Result of FASTA (omim) for
pFN21AB7602
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7602, 354 aa
1>>>pF1KB7602 354 - 354 aa - 354 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6996+/-0.000438; mu= -11.2294+/- 0.028
mean_var=436.7774+/-89.347, 0's: 0 Z-trim(122.9): 129 B-trim: 0 in 0/57
Lambda= 0.061368
statistics sampled from 41770 (41917) to 41770 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.491), width: 16
Scan time: 9.360
The best scores are: opt bits E(85289)
NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354) 2431 228.9 1.3e-59
NP_001186699 (OMIM: 600036) homeobox protein OTX1 ( 354) 2431 228.9 1.3e-59
NP_758840 (OMIM: 600037,610125,613986) homeobox pr ( 289) 784 83.0 8.8e-16
NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289) 784 83.0 8.8e-16
NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289) 784 83.0 8.8e-16
NP_001257454 (OMIM: 600037,610125,613986) homeobox ( 297) 758 80.7 4.4e-15
NP_068374 (OMIM: 600037,610125,613986) homeobox pr ( 297) 758 80.7 4.4e-15
NP_000545 (OMIM: 120970,268000,602225,613829) cone ( 299) 572 64.3 4e-10
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 347 44.4 0.00041
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 342 44.0 0.00058
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302) 340 43.7 0.00062
NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 347 44.6 0.00063
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 336 43.4 0.00076
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 329 42.7 0.0011
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 319 41.9 0.0025
XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377) 316 41.7 0.0032
XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377) 316 41.7 0.0032
NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377) 316 41.7 0.0032
NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 309 40.9 0.0037
NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382) 313 41.5 0.0038
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 299 39.9 0.0056
NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314) 300 40.2 0.0074
>>NP_055377 (OMIM: 600036) homeobox protein OTX1 [Homo s (354 aa)
initn: 2431 init1: 2431 opt: 2431 Z-score: 1191.3 bits: 228.9 E(85289): 1.3e-59
Smith-Waterman score: 2431; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
310 320 330 340 350
>>NP_001186699 (OMIM: 600036) homeobox protein OTX1 [Hom (354 aa)
initn: 2431 init1: 2431 opt: 2431 Z-score: 1191.3 bits: 228.9 E(85289): 1.3e-59
Smith-Waterman score: 2431; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
310 320 330 340 350
>>NP_758840 (OMIM: 600037,610125,613986) homeobox protei (289 aa)
initn: 893 init1: 619 opt: 784 Z-score: 404.3 bits: 83.0 E(85289): 8.8e-16
Smith-Waterman score: 1133; 57.6% identity (70.5% similar) in 363 aa overlap (1-354:1-289)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
::::::::::..:::.:. .::::::::::::::::::::::::::.::::::::::::
NP_758 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAKKKSSPVRE
:::::::::::::::::::::::::::::::::::::: .:. .: ::::::.::.::
NP_758 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 -SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSI
:: : .::::::: :..: . .:::: :: ::
NP_758 VSSESGTSGQFTPP----SSTSVPTIASSSA-------------PV------------SI
130 140 150
180 190 200 210 220 230
pF1KB7 WSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYP
:::::::: : : :.: .:::::: :::.: :...:.:::
NP_758 WSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQASGYSQGY-
160 170 180
240 250 260 270 280 290
pF1KB7 TPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHPLSQSSGHH
. :.:::::.::.:::.::: :. : ::::. .....: .. : : :.
NP_758 AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPA-----SLST---
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB7 HHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQ-ASWRF
::::.:.:.:::. ::::::. :. ::::::. :::::::: .::.:
NP_758 --------QGYGASSLGFNSTTDCLDYKDQTAS-----WKLNFNA-DCLDYKDQTSSWKF
250 260 270 280
pF1KB7 QVL
:::
NP_758 QVL
>>NP_001257452 (OMIM: 600037,610125,613986) homeobox pro (289 aa)
initn: 893 init1: 619 opt: 784 Z-score: 404.3 bits: 83.0 E(85289): 8.8e-16
Smith-Waterman score: 1133; 57.6% identity (70.5% similar) in 363 aa overlap (1-354:1-289)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
::::::::::..:::.:. .::::::::::::::::::::::::::.::::::::::::
NP_001 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAKKKSSPVRE
:::::::::::::::::::::::::::::::::::::: .:. .: ::::::.::.::
NP_001 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 -SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSI
:: : .::::::: :..: . .:::: :: ::
NP_001 VSSESGTSGQFTPP----SSTSVPTIASSSA-------------PV------------SI
130 140 150
180 190 200 210 220 230
pF1KB7 WSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYP
:::::::: : : :.: .:::::: :::.: :...:.:::
NP_001 WSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQASGYSQGY-
160 170 180
240 250 260 270 280 290
pF1KB7 TPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHPLSQSSGHH
. :.:::::.::.:::.::: :. : ::::. .....: .. : : :.
