Result of FASTA (omim) for
pFN21AB6452
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6452, 350 aa
1>>>pF1KB6452 350 - 350 aa - 350 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0405+/-0.000735; mu= -12.4430+/- 0.043
mean_var=664.6672+/-150.469, 0's: 0 Z-trim(113.1): 1001 B-trim: 1762 in 2/51
Lambda= 0.049748
statistics sampled from 21047 (22333) to 21047 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.262), width: 16
Scan time: 6.550
The best scores are: opt bits E(85289)
NP_001887 (OMIM: 115442) casein kinase II subunit ( 350) 2372 186.2 9.5e-47
NP_808227 (OMIM: 115440,617062) casein kinase II s ( 391) 1980 158.1 3e-38
NP_001886 (OMIM: 115440,617062) casein kinase II s ( 391) 1980 158.1 3e-38
XP_005255857 (OMIM: 115442) PREDICTED: casein kina ( 299) 1585 129.6 8.8e-30
XP_005255858 (OMIM: 115442) PREDICTED: casein kina ( 213) 1477 121.6 1.6e-27
XP_016878434 (OMIM: 115442) PREDICTED: casein kina ( 242) 1446 119.5 7.9e-27
NP_808228 (OMIM: 115440,617062) casein kinase II s ( 255) 1226 103.7 4.6e-22
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 513 52.8 1.4e-06
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 510 52.5 1.6e-06
NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 506 52.3 2e-06
NP_002960 (OMIM: 602399) mitogen-activated protein ( 367) 505 52.2 2.1e-06
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 499 51.6 2.5e-06
NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384) 472 49.9 1.1e-05
XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384) 472 49.9 1.1e-05
XP_005246838 (OMIM: 616147) PREDICTED: cyclin-depe ( 435) 472 49.9 1.2e-05
XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 470 49.7 1.3e-05
NP_001034892 (OMIM: 610076) cyclin-dependent kinas ( 346) 467 49.4 1.4e-05
NP_001248365 (OMIM: 616147) cyclin-dependent kinas ( 400) 468 49.6 1.4e-05
XP_011509952 (OMIM: 616147) PREDICTED: cyclin-depe ( 412) 468 49.6 1.4e-05
XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 470 49.9 1.4e-05
XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 470 49.9 1.4e-05
XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 470 49.9 1.4e-05
XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 470 49.9 1.4e-05
NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 470 49.9 1.4e-05
XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 470 49.9 1.4e-05
XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 470 49.9 1.4e-05
XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 470 49.9 1.4e-05
XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 470 49.9 1.4e-05
XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 470 49.9 1.4e-05
NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 470 49.9 1.4e-05
XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 470 49.9 1.4e-05
NP_001248364 (OMIM: 616147) cyclin-dependent kinas ( 429) 468 49.6 1.5e-05
XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 470 49.9 1.5e-05
XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 470 49.9 1.5e-05
XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 470 49.9 1.5e-05
NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 470 50.0 1.5e-05
XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 470 50.0 1.5e-05
XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 466 49.5 1.6e-05
NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423) 466 49.5 1.6e-05
XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 466 49.5 1.6e-05
XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 466 49.5 1.6e-05
XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 466 49.5 1.6e-05
XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423) 466 49.5 1.6e-05
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 468 49.8 1.6e-05
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 468 49.8 1.6e-05
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 468 49.8 1.6e-05
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 468 49.8 1.6e-05
XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450) 466 49.5 1.7e-05
NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451) 466 49.5 1.7e-05
XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469) 466 49.6 1.7e-05
>>NP_001887 (OMIM: 115442) casein kinase II subunit alph (350 aa)
initn: 2372 init1: 2372 opt: 2372 Z-score: 960.2 bits: 186.2 E(85289): 9.5e-47
Smith-Waterman score: 2372; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)
10 20 30 40 50 60
pF1KB6 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
310 320 330 340 350
>>NP_808227 (OMIM: 115440,617062) casein kinase II subun (391 aa)
initn: 1969 init1: 1969 opt: 1980 Z-score: 807.7 bits: 158.1 E(85289): 3e-38
Smith-Waterman score: 1980; 85.3% identity (94.9% similar) in 334 aa overlap (1-334:1-333)
10 20 30 40 50 60
pF1KB6 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
: ::. ::::::..::. : :::::::.:: :::::::::::::::::::::::::::
NP_808 MSGPVP-SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINI
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
::::.:::::::::::::::::.::::::::: ::: : : ::::::.:::::::..:::
NP_808 TNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
::::::: :::.::::::::.::::::::: ::::::::::::::::...::::::::::
NP_808 DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
:::::.:::::::::::::::::::::::::::::::::::::::::::.::::::.:::
NP_808 EFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
:::::::::::::.:: :. ::.:.:::.::::::.::::::: :.::::.:::::::::
NP_808 DQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD
240 250 260 270 280 290
310 320 330 340 350
pF1KB6 LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
.::::::::::.::::.::::::::: :::.:..
