Result of FASTA (omim) for
pFN21AB3719
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3719, 866 aa
1>>>pF1KB3719 866 - 866 aa - 866 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0343+/-0.000302; mu= 13.6286+/- 0.019
mean_var=127.9370+/-25.761, 0's: 0 Z-trim(120.0): 47 B-trim: 0 in 0/53
Lambda= 0.113390
statistics sampled from 34712 (34760) to 34712 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.408), width: 16
Scan time: 12.640
The best scores are: opt bits E(85289)
NP_055154 (OMIM: 605461,613953) interleukin-17 rec ( 866) 6026 997.4 0
NP_001276834 (OMIM: 605461,613953) interleukin-17 ( 832) 3564 594.6 6.1e-169
NP_001305793 (OMIM: 606807,615267) interleukin-17 ( 595) 394 76.0 5.9e-13
XP_011532151 (OMIM: 606807,615267) PREDICTED: inte ( 595) 394 76.0 5.9e-13
XP_006713272 (OMIM: 606807,615267) PREDICTED: inte ( 595) 394 76.0 5.9e-13
XP_005265295 (OMIM: 606807,615267) PREDICTED: inte ( 711) 394 76.0 6.8e-13
NP_060033 (OMIM: 606807,615267) interleukin-17 rec ( 739) 394 76.0 7e-13
XP_005265367 (OMIM: 605458) PREDICTED: interleukin ( 531) 387 74.8 1.2e-12
XP_016862296 (OMIM: 605458) PREDICTED: interleukin ( 328) 302 60.8 1.2e-08
XP_011532243 (OMIM: 605458) PREDICTED: interleukin ( 357) 301 60.6 1.5e-08
NP_061195 (OMIM: 605458) interleukin-17 receptor B ( 502) 302 60.9 1.8e-08
XP_016862293 (OMIM: 605458) PREDICTED: interleukin ( 414) 274 56.2 3.6e-07
XP_005265368 (OMIM: 605458) PREDICTED: interleukin ( 515) 250 52.4 6.5e-06
XP_016862295 (OMIM: 605458) PREDICTED: interleukin ( 385) 189 42.3 0.0052
XP_016862838 (OMIM: 610925,616445) PREDICTED: inte ( 667) 192 43.0 0.0057
XP_016862837 (OMIM: 610925,616445) PREDICTED: inte ( 675) 192 43.0 0.0058
XP_016862836 (OMIM: 610925,616445) PREDICTED: inte ( 681) 192 43.0 0.0058
NP_001190194 (OMIM: 610925,616445) interleukin-17 ( 688) 192 43.0 0.0059
NP_001190193 (OMIM: 610925,616445) interleukin-17 ( 690) 192 43.0 0.0059
XP_016862835 (OMIM: 610925,616445) PREDICTED: inte ( 692) 192 43.0 0.0059
XP_016862834 (OMIM: 610925,616445) PREDICTED: inte ( 693) 192 43.0 0.0059
XP_016862833 (OMIM: 610925,616445) PREDICTED: inte ( 694) 192 43.0 0.0059
XP_016862832 (OMIM: 610925,616445) PREDICTED: inte ( 695) 192 43.0 0.0059
XP_016862831 (OMIM: 610925,616445) PREDICTED: inte ( 696) 192 43.0 0.0059
NP_116121 (OMIM: 610925,616445) interleukin-17 rec ( 705) 192 43.0 0.006
XP_016862830 (OMIM: 610925,616445) PREDICTED: inte ( 706) 192 43.0 0.006
NP_001190192 (OMIM: 610925,616445) interleukin-17 ( 707) 192 43.0 0.006
NP_703190 (OMIM: 610925,616445) interleukin-17 rec ( 720) 192 43.0 0.0061
XP_016862829 (OMIM: 610925,616445) PREDICTED: inte ( 721) 192 43.0 0.0061
XP_016862828 (OMIM: 610925,616445) PREDICTED: inte ( 746) 192 43.0 0.0063
XP_016862827 (OMIM: 610925,616445) PREDICTED: inte ( 750) 192 43.0 0.0063
XP_016862826 (OMIM: 610925,616445) PREDICTED: inte ( 752) 192 43.0 0.0063
XP_016862825 (OMIM: 610925,616445) PREDICTED: inte ( 761) 192 43.0 0.0064
XP_016862824 (OMIM: 610925,616445) PREDICTED: inte ( 763) 192 43.0 0.0064
XP_016862823 (OMIM: 610925,616445) PREDICTED: inte ( 767) 192 43.0 0.0064
XP_016862822 (OMIM: 610925,616445) PREDICTED: inte ( 774) 192 43.0 0.0065
XP_016862821 (OMIM: 610925,616445) PREDICTED: inte ( 776) 192 43.0 0.0065
XP_016862820 (OMIM: 610925,616445) PREDICTED: inte ( 777) 192 43.0 0.0065
XP_016862818 (OMIM: 610925,616445) PREDICTED: inte ( 778) 192 43.0 0.0065
XP_016862819 (OMIM: 610925,616445) PREDICTED: inte ( 778) 192 43.0 0.0065
XP_016862816 (OMIM: 610925,616445) PREDICTED: inte ( 779) 192 43.0 0.0065
XP_016862817 (OMIM: 610925,616445) PREDICTED: inte ( 779) 192 43.0 0.0065
NP_703191 (OMIM: 610925,616445) interleukin-17 rec ( 791) 192 43.0 0.0066
