Result of FASTA (ccds) for
pFN21AB6242
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6242, 687 aa
1>>>pF1KB6242 687 - 687 aa - 687 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4914+/-0.00106; mu= 15.2615+/- 0.065
mean_var=114.6137+/-22.350, 0's: 0 Z-trim(107.5): 75 B-trim: 0 in 0/51
Lambda= 0.119800
statistics sampled from 9514 (9589) to 9514 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.295), width: 16
Scan time: 3.940
The best scores are: opt bits E(32554)
CCDS56372.1 PDE4D gene_id:5144|Hs108|chr5 ( 687) 4507 790.4 0
CCDS56371.1 PDE4D gene_id:5144|Hs108|chr5 ( 679) 4337 761.1 0
CCDS47213.1 PDE4D gene_id:5144|Hs108|chr5 ( 809) 4315 757.3 1.9e-218
CCDS56373.1 PDE4D gene_id:5144|Hs108|chr5 ( 745) 4313 756.9 2.3e-218
CCDS54859.1 PDE4D gene_id:5144|Hs108|chr5 ( 748) 4309 756.2 3.7e-218
CCDS54858.1 PDE4D gene_id:5144|Hs108|chr5 ( 673) 4304 755.4 6.2e-218
CCDS56370.1 PDE4D gene_id:5144|Hs108|chr5 ( 507) 3328 586.6 3e-167
CCDS56369.1 PDE4D gene_id:5144|Hs108|chr5 ( 518) 3304 582.4 5.4e-166
CCDS30742.1 PDE4B gene_id:5142|Hs108|chr1 ( 721) 3239 571.3 1.7e-162
CCDS632.1 PDE4B gene_id:5142|Hs108|chr1 ( 736) 3225 568.9 9.2e-162
CCDS12373.1 PDE4C gene_id:5143|Hs108|chr19 ( 712) 3052 539.0 9e-153
CCDS42523.1 PDE4C gene_id:5143|Hs108|chr19 ( 680) 3045 537.8 2e-152
CCDS46016.1 PDE4C gene_id:5143|Hs108|chr19 ( 606) 2926 517.2 2.8e-146
CCDS30743.1 PDE4B gene_id:5142|Hs108|chr1 ( 564) 2720 481.5 1.4e-135
CCDS72802.1 PDE4B gene_id:5142|Hs108|chr1 ( 503) 2506 444.5 1.7e-124
CCDS12238.1 PDE4A gene_id:5141|Hs108|chr19 ( 647) 2207 392.9 7.7e-109
CCDS45963.1 PDE4A gene_id:5141|Hs108|chr19 ( 825) 2203 392.3 1.5e-108
CCDS45962.1 PDE4A gene_id:5141|Hs108|chr19 ( 860) 2203 392.3 1.5e-108
CCDS58649.1 PDE4A gene_id:5141|Hs108|chr19 ( 864) 2203 392.3 1.5e-108
CCDS45961.1 PDE4A gene_id:5141|Hs108|chr19 ( 886) 2203 392.3 1.6e-108
CCDS5175.1 PDE7B gene_id:27115|Hs108|chr6 ( 450) 782 146.5 8e-35
CCDS34901.1 PDE7A gene_id:5150|Hs108|chr8 ( 456) 738 138.9 1.6e-32
CCDS56538.1 PDE7A gene_id:5150|Hs108|chr8 ( 482) 736 138.6 2.1e-32
CCDS34190.1 PDE8B gene_id:8622|Hs108|chr5 ( 830) 618 118.4 4.4e-26
CCDS34192.1 PDE8B gene_id:8622|Hs108|chr5 ( 788) 608 116.6 1.4e-25
CCDS34191.1 PDE8B gene_id:8622|Hs108|chr5 ( 838) 608 116.6 1.5e-25
CCDS34193.1 PDE8B gene_id:8622|Hs108|chr5 ( 865) 608 116.6 1.5e-25
CCDS4037.1 PDE8B gene_id:8622|Hs108|chr5 ( 885) 608 116.6 1.5e-25
CCDS42944.1 PDE9A gene_id:5152|Hs108|chr21 ( 459) 599 114.9 2.7e-25
CCDS74612.1 PDE1A gene_id:5136|Hs108|chr2 ( 501) 594 114.0 5.2e-25
CCDS42947.1 PDE9A gene_id:5152|Hs108|chr21 ( 433) 593 113.8 5.3e-25
CCDS33571.1 PDE9A gene_id:5152|Hs108|chr21 ( 465) 593 113.8 5.6e-25
CCDS42946.1 PDE9A gene_id:5152|Hs108|chr21 ( 466) 593 113.8 5.6e-25
CCDS33570.1 PDE9A gene_id:5152|Hs108|chr21 ( 491) 593 113.9 5.8e-25
CCDS42943.1 PDE9A gene_id:5152|Hs108|chr21 ( 492) 593 113.9 5.8e-25
CCDS42941.1 PDE9A gene_id:5152|Hs108|chr21 ( 507) 593 113.9 6e-25
CCDS42945.1 PDE9A gene_id:5152|Hs108|chr21 ( 526) 593 113.9 6.1e-25
CCDS33568.1 PDE9A gene_id:5152|Hs108|chr21 ( 533) 593 113.9 6.2e-25
CCDS33567.1 PDE9A gene_id:5152|Hs108|chr21 ( 540) 593 113.9 6.3e-25
CCDS42942.1 PDE9A gene_id:5152|Hs108|chr21 ( 552) 593 113.9 6.4e-25
CCDS33569.1 PDE9A gene_id:5152|Hs108|chr21 ( 567) 593 113.9 6.5e-25
CCDS13690.1 PDE9A gene_id:5152|Hs108|chr21 ( 593) 593 113.9 6.7e-25
CCDS33344.1 PDE1A gene_id:5136|Hs108|chr2 ( 535) 591 113.5 7.9e-25
CCDS2285.1 PDE1A gene_id:5136|Hs108|chr2 ( 545) 591 113.5 8e-25
CCDS58741.1 PDE1A gene_id:5136|Hs108|chr2 ( 519) 587 112.8 1.2e-24
CCDS5437.1 PDE1C gene_id:5137|Hs108|chr7 ( 634) 554 107.2 7.6e-23
CCDS55099.1 PDE1C gene_id:5137|Hs108|chr7 ( 709) 554 107.2 8.3e-23
CCDS55100.1 PDE1C gene_id:5137|Hs108|chr7 ( 769) 554 107.3 8.8e-23
CCDS8882.1 PDE1B gene_id:5153|Hs108|chr12 ( 536) 526 102.3 1.9e-21
CCDS4299.1 PDE6A gene_id:5145|Hs108|chr5 ( 860) 522 101.8 4.5e-21
>>CCDS56372.1 PDE4D gene_id:5144|Hs108|chr5 (687 aa)