NP_001 AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPA-----SLST---
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB7 HHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQ-ASWRF
::::.:.:.:::. ::::::. :. ::::::. :::::::: .::.:
NP_001 --------QGYGASSLGFNSTTDCLDYKDQTAS-----WKLNFNA-DCLDYKDQTSSWKF
250 260 270 280
pF1KB7 QVL
:::
NP_001 QVL
>>NP_001257453 (OMIM: 600037,610125,613986) homeobox pro (289 aa)
initn: 893 init1: 619 opt: 784 Z-score: 404.3 bits: 83.0 E(85289): 8.8e-16
Smith-Waterman score: 1133; 57.6% identity (70.5% similar) in 363 aa overlap (1-354:1-289)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
::::::::::..:::.:. .::::::::::::::::::::::::::.::::::::::::
NP_001 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAKKKSSPVRE
:::::::::::::::::::::::::::::::::::::: .:. .: ::::::.::.::
NP_001 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 -SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSI
:: : .::::::: :..: . .:::: :: ::
NP_001 VSSESGTSGQFTPP----SSTSVPTIASSSA-------------PV------------SI
130 140 150
180 190 200 210 220 230
pF1KB7 WSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYP
:::::::: : : :.: .:::::: :::.: :...:.:::
NP_001 WSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQASGYSQGY-
160 170 180
240 250 260 270 280 290
pF1KB7 TPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHPLSQSSGHH
. :.:::::.::.:::.::: :. : ::::. .....: .. : : :.
NP_001 AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPA-----SLST---
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB7 HHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQ-ASWRF
::::.:.:.:::. ::::::. :. ::::::. :::::::: .::.:
NP_001 --------QGYGASSLGFNSTTDCLDYKDQTAS-----WKLNFNA-DCLDYKDQTSSWKF
250 260 270 280
pF1KB7 QVL
:::
NP_001 QVL
>>NP_001257454 (OMIM: 600037,610125,613986) homeobox pro (297 aa)
initn: 879 init1: 442 opt: 758 Z-score: 391.7 bits: 80.7 E(85289): 4.4e-15
Smith-Waterman score: 1107; 56.3% identity (69.0% similar) in 371 aa overlap (1-354:1-297)
10 20 30 40 50
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYP--------ATPRKQRRERTTFTRSQLDV
::::::::::..:::.:. .::::::::::: :::::::::::::::.::::
NP_001 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
10 20 30 40 50 60
60 70 80 90 100
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAK
:::::::::::::::::::::::::::::::::::::::::::::: .:. .: ::::
NP_001 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 KKSSPVRE-SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL
::.::.:: :: : .::::::: :..: . .:::: ::
NP_001 KKTSPAREVSSESGTSGQFTPP----SSTSVPTIASSSA-------------PV------
130 140 150
170 180 190 200 210 220
pF1KB7 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQG
:::::::::: : : :.: .:::::: :::.: :.
NP_001 ------SIWSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQA
160 170 180 190
230 240 250 260 270 280
pF1KB7 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHP
..:.::: . :.:::::.::.:::.::: :. : ::::. .....: .. :
NP_001 SGYSQGY-AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPA----
200 210 220 230 240
290 300 310 320 330 340
pF1KB7 LSQSSGHHHHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYK
: :. ::::.:.:.:::. ::::::. :. ::::::. ::::::
NP_001 -SLST-----------QGYGASSLGFNSTTDCLDYKDQTAS-----WKLNFNA-DCLDYK
250 260 270 280
350
pF1KB7 DQ-ASWRFQVL
:: .::.::::
NP_001 DQTSSWKFQVL
290
>>NP_068374 (OMIM: 600037,610125,613986) homeobox protei (297 aa)
initn: 879 init1: 442 opt: 758 Z-score: 391.7 bits: 80.7 E(85289): 4.4e-15
Smith-Waterman score: 1107; 56.3% identity (69.0% similar) in 371 aa overlap (1-354:1-297)
10 20 30 40 50
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYP--------ATPRKQRRERTTFTRSQLDV
::::::::::..:::.:. .::::::::::: :::::::::::::::.::::
NP_068 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
10 20 30 40 50 60
60 70 80 90 100
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAK
:::::::::::::::::::::::::::::::::::::::::::::: .:. .: ::::
NP_068 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 KKSSPVRE-SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL
::.::.:: :: : .::::::: :..: . .:::: ::
NP_068 KKTSPAREVSSESGTSGQFTPP----SSTSVPTIASSSA-------------PV------
130 140 150
170 180 190 200 210 220
pF1KB7 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQG
:::::::::: : : :.: .:::::: :::.: :.