NP_808 FLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVP
300 310 320 330 340 350
NP_808 TPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
360 370 380 390
>>NP_001886 (OMIM: 115440,617062) casein kinase II subun (391 aa)
initn: 1969 init1: 1969 opt: 1980 Z-score: 807.7 bits: 158.1 E(85289): 3e-38
Smith-Waterman score: 1980; 85.3% identity (94.9% similar) in 334 aa overlap (1-334:1-333)
10 20 30 40 50 60
pF1KB6 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
: ::. ::::::..::. : :::::::.:: :::::::::::::::::::::::::::
NP_001 MSGPVP-SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINI
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
::::.:::::::::::::::::.::::::::: ::: : : ::::::.:::::::..:::
NP_001 TNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
::::::: :::.::::::::.::::::::: ::::::::::::::::...::::::::::
NP_001 DFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
:::::.:::::::::::::::::::::::::::::::::::::::::::.::::::.:::
NP_001 EFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
:::::::::::::.:: :. ::.:.:::.::::::.::::::: :.::::.:::::::::
NP_001 DQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALD
240 250 260 270 280 290
310 320 330 340 350
pF1KB6 LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
.::::::::::.::::.::::::::: :::.:..
NP_001 FLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVP
300 310 320 330 340 350
NP_001 TPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
360 370 380 390
>>XP_005255857 (OMIM: 115442) PREDICTED: casein kinase I (299 aa)
initn: 1578 init1: 1578 opt: 1585 Z-score: 655.7 bits: 129.6 E(85289): 8.8e-30
Smith-Waterman score: 1941; 85.4% identity (85.4% similar) in 350 aa overlap (1-350:1-299)
10 20 30 40 50 60
pF1KB6 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNT
::::::::::::
XP_005 TNNERVVVKILK------------------------------------------------
70
130 140 150 160 170 180
pF1KB6 DFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ---QLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLA
80 90 100 110 120
190 200 210 220 230 240
pF1KB6 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNY
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB6 DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALD
190 200 210 220 230 240
310 320 330 340 350
pF1KB6 LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
250 260 270 280 290
>>XP_005255858 (OMIM: 115442) PREDICTED: casein kinase I (213 aa)
initn: 1477 init1: 1477 opt: 1477 Z-score: 615.2 bits: 121.6 E(85289): 1.6e-27
Smith-Waterman score: 1477; 100.0% identity (100.0% similar) in 213 aa overlap (138-350:1-213)
110 120 130 140 150 160
pF1KB6 KTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDH
::::::::::::::::::::::::::::::
XP_005 MYELLKALDYCHSKGIMHRDVKPHNVMIDH
10 20 30
170 180 190 200 210 220
pF1KB6 QQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 FRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLT
160 170 180 190 200 210
350
pF1KB6 AAR
:::
XP_005 AAR
>>XP_016878434 (OMIM: 115442) PREDICTED: casein kinase I (242 aa)
initn: 1446 init1: 1446 opt: 1446 Z-score: 602.6 bits: 119.5 E(85289): 7.9e-27
Smith-Waterman score: 1446; 100.0% identity (100.0% similar) in 208 aa overlap (143-350:35-242)
120 130 140 150 160 170
pF1KB6 VFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKL
::::::::::::::::::::::::::::::
XP_016 NPNVHQLVVEYYSARKNNLDESQKQYTEGKKALDYCHSKGIMHRDVKPHNVMIDHQQKKL
10 20 30 40 50 60
180 190 200 210 220 230
pF1KB6 RLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREP
70 80 90 100 110 120
240 250 260 270 280 290
pF1KB6 FFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRH
130 140 150 160 170 180
300 310 320 330 340 350
pF1KB6 LVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR
190 200 210 220 230 240
>>NP_808228 (OMIM: 115440,617062) casein kinase II subun (255 aa)
initn: 1226 init1: 1226 opt: 1226 Z-score: 517.1 bits: 103.7 E(85289): 4.6e-22
Smith-Waterman score: 1226; 86.8% identity (97.5% similar) in 197 aa overlap (138-334:1-197)
110 120 130 140 150 160
pF1KB6 KTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDH
:::.::::::::: ::::::::::::::::
NP_808 MYEILKALDYCHSMGIMHRDVKPHNVMIDH
10 20 30
170 180 190 200 210 220
pF1KB6 QQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI
...:::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_808 EHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB6 FRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH
::.::::::.::::::::::::::::.:: :. ::.:.:::.::::::.::::::: :.:
NP_808 FRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVH
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB6 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLT
:::.:::::::::.::::::::::.::::.::::::::: :::.:..
NP_808 SENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPV
160 170 180 190 200 210
350
pF1KB6 AAR
NP_808 SSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
220 230 240 250
>>NP_620581 (OMIM: 600289) mitogen-activated protein kin (360 aa)
initn: 442 init1: 131 opt: 513 Z-score: 239.1 bits: 52.8 E(85289): 1.4e-06
Smith-Waterman score: 513; 30.5% identity (62.2% similar) in 328 aa overlap (24-338:8-321)
10 20 30 40 50 60
pF1KB6 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
.. : . : . :: . .: : :. : :..