XP_016862815 (OMIM: 610925,616445) PREDICTED: inte ( 792) 192 43.0 0.0066
>>NP_055154 (OMIM: 605461,613953) interleukin-17 recepto (866 aa)
initn: 6026 init1: 6026 opt: 6026 Z-score: 5330.5 bits: 997.4 E(85289): 0
Smith-Waterman score: 6026; 100.0% identity (100.0% similar) in 866 aa overlap (1-866:1-866)
10 20 30 40 50 60
pF1KB3 MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ
790 800 810 820 830 840
850 860
pF1KB3 RQLLFRQLQKNSGWDTMGSESEGPSA
::::::::::::::::::::::::::
NP_055 RQLLFRQLQKNSGWDTMGSESEGPSA
850 860
>>NP_001276834 (OMIM: 605461,613953) interleukin-17 rece (832 aa)
initn: 3564 init1: 3564 opt: 3564 Z-score: 3154.1 bits: 594.6 E(85289): 6.1e-169
Smith-Waterman score: 5711; 96.1% identity (96.1% similar) in 866 aa overlap (1-866:1-832)
10 20 30 40 50 60
pF1KB3 MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGAARSPPSAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 VSCPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGSEKYSDDTK
:::::::::::::: ::::::::::::
NP_001 VSCPEMPDTPEPIP----------------------------------GPGSEKYSDDTK
310 320
370 380 390 400 410 420
pF1KB3 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB3 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFT
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB3 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLE
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB3 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPS
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB3 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDEEVFEEPLLPPGTGIVKRAPLVREPGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB3 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPGAGRNSVLFLP
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB3 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDPEDSPLGSSTPMASPDLLPEDVREHLEGLMLSLFEQSLSCQAQGGCSRPAMVLTDPHT
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB3 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQ
750 760 770 780 790 800
850 860
pF1KB3 RQLLFRQLQKNSGWDTMGSESEGPSA
::::::::::::::::::::::::::
NP_001 RQLLFRQLQKNSGWDTMGSESEGPSA
810 820 830
>>NP_001305793 (OMIM: 606807,615267) interleukin-17 rece (595 aa)
initn: 305 init1: 145 opt: 394 Z-score: 353.6 bits: 76.0 E(85289): 5.9e-13
Smith-Waterman score: 401; 25.8% identity (51.2% similar) in 570 aa overlap (225-768:62-582)
200 210 220 230 240 250
pF1KB3 PCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMH-HIP
: : : . . .:: : .. :. .. :
NP_001 HPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYK
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB3 APRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPI
. :.... . .: ..:. .. ..: ..: . .. :
NP_001 LKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDT---NTTRKVMHYALKPVHS
100 110 120 130 140
320 330 340 350 360 370
pF1KB3 PDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGS---EKYSDDTKYTDGLPAADL
: :. . . . . .. . .... ..: . . : :. :... :: .:: :
NP_001 PWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERL
150 160 170 180 190 200
380 390 400 410 420
pF1KB3 IPPPLKPRKVWIIYSA-DHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWV
: : ::.. ::. : ...:: :: :: :: :::::: :. .. . : ::
NP_001 RPRP----KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWV
210 220 230 240 250 260
430 440 450 460 470 480
pF1KB3 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPD
:.. ::. :::.::.: . .. . . .:. :.:: .:.. :
NP_001 ---IQKIHESQF-IIVVCSKGMKY----FVDKKNYKHKGGGRGSGKGELFLVAVSAIAEK
270 280 290 300 310
490 500 510 520 530 540
pF1KB3 FKRP-----ACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEV--YFRIQDLEMF
... : .. ... :: . ::.:::: .. . .: ::: . .. ... .: .
