Result of FASTA (omim) for
pFN21AB8998
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8998, 412 aa
1>>>pF1KB8998 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8319+/-0.000361; mu= 21.3420+/- 0.023
mean_var=104.2164+/-24.464, 0's: 0 Z-trim(115.4): 490 B-trim: 2784 in 2/49
Lambda= 0.125634
statistics sampled from 25043 (25759) to 25043 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.302), width: 16
Scan time: 8.900
The best scores are: opt bits E(85289)
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 2793 517.0 3.3e-146
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 2793 517.0 3.3e-146
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 2793 517.0 3.3e-146
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 2793 517.0 3.3e-146
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 2793 517.0 3.3e-146
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332) 1274 241.6 2.2e-63
NP_001041695 (OMIM: 102775) adenosine receptor A1 ( 326) 1015 194.6 3e-49
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326) 1015 194.6 3e-49
XP_011521961 (OMIM: 600446) PREDICTED: adenosine r ( 229) 810 157.3 3.6e-38
XP_016879686 (OMIM: 600446) PREDICTED: adenosine r ( 231) 798 155.1 1.7e-37
XP_005244959 (OMIM: 102775) PREDICTED: adenosine r ( 258) 648 128.0 2.7e-29
XP_016855831 (OMIM: 102775) PREDICTED: adenosine r ( 258) 648 128.0 2.7e-29
XP_005244958 (OMIM: 102775) PREDICTED: adenosine r ( 258) 648 128.0 2.7e-29
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 582 116.1 1.2e-25
XP_011521963 (OMIM: 600446) PREDICTED: adenosine r ( 116) 476 96.3 4e-20
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 427 88.1 3.7e-17
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 401 83.4 9.7e-16
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 397 82.7 1.8e-15
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 374 78.5 2.9e-14
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 374 78.5 3e-14
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 374 78.6 3.1e-14
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 374 78.6 3.3e-14
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 374 78.6 3.3e-14
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 374 78.6 3.3e-14
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 374 78.6 3.3e-14
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 374 78.6 3.3e-14
NP_001289608 (OMIM: 600445) adenosine receptor A3 ( 173) 369 77.2 3.5e-14
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 369 77.6 5.4e-14
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 360 76.1 2e-13
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 360 76.2 2.2e-13
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 357 75.5 2.7e-13
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 357 75.5 2.8e-13
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 353 74.7 4e-13
NP_001289607 (OMIM: 600445) adenosine receptor A3 ( 123) 346 72.8 5.2e-13
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 346 73.6 1.2e-12
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 343 72.9 1.5e-12
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 340 72.4 2.2e-12
NP_009158 (OMIM: 604838) probable G-protein couple ( 372) 336 71.6 3.6e-12
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 336 71.7 3.8e-12
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 336 71.7 3.9e-12
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 336 71.8 4.4e-12
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 333 71.1 5.5e-12
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 333 71.2 5.7e-12
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 331 70.8 7e-12
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 331 70.9 7.9e-12
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 331 70.9 8.4e-12
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572) 322 69.3 2.7e-11
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 313 67.5 6.6e-11
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 309 66.8 1.1e-10
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 304 65.8 1.8e-10
>>NP_001265429 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 2793 init1: 2793 opt: 2793 Z-score: 2745.8 bits: 517.0 E(85289): 3.3e-146
Smith-Waterman score: 2793; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB8 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
370 380 390 400 410
>>NP_001265428 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 2793 init1: 2793 opt: 2793 Z-score: 2745.8 bits: 517.0 E(85289): 3.3e-146
Smith-Waterman score: 2793; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB8 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
370 380 390 400 410
>>NP_001265427 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 2793 init1: 2793 opt: 2793 Z-score: 2745.8 bits: 517.0 E(85289): 3.3e-146
Smith-Waterman score: 2793; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB8 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
370 380 390 400 410
>>NP_000666 (OMIM: 102776) adenosine receptor A2a [Homo (412 aa)
initn: 2793 init1: 2793 opt: 2793 Z-score: 2745.8 bits: 517.0 E(85289): 3.3e-146
Smith-Waterman score: 2793; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB8 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
370 380 390 400 410
>>NP_001265426 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 2793 init1: 2793 opt: 2793 Z-score: 2745.8 bits: 517.0 E(85289): 3.3e-146
Smith-Waterman score: 2793; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB8 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
370 380 390 400 410
>>NP_000667 (OMIM: 600446) adenosine receptor A2b [Homo (332 aa)
initn: 1234 init1: 824 opt: 1274 Z-score: 1258.9 bits: 241.6 E(85289): 2.2e-63
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (7-328:8-329)
10 20 30 40 50
pF1KB8 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
..:...::.::.:.. :::::: :: ..::. ::::.:::::::.:::..:
NP_000 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
:::::::: :::. .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_000 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
::.:.::. :::.:.:::::.:::: :: .: .: .. . : : ::::.::
NP_000 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
::.::::::::.::: :::.:: .:..:::.: :::.. : . ...:.:::.:.:::
NP_000 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_000 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
:.:: ::.::: ..: : . :... .: : : :
NP_000 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL
300 310 320 330
360 370 380 390 400 410
pF1KB8 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
>>NP_001041695 (OMIM: 102775) adenosine receptor A1 [Hom (326 aa)
initn: 1007 init1: 700 opt: 1015 Z-score: 1005.3 bits: 194.6 E(85289): 3e-49
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (7-313:10-313)
10 20 30 40 50
pF1KB8 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
..:: .:. ::.... ::::: ::: .:. :...: :.::::.::.:::.
