Result of FASTA (omim) for
pFN21AB6480
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6480, 337 aa
1>>>pF1KB6480 337 - 337 aa - 337 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9871+/-0.000317; mu= 18.5391+/- 0.020
mean_var=69.5590+/-14.151, 0's: 0 Z-trim(116.9): 36 B-trim: 160 in 1/55
Lambda= 0.153779
statistics sampled from 28338 (28374) to 28338 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.333), width: 16
Scan time: 8.360
The best scores are: opt bits E(85289)
NP_005525 (OMIM: 147569,614889) interferon gamma r ( 337) 2277 513.8 2e-145
NP_001316057 (OMIM: 147569,614889) interferon gamm ( 356) 2130 481.2 1.4e-135
XP_011527856 (OMIM: 147569,614889) PREDICTED: inte ( 339) 2118 478.6 8.5e-135
XP_011527855 (OMIM: 147569,614889) PREDICTED: inte ( 362) 2114 477.7 1.7e-134
NP_000619 (OMIM: 123889,610424,612567) interleukin ( 325) 306 76.5 8.5e-14
XP_005261021 (OMIM: 107450) PREDICTED: interferon ( 488) 232 60.3 1e-08
NP_000620 (OMIM: 107450) interferon alpha/beta rec ( 557) 232 60.3 1.1e-08
NP_653318 (OMIM: 605621) interleukin-20 receptor s ( 311) 191 51.0 3.9e-06
XP_011527854 (OMIM: 107450) PREDICTED: interferon ( 270) 189 50.5 4.8e-06
XP_016862121 (OMIM: 605621) PREDICTED: interleukin ( 264) 186 49.8 7.5e-06
XP_011511213 (OMIM: 605621) PREDICTED: interleukin ( 264) 186 49.8 7.5e-06
XP_006713728 (OMIM: 605621) PREDICTED: interleukin ( 264) 186 49.8 7.5e-06
XP_011511212 (OMIM: 605621) PREDICTED: interleukin ( 316) 176 47.7 4e-05
>>NP_005525 (OMIM: 147569,614889) interferon gamma recep (337 aa)
initn: 2277 init1: 2277 opt: 2277 Z-score: 2731.7 bits: 513.8 E(85289): 2e-145
Smith-Waterman score: 2277; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHYW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETMAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETMAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 ASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKDPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKDPTQ
250 260 270 280 290 300
310 320 330
pF1KB6 PILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
:::::::::::::::::::::::::::::::::::::
NP_005 PILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
310 320 330
>>NP_001316057 (OMIM: 147569,614889) interferon gamma re (356 aa)
initn: 2130 init1: 2130 opt: 2130 Z-score: 2555.1 bits: 481.2 E(85289): 1.4e-135
Smith-Waterman score: 2229; 94.7% identity (94.7% similar) in 356 aa overlap (1-337:1-356)
10 20 30 40
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPP-------------------DPLSQLPAPQHPKIRLY
:::::::::::::::::::::::: :::::::::::::::::
NP_001 MRPTLLWSLLLLLGVFAAAAAAPPAQLTLETYQEWCNDSAATHDPLSQLPAPQHPKIRLY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 NAEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 SAGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 PFDIADTSTAFFCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFDIADTSTAFFCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB6 NIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWF
250 260 270 280 290 300
290 300 310 320 330
pF1KB6 HTPPSIPLQIEEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTPPSIPLQIEEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
310 320 330 340 350
>>XP_011527856 (OMIM: 147569,614889) PREDICTED: interfer (339 aa)
initn: 2118 init1: 2118 opt: 2118 Z-score: 2541.0 bits: 478.6 E(85289): 8.5e-135
Smith-Waterman score: 2118; 98.7% identity (99.4% similar) in 317 aa overlap (21-337:23-339)
10 20 30 40 50
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNST
.: .:::::::::::::::::::::::::::::::::
XP_011 MSTPSSSESVNLGMCCLTYKRDSADVNPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNST
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 RPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 YWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 ADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKDP
250 260 270 280 290 300
300 310 320 330
pF1KB6 TQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
:::::::::::::::::::::::::::::::::::::::
XP_011 TQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
310 320 330
>>XP_011527855 (OMIM: 147569,614889) PREDICTED: interfer (362 aa)
initn: 2114 init1: 2114 opt: 2114 Z-score: 2535.8 bits: 477.7 E(85289): 1.7e-134
Smith-Waterman score: 2114; 100.0% identity (100.0% similar) in 312 aa overlap (26-337:51-362)
10 20 30 40 50
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALS
::::::::::::::::::::::::::::::
XP_011 MVPKDVHALILRVREPGNVLPDVQKGLRRYPLSQLPAPQHPKIRLYNAEQVLSWEPVALS
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB6 NSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRL
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB6 RAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCY
150 160 170 180 190 200
180 190 200 210 220 230
pF1KB6 YVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCY
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB6 ETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYL
270 280 290 300 310 320
300 310 320 330
pF1KB6 KDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
::::::::::::::::::::::::::::::::::::::::::
XP_011 KDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
330 340 350 360
>>NP_000619 (OMIM: 123889,610424,612567) interleukin-10 (325 aa)
initn: 158 init1: 73 opt: 306 Z-score: 368.7 bits: 76.5 E(85289): 8.5e-14
Smith-Waterman score: 335; 25.7% identity (56.0% similar) in 327 aa overlap (5-324:1-299)
10 20 30 40 50 60
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRP
. ::: :: ..: :...: :.. .. : ...:.:: :.....
