.4e-05
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 298 47.5 4.3e-05
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 300 47.9 5.9e-05
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 298 47.7 6.9e-05
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 296 47.4 8.1e-05
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 293 47.1 9.6e-05
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 293 47.1 0.0001
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 292 47.0 0.00012
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 287 46.4 0.00016
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 284 46.1 0.00024
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 284 46.1 0.00024
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 284 46.1 0.00024
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 268 43.9 0.00047
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 268 44.0 0.00067
NP_003230 (OMIM: 107970,190230,615582) transformin ( 412) 264 43.6 0.0011
NP_001316868 (OMIM: 107970,190230,615582) transfor ( 412) 264 43.6 0.0011
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390) 261 43.2 0.0013
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391) 261 43.2 0.0013
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 246 41.5 0.0048
NP_003229 (OMIM: 190220,614816) transforming growt ( 414) 238 40.5 0.009
NP_001129071 (OMIM: 190220,614816) transforming gr ( 442) 238 40.6 0.0094
>>NP_002184 (OMIM: 147390) inhibin beta B chain prepropr (407 aa)
initn: 2859 init1: 2859 opt: 2859 Z-score: 1850.2 bits: 351.3 E(85289): 2.5e-96
Smith-Waterman score: 2859; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB8 MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM
310 320 330 340 350 360
370 380 390 400
pF1KB8 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
:::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
370 380 390 400
>>NP_002183 (OMIM: 147290) inhibin beta A chain prepropr (426 aa)
initn: 1151 init1: 437 opt: 700 Z-score: 466.6 bits: 95.3 E(85289): 3e-19
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:22-426)
20 30 40 50 60 70
pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
: ::: : : : ::. :... .
NP_002 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
10 20 30 40 50
80 90 100 110 120 130
pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
...::::.:::. :... ::..:. :::::...:.::::.::: :.: ::: :. .
NP_002 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
. .:..::::.:::. ...: :.: ::.::.. : .: .::.::. : :
NP_002 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
120 130 140 150 160
200 210 220 230
pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
..: ...: . ::.: : :.: ... :: :: ..: ::.::.
NP_002 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
170 180 190 200 210 220
240 250 260
pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
. .:: :...:. :.. . :..::: .. :.. . ::
NP_002 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
.:::::...::: . : :: :.:::::::..:.::..:::..:. ::::::::::.
NP_002 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.:::: :::::
NP_002 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
350 360 370 380 390 400
390 400
pF1KB8 FDDEYNIVKRDVPNMIVEECGCA
.:: ::.:.:. :::::::::.
NP_002 YDDGQNIIKKDIQNMIVEECGCS
410 420
>>XP_016867665 (OMIM: 147290) PREDICTED: inhibin beta A (426 aa)
initn: 1151 init1: 437 opt: 700 Z-score: 466.6 bits: 95.3 E(85289): 3e-19
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:22-426)
20 30 40 50 60 70
pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
: ::: : : : ::. :... .
XP_016 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
10 20 30 40 50
80 90 100 110 120 130
pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
...::::.:::. :... ::..:. :::::...:.::::.::: :.: ::: :. .
XP_016 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
. .:..::::.:::. ...: :.: ::.::.. : .: .::.::. : :
XP_016 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
120 130 140 150 160
200 210 220 230
pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
..: ...: . ::.: : :.: ... :: :: ..: ::.::.
XP_016 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
170 180 190 200 210 220
240 250 260
pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
. .:: :...:. :.. . :..::: .. :.. . ::
XP_016 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
.:::::...::: . : :: :.:::::::..:.::..:::..:. ::::::::::.
XP_016 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.:::: :::::
XP_016 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
350 360 370 380 390 400
390 400
pF1KB8 FDDEYNIVKRDVPNMIVEECGCA
.:: ::.:.:. :::::::::.
XP_016 YDDGQNIIKKDIQNMIVEECGCS
410 420
>>XP_016867664 (OMIM: 147290) PREDICTED: inhibin beta A (483 aa)
initn: 1151 init1: 437 opt: 700 Z-score: 465.9 bits: 95.4 E(85289): 3.3e-19
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:79-483)
20 30 40 50 60 70
pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
: ::: : : : ::. :... .
XP_016 AITTTFAARMPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
50 60 70 80 90 100
80 90 100 110 120 130
pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
...::::.:::. :... ::..:. :::::...:.::::.::: :.: ::: :. .
XP_016 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
110 120 130 140 150 160
140 150 160 170 180 190
pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
. .:..::::.:::. ...: :.: ::.::.. : .: .::.::. : :
XP_016 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
170 180 190 200 210 220
200 210 220 230
pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
..: ...: . ::.: : :.: ... :: :: ..: ::.::.
XP_016 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
230 240 250 260 270 280
240 250 260
pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
. .:: :...:. :.. . :..::: .. :.. . ::
XP_016 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
290 300 310 320 330 340
270 280 290 300 310 320
pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
.:::::...::: . : :: :.:::::::..:.::..:::..:. ::::::::::.
