Result of FASTA (omim) for
pFN21AB8532
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8532, 898 aa
1>>>pF1KB8532 898 - 898 aa - 898 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4148+/-0.000475; mu= 4.3463+/- 0.030
mean_var=355.9974+/-73.237, 0's: 0 Z-trim(120.5): 220 B-trim: 1840 in 1/52
Lambda= 0.067975
statistics sampled from 35549 (35814) to 35549 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.42), width: 16
Scan time: 15.680
The best scores are: opt bits E(85289)
XP_016882252 (OMIM: 603182) PREDICTED: interleukin ( 898) 6087 611.9 4.2e-174
NP_060090 (OMIM: 603182) interleukin enhancer-bind ( 898) 6087 611.9 4.2e-174
XP_011526286 (OMIM: 603182) PREDICTED: interleukin ( 898) 6087 611.9 4.2e-174
NP_036350 (OMIM: 603182) interleukin enhancer-bind ( 894) 6044 607.7 7.8e-173
XP_006722805 (OMIM: 603182) PREDICTED: interleukin ( 855) 5522 556.5 2e-157
XP_011526287 (OMIM: 603182) PREDICTED: interleukin ( 777) 4700 475.8 3.4e-133
NP_001131145 (OMIM: 603182) interleukin enhancer-b ( 706) 4606 466.6 1.9e-130
NP_004507 (OMIM: 603182) interleukin enhancer-bind ( 702) 4563 462.4 3.5e-129
NP_703194 (OMIM: 603182) interleukin enhancer-bind ( 690) 4547 460.8 1e-128
XP_016882253 (OMIM: 603182) PREDICTED: interleukin ( 633) 4354 441.8 4.9e-123
XP_011526289 (OMIM: 603182) PREDICTED: interleukin ( 563) 3887 395.9 2.8e-109
XP_016882254 (OMIM: 603182) PREDICTED: interleukin ( 563) 3887 395.9 2.8e-109
XP_016870387 (OMIM: 611138) PREDICTED: spermatid p ( 648) 1979 208.9 6.4e-53
XP_016870386 (OMIM: 611138) PREDICTED: spermatid p ( 657) 1979 208.9 6.5e-53
XP_016870385 (OMIM: 611138) PREDICTED: spermatid p ( 672) 1979 208.9 6.6e-53
XP_016870383 (OMIM: 611138) PREDICTED: spermatid p ( 672) 1979 208.9 6.6e-53
XP_016870384 (OMIM: 611138) PREDICTED: spermatid p ( 672) 1979 208.9 6.6e-53
NP_060857 (OMIM: 611138) spermatid perinuclear RNA ( 672) 1979 208.9 6.6e-53
XP_016870380 (OMIM: 611138) PREDICTED: spermatid p ( 674) 1979 208.9 6.6e-53
XP_016870382 (OMIM: 611138) PREDICTED: spermatid p ( 674) 1979 208.9 6.6e-53
XP_016870381 (OMIM: 611138) PREDICTED: spermatid p ( 674) 1979 208.9 6.6e-53
XP_016870379 (OMIM: 611138) PREDICTED: spermatid p ( 674) 1979 208.9 6.6e-53
NP_001164608 (OMIM: 611138) spermatid perinuclear ( 658) 1907 201.9 8.7e-51
NP_057191 (OMIM: 615635) zinc finger RNA-binding p (1074) 1077 120.7 3.8e-26
NP_001164408 (OMIM: 137070,608030,614782) RNA-bind ( 522) 374 51.4 1.3e-05
NP_004951 (OMIM: 137070,608030,614782) RNA-binding ( 526) 370 51.0 1.8e-05
NP_001164105 (OMIM: 137070,608030,614782) RNA-bind ( 525) 367 50.7 2.2e-05
XP_011507833 (OMIM: 616284) PREDICTED: filaggrin-2 (2239) 358 50.6 0.0001
XP_016883742 (OMIM: 601218) PREDICTED: double-stra ( 723) 345 48.7 0.00012
XP_016883741 (OMIM: 601218) PREDICTED: double-stra ( 733) 345 48.7 0.00012
XP_016883734 (OMIM: 601218) PREDICTED: double-stra ( 750) 345 48.7 0.00012
XP_016883733 (OMIM: 601218) PREDICTED: double-stra ( 763) 345 48.7 0.00012
XP_016883731 (OMIM: 601218) PREDICTED: double-stra ( 790) 345 48.8 0.00013
XP_016883745 (OMIM: 601218) PREDICTED: double-stra ( 674) 343 48.5 0.00013
NP_001153702 (OMIM: 601218) double-stranded RNA-sp ( 674) 343 48.5 0.00013
NP_001103 (OMIM: 601218) double-stranded RNA-speci ( 701) 343 48.5 0.00013
XP_016883744 (OMIM: 601218) PREDICTED: double-stra ( 701) 343 48.5 0.00013
NP_056649 (OMIM: 601218) double-stranded RNA-speci ( 714) 343 48.5 0.00014
XP_016883743 (OMIM: 601218) PREDICTED: double-stra ( 714) 343 48.5 0.00014
NP_056648 (OMIM: 601218) double-stranded RNA-speci ( 741) 343 48.5 0.00014
XP_016883739 (OMIM: 601218) PREDICTED: double-stra ( 741) 343 48.5 0.00014
XP_016883738 (OMIM: 601218) PREDICTED: double-stra ( 741) 343 48.5 0.00014
XP_016883740 (OMIM: 601218) PREDICTED: double-stra ( 741) 343 48.5 0.00014
XP_016883737 (OMIM: 601218) PREDICTED: double-stra ( 741) 343 48.5 0.00014
XP_016883736 (OMIM: 601218) PREDICTED: double-stra ( 741) 343 48.5 0.00014
XP_016883735 (OMIM: 601218) PREDICTED: double-stra ( 742) 343 48.5 0.00014
