Result of FASTA (omim) for pFN21AE0478
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0478, 375 aa
  1>>>pF1KE0478 375 - 375 aa - 375 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9740+/-0.000345; mu= 14.0259+/- 0.021
 mean_var=94.2465+/-19.355, 0's: 0 Z-trim(116.3): 57  B-trim: 0 in 0/53
 Lambda= 0.132112
 statistics sampled from 27288 (27345) to 27288 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.321), width:  16
 Scan time:  8.910

The best scores are:                                      opt bits E(85289)
NP_001035110 (OMIM: 158120) monocyte differentiati ( 375) 2497 486.1 5.7e-137
NP_000582 (OMIM: 158120) monocyte differentiation  ( 375) 2497 486.1 5.7e-137
NP_001167576 (OMIM: 158120) monocyte differentiati ( 375) 2497 486.1 5.7e-137
NP_001167575 (OMIM: 158120) monocyte differentiati ( 375) 2497 486.1 5.7e-137
XP_016864065 (OMIM: 246300,603028,607948) PREDICTE ( 784)  169 42.6  0.0038
XP_011530518 (OMIM: 246300,603028,607948) PREDICTE ( 784)  169 42.6  0.0038
XP_016864063 (OMIM: 246300,603028,607948) PREDICTE ( 784)  169 42.6  0.0038
XP_016864062 (OMIM: 246300,603028,607948) PREDICTE ( 784)  169 42.6  0.0038
NP_001305724 (OMIM: 246300,603028,607948) toll-lik ( 784)  169 42.6  0.0038
NP_001305725 (OMIM: 246300,603028,607948) toll-lik ( 784)  169 42.6  0.0038
NP_001305716 (OMIM: 246300,603028,607948) toll-lik ( 784)  169 42.6  0.0038
NP_001305722 (OMIM: 246300,603028,607948) toll-lik ( 784)  169 42.6  0.0038
XP_016864064 (OMIM: 246300,603028,607948) PREDICTE ( 784)  169 42.6  0.0038
NP_001305720 (OMIM: 246300,603028,607948) toll-lik ( 784)  169 42.6  0.0038
NP_003255 (OMIM: 246300,603028,607948) toll-like r ( 784)  169 42.6  0.0038
NP_001305718 (OMIM: 246300,603028,607948) toll-lik ( 784)  169 42.6  0.0038
XP_011530517 (OMIM: 246300,603028,607948) PREDICTE ( 784)  169 42.6  0.0038
NP_001305719 (OMIM: 246300,603028,607948) toll-lik ( 784)  169 42.6  0.0038
XP_011512045 (OMIM: 601194,613223) PREDICTED: toll ( 786)  164 41.6  0.0074
XP_011512044 (OMIM: 601194,613223) PREDICTED: toll ( 786)  164 41.6  0.0074
XP_005262719 (OMIM: 601194,613223) PREDICTED: toll ( 786)  164 41.6  0.0074
XP_011512047 (OMIM: 601194,613223) PREDICTED: toll ( 786)  164 41.6  0.0074
XP_011512046 (OMIM: 601194,613223) PREDICTED: toll ( 786)  164 41.6  0.0074
XP_016864060 (OMIM: 601194,613223) PREDICTED: toll ( 786)  164 41.6  0.0074
NP_003254 (OMIM: 601194,613223) toll-like receptor ( 786)  164 41.6  0.0074
XP_016864061 (OMIM: 601194,613223) PREDICTED: toll ( 786)  164 41.6  0.0074


>>NP_001035110 (OMIM: 158120) monocyte differentiation a  (375 aa)
 initn: 2497 init1: 2497 opt: 2497  Z-score: 2580.0  bits: 486.1 E(85289): 5.7e-137
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)

               10        20        30        40        50        60
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
              310       320       330       340       350       360

              370     
pF1KE0 VSGTLVLLQGARGFA
       :::::::::::::::
NP_001 VSGTLVLLQGARGFA
              370     

>>NP_000582 (OMIM: 158120) monocyte differentiation anti  (375 aa)
 initn: 2497 init1: 2497 opt: 2497  Z-score: 2580.0  bits: 486.1 E(85289): 5.7e-137
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)

               10        20        30        40        50        60
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
              310       320       330       340       350       360

              370     
pF1KE0 VSGTLVLLQGARGFA
       :::::::::::::::
NP_000 VSGTLVLLQGARGFA
              370     

>>NP_001167576 (OMIM: 158120) monocyte differentiation a  (375 aa)
 initn: 2497 init1: 2497 opt: 2497  Z-score: 2580.0  bits: 486.1 E(85289): 5.7e-137
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)

               10        20        30        40        50        60
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
              310       320       330       340       350       360

