Result of FASTA (ccds) for
pFN21AE0342
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0342, 625 aa
1>>>pF1KE0342 625 - 625 aa - 625 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2279+/-0.0007; mu= 16.5631+/- 0.043
mean_var=102.0471+/-20.380, 0's: 0 Z-trim(112.8): 27 B-trim: 5 in 1/52
Lambda= 0.126962
statistics sampled from 13467 (13484) to 13467 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.414), width: 16
Scan time: 3.940
The best scores are: opt bits E(32554)
CCDS13774.1 TRMT2A gene_id:27037|Hs108|chr22 ( 625) 4263 791.1 0
CCDS58793.1 TRMT2A gene_id:27037|Hs108|chr22 ( 562) 3718 691.3 9.1e-199
CCDS82693.1 TRMT2A gene_id:27037|Hs108|chr22 ( 643) 3085 575.4 8.1e-164
CCDS14477.1 TRMT2B gene_id:79979|Hs108|chrX ( 504) 1063 204.9 2.1e-52
CCDS55464.1 TRMT2B gene_id:79979|Hs108|chrX ( 459) 943 182.9 8e-46
>>CCDS13774.1 TRMT2A gene_id:27037|Hs108|chr22 (625 aa)
initn: 4263 init1: 4263 opt: 4263 Z-score: 4220.8 bits: 791.1 E(32554): 0
Smith-Waterman score: 4263; 100.0% identity (100.0% similar) in 625 aa overlap (1-625:1-625)
10 20 30 40 50 60
pF1KE0 MSENLDNEGPKPMESCGQESSSALSCPTVSVPPAAPAALEEVEKEGAGAATGPGPQPGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MSENLDNEGPKPMESCGQESSSALSCPTVSVPPAAPAALEEVEKEGAGAATGPGPQPGLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQPHKTKLFGQPPCAFVTFRSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQPHKTKLFGQPPCAFVTFRSAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERDKALRVLHGALWKGRPLSVRLARPKADPMARRRRQEGESEPPVTRVADVVTPLWTVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ERDKALRVLHGALWKGRPLSVRLARPKADPMARRRRQEGESEPPVTRVADVVTPLWTVPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIPEATKQVVKAFQEFIRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIPEATKQVVKAFQEFIRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTFRISPHAFFQVNTPAAEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTFRISPHAFFQVNTPAAEVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 YTVIQDWAQLDAGSMVLDVCCGTGTIGLALARKVKRVIGVELCPEAVEDARVNAQDNELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YTVIQDWAQLDAGSMVLDVCCGTGTIGLALARKVKRVIGVELCPEAVEDARVNAQDNELS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 NVEFHCGRAEDLVPTLVSRLASQHLVAILDPPRAGLHSKVILAIRRAKNLRRLLYVSCNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NVEFHCGRAEDLVPTLVSRLASQHLVAILDPPRAGLHSKVILAIRRAKNLRRLLYVSCNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 RAAMGNFVDLCRAPSNRVKGIPFRPVKAVAVDLFPQTPHCEMLILFERVEHPNGTGVLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RAAMGNFVDLCRAPSNRVKGIPFRPVKAVAVDLFPQTPHCEMLILFERVEHPNGTGVLGP
550 560 570 580 590 600
610 620
pF1KE0 HSPPAQPTPGPPDNTLQETGTFPSS
:::::::::::::::::::::::::
CCDS13 HSPPAQPTPGPPDNTLQETGTFPSS
610 620
>>CCDS58793.1 TRMT2A gene_id:27037|Hs108|chr22 (562 aa)
initn: 3718 init1: 3718 opt: 3718 Z-score: 3682.0 bits: 691.3 E(32554): 9.1e-199
Smith-Waterman score: 3718; 100.0% identity (100.0% similar) in 549 aa overlap (1-549:1-549)
10 20 30 40 50 60
pF1KE0 MSENLDNEGPKPMESCGQESSSALSCPTVSVPPAAPAALEEVEKEGAGAATGPGPQPGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MSENLDNEGPKPMESCGQESSSALSCPTVSVPPAAPAALEEVEKEGAGAATGPGPQPGLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQPHKTKLFGQPPCAFVTFRSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQPHKTKLFGQPPCAFVTFRSAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERDKALRVLHGALWKGRPLSVRLARPKADPMARRRRQEGESEPPVTRVADVVTPLWTVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ERDKALRVLHGALWKGRPLSVRLARPKADPMARRRRQEGESEPPVTRVADVVTPLWTVPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 AEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIPEATKQVVKAFQEFIRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 NKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIPEATKQVVKAFQEFIRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 YSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTFRISPHAFFQVNTPAAEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTFRISPHAFFQVNTPAAEVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 YTVIQDWAQLDAGSMVLDVCCGTGTIGLALARKVKRVIGVELCPEAVEDARVNAQDNELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 YTVIQDWAQLDAGSMVLDVCCGTGTIGLALARKVKRVIGVELCPEAVEDARVNAQDNELS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 NVEFHCGRAEDLVPTLVSRLASQHLVAILDPPRAGLHSKVILAIRRAKNLRRLLYVSCNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 NVEFHCGRAEDLVPTLVSRLASQHLVAILDPPRAGLHSKVILAIRRAKNLRRLLYVSCNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 RAAMGNFVDLCRAPSNRVKGIPFRPVKAVAVDLFPQTPHCEMLILFERVEHPNGTGVLGP
:::::::::
CCDS58 RAAMGNFVDAPLFPPQPLQSPI
550 560
>>CCDS82693.1 TRMT2A gene_id:27037|Hs108|chr22 (643 aa)
initn: 3085 init1: 3085 opt: 3085 Z-score: 3054.5 bits: 575.4 E(32554): 8.1e-164
Smith-Waterman score: 4217; 97.2% identity (97.2% similar) in 643 aa overlap (1-625:1-643)
10 20 30 40 50 60
pF1KE0 MSENLDNEGPKPMESCGQESSSALSCPTVSVPPAAPAALEEVEKEGAGAATGPGPQPGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MSENLDNEGPKPMESCGQESSSALSCPTVSVPPAAPAALEEVEKEGAGAATGPGPQPGLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQPHKTKLFGQPPCAFVTFRSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQPHKTKLFGQPPCAFVTFRSAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ERDKALRVLHGALWKGRPLSVRLARPKADPMARRRRQEGESEPPVTRVADVVTPLWTVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ERDKALRVLHGALWKGRPLSVRLARPKADPMARRRRQEGESEPPVTRVADVVTPLWTVPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 AEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIPEATKQVVKAFQEFIRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 NKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIPEATKQVVKAFQEFIRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 YSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTFRISPHAFFQVNTPAAEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTFRISPHAFFQVNTPAAEVL
370 380 390 400 410 420
430 440 450 460
pF1KE0 YTVIQDWAQLDAGSMVLDVCCGTGTIGLALAR------------------KVKRVIGVEL
:::::::::::::::::::::::::::::::: ::::::::::
CCDS82 YTVIQDWAQLDAGSMVLDVCCGTGTIGLALARGPMYSPPWVGRHHAFLFQKVKRVIGVEL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 CPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLVSRLASQHLVAILDPPRAGLHSKVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLVSRLASQHLVAILDPPRAGLHSKVIL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE0 AIRRAKNLRRLLYVSCNPRAAMGNFVDLCRAPSNRVKGIPFRPVKAVAVDLFPQTPHCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 AIRRAKNLRRLLYVSCNPRAAMGNFVDLCRAPSNRVKGIPFRPVKAVAVDLFPQTPHCEM
550 560 570 580 590 600
590 600 610 620
pF1KE0 LILFERVEHPNGTGVLGPHSPPAQPTPGPPDNTLQETGTFPSS
:::::::::::::::::::::::::::::::::::::::::::
CCDS82 LILFERVEHPNGTGVLGPHSPPAQPTPGPPDNTLQETGTFPSS
610 620 630 640
>>CCDS14477.1 TRMT2B gene_id:79979|Hs108|chrX (504 aa)
initn: 573 init1: 371 opt: 1063 Z-score: 1054.4 bits: 204.9 E(32554): 2.1e-52
Smith-Waterman score: 1065; 37.3% identity (63.3% similar) in 520 aa overlap (77-588:1-504)
50 60 70 80 90 100
pF1KE0 AGAATGPGPQPGLYSYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGL--QPHKTK
. .. :.. . ..: :.. :: .:
CCDS14 MAGLKRRVPLHSLRYFISMVGLFSKPGLLP
10 20 30
110 120 130 140 150 160
pF1KE0 LFGQ-PPCAFVTFRSAAERDKALRVLHGALWKGRPLSVRLARPKA-DPMARRRRQEGESE
... :: : ... . ::. ::. . .:. :. .: .
CCDS14 WYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQ---KKPSHLGPL------DGSWQ
40 50 60 70 80
170 180 190 200 210 220
pF1KE0 PPVTRVADVVTPLWTVPYAEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNK
:.:::::::: . : :::. : ...::.: . : : . . . : ..
