Result of FASTA (omim) for
pFN21AF0190
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KF0190, 520 aa
1>>>pF1KF0190 520 - 520 aa - 520 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5734+/-0.000269; mu= 9.0551+/- 0.017
mean_var=152.7666+/-30.561, 0's: 0 Z-trim(123.3): 21 B-trim: 379 in 1/54
Lambda= 0.103767
statistics sampled from 44521 (44543) to 44521 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.485), width: 16
Scan time: 5.790
The best scores are: opt bits E(91774)
NP_734464 (OMIM: 607404) interferon lambda recepto ( 520) 3631 555.1 2e-157
XP_006710457 (OMIM: 607404) interferon lambda rece ( 489) 3200 490.5 5.1e-138
XP_016855968 (OMIM: 607404) interferon lambda rece ( 437) 3043 467.0 5.6e-131
NP_775087 (OMIM: 607404) interferon lambda recepto ( 491) 1872 291.7 3.6e-78
XP_024309436 (OMIM: 607404) interferon lambda rece ( 319) 1791 279.4 1.2e-74
NP_775088 (OMIM: 607404) interferon lambda recepto ( 244) 1555 244.0 4e-64
NP_851826 (OMIM: 606648) interleukin-22 receptor s ( 231) 227 45.2 0.00027
XP_016866443 (OMIM: 605620) interleukin-20 recepto ( 554) 206 42.3 0.0048
NP_851827 (OMIM: 606648) interleukin-22 receptor s ( 130) 194 40.1 0.0053
NP_000619 (OMIM: 123889,610424,612567) interleukin ( 325) 199 41.1 0.0065
>>NP_734464 (OMIM: 607404) interferon lambda receptor 1 (520 aa)
initn: 3631 init1: 3631 opt: 3631 Z-score: 2947.7 bits: 555.1 E(91774): 2e-157
Smith-Waterman score: 3631; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KF0 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_734 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KF0 SSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_734 SSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KF0 FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_734 FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KF0 PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_734 PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KF0 VIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLCPQKELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_734 VIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLCPQKELTR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KF0 GVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQEHQAPGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_734 GVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQEHQAPGHS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KF0 EAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPGQGPGGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_734 EAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPGQGPGGDG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KF0 HQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLTFCWESSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_734 HQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLTFCWESSP
430 440 450 460 470 480
490 500 510 520
pF1KF0 EEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
::::::::::::::::::::::::::::::::::::::::
NP_734 EEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
490 500 510 520
>>XP_006710457 (OMIM: 607404) interferon lambda receptor (489 aa)
initn: 3200 init1: 3200 opt: 3200 Z-score: 2599.4 bits: 490.5 E(91774): 5.1e-138
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 459 aa overlap (62-520:31-489)
40 50 60 70 80 90
pF1KF0 LLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVEECAGTKELLCSMMCLKKQD
::::::::::::::::::::::::::::::
XP_006 MEPEGELGSDSNICALPVASRHPSMCGIHISPTRRRWREVEECAGTKELLCSMMCLKKQD
10 20 30 40 50 60
100 110 120 130 140 150
pF1KF0 LYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQTEEILSANATYQLPPCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQTEEILSANATYQLPPCM
70 80 90 100 110 120
160 170 180 190 200 210
pF1KF0 PPLDLKYEVAFWKEGAGNKTLFPVTPHGQPVQITLQPAASEHHCLSARTIYTFSVPKYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPLDLKYEVAFWKEGAGNKTLFPVTPHGQPVQITLQPAASEHHCLSARTIYTFSVPKYSK
130 140 150 160 170 180
220 230 240 250 260 270