XP_016883732 (OMIM: 601218) PREDICTED: double-stra ( 769) 343 48.6 0.00014
XP_006724017 (OMIM: 601218) PREDICTED: double-stra ( 769) 343 48.6 0.00014
XP_011527727 (OMIM: 601218) PREDICTED: double-stra ( 772) 343 48.6 0.00014
NP_001254738 (OMIM: 603181) interleukin enhancer-b ( 352) 326 46.5 0.00027
>>XP_016882252 (OMIM: 603182) PREDICTED: interleukin enh (898 aa)
initn: 6087 init1: 6087 opt: 6087 Z-score: 3246.6 bits: 611.9 E(85289): 4.2e-174
Smith-Waterman score: 6087; 100.0% identity (100.0% similar) in 898 aa overlap (1-898:1-898)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
790 800 810 820 830 840
850 860 870 880 890
pF1KB8 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
850 860 870 880 890
>>NP_060090 (OMIM: 603182) interleukin enhancer-binding (898 aa)
initn: 6087 init1: 6087 opt: 6087 Z-score: 3246.6 bits: 611.9 E(85289): 4.2e-174
Smith-Waterman score: 6087; 100.0% identity (100.0% similar) in 898 aa overlap (1-898:1-898)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
790 800 810 820 830 840
850 860 870 880 890
pF1KB8 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
850 860 870 880 890
>>XP_011526286 (OMIM: 603182) PREDICTED: interleukin enh (898 aa)
initn: 6087 init1: 6087 opt: 6087 Z-score: 3246.6 bits: 611.9 E(85289): 4.2e-174
Smith-Waterman score: 6087; 100.0% identity (100.0% similar) in 898 aa overlap (1-898:1-898)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
790 800 810 820 830 840
850 860 870 880 890
pF1KB8 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
850 860 870 880 890
>>NP_036350 (OMIM: 603182) interleukin enhancer-binding (894 aa)
initn: 3505 init1: 3396 opt: 6044 Z-score: 3223.9 bits: 607.7 E(85289): 7.8e-173
Smith-Waterman score: 6044; 99.6% identity (99.6% similar) in 898 aa overlap (1-898:1-894)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
:::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_036 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE----QGPILTKHGKNPVMELNEKR
490 500 510 520 530
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB8 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB8 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
780 790 800 810 820 830
850 860 870 880 890
pF1KB8 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
840 850 860 870 880 890
>>XP_006722805 (OMIM: 603182) PREDICTED: interleukin enh (855 aa)
initn: 5644 init1: 5466 opt: 5522 Z-score: 2947.4 bits: 556.5 E(85289): 2e-157
Smith-Waterman score: 5675; 95.1% identity (95.1% similar) in 898 aa overlap (1-898:1-855)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
:::::::::::::::::::::::::::::::
XP_006 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFR----------------------------
790 800 810
850 860 870 880 890
pF1KB8 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
:::::::::::::::::::::::::::::::::::::::::::
XP_006 ---------------GYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
820 830 840 850
>>XP_011526287 (OMIM: 603182) PREDICTED: interleukin enh (777 aa)
initn: 4754 init1: 4626 opt: 4700 Z-score: 2512.3 bits: 475.8 E(85289): 3.4e-133
Smith-Waterman score: 4951; 86.5% identity (86.5% similar) in 898 aa overlap (1-898:1-777)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
::::::::::::::::::::::::::::::
XP_011 FGGANHGGYMNAGAGYGSYGYGGNSATAGY------------------------------
670 680 690
730 740 750 760 770 780
pF1KB8 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
XP_011 ------------------------------------------------------------
790 800 810 820 830 840
pF1KB8 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY
:::::::::::::::::::::::::::::
XP_011 -------------------------------NYSGSGGRSGGNSYGSGGASYNPGSHGGY
700 710
850 860 870 880 890
pF1KB8 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
720 730 740 750 760 770
>>NP_001131145 (OMIM: 603182) interleukin enhancer-bindi (706 aa)
initn: 4962 init1: 4603 opt: 4606 Z-score: 2462.9 bits: 466.6 E(85289): 1.9e-130