NP_000 MAWSLGSWLGGCLLVSA-----LGMVPPPENVRMNSVNFKNILQWESPAFAKGN--
10 20 30 40
70 80 90 100 110 120
pF1KB6 VVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELG
... .: : . . : .: . : :::::.. : . :::.:::..
NP_000 LTFTAQ--YLSYRIFQD-------KCMNTTLTECDFSSLSKYGDH------TLRVRAEFA
50 60 70 80 90
130 140 150 160 170
pF1KB6 ALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP-----FDIADTSTAF--F
:: ::.. : .. .::: ...: :: .:: .: .. .... .
NP_000 DEHSDWVNIT-FCPVDDTIIGPP-GMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSW
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 CYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNIS
: :.::..: .. . . . : ::.: .::.::.. .: ... ..:. :.
NP_000 TYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRG-FLPDRN---KAGEWSEPV
160 170 180 190 200
240 250 260 270 280 290
pF1KB6 CYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEE
: .: : .. .: .: ... .. . .:: :. :: : :.: ...:
NP_000 CEQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKE
210 220 230 240 250 260
300 310 320 330
pF1KB6 YLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
.: : . : .. : ..::.:..:.:.
NP_000 FLGHPHHNTLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSCSLGTPPGQGPQS
270 280 290 300 310 320
>>XP_005261021 (OMIM: 107450) PREDICTED: interferon alph (488 aa)
initn: 178 init1: 81 opt: 232 Z-score: 277.5 bits: 60.3 E(85289): 1e-08
Smith-Waterman score: 232; 22.3% identity (52.1% similar) in 328 aa overlap (13-332:143-452)
10 20 30 40
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYN
.::.. . ..:: :.. .. . :
XP_005 NIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQN
120 130 140 150 160 170
50 60 70 80 90 100
pF1KB6 AEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPS
. ::.:. . .: : : . : . .: .: .. .:.: : :.
XP_005 QNYVLKWD-YTYANMTFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVF----PQ
180 190 200 210 220
110 120 130 140 150 160
pF1KB6 AGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP
: . . ::..: : : : :. .. . :: ... :. : ...:
XP_005 NVFQKGIYL-LRVQASDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAP
230 240 250 260 270 280
170 180 190 200 210
pF1KB6 FDIADTSTAF---FCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL--
. ..: . . : . .::. . . : ....... :::: :::....:. .
XP_005 KQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDE
290 300 310 320 330 340
220 230 240 250 260 270
pF1KB6 -WNKSNIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGL
:::..: :. : .: .... .. : .. :.: :. .: ::
XP_005 KLNKSSVF-----SDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----
350 360 370 380 390
280 290 300 310 320 330
pF1KB6 IKYWFHTPPSIPLQIEEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVL
:.: : . .:.::... : . .: . .... : . ...: : . : .: :
XP_005 INYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDED
400 410 420 430 440 450
pF1KB6 QTL
XP_005 HKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV
460 470 480
>>NP_000620 (OMIM: 107450) interferon alpha/beta recepto (557 aa)
initn: 157 init1: 81 opt: 232 Z-score: 276.7 bits: 60.3 E(85289): 1.1e-08
Smith-Waterman score: 232; 22.3% identity (52.1% similar) in 328 aa overlap (13-332:212-521)
10 20 30 40
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYN
.::.. . ..:: :.. .. . :
NP_000 NIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQN
190 200 210 220 230 240
50 60 70 80 90 100
pF1KB6 AEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPS
. ::.:. . .: : : . : . .: .: .. .:.: : :.