NP_001 LRQAKQSSSAALSKFIAVYF-DYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQ
320 330 340 350 360 370
550 560 570 580 590 600
pF1KB3 QPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPSLD
.::. : : : ::.:: .::.: .:. .... . ::::: . . : :
NP_001 EPGQHTRQG--SRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFV----PFHPPPLR
380 390 400 410 420
610 620 630 640 650 660
pF1KB3 EEVFEEPLLPP-GTGIVKRAPLVRE-PGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP
..::.: .:.: . . : :. :: .. ::: : : :
NP_001 ---YREPVLEKFDSGLVLNDVMCKPGPESDFCLKVE--------AAV------LGATG-P
430 440 450 460 470
670 680 690 700 710
pF1KB3 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPG-AGRNSVLF-
: . : ...:.: : : ::.:. : .: :::. :.: ..
NP_001 ADSQ-H----ESQHGGLDQDGEARPALDGSAALQPLLHTVKA----GSPSDMPRDSGIYD
480 490 500 510 520
720 730 740 750 760
pF1KB3 --LPVDPEDSPL--GSSTPMASPDLLPEDVR------EHLEGLMLSLFEQSLSCQAQGGC
.: . . :: : :: .. . : :.: :. . : . .: ::.:. ::
NP_001 SSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGC
530 540 550 560 570 580
770 780 790 800 810 820
pF1KB3 SRPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPL
NP_001 RSYTDELHAVAPL
590
>>XP_011532151 (OMIM: 606807,615267) PREDICTED: interleu (595 aa)
initn: 305 init1: 145 opt: 394 Z-score: 353.6 bits: 76.0 E(85289): 5.9e-13
Smith-Waterman score: 401; 25.8% identity (51.2% similar) in 570 aa overlap (225-768:62-582)
200 210 220 230 240 250
pF1KB3 PCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMH-HIP
: : : . . .:: : .. :. .. :
XP_011 HPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYK
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB3 APRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPI
. :.... . .: ..:. .. ..: ..: . .. :
XP_011 LKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDT---NTTRKVMHYALKPVHS
100 110 120 130 140
320 330 340 350 360 370
pF1KB3 PDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGS---EKYSDDTKYTDGLPAADL
: :. . . . . .. . .... ..: . . : :. :... :: .:: :
XP_011 PWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERL
150 160 170 180 190 200
380 390 400 410 420
pF1KB3 IPPPLKPRKVWIIYSA-DHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWV
: : ::.. ::. : ...:: :: :: :: :::::: :. .. . : ::
XP_011 RPRP----KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWV
210 220 230 240 250 260
430 440 450 460 470 480
pF1KB3 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPD
:.. ::. :::.::.: . .. . . .:. :.:: .:.. :
XP_011 ---IQKIHESQF-IIVVCSKGMKY----FVDKKNYKHKGGGRGSGKGELFLVAVSAIAEK
270 280 290 300 310
490 500 510 520 530 540
pF1KB3 FKRP-----ACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEV--YFRIQDLEMF
... : .. ... :: . ::.:::: .. . .: ::: . .. ... .: .