Smith-Waterman score: 4606; 98.4% identity (99.4% similar) in 706 aa overlap (1-704:1-706)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
610 620 630 640 650 660
670 680 690 700 710
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSN--GGHSGNASGGGGGGGGGSSGYG
:::::::::::::::::::::::::::::::.:... : :. ..:
NP_001 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSDFFTDCYGYHDFGSS
670 680 690 700
720 730 740 750 760 770
pF1KB8 SYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQ
>>NP_004507 (OMIM: 603182) interleukin enhancer-binding (702 aa)
initn: 4722 init1: 3379 opt: 4563 Z-score: 2440.2 bits: 462.4 E(85289): 3.5e-129
Smith-Waterman score: 4563; 97.9% identity (98.9% similar) in 706 aa overlap (1-704:1-702)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
:::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_004 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE----QGPILTKHGKNPVMELNEKR
490 500 510 520 530
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
600 610 620 630 640 650
670 680 690 700 710
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSN--GGHSGNASGGGGGGGGGSSGYG
:::::::::::::::::::::::::::::::.:... : :. ..:
NP_004 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSDFFTDCYGYHDFGSS
660 670 680 690 700
720 730 740 750 760 770
pF1KB8 SYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQ
>>NP_703194 (OMIM: 603182) interleukin enhancer-binding (690 aa)
initn: 4740 init1: 3379 opt: 4547 Z-score: 2431.8 bits: 460.8 E(85289): 1e-128
Smith-Waterman score: 4547; 99.1% identity (99.3% similar) in 693 aa overlap (1-693:1-689)
10 20 30 40 50 60
pF1KB8 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR
:::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_703 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE----QGPILTKHGKNPVMELNEKR
490 500 510 520 530
550 560 570 580 590 600
pF1KB8 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB8 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB8 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY
::::::::::::::::::::::::::::::. :
NP_703 FGGANHGGYMNAGAGYGSYGYGGNSATAGYTGFV
660 670 680 690
730 740 750 760 770 780
pF1KB8 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG
>>XP_016882253 (OMIM: 603182) PREDICTED: interleukin enh (633 aa)
initn: 4354 init1: 4354 opt: 4354 Z-score: 2329.9 bits: 441.8 E(85289): 4.9e-123
Smith-Waterman score: 4354; 100.0% identity (100.0% similar) in 633 aa overlap (266-898:1-633)
240 250 260 270 280 290
pF1KB8 LCTRVPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPC
::::::::::::::::::::::::::::::
XP_016 MGAGEALRRVLECLASGIVMPDGSGIYDPC
10 20 30
300 310 320 330 340 350
pF1KB8 EKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDY
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB8 TVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPG
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB8 LQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRD
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB8 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVME
220 230 240 250 260 270
540 550 560 570 580 590
pF1KB8 LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPD
280 290 300 310 320 330
600 610 620 630 640 650
pF1KB8 TPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGR
340 350 360 370 380 390
660 670 680 690 700 710
pF1KB8 GRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSS
400 410 420 430 440 450
720 730 740 750 760 770
pF1KB8 GYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQ
460 470 480 490 500 510
780 790 800 810 820 830
pF1KB8 GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPG
520 530 540 550 560 570
840 850 860 870 880 890
pF1KB8 SHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNY
580 590 600 610 620 630
pF1KB8 QYR
:::
XP_016 QYR
898 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:50:35 2016 done: Sat Nov 5 18:50:37 2016
Total Scan time: 15.680 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]