CCDS14 E---RLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQMLNGVSVTTAVP---KSER
90 100 110 120 130
230 240 250 260 270 280
pF1KE0 ACCPLEGVRPSPQQTEYRNKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIP
: :. . ::: . :::: : :. : ::. .::: :: .. :. . . .::
CCDS14 LSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIP
140 150 160 170 180 190
290 300 310 320 330 340
pF1KE0 EATKQVVKAFQEFIRSTPYSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEEL
: .::.. .. :.:..: :.:..:::::. . ..::: ::::::: :::
CCDS14 EKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEEL
200 210 220 230 240 250
350 360 370 380 390 400
pF1KE0 AELKTSLAQHFTAGPGRASGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTF
: . . : ::: : :.: ::: : . . :.. : . . :. : :.::.: .
CCDS14 HVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQS-PYQLLFGEPYIFEELLSLKI
260 270 280 290 300 310
410 420 430 440 450 460
pF1KE0 RISPHAFFQVNTPAAEVLYTVIQDWAQLDAGSMVLDVCCGTGTIGLALARKVKRVIGVEL
:::: ::::.:: .::.:: .. . . ... ...::.:::::.:::.::....::.:.::
CCDS14 RISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIEL
320 330 340 350 360 370
470 480 490 500 510 520
pF1KE0 CPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLV-SRLASQHLVAILDPPRAGLHSKVI
.:::::: .: : ..: ::: :.:: ..: :. :. .: .::...: ::::: :::
CCDS14 LEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVI
380 390 400 410 420 430
530 540 550 560 570
pF1KE0 LAIRRAKNLRRLLYVSCNPRA-AMGNFVDLCRAP--SNRVKGIPFRPVKAVAVDLFPQTP
::: . .. :..:::. .. . : ..:: : .... : :: .:: :::::.::
CCDS14 QAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFVLQQAVPVDLFPHTP
440 450 460 470 480 490
580 590 600 610 620
pF1KE0 HCEMLILFERVEHPNGTGVLGPHSPPAQPTPGPPDNTLQETGTFPSS
:::...:: :
CCDS14 HCELVLLFTR
500
>>CCDS55464.1 TRMT2B gene_id:79979|Hs108|chrX (459 aa)
initn: 529 init1: 349 opt: 943 Z-score: 936.2 bits: 182.9 E(32554): 8e-46
Smith-Waterman score: 943; 42.9% identity (69.1% similar) in 359 aa overlap (234-588:102-459)
210 220 230 240 250 260
pF1KE0 STNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYRNKCEFLVGVGVDGEDNTVGCRLG
: . :::: : :. : ::. .::: ::
CCDS55 HLGPLDGSWQERLADVVTPLWRLSYEEQLKPVINGYRNKSTFSVNRGPDGNPKTVGFYLG
80 90 100 110 120 130
270 280 290 300 310 320
pF1KE0 KYKGGTCAVAAPFDTVHIPEATKQVVKAFQEFIRSTPYSAYDPETYTGHWKQLTVRTSRR
.. :. . . .::: .::.. .. :.:..: :.:..:::::. .
CCDS55 TWRDGNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQ
140 150 160 170 180 190
330 340 350 360 370 380
pF1KE0 HQAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRASGVTCLYFVEEGQRKTPSQEGLP
..::: ::::::: ::: : . . : ::: : :.: ::: : . . :.. :
CCDS55 GHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQS-P
200 210 220 230 240 250
390 400 410 420 430 440
pF1KE0 LEHVAGDRCIHEDLLGLTFRISPHAFFQVNTPAAEVLYTVIQDWAQLDAGSMVLDVCCGT
. . :. : :.::.: .:::: ::::.:: .::.:: .. . . ... ...::.::::
CCDS55 YQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGT
260 270 280 290 300 310
450 460 470 480 490 500
pF1KE0 GTIGLALARKVKRVIGVELCPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLV-SRLAS
:.:::.::....::.:.:: .:::::: .: : ..: ::: :.:: ..: :. :. .
CCDS55 GVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDG
320 330 340 350 360 370
510 520 530 540 550
pF1KE0 QHLVAILDPPRAGLHSKVILAIRRAKNLRRLLYVSCNPRA-AMGNFVDLCRAP--SNRVK
: .::...: ::::: ::: ::: . .. :..:::. .. . : ..:: : ....
CCDS55 QSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLL
380 390 400 410 420 430
560 570 580 590 600 610
pF1KE0 GIPFRPVKAVAVDLFPQTPHCEMLILFERVEHPNGTGVLGPHSPPAQPTPGPPDNTLQET
: :: .:: :::::.:::::...:: :
CCDS55 GEPFVLQQAVPVDLFPHTPHCELVLLFTR
440 450
625 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:05:07 2016 done: Thu Nov 3 15:05:08 2016
Total Scan time: 3.940 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]