XP_011 LRQAKQSSSAALSKFIAVYF-DYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQ
320 330 340 350 360 370
550 560 570 580 590 600
pF1KB3 QPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPSLD
.::. : : : ::.:: .::.: .:. .... . ::::: . . : :
XP_011 EPGQHTRQG--SRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFV----PFHPPPLR
380 390 400 410 420
610 620 630 640 650 660
pF1KB3 EEVFEEPLLPP-GTGIVKRAPLVRE-PGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP
..::.: .:.: . . : :. :: .. ::: : : :
XP_011 ---YREPVLEKFDSGLVLNDVMCKPGPESDFCLKVE--------AAV------LGATG-P
430 440 450 460 470
670 680 690 700 710
pF1KB3 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPG-AGRNSVLF-
: . : ...:.: : : ::.:. : .: :::. :.: ..
XP_011 ADSQ-H----ESQHGGLDQDGEARPALDGSAALQPLLHTVKA----GSPSDMPRDSGIYD
480 490 500 510 520
720 730 740 750 760
pF1KB3 --LPVDPEDSPL--GSSTPMASPDLLPEDVR------EHLEGLMLSLFEQSLSCQAQGGC
.: . . :: : :: .. . : :.: :. . : . .: ::.:. ::
XP_011 SSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGC
530 540 550 560 570 580
770 780 790 800 810 820
pF1KB3 SRPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPL
XP_011 RSYTDELHAVAPL
590
>>XP_006713272 (OMIM: 606807,615267) PREDICTED: interleu (595 aa)
initn: 305 init1: 145 opt: 394 Z-score: 353.6 bits: 76.0 E(85289): 5.9e-13
Smith-Waterman score: 401; 25.8% identity (51.2% similar) in 570 aa overlap (225-768:62-582)
200 210 220 230 240 250
pF1KB3 PCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMH-HIP
: : : . . .:: : .. :. .. :
XP_006 HPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYK
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB3 APRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPI
. :.... . .: ..:. .. ..: ..: . .. :
XP_006 LKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDT---NTTRKVMHYALKPVHS
100 110 120 130 140
320 330 340 350 360 370
pF1KB3 PDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGS---EKYSDDTKYTDGLPAADL
: :. . . . . .. . .... ..: . . : :. :... :: .:: :
XP_006 PWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPRERL
150 160 170 180 190 200
380 390 400 410 420
pF1KB3 IPPPLKPRKVWIIYSA-DHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWV
: : ::.. ::. : ...:: :: :: :: :::::: :. .. . : ::
XP_006 RPRP----KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQREWV
210 220 230 240 250 260
430 440 450 460 470 480
pF1KB3 GRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPD
:.. ::. :::.::.: . .. . . .:. :.:: .:.. :
XP_006 ---IQKIHESQF-IIVVCSKGMKY----FVDKKNYKHKGGGRGSGKGELFLVAVSAIAEK
270 280 290 300 310
490 500 510 520 530 540
pF1KB3 FKRP-----ACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEV--YFRIQDLEMF
... : .. ... :: . ::.:::: .. . .: ::: . .. ... .: .
XP_006 LRQAKQSSSAALSKFIAVYF-DYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSRDHGLQ
320 330 340 350 360 370
550 560 570 580 590 600
pF1KB3 QPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQDAPSLD
.::. : : : ::.:: .::.: .:. .... . ::::: . . : :
XP_006 EPGQHTRQG--SRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFV----PFHPPPLR
380 390 400 410 420
610 620 630 640 650 660
pF1KB3 EEVFEEPLLPP-GTGIVKRAPLVRE-PGSQACLAIDPLVGEEGGAAVAKLEPHLQPRGQP
..::.: .:.: . . : :. :: .. ::: : : :
XP_006 ---YREPVLEKFDSGLVLNDVMCKPGPESDFCLKVE--------AAV------LGATG-P
430 440 450 460 470
670 680 690 700 710
pF1KB3 APQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPG-AGRNSVLF-
: . : ...:.: : : ::.:. : .: :::. :.: ..