pF1KF0 FSKPTCFLLEVPEANWAFLVLPSLLILLLVIAAGGVIWKTLMGNPWFQRAKMPRALDFSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSKPTCFLLEVPEANWAFLVLPSLLILLLVIAAGGVIWKTLMGNPWFQRAKMPRALDFSG
190 200 210 220 230 240
280 290 300 310 320 330
pF1KF0 HTHPVATFQPSRPESVNDLFLCPQKELTRGVRPTPRVRAPATQQTRWKKDLAEDEEEEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTHPVATFQPSRPESVNDLFLCPQKELTRGVRPTPRVRAPATQQTRWKKDLAEDEEEEDE
250 260 270 280 290 300
340 350 360 370 380 390
pF1KF0 EDTEDGVSFQPYIEPPSFLGQEHQAPGHSEAGGVDSGRPRAPLVPSEGSSAWDSSDRSWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDTEDGVSFQPYIEPPSFLGQEHQAPGHSEAGGVDSGRPRAPLVPSEGSSAWDSSDRSWA
310 320 330 340 350 360
400 410 420 430 440 450
pF1KF0 STVDSSWDRAGSSGYLAEKGPGQGPGGDGHQESLPPPEFSKDSGFLEELPEDNLSSWATW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STVDSSWDRAGSSGYLAEKGPGQGPGGDGHQESLPPPEFSKDSGFLEELPEDNLSSWATW
370 380 390 400 410 420
460 470 480 490 500 510
pF1KF0 GTLPPEPNLVPGGPPVSLQTLTFCWESSPEEEEEARESEIEDSDAGSWGAESTQRTEDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTLPPEPNLVPGGPPVSLQTLTFCWESSPEEEEEARESEIEDSDAGSWGAESTQRTEDRG
430 440 450 460 470 480
520
pF1KF0 RTLGHYMAR
:::::::::
XP_006 RTLGHYMAR
>>XP_016855968 (OMIM: 607404) interferon lambda receptor (437 aa)
initn: 3043 init1: 3043 opt: 3043 Z-score: 2473.1 bits: 467.0 E(91774): 5.6e-131
Smith-Waterman score: 3043; 100.0% identity (100.0% similar) in 437 aa overlap (84-520:1-437)
60 70 80 90 100 110
pF1KF0 TYFVAYQSSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVE
::::::::::::::::::::::::::::::
XP_016 MMCLKKQDLYNKFKGRVRTVSPSSKSPWVE
10 20 30
120 130 140 150 160 170
pF1KF0 SEYLDYLFEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEYLDYLFEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLF
40 50 60 70 80 90
180 190 200 210 220 230
pF1KF0 PVTPHGQPVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTPHGQPVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLP
100 110 120 130 140 150
240 250 260 270 280 290
pF1KF0 SLLILLLVIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLILLLVIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLC
160 170 180 190 200 210
300 310 320 330 340 350
pF1KF0 PQKELTRGVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQKELTRGVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQE
220 230 240 250 260 270
360 370 380 390 400 410
pF1KF0 HQAPGHSEAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQAPGHSEAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPG
280 290 300 310 320 330
420 430 440 450 460 470
pF1KF0 QGPGGDGHQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGPGGDGHQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLT
340 350 360 370 380 390
480 490 500 510 520
pF1KF0 FCWESSPEEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCWESSPEEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
400 410 420 430
>>NP_775087 (OMIM: 607404) interferon lambda receptor 1 (491 aa)
initn: 1904 init1: 1856 opt: 1872 Z-score: 1524.9 bits: 291.7 E(91774): 3.6e-78
Smith-Waterman score: 3352; 94.4% identity (94.4% similar) in 520 aa overlap (1-520:1-491)
10 20 30 40 50 60
pF1KF0 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KF0 SSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KF0 FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KF0 PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KF0 VIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLCPQKELTR
::::::::::::::::::::::::::: ::::
NP_775 VIAAGGVIWKTLMGNPWFQRAKMPRAL-----------------------------ELTR
250 260 270
310 320 330 340 350 360
pF1KF0 GVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQEHQAPGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 GVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQEHQAPGHS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KF0 EAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPGQGPGGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPGQGPGGDG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KF0 HQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLTFCWESSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 HQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLTFCWESSP
400 410 420 430 440 450