NP_620 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDT
10 20 30 40
70 80 90 100 110
pF1KB6 TNNERVVVKIL-KP----VKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPAL---
.. ::.:: : .: .. :. ::...:.... :.: :.: : :. . .
NP_620 KTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKH-ENVIGLLD-VFTPARSLEEFNDV
50 60 70 80 90 100
120 130 140 150 160
pF1KB6 -VFEYINNTDFKQLY--QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQ
. .. ..:.... : ::: ..: .:..:..: : :: :.:::.:: :. .. ..
NP_620 YLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVN-ED
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 KKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR
.:...:.:::. : .:.. ::.:....::...... :. ..:.::.::..: ..
NP_620 CELKILDFGLAR--HTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTG
170 180 190 200 210
230 240 250 260 270 280
pF1KB6 REPFFHGQDNYDQLVRIAKVLGTE--ELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH
: .: : :. ::: : ...:: :: ::: . .. . : : . . : .
NP_620 RT-LFPGTDHIDQLKLILRLVGTPGAEL---LKKISSESARNYIQSLTQMPKMNFANVFI
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB6 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLT
. : : :.:::.:.: : ..:.:: .:. : :: ...: ::
NP_620 GAN-----PLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESR
280 290 300 310 320 330
350
pF1KB6 AAR
NP_620 DLLIDEWKSLTYDEVISFVPPPLDQEEMES
340 350 360
>>NP_002742 (OMIM: 602898) mitogen-activated protein kin (364 aa)
initn: 369 init1: 131 opt: 510 Z-score: 237.8 bits: 52.5 E(85289): 1.6e-06
Smith-Waterman score: 510; 30.2% identity (62.5% similar) in 328 aa overlap (24-338:8-321)
10 20 30 40 50 60
pF1KB6 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
.. : . : . : .: .: : :. : : .
NP_002 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDA
10 20 30 40
70 80 90 100 110
pF1KB6 TNNERVVVKIL-KP----VKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFE
..:.:: : .: .. .. ::...:..:. :.: :.: : :... .
NP_002 RLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKH-ENVIGLLD-VFTPATSIEDFSEV
50 60 70 80 90 100
120 130 140 150 160
pF1KB6 YINNT----DFKQLY--QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQ
:. .: :.... : :.: ..: .:.::..: : :: ::.:::.:: :: .. ..
NP_002 YLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVN-ED
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 KKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR
.::..:.:::. . .:.. ::.:....::...... :. ..:.::.::..: .. .
NP_002 CELRILDFGLAR--QADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELL-Q
170 180 190 200 210
230 240 250 260 270 280
pF1KB6 REPFFHGQDNYDQLVRIAKVLGTE--ELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIH
. .: :.: ::: :: .:.:: :. . ... : . . : .: ....
NP_002 GKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHART---YIQSLPPMPQKDLSSIFR
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB6 SENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLT
. : : :.::: ..: : .::..: ::. : :: ...: :.
NP_002 GAN-----PLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAK
280 290 300 310 320 330
350
pF1KB6 AAR
NP_002 ERTLEEWKELTYQEVLSFKPPEPPKPPGSLEIEQ
340 350 360
>>NP_001306 (OMIM: 600289) mitogen-activated protein kin (360 aa)
initn: 399 init1: 131 opt: 506 Z-score: 236.3 bits: 52.3 E(85289): 2e-06
Smith-Waterman score: 506; 29.1% identity (62.3% similar) in 326 aa overlap (24-338:8-321)
10 20 30 40 50 60
pF1KB6 MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINI
.. : . : . :: . .: : :. : :..
NP_001 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDT
10 20 30 40
70 80 90 100 110
pF1KB6 TNNERVVVKIL-KP----VKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPAL---
.. ::.:: : .: .. :. ::...:.... :.: :.: : :. . .
NP_001 KTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKH-ENVIGLLD-VFTPARSLEEFNDV
50 60 70 80 90 100
120 130 140 150 160
pF1KB6 -VFEYINNTDFKQLY--QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQ
. .. ..:.... : ::: ..: .:..:..: : :: :.:::.:: :. .. ..
NP_001 YLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVN-ED
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 KKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFR
.:...:.:::. : .:.. ::.:....::...... :. ..:.::.::..: ..
NP_001 CELKILDFGLAR--HTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTG
170 180 190 200 210
230 240 250 260 270 280
pF1KB6 REPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSE
: .: : :. .:: .: .. :: : .... .. . : : . . : . .
NP_001 RT-LFPGTDHINQLQQIMRLTGTPPAY-LINRMPSHEARNYIQSLTQMPKMNFANVFIGA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB6 NRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAA
: : :.:::.:.: : ..:.:: .:. : :: ...: ::
NP_001 N-----PLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDL
280 290 300 310 320 330
350
pF1KB6 R
NP_001 LIDEWKSLTYDEVISFVPPPLDQEEMES
340 350 360
350 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:55:26 2016 done: Fri Nov 4 20:55:27 2016
Total Scan time: 6.550 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]