initn: 4507 init1: 4507 opt: 4507 Z-score: 4215.5 bits: 790.4 E(32554): 0
Smith-Waterman score: 4507; 100.0% identity (100.0% similar) in 687 aa overlap (1-687:1-687)
10 20 30 40 50 60
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
610 620 630 640 650 660
670 680
pF1KB6 QVEEEAVGEEEESQPEACVIDDRSPDT
:::::::::::::::::::::::::::
CCDS56 QVEEEAVGEEEESQPEACVIDDRSPDT
670 680
>>CCDS56371.1 PDE4D gene_id:5144|Hs108|chr5 (679 aa)
initn: 4337 init1: 4337 opt: 4337 Z-score: 4056.8 bits: 761.1 E(32554): 0
Smith-Waterman score: 4337; 98.4% identity (99.1% similar) in 673 aa overlap (15-687:7-679)
10 20 30 40 50 60
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
: .:. : :: ... ::::::::::::::::::::::::::::::
CCDS56 MSIIMKPRSRSTSSLRTAEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANF
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB6 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB6 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB6 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB6 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB6 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB6 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
600 610 620 630 640 650
670 680
pF1KB6 QVEEEAVGEEEESQPEACVIDDRSPDT
:::::::::::::::::::::::::::
CCDS56 QVEEEAVGEEEESQPEACVIDDRSPDT
660 670
>>CCDS47213.1 PDE4D gene_id:5144|Hs108|chr5 (809 aa)
initn: 4304 init1: 4304 opt: 4315 Z-score: 4035.2 bits: 757.3 E(32554): 1.9e-218
Smith-Waterman score: 4315; 98.4% identity (99.1% similar) in 672 aa overlap (20-687:138-809)
10 20 30 40
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYS----FDVDNGTSAGRSPLD
:::. . .:.. :::::::::::::::
CCDS47 GYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLD
110 120 130 140 150 160
50 60 70 80 90 100
pF1KB6 PMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 PMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFA
170 180 190 200 210 220
110 120 130 140 150 160
pF1KB6 QVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 QVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWC
230 240 250 260 270 280
170 180 190 200 210 220
pF1KB6 LDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIP
290 300 310 320 330 340
230 240 250 260 270 280
pF1KB6 SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH
350 360 370 380 390 400
290 300 310 320 330 340
pF1KB6 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
410 420 430 440 450 460
350 360 370 380 390 400
pF1KB6 ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYND
470 480 490 500 510 520
410 420 430 440 450 460
pF1KB6 SSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
530 540 550 560 570 580
470 480 490 500 510 520
pF1KB6 MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGD
590 600 610 620 630 640
530 540 550 560 570 580
pF1KB6 RERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 RERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
650 660 670 680 690 700
590 600 610 620 630 640
pF1KB6 YQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 YQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKT
710 720 730 740 750 760
650 660 670 680
pF1KB6 LCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
::::::::::::::::::::::::::::::::::::::::::
CCDS47 LCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
770 780 790 800
>>CCDS56373.1 PDE4D gene_id:5144|Hs108|chr5 (745 aa)
initn: 4304 init1: 4304 opt: 4313 Z-score: 4033.8 bits: 756.9 E(32554): 2.3e-218
Smith-Waterman score: 4313; 98.1% identity (99.1% similar) in 673 aa overlap (16-687:73-745)
10 20 30 40
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYS-FDVDNGTSAGRSPL
:. .. ::. ... ::::::::::::::
CCDS56 SKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPL
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB6 DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPF
110 120 130 140 150 160
110 120 130 140 150 160
pF1KB6 AQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDW
170 180 190 200 210 220
170 180 190 200 210 220