              370     
pF1KE0 VSGTLVLLQGARGFA
       :::::::::::::::
NP_001 VSGTLVLLQGARGFA
              370     

>>NP_001167575 (OMIM: 158120) monocyte differentiation a  (375 aa)
 initn: 2497 init1: 2497 opt: 2497  Z-score: 2580.0  bits: 486.1 E(85289): 5.7e-137
Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375)

               10        20        30        40        50        60
pF1KE0 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVG
              310       320       330       340       350       360

              370     
pF1KE0 VSGTLVLLQGARGFA
       :::::::::::::::
NP_001 VSGTLVLLQGARGFA
              370     

>>XP_016864065 (OMIM: 246300,603028,607948) PREDICTED: t  (784 aa)
 initn:  97 init1:  97 opt: 169  Z-score: 177.5  bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)

                       10        20        30        40        50  
pF1KE0         MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
                                     :  :.:  :..        .:   ...: :
XP_016 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
        150       160       170       180             190       200

             60                 70        80        90          100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
       : . ....   : :: :         :.  :.: :  ....   .     ....:   ..
XP_016 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
              210       220       230       240       250       260

              110        120       130       140           150     
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
       .  . :  ....:   : : :: ..:  ..:.      .   .     . .: .: .   
XP_016 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
              270       280       290       300       310          

         160        170       180         190       200       210  
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
         : .:  .:.   .   .:  :.  .: .:   :   . . .:  ::::.:  . :. :
XP_016 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
      320       330       340       350       360       370        

            220       230       240       250       260       270  
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
         . :   .:..:.: ::.. . .   .  .: .   .  ..:.:.::..     : :. 
XP_016 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
       380       390       400       410        420            430 

             280       290       300       310       320       330 
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
       :.:   .. :::: . ...:   .:  :..::.: : ::      .::.. .: .. : .
XP_016 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
             440       450       460       470         480         

              340       350       360       370                    
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA               
       . .: ..:                                                    
XP_016 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
     490       500       510       520       530       540         

>>XP_011530518 (OMIM: 246300,603028,607948) PREDICTED: t  (784 aa)
 initn:  97 init1:  97 opt: 169  Z-score: 177.5  bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)

                       10        20        30        40        50  
pF1KE0         MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
                                     :  :.:  :..        .:   ...: :
XP_011 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
        150       160       170       180             190       200

             60                 70        80        90          100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
       : . ....   : :: :         :.  :.: :  ....   .     ....:   ..
XP_011 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
              210       220       230       240       250       260

              110        120       130       140           150     
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
       .  . :  ....:   : : :: ..:  ..:.      .   .     . .: .: .   
XP_011 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
              270       280       290       300       310          

         160        170       180         190       200       210  
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
         : .:  .:.   .   .:  :.  .: .:   :   . . .:  ::::.:  . :. :
XP_011 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
      320       330       340       350       360       370        

            220       230       240       250       260       270  
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
         . :   .:..:.: ::.. . .   .  .: .   .  ..:.:.::..     : :. 
XP_011 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
       380       390       400       410        420            430 

             280       290       300       310       320       330 
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
       :.:   .. :::: . ...:   .:  :..::.: : ::      .::.. .: .. : .
XP_011 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
             440       450       460       470         480         

              340       350       360       370                    
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA               
       . .: ..:                                                    
XP_011 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
     490       500       510       520       530       540         

>>XP_016864063 (OMIM: 246300,603028,607948) PREDICTED: t  (784 aa)
 initn:  97 init1:  97 opt: 169  Z-score: 177.5  bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)

                       10        20        30        40        50  
pF1KE0         MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
                                     :  :.:  :..        .:   ...: :
XP_016 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
        150       160       170       180             190       200

             60                 70        80        90          100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
       : . ....   : :: :         :.  :.: :  ....   .     ....:   ..
XP_016 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
              210       220       230       240       250       260

              110        120       130       140           150     
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
       .  . :  ....:   : : :: ..:  ..:.      .   .     . .: .: .   
XP_016 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
              270       280       290       300       310          

         160        170       180         190       200       210  
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
         : .:  .:.   .   .:  :.  .: .:   :   . . .:  ::::.:  . :. :
XP_016 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
      320       330       340       350       360       370        

            220       230       240       250       260       270  
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
         . :   .:..:.: ::.. . .   .  .: .   .  ..:.:.::..     : :. 
XP_016 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
       380       390       400       410        420            430 

             280       290       300       310       320       330 
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
       :.:   .. :::: . ...:   .:  :..::.: : ::      .::.. .: .. : .
XP_016 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
             440       450       460       470         480         

              340       350       360       370                    
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA               
       . .: ..:                                                    
XP_016 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
     490       500       510       520       530       540         

>>XP_016864062 (OMIM: 246300,603028,607948) PREDICTED: t  (784 aa)
 initn:  97 init1:  97 opt: 169  Z-score: 177.5  bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)