NP_000 QNYVLKWD-YTYANMTFQVQWLHAFLKRNPGNHLYKWKQIP-DCENVKTTQCVF----PQ
250 260 270 280 290
110 120 130 140 150 160
pF1KB6 AGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP
: . . ::..: : : : :. .. . :: ... :. : ...:
NP_000 NVFQKGIYL-LRVQASDGNNTSFWSEEIKFDTEIQAFLLPPV-FNIRSLSDSFHIYIGAP
300 310 320 330 340 350
170 180 190 200 210
pF1KB6 FDIADTSTAF---FCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLL--
. ..: . . : . .::. . . : ....... :::: :::....:. .
NP_000 KQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDE
360 370 380 390 400 410
220 230 240 250 260 270
pF1KB6 -WNKSNIFRVGHLSNISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGL
:::..: :. : .: .... .. : .. :.: :. .: ::
NP_000 KLNKSSVF-----SDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRC-----
420 430 440 450 460
280 290 300 310 320 330
pF1KB6 IKYWFHTPPSIPLQIEEYLKD-PTQPILEALDKDSSPKDDVWDSVSII-SFPEKEQEDVL
:.: : . .:.::... : . .: . .... : . ...: : . : .: :
NP_000 INYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDED
470 480 490 500 510 520
pF1KB6 QTL
NP_000 HKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV
530 540 550
>--
initn: 122 init1: 62 opt: 192 Z-score: 228.8 bits: 51.4 E(85289): 5.3e-06
Smith-Waterman score: 192; 24.3% identity (56.6% similar) in 226 aa overlap (1-218:1-210)
10 20 30 40 50 60
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRP
: .:: . :.: . : . . ..: .::. .. . . . .: : : .
NP_000 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRW------NRSDE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 VVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELG
: .: :.. .: . .... .: .::.:.:.:. : . . .. ::.:::
NP_000 SVGNVTFSFDYQKTGMDNWIKLS-GCQNITSTKCNFS----SLKLNVYEEIKLRIRAEKE
60 70 80 90 100
130 140 150 160 170
pF1KB6 ALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF----FCYY
:.: . : .:.. .:::: ... . ...:..: : .. :. : :
NP_000 NT-SSWYEVDSFTPFRKAQIGPPE-VHLEAEDKAIVIHIS-PGTKDSVMWALDGLSFTYS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 VHYWEKG-GIQQ-VKGPFRSNSISLDNLKPSRVYCLQVQAQLL--WNKSNIFRVGHLSNI
. :... :... ... . ..: .:.: .:::.:.: :: :
NP_000 LVIWKNSSGVEERIENIYSRHKIY--KLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTT
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 SCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIE
NP_000 VENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCE
230 240 250 260 270 280
>>NP_653318 (OMIM: 605621) interleukin-20 receptor subun (311 aa)
initn: 122 init1: 77 opt: 191 Z-score: 231.0 bits: 51.0 E(85289): 3.9e-06
Smith-Waterman score: 262; 27.0% identity (54.3% similar) in 278 aa overlap (6-279:11-263)
10 20 30 40 50
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALS
.:. :.. .: : .. :::::. .. : ...: : ::
NP_653 MQTFTMVLEEIWTSLFMWFFYALIPCLLTDEVAILPAPQNLSVLSTNMKHLLMWSPVIAP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 NSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRL
. : : :.:... . .:. : . :. . ::: : . .: :.. ::.
NP_653 GET--VYYSVEYQGEYESLYTSHIWIPSSWCSLTEGPECDVTD-DITATVPYN----LRV
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCY
:: ::. ::: . :: :. ..:.: :.:.. :.. : .