pF1KB6 CLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 CLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEI
230 240 250 260 270 280
230 240 250 260 270 280
pF1KB6 PSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGL
290 300 310 320 330 340
290 300 310 320 330 340
pF1KB6 HVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 HVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIH
350 360 370 380 390 400
350 360 370 380 390 400
pF1KB6 AADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYN
410 420 430 440 450 460
410 420 430 440 450 460
pF1KB6 DSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLK
470 480 490 500 510 520
470 480 490 500 510 520
pF1KB6 TMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQG
530 540 550 560 570 580
530 540 550 560 570 580
pF1KB6 DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRE
590 600 610 620 630 640
590 600 610 620 630 640
pF1KB6 WYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 WYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSK
650 660 670 680 690 700
650 660 670 680
pF1KB6 TLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
:::::::::::::::::::::::::::::::::::::::::::
CCDS56 TLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
710 720 730 740
>>CCDS54859.1 PDE4D gene_id:5144|Hs108|chr5 (748 aa)
initn: 4309 init1: 4309 opt: 4309 Z-score: 4030.1 bits: 756.2 E(32554): 3.7e-218
Smith-Waterman score: 4309; 99.4% identity (99.8% similar) in 662 aa overlap (26-687:87-748)
10 20 30 40 50
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLI
..: .:::::::::::::::::::::::::
CCDS54 EQADLKSESENIQRPTSLPLKILPLIAITSAESSGFDVDNGTSAGRSPLDPMTSPGSGLI
60 70 80 90 100 110
60 70 80 90 100 110
pF1KB6 LQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVR
120 130 140 150 160 170
120 130 140 150 160 170
pF1KB6 NNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTR
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB6 HSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKK
240 250 260 270 280 290
240 250 260 270 280 290
pF1KB6 KRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGN
300 310 320 330 340 350
300 310 320 330 340 350
pF1KB6 RPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVL
360 370 380 390 400 410
360 370 380 390 400 410
pF1KB6 LSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLA
420 430 440 450 460 470
420 430 440 450 460 470
pF1KB6 VGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSS
480 490 500 510 520 530
480 490 500 510 520 530
pF1KB6 GVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEIS
540 550 560 570 580 590
540 550 560 570 580 590
pF1KB6 PMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPS
600 610 620 630 640 650
600 610 620 630 640 650
pF1KB6 PAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTE
660 670 680 690 700 710
660 670 680
pF1KB6 IPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
::::::::::::::::::::::::::::::::
CCDS54 IPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
720 730 740
>>CCDS54858.1 PDE4D gene_id:5144|Hs108|chr5 (673 aa)
initn: 4304 init1: 4304 opt: 4304 Z-score: 4026.0 bits: 755.4 E(32554): 6.2e-218
Smith-Waterman score: 4304; 100.0% identity (100.0% similar) in 657 aa overlap (31-687:17-673)
10 20 30 40 50 60
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
::::::::::::::::::::::::::::::
CCDS54 MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANF
10 20 30 40
70 80 90 100 110 120
pF1KB6 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB6 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB6 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB6 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB6 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB6 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
590 600 610 620 630 640
670 680
pF1KB6 QVEEEAVGEEEESQPEACVIDDRSPDT
:::::::::::::::::::::::::::
CCDS54 QVEEEAVGEEEESQPEACVIDDRSPDT
650 660 670
>>CCDS56370.1 PDE4D gene_id:5144|Hs108|chr5 (507 aa)