XP_006 ADSQ-H----ESQHGGLDQDGEARPALDGSAALQPLLHTVKA----GSPSDMPRDSGIYD
480 490 500 510 520
720 730 740 750 760
pF1KB3 --LPVDPEDSPL--GSSTPMASPDLLPEDVR------EHLEGLMLSLFEQSLSCQAQGGC
.: . . :: : :: .. . : :.: :. . : . .: ::.:. ::
XP_006 SSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCKADLGC
530 540 550 560 570 580
770 780 790 800 810 820
pF1KB3 SRPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPL
XP_006 RSYTDELHAVAPL
590
>>XP_005265295 (OMIM: 606807,615267) PREDICTED: interleu (711 aa)
initn: 305 init1: 145 opt: 394 Z-score: 352.4 bits: 76.0 E(85289): 6.8e-13
Smith-Waterman score: 405; 23.6% identity (50.3% similar) in 755 aa overlap (47-768:24-698)
20 30 40 50 60 70
pF1KB3 GLLLLLLGVLAPGGASLRLLDHRALVCSQPGL-NCTVKNSTCLDDSWIHPRNL-TPSSPK
:: : : : ..: ....: . . .. .
XP_005 MKAAARPRLCVANEGVGPASRNSGLYNITFKYDNC--TTYLNPVGKHVIADAQ
10 20 30 40 50
80 90 100 110 120 130
pF1KB3 DLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSK
.. :. . : : .. : :. .: .:.: .. . .:... : : .. .:.
XP_005 NITISQYACHDQ-----VAVTILWS-PGALGIEFLKGFRVILEELKSEGRQCQQL-ILKD
60 70 80 90 100
140 150 160 170 180 190
pF1KB3 LRHHHRRWRFT--FSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKV
.. . .. : :. .. : . :. .: : .. :.. : . :. . .
XP_005 PKQLNSSFKRTGMESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACD---LLL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB3 TTPCMSSGSLWDP-NITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMH-
.. .: : :... : : . . .:: : .. :. ..
XP_005 QPDNLACKPFWKPRNLNI-----------------SQHGSDMQVSFDHAPHNFGFRFFYL
170 180 190 200
260 270 280 290 300 310
pF1KB3 HIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTP
: . :.... . .: ..:. .. ..: ..: . .. :
XP_005 HYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDT---NTTRKVMHYALKP
210 220 230 240 250 260
320 330 340 350 360
pF1KB3 EPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGS---EKYSDDTKYTDGLPA
: :. . . . . .. . .... ..: . . : :. :... :: .::
XP_005 VHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPR
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB3 ADLIPPPLKPRKVWIIYSA-DHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVM
: : : ::.. ::. : ...:: :: :: :: :::::: :. .. . :
XP_005 ERLRPRP----KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQR
330 340 350 360 370
430 440 450 460 470 480
pF1KB3 TWVGRQKQEMVESNSKIIVLCSRGTR--AKWQALLGRGAPVRLRCDHGKPVGDLFTAAMN
:: :.. ::. :::.::.: . . . .:. .:. :.:: .:..
XP_005 EWV---IQKIHESQF-IIVVCSKGMKYFVDKKNYKHKGG------GRGSGKGELFLVAVS
380 390 400 410 420
490 500 510 520 530
pF1KB3 MILPDFKRP-----ACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEV--YFRIQ
: ... : .. ... :: . ::.:::: .. . .: ::: . .. ... .
XP_005 AIAEKLRQAKQSSSAALSKFIAVYF-DYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSR
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB3 DLEMFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQD
: . .::. : : : ::.:: .::.: .:. .... . ::::: . .
XP_005 DHGLQEPGQHTRQG--SRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFV----PFH
490 500 510 520 530 540
600 610 620 630 640 650
pF1KB3 APSLDEEVFEEPLLPP-GTGIVKRAPLVRE-PGSQACLAIDPLVGEEGGAAVAKLEPHLQ
: : ..::.: .:.: . . : :. :: .. ::: :
XP_005 PPPLR---YREPVLEKFDSGLVLNDVMCKPGPESDFCLKVE--------AAV------LG
550 560 570 580
660 670 680 690 700 710
pF1KB3 PRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPG-AGRN
: :: . : ...:.: : : ::.:. : .: :::. :.