490 500 510 520
pF1KF0 EEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
::::::::::::::::::::::::::::::::::::::::
NP_775 EEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
460 470 480 490
>>XP_024309436 (OMIM: 607404) interferon lambda receptor (319 aa)
initn: 1791 init1: 1791 opt: 1791 Z-score: 1462.0 bits: 279.4 E(91774): 1.2e-74
Smith-Waterman score: 1791; 99.2% identity (99.6% similar) in 256 aa overlap (265-520:64-319)
240 250 260 270 280 290
pF1KF0 LLILLLVIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLCP
:. :::::::::::::::::::::::::::
XP_024 ANTTASVPEPSTRSVSRNTASSLSPPASCWRSQDFSGHTHPVATFQPSRPESVNDLFLCP
40 50 60 70 80 90
300 310 320 330 340 350
pF1KF0 QKELTRGVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QKELTRGVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQPYIEPPSFLGQEH
100 110 120 130 140 150
360 370 380 390 400 410
pF1KF0 QAPGHSEAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QAPGHSEAGGVDSGRPRAPLVPSEGSSAWDSSDRSWASTVDSSWDRAGSSGYLAEKGPGQ
160 170 180 190 200 210
420 430 440 450 460 470
pF1KF0 GPGGDGHQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GPGGDGHQESLPPPEFSKDSGFLEELPEDNLSSWATWGTLPPEPNLVPGGPPVSLQTLTF
220 230 240 250 260 270
480 490 500 510 520
pF1KF0 CWESSPEEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
::::::::::::::::::::::::::::::::::::::::::::::
XP_024 CWESSPEEEEEARESEIEDSDAGSWGAESTQRTEDRGRTLGHYMAR
280 290 300 310
>>NP_775088 (OMIM: 607404) interferon lambda receptor 1 (244 aa)
initn: 1549 init1: 1549 opt: 1555 Z-score: 1272.7 bits: 244.0 E(91774): 4e-64
Smith-Waterman score: 1555; 98.7% identity (98.7% similar) in 227 aa overlap (1-227:1-227)
10 20 30 40 50 60
pF1KF0 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KF0 SSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KF0 FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 FEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KF0 PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLL
::::::::::::::::::::::::::::::::::::::::::: :
NP_775 PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPGLFWTHTPCGNLSAQQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KF0 VIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPSRPESVNDLFLCPQKELTR
NP_775 RVRE
>>NP_851826 (OMIM: 606648) interleukin-22 receptor subun (231 aa)
initn: 217 init1: 135 opt: 227 Z-score: 198.6 bits: 45.2 E(91774): 0.00027
Smith-Waterman score: 231; 30.8% identity (54.0% similar) in 211 aa overlap (27-223:31-231)
10 20 30 40 50
pF1KF0 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPG---LGNPQDV
:: : . :.:: : : :: :: .
NP_851 MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSS--
10 20 30 40 50
60 70 80 90 100 110
pF1KF0 TYFVAYQSSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVE
.::: :. .:.:.. :.: ::.:: :.. . .:. . . ::::..: .: : :
NP_851 VYFVQYKIYG-QRQWKNKEDCWGTQELSCDLTS-ETSDIQEPYYGRVRAASAGSYSEWSM
60 70 80 90 100 110
120 130 140 150 160
pF1KF0 SEYLDYLFEVEPAPPVLVLTQTEE----ILSANAT---YQLPPCMPPLD---LKYEVAFW
. . .:.. :::. .::.. :: : :: . : : :.: :
NP_851 TPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRV-FI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KF0 KEGAGNKTLFPVTPHGQPVQI-TLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEV
... .: . :.: .: : .: .:. :. :: . . :. :. : .:.
NP_851 INNSLEKEQKVYEGAHRAVEIEALTPHSS--YCVVAE-IYQPMLDRRSQRSEERC--VEI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KF0 PEANWAFLVLPSLLILLLVIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHPVATFQPS
:
NP_851 P
>>XP_016866443 (OMIM: 605620) interleukin-20 receptor su (554 aa)
initn: 104 init1: 67 opt: 206 Z-score: 176.3 bits: 42.3 E(91774): 0.0048
Smith-Waterman score: 220; 26.4% identity (54.2% similar) in 227 aa overlap (9-217:16-237)
10 20 30 40
pF1KF0 MAGPERWGPLLLCLLQAAPGR--P----RLAPPQNVTLLSQNFSVYLTWLPGL
:::: :: : :: : : : :.:.:: :.. : : :
XP_016 MRAPGRPALRPLPLPPLLLLLLAAPWGRAVPCVSGGLPKPANITFLSINMKNVLQWTPPE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KF0 G-NPQDVTYFVAYQSSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPS
: . ::: : : ...: . :: . .. :.. . .: ... ..:... .