NP_653 RATLGSQTSAWSILK-HPFNRNSTILTRPGMEITKDGFHLVIELE---DLGPQ----FEF
120 130 140 150 160
180 190 200 210 220 230
pF1KB6 YVHYW--EKGGIQQVKGPFRSNSIS--LDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSN
: :: : :. ..:: ::..: :....:. .::...:. . . : : . .:.
NP_653 LVAYWRREPGAEEHVKM-VRSGGIPVHLETMEPGAAYCVKAQTFV----KAIGRYSAFSQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 ISCYETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQI
: :....: : ... :: . .: :. ..: :. :..:
NP_653 TECVEVQGEA-IPLVLALFAFVGFMLILVVVP----LFVWKMGRLLQYSCCPVVVLPDTL
230 240 250 260 270
300 310 320 330
pF1KB6 EEYLKDPTQPILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
NP_653 KITNSPQKLISCRREEVDACATAVMSPEELLRAWIS
280 290 300 310
>>XP_011527854 (OMIM: 107450) PREDICTED: interferon alph (270 aa)
initn: 122 init1: 62 opt: 189 Z-score: 229.5 bits: 50.5 E(85289): 4.8e-06
Smith-Waterman score: 213; 23.6% identity (55.6% similar) in 259 aa overlap (1-253:1-239)
10 20 30 40 50 60
pF1KB6 MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRP
: .:: . :.: . : . . ..: .::. .. . . . .: : : .
XP_011 MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRW------NRSDE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 VVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELG
: .: :.. .: . .... .: .::.:.:.:. : . . .. ::.:::
XP_011 SVGNVTFSFDYQKTGMDNWIKLS-GCQNITSTKCNFS----SLKLNVYEEIKLRIRAEKE
60 70 80 90 100
130 140 150 160 170
pF1KB6 ALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAF----FCYY
:.: . : .:.. .:::: ... . ...:..: : .. :. : :
XP_011 NT-SSWYEVDSFTPFRKAQIGPPE-VHLEAEDKAIVIHIS-PGTKDSVMWALDGLSFTYS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 VHYWEKG-GIQQ-VKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISC
. :... :... ... . ..: .:.: .:::.:.: :: . ...: : . :
XP_011 LVIWKNSSGVEERIENIYSRHKIY--KLSPETTYCLKVKAALLTS----WKIGVYSPVHC
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 YETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEY
.: .. . : .::
XP_011 IKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHLYFRRPR
230 240 250 260 270
>>XP_016862121 (OMIM: 605621) PREDICTED: interleukin-20 (264 aa)
initn: 59 init1: 59 opt: 186 Z-score: 226.0 bits: 49.8 E(85289): 7.5e-06
Smith-Waterman score: 205; 27.1% identity (54.6% similar) in 240 aa overlap (44-279:2-216)
20 30 40 50 60 70
pF1KB6 GVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQVQFKYTDSK
...: : :: . : : :.:... .
XP_016 MKHLLMWSPVIAPGET--VYYSVEYQGEYES
10 20
80 90 100 110 120 130
pF1KB6 WFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELGALHSAWVTMPWFQ
.:. : . :. . ::: : . .: :.. ::.:: ::. ::: .
XP_016 LYTSHIWIPSSWCSLTEGPECDVTD-DITATVPYN----LRVRATLGSQTSAWSILK-HP
30 40 50 60 70 80
140 150 160 170 180 190
pF1KB6 HYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHYW--EKGGIQQVKGP
:: :. ..:.: :.:.. :.. : . : :: : :. ..::
XP_016 FNRNSTILTRPGMEITKDGFHLVIELE---DLGPQ----FEFLVAYWRREPGAEEHVKM-
90 100 110 120 130
200 210 220 230 240
pF1KB6 FRSNSIS--LDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETMADASTELQQVI
::..: :....:. .::...:. . . : : . .:. : :....: : ..
XP_016 VRSGGIPVHLETMEPGAAYCVKAQTFV----KAIGRYSAFSQTECVEVQGEA-IPLVLAL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB6 LISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKDPTQPILEALDKD
. :: . .: :. ..: :. :..:
XP_016 FAFVGFMLILVVVP----LFVWKMGRLLQYSCCPVVVLPDTLKITNSPQKLISCRREEVD
200 210 220 230 240
337 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:15:28 2016 done: Sat Nov 5 01:15:29 2016
Total Scan time: 8.360 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]