XP_005 ATG-PADSQ-HE----SQHGGLDQDGEARPALDGSAALQPLLHTVKA----GSPSDMPRD
590 600 610 620 630
720 730 740 750 760
pF1KB3 SVLF---LPVDPEDSPL--GSSTPMASPDLLPEDVR------EHLEGLMLSLFEQSLSCQ
: .. .: . . :: : :: .. . : :.: :. . : . .: ::.
XP_005 SGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCK
640 650 660 670 680 690
770 780 790 800 810 820
pF1KB3 AQGGCSRPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGK
:. ::
XP_005 ADLGCRSYTDELHAVAPL
700 710
>>NP_060033 (OMIM: 606807,615267) interleukin-17 recepto (739 aa)
initn: 305 init1: 145 opt: 394 Z-score: 352.2 bits: 76.0 E(85289): 7e-13
Smith-Waterman score: 405; 23.6% identity (50.3% similar) in 755 aa overlap (47-768:52-726)
20 30 40 50 60 70
pF1KB3 GLLLLLLGVLAPGGASLRLLDHRALVCSQPGL-NCTVKNSTCLDDSWIHPRNL-TPSSPK
:: : : : ..: ....: . . .. .
NP_060 QLAVAAGGSGRARGADTCGWRGVGPASRNSGLYNITFKYDNC--TTYLNPVGKHVIADAQ
30 40 50 60 70
80 90 100 110 120 130
pF1KB3 DLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSK
.. :. . : : .. : :. .: .:.: .. . .:... : : .. .:.
NP_060 NITISQYACHDQ-----VAVTILWS-PGALGIEFLKGFRVILEELKSEGRQCQQL-ILKD
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB3 LRHHHRRWRFT--FSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKV
.. . .. : :. .. : . :. .: : .. :.. : . :. . .
NP_060 PKQLNSSFKRTGMESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACD---LLL
140 150 160 170 180
200 210 220 230 240 250
pF1KB3 TTPCMSSGSLWDP-NITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMH-
.. .: : :... : : . . .:: : .. :. ..
NP_060 QPDNLACKPFWKPRNLNI-----------------SQHGSDMQVSFDHAPHNFGFRFFYL
190 200 210 220 230
260 270 280 290 300 310
pF1KB3 HIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTP
: . :.... . .: ..:. .. ..: ..: . .. :
NP_060 HYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDT---NTTRKVMHYALKP
240 250 260 270 280
320 330 340 350 360
pF1KB3 EPIPDYMPLWVYWFITGISILLVGSVILLIVCMTWRLAGPGS---EKYSDDTKYTDGLPA
: :. . . . . .. . .... ..: . . : :. :... :: .::
NP_060 VHSPWAGPIRAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYTAALPR
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB3 ADLIPPPLKPRKVWIIYSA-DHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVM
: : : ::.. ::. : ...:: :: :: :: :::::: :. .. . :
NP_060 ERLRPRP----KVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB3 TWVGRQKQEMVESNSKIIVLCSRGTR--AKWQALLGRGAPVRLRCDHGKPVGDLFTAAMN
:: :.. ::. :::.::.: . . . .:. .:. :.:: .:..
NP_060 EWV---IQKIHESQF-IIVVCSKGMKYFVDKKNYKHKGG------GRGSGKGELFLVAVS
410 420 430 440 450
490 500 510 520 530
pF1KB3 MILPDFKRP-----ACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEV--YFRIQ
: ... : .. ... :: . ::.:::: .. . .: ::: . .. ... .
NP_060 AIAEKLRQAKQSSSAALSKFIAVYF-DYSCEGDVPGILDLSTKYRLMDNLPQLCSHLHSR
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB3 DLEMFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVRCPDWFECENLYSADDQD
: . .::. : : : ::.:: .::.: .:. .... . ::::: . .