XP_016 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
350 360 370 380 390 400
330 340 350 360 370 380
pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.:::: :::::
XP_016 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
410 420 430 440 450 460
390 400
pF1KB8 FDDEYNIVKRDVPNMIVEECGCA
.:: ::.:.:. :::::::::.
XP_016 YDDGQNIIKKDIQNMIVEECGCS
470 480
>>XP_016867663 (OMIM: 147290) PREDICTED: inhibin beta A (548 aa)
initn: 1151 init1: 437 opt: 700 Z-score: 465.2 bits: 95.4 E(85289): 3.6e-19
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:144-548)
20 30 40 50 60 70
pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
: ::: : : : ::. :... .
XP_016 AITTTFAARMPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
120 130 140 150 160 170
80 90 100 110 120 130
pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
...::::.:::. :... ::..:. :::::...:.::::.::: :.: ::: :. .
XP_016 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
180 190 200 210 220 230
140 150 160 170 180 190
pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
. .:..::::.:::. ...: :.: ::.::.. : .: .::.::. : :
XP_016 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
240 250 260 270 280
200 210 220 230
pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
..: ...: . ::.: : :.: ... :: :: ..: ::.::.
XP_016 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
290 300 310 320 330 340
240 250 260
pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
. .:: :...:. :.. . :..::: .. :.. . ::
XP_016 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
350 360 370 380 390 400
270 280 290 300 310 320
pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
.:::::...::: . : :: :.:::::::..:.::..:::..:. ::::::::::.
XP_016 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
410 420 430 440 450 460
330 340 350 360 370 380
pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.:::: :::::
XP_016 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
470 480 490 500 510 520
390 400
pF1KB8 FDDEYNIVKRDVPNMIVEECGCA
.:: ::.:.:. :::::::::.
XP_016 YDDGQNIIKKDIQNMIVEECGCS
530 540
>>NP_005529 (OMIM: 601233) inhibin beta C chain prepropr (352 aa)
initn: 709 init1: 338 opt: 623 Z-score: 418.4 bits: 86.1 E(85289): 1.4e-16
Smith-Waterman score: 776; 38.3% identity (64.6% similar) in 373 aa overlap (42-407:14-352)
20 30 40 50 60
pF1KB8 ACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSP-GGSQDTCTSCGGFRRPE-ELGR
: ..: .:.: : .::: : ::
NP_005 MTSSLLLAFLLLAPTTVATPRAGGQ--CPACGG---PTLELES
10 20 30
70 80 90 100 110 120
pF1KB8 VDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGH
.:. .:: ::..:.. ::.... : .::. :::..::. .:.
NP_005 QRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALRTALQHLHG----------VPQ----
40 50 60 70 80
130 140 150 160 170 180
pF1KB8 ASPGADGQERVSEIISFAETDGLAS-SRVRLYF-FISNEGNQNLFVVQASLWLYLKLLPY
.. :..:. :::::::: ::.. ...:: : : :.. . : :::: ....: :
NP_005 GALLEDNREQECEIISFAET-GLSTINQTRLDFHFSSDRTAGDREVQQASLMFFVQL-PS
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB8 VLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRV-DLKRSGWHTFPLTEAIQALFERGERRL
. :::: : :. ... . . .. :::: .:: :: .:. :
NP_005 --NTTWTLKVRVLVL---GPHNTNLTLATQYLLEVDASGWHQLPLGPEAQAACSQGHLTL
150 160 170 180 190
250 260 270 280 290 300
pF1KB8 NLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQ
.: .. . : ... : .:::::....:.: ..:.:..::..:.: . .::::
NP_005 ELVLEGQVAQSSVIL------GGAAHRPFVAARVRVG-GKHQIHRRGIDCQGGSRMCCRQ
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB8 QFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPG
.::.::: :::.:::: : :: :.: :.:: ..::.:: :.::::::.: . . :
NP_005 EFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKA-NTAAG
260 270 280 290 300
370 380 390 400
pF1KB8 TVN--SCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
:.. :::.:: .:.::.: . :::: :.:.:.:: :::.
NP_005 TTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
310 320 330 340 350
>>NP_113667 (OMIM: 612031) inhibin beta E chain prepropr (350 aa)
initn: 627 init1: 278 opt: 552 Z-score: 372.9 bits: 77.7 E(85289): 4.9e-14
Smith-Waterman score: 668; 36.2% identity (59.9% similar) in 367 aa overlap (50-407:21-350)
20 30 40 50 60 70
pF1KB8 GWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVK
:. ..: :::: . . :. :: .:
NP_113 MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERAL--VLELAK
10 20 30 40
80 90 100 110 120 130
pF1KB8 RHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQER
..::. :.. .:: ::: :.::.. :::.:. :.: .:: .:.:
NP_113 QQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSV---------------APG-NGEE-
50 60 70 80 90
140 150 160 170 180 190
pF1KB8 VSEIISFAE-TDGLASSRVRLYFFISNEGNQNLFVVQASLWLY-LKLLPYVLEKGSRRKV
.:::: ::. .. : : .:. ...:. .: :::. : :: .: :
NP_113 ---VISFATVTDSTSAYSSLLTFHLSTPRSHHLY--HARLWLHVLPTLPGTL---CLRIF
100 110 120 130 140
200 210 220 230 240 250
pF1KB8 RVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQE
: ..:: .: ..:... ::::. : . .: :::. : .: : :.