                       10        20        30        40        50  
pF1KE0         MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
                                     :  :.:  :..        .:   ...: :
XP_016 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
        150       160       170       180             190       200

             60                 70        80        90          100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
       : . ....   : :: :         :.  :.: :  ....   .     ....:   ..
XP_016 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
              210       220       230       240       250       260

              110        120       130       140           150     
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
       .  . :  ....:   : : :: ..:  ..:.      .   .     . .: .: .   
XP_016 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
              270       280       290       300       310          

         160        170       180         190       200       210  
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
         : .:  .:.   .   .:  :.  .: .:   :   . . .:  ::::.:  . :. :
XP_016 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
      320       330       340       350       360       370        

            220       230       240       250       260       270  
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
         . :   .:..:.: ::.. . .   .  .: .   .  ..:.:.::..     : :. 
XP_016 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
       380       390       400       410        420            430 

             280       290       300       310       320       330 
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
       :.:   .. :::: . ...:   .:  :..::.: : ::      .::.. .: .. : .
XP_016 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
             440       450       460       470         480         

              340       350       360       370                    
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA               
       . .: ..:                                                    
XP_016 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
     490       500       510       520       530       540         

>>NP_001305724 (OMIM: 246300,603028,607948) toll-like re  (784 aa)
 initn:  97 init1:  97 opt: 169  Z-score: 177.5  bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)

                       10        20        30        40        50  
pF1KE0         MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
                                     :  :.:  :..        .:   ...: :
NP_001 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
        150       160       170       180             190       200

             60                 70        80        90          100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
       : . ....   : :: :         :.  :.: :  ....   .     ....:   ..
NP_001 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
              210       220       230       240       250       260

              110        120       130       140           150     
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
       .  . :  ....:   : : :: ..:  ..:.      .   .     . .: .: .   
NP_001 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
              270       280       290       300       310          

         160        170       180         190       200       210  
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
         : .:  .:.   .   .:  :.  .: .:   :   . . .:  ::::.:  . :. :
NP_001 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
      320       330       340       350       360       370        

            220       230       240       250       260       270  
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
         . :   .:..:.: ::.. . .   .  .: .   .  ..:.:.::..     : :. 
NP_001 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
       380       390       400       410        420            430 

             280       290       300       310       320       330 
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
       :.:   .. :::: . ...:   .:  :..::.: : ::      .::.. .: .. : .
NP_001 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
             440       450       460       470         480         

              340       350       360       370                    
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA               
       . .: ..:                                                    
NP_001 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
     490       500       510       520       530       540         

>>NP_001305725 (OMIM: 246300,603028,607948) toll-like re  (784 aa)
 initn:  97 init1:  97 opt: 169  Z-score: 177.5  bits: 42.6 E(85289): 0.0038
Smith-Waterman score: 170; 22.8% identity (51.8% similar) in 338 aa overlap (23-338:177-497)

                       10        20        30        40        50  
pF1KE0         MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCV
                                     :  :.:  :..        .:   ...: :
NP_001 HLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSY------EPKSLKSIQNV
        150       160       170       180             190       200

             60                 70        80        90          100
pF1KE0 SAVEVEIHAGGLNLEPF---------LKRVDADADPRQYADTVKALR---VRRLTVGAAQ
       : . ....   : :: :         :.  :.: :  ....   .     ....:   ..
NP_001 SHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVK
              210       220       230       240       250       260

              110        120       130       140           150     
pF1KE0 VPAQLLVGALRVLAY-SRLKELTLEDLKITGTMPPLPLEATGLA----LSSLRLRNVSWA
       .  . :  ....:   : : :: ..:  ..:.      .   .     . .: .: .   
NP_001 ITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH--
              270       280       290       300       310          

         160        170       180         190       200       210  
pF1KE0 TGRSWL-AELQQWLKPGLKVLSIAQAHSPAF--SCEQVRAFPALTSLDLSDNPGLGERGL
         : .:  .:.   .   .:  :.  .: .:   :   . . .:  ::::.:  . :. :
NP_001 IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENL-MVEEYL
      320       330       340       350       360       370        

            220       230       240       250       260       270  
pF1KE0 MAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPR-
         . :   .:..:.: ::.. . .   .  .: .   .  ..:.:.::..     : :. 
NP_001 KNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLK-NLTNIDISKNSFH-----SMPET
       380       390       400       410        420            430 

             280       290       300       310       320       330 
pF1KE0 CMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPF
       :.:   .. :::: . ...:   .:  :..::.: : ::      .::.. .: .. : .
NP_001 CQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSL--NLPQLKELYISRNKL
             440       450       460       470         480         

              340       350       360       370                    
pF1KE0 L-VPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA               
       . .: ..:                                                    
NP_001 MTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQ
     490       500       510       520       530       540         




375 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 05:16:40 2016 done: Thu Nov  3 05:16:41 2016
 Total Scan time:  8.910 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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