NP_060 DHGLQEPGQHTRQG--SRRNYFRSKSGRSLYVAICNMHQFIDEEPDWFEKQFV----PFH
520 530 540 550 560
600 610 620 630 640 650
pF1KB3 APSLDEEVFEEPLLPP-GTGIVKRAPLVRE-PGSQACLAIDPLVGEEGGAAVAKLEPHLQ
: : ..::.: .:.: . . : :. :: .. ::: :
NP_060 PPPLR---YREPVLEKFDSGLVLNDVMCKPGPESDFCLKVE--------AAV------LG
570 580 590 600 610
660 670 680 690 700 710
pF1KB3 PRGQPAPQPLHTLVLAAEEGALVAAVEPGPLADGAAVRLALAGEGEACPLLGSPG-AGRN
: :: . : ...:.: : : ::.:. : .: :::. :.
NP_060 ATG-PADSQ-HE----SQHGGLDQDGEARPALDGSAALQPLLHTVKA----GSPSDMPRD
620 630 640 650 660
720 730 740 750 760
pF1KB3 SVLF---LPVDPEDSPL--GSSTPMASPDLLPEDVR------EHLEGLMLSLFEQSLSCQ
: .. .: . . :: : :: .. . : :.: :. . : . .: ::.
NP_060 SGIYDSSVPSSELSLPLMEGLSTDQTETSSLTESVSSSSGLGEEEPPALPSKLLSSGSCK
670 680 690 700 710 720
770 780 790 800 810 820
pF1KB3 AQGGCSRPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGK
:. ::
NP_060 ADLGCRSYTDELHAVAPL
730
>>XP_005265367 (OMIM: 605458) PREDICTED: interleukin-17 (531 aa)
initn: 339 init1: 134 opt: 387 Z-score: 348.1 bits: 74.8 E(85289): 1.2e-12
Smith-Waterman score: 529; 25.0% identity (52.1% similar) in 516 aa overlap (39-526:13-498)
10 20 30 40 50 60
pF1KB3 SAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNL
:. : .: ..: . : . :. ..:
XP_005 MSLVLLSLAALCRSAVPREPTVQCG--SETGPSPEWMLQHDL
10 20 30 40
70 80 90 100 110 120
pF1KB3 TPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVL-QLNTNERLCV
:.. .::... . . :: . .. :.:..:::: :..... : . : . ::
XP_005 IPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 RFE----FLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVP
: . : .. : .: :.. : :. . : . .:..:. . : .: :: :
XP_005 RCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 DCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENH
: :: :...:::::::::. . . ..:.:: ...:. :. .
XP_005 GCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFS
170 180 190 200 210 220
250 260 270 280
pF1KB3 SCFE-HMHH-------IPAPRPEEFHQRSNVTLTLRNLKG-----CCRHQVQ------IQ
. :: :... ::. : .... .: :: .. .
XP_005 QVFEPHQKKQTRASVVIPVTGDSEGATVQGLACPKALAEGSQEDHCCSFFLEEMFVYVLT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB3 PFFSSCLNDCLRHSATVS-CPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLI-VC
:.: .: .::.::..:: ::. .: :. . :. . :::.. .:. .
XP_005 PYFPTCGSDCIRHKGTVVLCPQT-GVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIY
290 300 310 320 330
350 360 370 380 390 400
pF1KB3 MTWRLAGPGSEKYSDDTKYTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFL
. :: . ..: : :.:: :: ..: .. . .. :..::
XP_005 LMWRHERIKKTSFSTTT----------LLPPI----KVLVVYPSE-ICFHHTICYFTEFL
340 350 360 370 380
410 420 430 440 450 460
pF1KB3 LTACGTEVALDLLEEQAISEAGVMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGR-
. : .:: :. ... :.: : . :.. ::. . .:.. : : . . .. :.
XP_005 QNHCRSEVILEKWQKKKIAEMGPVQWLATQKK----AADKVVFLLSNDVNSVCDGTCGKS
390 400 410 420 430 440
470 480 490 500 510 520
pF1KB3 -GAPVRLRCDHGKPVGDLFTAAMNMILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAA
:.: .. ::: :.:.. :.. . ::: :: :.. : . ...