NP_001 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
:.::.:: :. : . : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
:: :: ::.:::..:::::.:::: . ... . . :: . : :: :. :.::
NP_001 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
::::::. :: :::::. .::..: :.::.. : :. .. ::.. :::::.
NP_001 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
190 200 210 220 230
240 250 260 270 280 290
pF1KB8 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
:. :::: ::::::.::.:.:::.: : : : :.:: :.: ::..::..::.::..::
NP_001 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
:: :: .: : :
NP_001 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
300 310 320
>>NP_000665 (OMIM: 102775) adenosine receptor A1 [Homo s (326 aa)
initn: 1007 init1: 700 opt: 1015 Z-score: 1005.3 bits: 194.6 E(85289): 3e-49
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (7-313:10-313)
10 20 30 40 50
pF1KB8 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
..:: .:. ::.... ::::: ::: .:. :...: :.::::.::.:::.
NP_000 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
:.::.:: :. : . : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_000 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
:: :: ::.:::..:::::.:::: . ... . . :: . : :: :. :.::
NP_000 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
::::::. :: :::::. .::..: :.::.. : :. .. ::.. :::::.
NP_000 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
190 200 210 220 230
240 250 260 270 280 290
pF1KB8 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
:. :::: ::::::.::.:.:::.: : : : :.:: :.: ::..::..::.::..::
NP_000 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
:: :: .: : :
NP_000 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
300 310 320
>>XP_011521961 (OMIM: 600446) PREDICTED: adenosine recep (229 aa)
initn: 785 init1: 375 opt: 810 Z-score: 806.2 bits: 157.3 E(85289): 3.6e-38
Smith-Waterman score: 810; 55.5% identity (78.4% similar) in 227 aa overlap (110-328:8-226)
80 90 100 110 120 130
pF1KB8 IACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTP
:::..:::::::.:.::. :::.:.:::::
XP_011 MSERSRTLRYKSLVTGTRARGVIAVLWVLAFGIGLTP
10 20 30
140 150 160 170 180 190
pF1KB8 MLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLL
.:::: :: .: .: .. . : : ::::.::::.::::::::.::: :::.
XP_011 FLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVVPMSYMVYFNFFGCVLPPLLI
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB8 MLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHII
:: .:..:::.: :::.. : . ...:.:::.:.:::::::.:::.:::::::.: .
XP_011 MLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAV
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB8 NCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQ
:: :.: : . .. : : : .::.:::.::::::..:::: :.:: ::.::: ..: :
XP_011 NCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQA
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB8 EPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSA
. :... .: : : :
XP_011 D-VKSGNGQAGVQPALGVGL
220
>>XP_016879686 (OMIM: 600446) PREDICTED: adenosine recep (231 aa)
initn: 765 init1: 355 opt: 798 Z-score: 794.4 bits: 155.1 E(85289): 1.7e-37
Smith-Waterman score: 798; 55.1% identity (78.2% similar) in 225 aa overlap (112-328:12-228)
90 100 110 120 130 140
pF1KB8 CFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPML
:..:::::::.:.::. :::.:.:::::.:
XP_016 MKAAHVVLSAWYKSLVTGTRARGVIAVLWVLAFGIGLTPFL
10 20 30 40
150 160 170 180 190
pF1KB8 GWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLML
::: :: .: .: .. . : : ::::.::::.::::::::.::: :::.::
XP_016 GWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVVPMSYMVYFNFFGCVLPPLLIML
50 60 70 80 90
200 210 220 230 240 250
pF1KB8 GVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINC
.:..:::.: :::.. : . ...:.:::.:.:::::::.:::.:::::::.: .::
XP_016 VIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNC
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB8 FTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEP
:.: : . .. : : : .::.:::.::::::..:::: :.:: ::.::: ..: : .
XP_016 VTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQAD-
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB8 FKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQE
:... .: : : :
XP_016 VKSGNGQAGVQPALGVGL
220 230
412 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:52:50 2016 done: Sat Nov 5 00:52:52 2016
Total Scan time: 8.900 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]