initn: 3328 init1: 3328 opt: 3328 Z-score: 3116.1 bits: 586.6 E(32554): 3e-167
Smith-Waterman score: 3328; 100.0% identity (100.0% similar) in 507 aa overlap (181-687:1-507)
160 170 180 190 200 210
pF1KB6 YQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEF
::::::::::::::::::::::::::::::
CCDS56 MASNKFKRMLNRELTHLSEMSRSGNQVSEF
10 20 30
220 230 240 250 260 270
pF1KB6 ISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQED
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB6 VLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLE
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB6 DHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQ
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB6 FLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 FLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLA
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB6 TDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYR
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB6 QWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB6 DAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDS
400 410 420 430 440 450
640 650 660 670 680
pF1KB6 GSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
460 470 480 490 500
>>CCDS56369.1 PDE4D gene_id:5144|Hs108|chr5 (518 aa)
initn: 3304 init1: 3304 opt: 3304 Z-score: 3093.6 bits: 582.4 E(32554): 5.4e-166
Smith-Waterman score: 3304; 100.0% identity (100.0% similar) in 503 aa overlap (185-687:16-518)
160 170 180 190 200 210
pF1KB6 ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNT
::::::::::::::::::::::::::::::
CCDS56 MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNT
10 20 30 40
220 230 240 250 260 270
pF1KB6 FLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 FLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAK
50 60 70 80 90 100
280 290 300 310 320 330
pF1KB6 ELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
110 120 130 140 150 160
340 350 360 370 380 390
pF1KB6 ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLIN
170 180 190 200 210 220
400 410 420 430 440 450
pF1KB6 TNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMS
230 240 250 260 270 280
460 470 480 490 500 510
pF1KB6 KHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTD
290 300 310 320 330 340
520 530 540 550 560 570
pF1KB6 RIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
350 360 370 380 390 400
580 590 600 610 620 630
pF1KB6 ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQV
410 420 430 440 450 460
640 650 660 670 680
pF1KB6 EEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
470 480 490 500 510
>>CCDS30742.1 PDE4B gene_id:5142|Hs108|chr1 (721 aa)
initn: 2834 init1: 2204 opt: 3239 Z-score: 3030.8 bits: 571.3 E(32554): 1.7e-162
Smith-Waterman score: 3239; 77.8% identity (90.8% similar) in 640 aa overlap (20-655:68-702)
10 20 30 40
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYS-FDVDNGTSAGRSPLDPMT
..: ::. ... :::.:: : :::::::..
CCDS30 NRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQA
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB6 SPGSGLILQANFV-HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQV
: ..::.:.:.: :::::::::::::::::::::.::::::. :. :::::::::::::
CCDS30 SSSAGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQV
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB6 LASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLD
:::::.:::::. ::::. . .:::: .:: ..... ::.::::: :::::::::::
CCDS30 LASLRSVRNNFTILTNLHGTS-NKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLD
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB6 QLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSP
::::.:: .:::::::::::::::::::::::::::::::::.:::::::::..::::::
CCDS30 QLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSP
220 230 240 250 260 270
230 240 250 260 270 280
pF1KB6 TQKEKEKKKRP--MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH
:::..::::. :.::::::::::::::.:.:: ::::.::.:: :::::::.:::::.
