Result of FASTA (omim) for pFN21AB9540
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9540, 351 aa
  1>>>pF1KB9540 351 - 351 aa - 351 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.0129+/-0.00033; mu= 6.7718+/- 0.021
 mean_var=180.4645+/-35.909, 0's: 0 Z-trim(121.5): 14  B-trim: 1958 in 1/55
 Lambda= 0.095473
 statistics sampled from 38119 (38134) to 38119 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.447), width:  16
 Scan time:  9.880

The best scores are:                                      opt bits E(85289)
NP_001666 (OMIM: 604064) cyclic AMP-dependent tran ( 351) 2337 333.4 4.6e-91
XP_016884296 (OMIM: 604064) PREDICTED: cyclic AMP- ( 351) 2337 333.4 4.6e-91
NP_877962 (OMIM: 604064) cyclic AMP-dependent tran ( 351) 2337 333.4 4.6e-91
NP_036200 (OMIM: 606398) cyclic AMP-dependent tran ( 282)  307 53.7 5.7e-07
NP_001180575 (OMIM: 606398) cyclic AMP-dependent t ( 282)  307 53.7 5.7e-07
XP_011524931 (OMIM: 606398) PREDICTED: cyclic AMP- ( 282)  307 53.7 5.7e-07
NP_001277675 (OMIM: 606398) cyclic AMP-dependent t ( 282)  307 53.7 5.7e-07


>>NP_001666 (OMIM: 604064) cyclic AMP-dependent transcri  (351 aa)
 initn: 2337 init1: 2337 opt: 2337  Z-score: 1755.9  bits: 333.4 E(85289): 4.6e-91
Smith-Waterman score: 2337; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)

               10        20        30        40        50        60
pF1KB9 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 DLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 ELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
              250       260       270       280       290       300

              310       320       330       340       350 
pF1KB9 AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
              310       320       330       340       350 

>>XP_016884296 (OMIM: 604064) PREDICTED: cyclic AMP-depe  (351 aa)
 initn: 2337 init1: 2337 opt: 2337  Z-score: 1755.9  bits: 333.4 E(85289): 4.6e-91
Smith-Waterman score: 2337; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)

               10        20        30        40        50        60
pF1KB9 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 DLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 ELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
              250       260       270       280       290       300

              310       320       330       340       350 
pF1KB9 AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
              310       320       330       340       350 

>>NP_877962 (OMIM: 604064) cyclic AMP-dependent transcri  (351 aa)
 initn: 2337 init1: 2337 opt: 2337  Z-score: 1755.9  bits: 333.4 E(85289): 4.6e-91
Smith-Waterman score: 2337; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)

               10        20        30        40        50        60
pF1KB9 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 DLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 DLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 ELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 ELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
              250       260       270       280       290       300

              310       320       330       340       350 
pF1KB9 AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 AEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
              310       320       330       340       350 

>>NP_036200 (OMIM: 606398) cyclic AMP-dependent transcri  (282 aa)
 initn: 334 init1: 273 opt: 307  Z-score: 246.1  bits: 53.7 E(85289): 5.7e-07
Smith-Waterman score: 336; 33.2% identity (51.5% similar) in 340 aa overlap (12-348:3-278)

               10        20        30        40        50        60
pF1KB9 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
                  :.. :   .:.. : :  .:: : :: ..     :  ..  .. .:. :
NP_036          MSLLATLGLELDRALLPAS-GLGWLVDYGKLPP--APAPLAPYEVLGGALE
                        10         20        30          40        

               70        80        90       100       110       120
pF1KB9 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
            ::   ..    :.::  ::: :..:     . ::: ..    .:   :   . : 
NP_036 ----GGLPVGGEPLAGDGFS--DWMTERVD-----FTALLPLE--PPLPPGTLPQPSPTP
           50        60          70             80          90     

                 130       140       150       160       170       
pF1KB9 -DL--FAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHS
        ::  .: :...  .:  .       ::    .:  . :     ::: .:..  : :  :
NP_036 PDLEAMASLLKKELEQMEDFFLDAPPLPPP--SPPPLPP----PPLPPAPSLPLSLP--S
         100       110       120         130           140         

       180       190       200       210       220       230       
pF1KB9 FSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPS
       :.:     .:        :  :       : .:    .... :  : :   :  ::. : 
NP_036 FDLPQPPVLDTL------DLLAIY-----CRNEA---GQEEVG--MPP---LPPPQQPPP
       150             160            170               180        

       240       250       260       270       280       290       
pF1KB9 TRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQ
          ::    :.:      .:  ::  :      : ..:   :.: :: .:::.:: ::::
NP_036 P--SP----PQP------SRLAPYPHP------ATTRG---DRKQKKRDQNKSAALRYRQ
        190                 200                210       220       

       300       310       320       330       340       350  
pF1KB9 KKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP 
       .:::: ::: :::. :: .:. :::::.:. .::::.:::. :: :::...    
NP_036 RKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC
       230       240       250       260       270       280  

>>NP_001180575 (OMIM: 606398) cyclic AMP-dependent trans  (282 aa)
 initn: 334 init1: 273 opt: 307  Z-score: 246.1  bits: 53.7 E(85289): 5.7e-07
Smith-Waterman score: 336; 33.2% identity (51.5% similar) in 340 aa overlap (12-348:3-278)

               10        20        30        40        50        60
pF1KB9 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
                  :.. :   .:.. : :  .:: : :: ..     :  ..  .. .:. :
NP_001          MSLLATLGLELDRALLPAS-GLGWLVDYGKLPP--APAPLAPYEVLGGALE
                        10         20        30          40        