XP_005 EGSP-------SENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDY-NALSVC
450 460 470 480 490
530 540 550 560 570 580
pF1KB3 PRYPLMDRFEEVYFRIQDLEMFQPGRMHRVGELSGDNYLRSPGGRQLRAALDRFRDWQVR
:.: ::
XP_005 PKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
500 510 520 530
>>XP_016862296 (OMIM: 605458) PREDICTED: interleukin-17 (328 aa)
initn: 308 init1: 134 opt: 302 Z-score: 275.9 bits: 60.8 E(85289): 1.2e-08
Smith-Waterman score: 410; 26.6% identity (56.3% similar) in 316 aa overlap (39-346:13-314)
10 20 30 40 50 60
pF1KB3 SAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNL
:. : .: ..: . : . :. ..:
XP_016 MSLVLLSLAALCRSAVPREPTVQC--GSETGPSPEWMLQHDL
10 20 30 40
70 80 90 100 110 120
pF1KB3 TPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVL-QLNTNERLCV
:.. .::... . . :: . .. :.:..:::: :..... : . : . ::
XP_016 IPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 RFE----FLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVP
: . : .. : .: :.. : :. . : . .:..:. . : .: :: :
XP_016 RCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 DCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENH
: :: :...:::::::::. . . ..:.:: ...:. :. .:
XP_016 GCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALI-------QH
170 180 190 200 210
250 260 270 280 290 300
pF1KB3 SCFEHMHHIPAPRPEEFHQRSNVTLTLR-NLKGCCRHQVQIQPFFSSCLNDCLRHSATVS
: . . .. :. .. . :..:.. . . .: ::. :.: .: .::.::..::
XP_016 STIIGFSQVFEPHQKK-QTRASVVIPVTGDSEGAT---VQLTPYFPTCGSDCIRHKGTVV
220 230 240 250 260
310 320 330 340 350 360
pF1KB3 -CPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLI-VCMTWRLAGPGSEKYSDDTK
::. .: :. . :. . :::.. .:. . . ::
XP_016 LCPQT-GVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHEVRSSLKSGRKRK
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB3 YTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAI
>>XP_011532243 (OMIM: 605458) PREDICTED: interleukin-17 (357 aa)
initn: 296 init1: 134 opt: 301 Z-score: 274.5 bits: 60.6 E(85289): 1.5e-08
Smith-Waterman score: 376; 25.4% identity (52.7% similar) in 334 aa overlap (39-346:13-343)
10 20 30 40 50 60
pF1KB3 SAVPGPLLGLLLLLLGVLAPGGASLRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNL
:. : .: ..: . : . :. ..:
XP_011 MSLVLLSLAALCRSAVPREPTVQC--GSETGPSPEWMLQHDL
10 20 30 40
70 80 90 100 110 120
pF1KB3 TPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVL-QLNTNERLCV
:.. .::... . . :: . .. :.:..:::: :..... : . : . ::
XP_011 IPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 RFE----FLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVP
: . : .. : .: :.. : :. . : . .:..:. . : .: :: :
XP_011 RCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 DCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENH
: :: :...:::::::::. . . ..:.:: ...:. :. .
XP_011 GCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFS
170 180 190 200 210 220
250 260 270 280
pF1KB3 SCFE-HMHH-------IPAPRPEEFHQRSNVTLTLRNLKG-----CCRHQVQ------IQ
. :: :... ::. : .... .: :: .. .
XP_011 QVFEPHQKKQTRASVVIPVTGDSEGATVQGLACPKALAEGSQEDHCCSFFLEEMFVYVLT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB3 PFFSSCLNDCLRHSATVS-CPEMPDTPEPIPDYMPLWVYWFITGISILLVGSVILLI-VC
:.: .: .::.::..:: ::. .: :. . :. . :::.. .:. .
XP_011 PYFPTCGSDCIRHKGTVVLCPQT-GVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIY
290 300 310 320 330
350 360 370 380 390 400
pF1KB3 MTWRLAGPGSEKYSDDTKYTDGLPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFL
. ::
XP_011 LMWRHEVRSSLKSGRKRK
340 350
866 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:38:05 2016 done: Fri Nov 4 23:38:07 2016
Total Scan time: 12.640 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]