NP_113 RWGPRRRRQG--SRTLLAEHHIT--NLGWHTLTLPSS--GL--RGEKSGVLKLQLD-CRP
150 160 170 180 190
260 270 280 290 300 310
pF1KB8 L-AVVPVFVDP----GEESHR-PFVVVQARLGD-SRHRIRKRGLECDGRTNLCCRQQFFI
: . : .: .:. ::. .. : .. . : :.: :. : ::::.. ..
NP_113 LEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYV
200 210 220 230 240 250
320 330 340 350 360 370
pF1KB8 DFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNS
::. .:: :::. : :: ::: :.:: .::: :: :.:::.:: . . . :... :
NP_113 DFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAST-S
260 270 280 290 300 310
380 390 400
pF1KB8 CCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
::.:: .:.::.: . :.:: :::.:.:: :::.
NP_113 CCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
320 330 340 350
>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b (240 aa)
initn: 329 init1: 186 opt: 347 Z-score: 243.8 bits: 53.3 E(85289): 7.7e-07
Smith-Waterman score: 354; 32.0% identity (59.6% similar) in 203 aa overlap (219-406:41-239)
190 200 210 220 230 240
pF1KB8 LEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNL
:. . : :..: .: :.. .:. ..
XP_011 FHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGF
20 30 40 50 60 70
250 260 270 280 290
pF1KB8 DVQCDSCQE-LAVVPVFVDPGEESH---------RPFVVVQARLGDSR--HRIRKRGLEC
:. .: .: : .. : ::..:. .. : .. :. .:: .
XP_011 VVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKH
80 90 100 110 120 130
300 310 320 330 340 350
pF1KB8 DGRTNL---CCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTA
: : : :. ...:: .::::::.:: ::.. ::.: :: :: .: . :
XP_011 KQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLA---DHLNSTNHA
140 150 160 170 180
360 370 380 390 400
pF1KB8 VVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
.: : . ..: ..::.::.::..::::.:.. ..: .. .:.:: :::
XP_011 IV-QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
190 200 210 220 230 240
>>NP_065685 (OMIM: 606522,613702,613703,613704) growth/d (364 aa)
initn: 370 init1: 198 opt: 350 Z-score: 243.3 bits: 53.8 E(85289): 8.2e-07
Smith-Waterman score: 350; 40.8% identity (64.1% similar) in 142 aa overlap (272-406:230-363)
250 260 270 280 290
pF1KB8 GERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKR-------GL
: ..:: :. : ::: :
NP_065 LFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLN-PDQCHPSRKRRAAIPVPKL
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB8 ECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAV
: ::: :.:.::.:: .::. ::::: :...:::.: :: :. . ..:.. .
NP_065 SC---KNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLT-ISLNSSNY---A
260 270 280 290 300 310
360 370 380 390 400
pF1KB8 VNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
: :....: .. ::::::: .:::: :.. :.. : .:.:.::::
NP_065 FMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
320 330 340 350 360
>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene (396 aa)
initn: 354 init1: 186 opt: 347 Z-score: 240.9 bits: 53.4 E(85289): 1.1e-06
Smith-Waterman score: 397; 26.1% identity (56.5% similar) in 356 aa overlap (73-406:48-395)
50 60 70 80 90 100
pF1KB8 PPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITH-AVPKA
. : . ..:: . .. ::. .. ::
NP_001 LGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPP
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB8 AMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYF
:. :. :.:. : : .:. :. . . :. : ... .: .:
NP_001 YMLDLYRR-HSGQ---PGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFF
80 90 100 110 120 130
170 180 190 200 210
pF1KB8 FISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVY--FQEQGHGDRW---NMVE
: . . :...: : .. . . .: ..: . :...: .. .... ...
NP_001 FNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLD
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB8 KR-VDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVP---VFVDPG--EE
: :. . : :..: .: :.. .:. .. :. .: : : .. . ..
NP_001 TRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQD
200 210 220 230 240 250
280 290 300 310 320
pF1KB8 SH-----RPFVVVQARLGDSR--HRIRKRGLECDGRTNL---CCRQQFFIDFRLIGWNDW
: ::..:. .. : .. :. .:: . : : : :. ...:: .:::::
NP_001 EHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDW
260 270 280 290 300 310
330 340 350 360 370 380
pF1KB8 IIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTM
:.:: ::.. ::.: :: :: .: . :.: : . ..: ..::.::.::..
NP_001 IVAPPGYHAFYCHGECPFPLAD---HLNSTNHAIV-QTLVNSVNSKIPKACCVPTELSAI
320 330 340 350 360
390 400
pF1KB8 SMLYFDDEYNIVKRDVPNMIVEECGCA
::::.:.. ..: .. .:.:: :::
NP_001 SMLYLDENEKVVLKNYQDMVVEGCGCR
370 380 390
407 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:52:22 2016 done: Sat Nov 5 00:52:23 2016
Total Scan time: 6.490 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]