CCDS30 TQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN
280 290 300 310 320 330
290 300 310 320 330 340
pF1KB6 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
.: .: : ::::: ::..:::::::::::.: ::.:::.::::::::.::::::..::
CCDS30 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA
340 350 360 370 380 390
350 360 370 380 390 400
pF1KB6 ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYND
:::.::::::::::::.::::::::::::::.::::::::::::::::::::::::::::
CCDS30 ADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYND
400 410 420 430 440 450
410 420 430 440 450 460
pF1KB6 SSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
::::::::::::::::::.::::.::::::::.:::::::.::::::::::.:::::::
CCDS30 ESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKT
460 470 480 490 500 510
470 480 490 500 510 520
pF1KB6 MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGD
::::::::::::::::::.::::::.::::::::::::: :.::::::::::::::.:::
CCDS30 MVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGD
520 530 540 550 560 570
530 540 550 560 570 580
pF1KB6 RERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
.:::::::::::::::.::::::::::::::::::::::::::.::::::::::::::.:
CCDS30 KERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNW
580 590 600 610 620 630
590 600 610 620 630 640
pF1KB6 YQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKT
::: ::::::: :. .. :: :::::::::.:. ::.. : . :..::
CCDS30 YQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEG----EGHSYFSSTKT
640 650 660 670 680 690
650 660 670 680
pF1KB6 LCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
::. : :. .
CCDS30 LCVIDPENRDSLGETDIDIATEDKSPVDT
700 710 720
>>CCDS632.1 PDE4B gene_id:5142|Hs108|chr1 (736 aa)
initn: 2834 init1: 2204 opt: 3225 Z-score: 3017.6 bits: 568.9 E(32554): 9.2e-162
Smith-Waterman score: 3225; 78.8% identity (91.1% similar) in 628 aa overlap (31-655:95-717)
10 20 30 40 50 60
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
:::.:: : :::::::..: ..::.:.:.:
CCDS63 TPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSAGLVLHATF
70 80 90 100 110 120
70 80 90 100 110
pF1KB6 V-HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
:::::::::::::::::::::.::::::. :. ::::::::::::::::::.:::::.
CCDS63 PGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB6 ALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
::::. . .:::: .:: ..... ::.::::: :::::::::::::::.:: .:::
CCDS63 ILTNLHGTS-NKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVS
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB6 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRP-
::::::::::::::::::::::::::::::.:::::::::..:::::::::..::::.
CCDS63 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQ
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB6 -MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRP
:.::::::::::::::.:.:: ::::.::.:: :::::::.:::::..: .: : :::
CCDS63 LMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRP
310 320 330 340 350 360
300 310 320 330 340 350
pF1KB6 LTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLS
:: ::..:::::::::::.: ::.:::.::::::::.::::::..:::::.::::::::
CCDS63 LTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLS
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB6 TPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVG
::::.::::::::::::::.:::::::::::::::::::::::::::: :::::::::::
CCDS63 TPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVG
430 440 450 460 470 480
420 430 440 450 460 470
pF1KB6 FKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGV
:::::::.::::.::::::::.:::::::.::::::::::.:::::::::::::::::::
CCDS63 FKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGV
490 500 510 520 530 540
480 490 500 510 520 530
pF1KB6 LLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPM
::::::.::::::.::::::::::::: :.::::::::::::::.:::.:::::::::::
CCDS63 LLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPM
550 560 570 580 590 600
540 550 560 570 580 590
pF1KB6 CDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPA
::::.::::::::::::::::::::::::::.::::::::::::::.:::: :::::::
CCDS63 CDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPP
610 620 630 640 650 660
600 610 620 630 640 650
pF1KB6 PDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIP
:. .. :: :::::::::.:. ::.. : . :..::::. : :. .
CCDS63 LDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEG----EGHSYFSSTKTLCVIDPENRDSL
670 680 690 700 710
660 670 680
pF1KB6 LDEQVEEEAVGEEEESQPEACVIDDRSPDT
CCDS63 GETDIDIATEDKSPVDT
720 730
687 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:42:43 2016 done: Sat Nov 5 18:42:44 2016
Total Scan time: 3.940 Total Display time: 0.210
Function used was FASTA [36.3.4 Apr, 2011]