               70        80        90       100       110       120
pF1KB9 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
            ::   ..    :.::  ::: :..:     . ::: ..    .:   :   . : 
NP_001 ----GGLPVGGEPLAGDGFS--DWMTERVD-----FTALLPLE--PPLPPGTLPQPSPTP
           50        60          70             80          90     

                 130       140       150       160       170       
pF1KB9 -DL--FAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHS
        ::  .: :...  .:  .       ::    .:  . :     ::: .:..  : :  :
NP_001 PDLEAMASLLKKELEQMEDFFLDAPPLPPP--SPPPLPP----PPLPPAPSLPLSLP--S
         100       110       120         130           140         

       180       190       200       210       220       230       
pF1KB9 FSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPS
       :.:     .:        :  :       : .:    .... :  : :   :  ::. : 
NP_001 FDLPQPPVLDTL------DLLAIY-----CRNEA---GQEEVG--MPP---LPPPQQPPP
       150             160            170               180        

       240       250       260       270       280       290       
pF1KB9 TRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQ
          ::    :.:      .:  ::  :      : ..:   :.: :: .:::.:: ::::
NP_001 P--SP----PQP------SRLAPYPHP------ATTRG---DRKQKKRDQNKSAALRYRQ
        190                 200                210       220       

       300       310       320       330       340       350  
pF1KB9 KKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP 
       .:::: ::: :::. :: .:. :::::.:. .::::.:::. :: :::...    
NP_001 RKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC
       230       240       250       260       270       280  

>>XP_011524931 (OMIM: 606398) PREDICTED: cyclic AMP-depe  (282 aa)
 initn: 334 init1: 273 opt: 307  Z-score: 246.1  bits: 53.7 E(85289): 5.7e-07
Smith-Waterman score: 336; 33.2% identity (51.5% similar) in 340 aa overlap (12-348:3-278)

               10        20        30        40        50        60
pF1KB9 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
                  :.. :   .:.. : :  .:: : :: ..     :  ..  .. .:. :
XP_011          MSLLATLGLELDRALLPAS-GLGWLVDYGKLPP--APAPLAPYEVLGGALE
                        10         20        30          40        

               70        80        90       100       110       120
pF1KB9 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
            ::   ..    :.::  ::: :..:     . ::: ..    .:   :   . : 
XP_011 ----GGLPVGGEPLAGDGFS--DWMTERVD-----FTALLPLE--PPLPPGTLPQPSPTP
           50        60          70             80          90     

                 130       140       150       160       170       
pF1KB9 -DL--FAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHS
        ::  .: :...  .:  .       ::    .:  . :     ::: .:..  : :  :
XP_011 PDLEAMASLLKKELEQMEDFFLDAPPLPPP--SPPPLPP----PPLPPAPSLPLSLP--S
         100       110       120         130           140         

       180       190       200       210       220       230       
pF1KB9 FSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPS
       :.:     .:        :  :       : .:    .... :  : :   :  ::. : 
XP_011 FDLPQPPVLDTL------DLLAIY-----CRNEA---GQEEVG--MPP---LPPPQQPPP
       150             160            170               180        

       240       250       260       270       280       290       
pF1KB9 TRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQ
          ::    :.:      .:  ::  :      : ..:   :.: :: .:::.:: ::::
XP_011 P--SP----PQP------SRLAPYPHP------ATTRG---DRKQKKRDQNKSAALRYRQ
        190                 200                210       220       

       300       310       320       330       340       350  
pF1KB9 KKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP 
       .:::: ::: :::. :: .:. :::::.:. .::::.:::. :: :::...    
XP_011 RKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC
       230       240       250       260       270       280  

>>NP_001277675 (OMIM: 606398) cyclic AMP-dependent trans  (282 aa)
 initn: 334 init1: 273 opt: 307  Z-score: 246.1  bits: 53.7 E(85289): 5.7e-07
Smith-Waterman score: 336; 33.2% identity (51.5% similar) in 340 aa overlap (12-348:3-278)

               10        20        30        40        50        60
pF1KB9 MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
                  :.. :   .:.. : :  .:: : :: ..     :  ..  .. .:. :
NP_001          MSLLATLGLELDRALLPAS-GLGWLVDYGKLPP--APAPLAPYEVLGGALE
                        10         20        30          40        

               70        80        90       100       110       120
pF1KB9 WLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTC
            ::   ..    :.::  ::: :..:     . ::: ..    .:   :   . : 
NP_001 ----GGLPVGGEPLAGDGFS--DWMTERVD-----FTALLPLE--PPLPPGTLPQPSPTP
           50        60          70             80          90     

                 130       140       150       160       170       
pF1KB9 -DL--FAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHS
        ::  .: :...  .:  .       ::    .:  . :     ::: .:..  : :  :
NP_001 PDLEAMASLLKKELEQMEDFFLDAPPLPPP--SPPPLPP----PPLPPAPSLPLSLP--S
         100       110       120         130           140         

       180       190       200       210       220       230       
pF1KB9 FSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPS
       :.:     .:        :  :       : .:    .... :  : :   :  ::. : 
NP_001 FDLPQPPVLDTL------DLLAIY-----CRNEA---GQEEVG--MPP---LPPPQQPPP
       150             160            170               180        

       240       250       260       270       280       290       
pF1KB9 TRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQ
          ::    :.:      .:  ::  :      : ..:   :.: :: .:::.:: ::::
NP_001 P--SP----PQP------SRLAPYPHP------ATTRG---DRKQKKRDQNKSAALRYRQ
        190                 200                210       220       

       300       310       320       330       340       350  
pF1KB9 KKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP 
       .:::: ::: :::. :: .:. :::::.:. .::::.:::. :: :::...    
NP_001 RKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC
       230       240       250       260       270       280  




351 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:03:52 2016 done: Sat Nov  5 02:03:53 2016
 Total Scan time:  9.880 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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