XP_016 GLQGVKVTYTVQYFIRYGQKKWLNKSECRNINRTYCDLSA-ETSDYEHQYYAKVKAIWGT
70 80 90 100 110
110 120 130 140 150
pF1KF0 SKSPWVESEYLDYLFEVEPAPPVLVLTQTEE----ILSANATYQ-----LPPCMPPL--D
. : :.:: . ..:.. .:: ..:: :. .:.: .. :: : . .
XP_016 KCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSN
120 130 140 150 160 170
160 170 180 190 200 210
pF1KF0 LKYEVAFWKEGAGNKTLFPVTPHGQPVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKP
:::.:. . . :.: . . : :.: . .:. ... .. . :. .. :.
XP_016 LKYNVSVLNTKS-NRTWSQCVTNHTLVLTWLEP--NTLYCVHVES-FVPGPPRRAQPSEK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KF0 TCFLLEVPEANWAFLVLPSLLILLLVIAAGGVIWKTLMGNPWFQRAKMPRALDFSGHTHP
:
XP_016 QCARTLKDQSSEFKAKIIFWYVLPVSITVFLFSVMGYSIYRYIHVGKEKHPANLILIYGN
240 250 260 270 280 290
>>NP_851827 (OMIM: 606648) interleukin-22 receptor subun (130 aa)
initn: 227 init1: 135 opt: 194 Z-score: 175.4 bits: 40.1 E(91774): 0.0053
Smith-Waterman score: 194; 38.6% identity (62.5% similar) in 88 aa overlap (27-111:31-114)
10 20 30 40 50
pF1KF0 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPG---LGNPQDV
:: : . :.:: : : :: :: .
NP_851 MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSS--
10 20 30 40 50
60 70 80 90 100 110
pF1KF0 TYFVAYQSSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVE
.::: :. .:.:.. :.: ::.:: :.. . .:. . . ::::..: .: : :
NP_851 VYFVQYKIYG-QRQWKNKEDCWGTQELSCDLTS-ETSDIQEPYYGRVRAASAGSYSEWSM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KF0 SEYLDYLFEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLF
NP_851 TPRFTPWWERAKGL
120 130
>>NP_000619 (OMIM: 123889,610424,612567) interleukin-10 (325 aa)
initn: 93 init1: 64 opt: 199 Z-score: 173.9 bits: 41.1 E(91774): 0.0065
Smith-Waterman score: 199; 25.2% identity (53.0% similar) in 298 aa overlap (13-291:12-292)
10 20 30 40 50 60
pF1KF0 MAGPERWGPLLLCLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQ
::: .: : . ::.:: . : ::. : : ..:. . :
NP_000 MAWSLGSWLGGCLLVSALG--MVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYL
10 20 30 40 50
70 80 90 100 110
pF1KF0 SSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEY--LD
: : ... .: .: :.. :.: :. :::. . .: ::. . .:
NP_000 S---YRIFQD--KCMNTTLTECDFSSLSK---YGDHTLRVRAEFADEHSDWVNITFCPVD
60 70 80 90 100
120 130 140 150 160 170
pF1KF0 YLFEVEPAPPVLVLTQT-------EEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKT
. :. : ::... .: . :. . . . :.: .::.:. .:
NP_000 DTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYN--SWTYNVQYWKNGTDEK-
110 120 130 140 150 160
180 190 200 210 220
pF1KF0 LFPVTPHGQ-PVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEA--NW-
: .::. . : .:.: .. .:...: . . : ...:.:.: :. .:
NP_000 -FQITPQYDFEVLRNLEPWTT--YCVQVRG-FLPDRNKAGEWSEPVCEQTTHDETVPSWM
170 180 190 200 210 220
230 240 250 260 270 280
pF1KF0 -AFLVLPSL-LILLLVIAAGGVIWKTLMGNPW-FQ-RAKMPRAL-DFSGHTHPVATFQPS
: ... :. .. : ... ...: . . . :. : ..:. : .: :: : . . :
NP_000 VAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFS
230 240 250 260 270 280
290 300 310 320 330 340
pF1KF0 RPES-VNDLFLCPQKELTRGVRPTPRVRAPATQQTRWKKDLAEDEEEEDEEDTEDGVSFQ
: : ::.:
NP_000 FPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQS
290 300 310 320
520 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Jul 18 21:05:59 2019 done: Thu Jul 18 21:06:00 2019
Total Scan time: 5.790 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]