NP_068 ------SIWSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQA
160 170 180 190
230 240 250 260 270 280
pF1KB7 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHP
..:.::: . :.:::::.::.:::.::: :. : ::::. .....: .. :
NP_068 SGYSQGY-AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPA----
200 210 220 230 240
290 300 310 320 330 340
pF1KB7 LSQSSGHHHHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYK
: :. ::::.:.:.:::. ::::::. :. ::::::. ::::::
NP_068 -SLST-----------QGYGASSLGFNSTTDCLDYKDQTAS-----WKLNFNA-DCLDYK
250 260 270 280
350
pF1KB7 DQ-ASWRFQVL
:: .::.::::
NP_068 DQTSSWKFQVL
290
>>NP_000545 (OMIM: 120970,268000,602225,613829) cone-rod (299 aa)
initn: 717 init1: 494 opt: 572 Z-score: 302.7 bits: 64.3 E(85289): 4e-10
Smith-Waterman score: 765; 41.4% identity (65.7% similar) in 362 aa overlap (1-354:1-299)
10 20 30 40 50
pF1KB7 MMSYLKQPP-YGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAK
::.:.. : :..:.:.:.::..::.: .: ::..::::::::::::::::. :::::::
NP_000 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPA-KKKSSPVRES
:.:::.. :::::::::::::::::::::::::::::.:. . .. :. . :. :....
NP_000 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 SGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWS
.: : : :... . . :.: .: : .:.:..:....: :::
NP_000 AG-------TSPRPSTDVCPDPLGISDSYSPPL---PGPSGSPTTAVATVS------IWS
130 140 150 160
180 190 200 210 220 230
pF1KB7 PASISPGSAPASVSVPEPLAAPSNTSCMQRS--VAAGAATAAASYPMSYGQGGSY---GQ
::: :: .:: ::. ::.: . ..: : :.:. .... .
NP_000 PASESP--------LPEA----------QRAGLVASGPSLTSAPYAMTYAPASAFCSSPS
170 180 190 200
240 250 260 270 280 290
pF1KB7 GYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPH-AHHPLSQSSGH
.: .::: ::.:.: ::.:: . :::.. :.. : :. : : :.
NP_000 AYGSPSS-YFSGLD--PYLSPMVPQLGGPALSPLSGPSVG------PSLAQSPTSLSG--
210 220 230 240 250
300 310 320 330 340 350
pF1KB7 HHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQ
:.:: :.. .: :..:.: ...::...: : ::::::..:.::
NP_000 ---------QSYG----AYSPVDSLEFKDP-----TGTWKFTYNPMDPLDYKDQSAWKFQ
260 270 280 290
pF1KB7 VL
.:
NP_000 IL
>>NP_003915 (OMIM: 209880,603851,613013) paired mesoderm (314 aa)
initn: 445 init1: 298 opt: 347 Z-score: 194.8 bits: 44.4 E(85289): 0.00041
Smith-Waterman score: 390; 39.0% identity (63.8% similar) in 218 aa overlap (36-220:96-312)
10 20 30 40 50 60
pF1KB7 KQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDI
::::: ::::: .:: :: .::.:.::::
NP_003 SLGTLRDHQSSPYAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDI
70 80 90 100 110 120
70 80 90 100 110
pF1KB7 FMREEVALKINLPESRVQVWFKNRRAKCRQQQQSG-----------SGTKSRPAKKKSSP
. :::.::::.: :.::::::.::::: :.:.... :: :: .. :
NP_003 YTREELALKIDLTEARVQVWFQNRRAKFRKQERAAAAAAAAAKNGSSGKKSDSSRDDESK
130 140 150 160 170 180
120 130 140 150 160
pF1KB7 VRESSGSESSGQFTP---PAVSSSASSSSSASSSSAN-PAAAAAAGLGGNP----VAAAS
.:. .:.: : :. : .:....... : :. :.::. .: ::.: .:::.
NP_003 EAKSTDPDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAA
190 200 210 220 230 240
170 180 190 200 210
pF1KB7 SLSTPAASSIWSPAS------------ISPGSAPASVSVPEPLAAP--SNTSCMQRSVAA
. .. ::.. . :. .:: .: . :.:. :..: : : .:: .:
NP_003 AAAAAAAAAAAAAAAGGLAAAGGPGQGWAPGPGPIT-SIPDSLGGPFASVLSSLQRPNGA
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB7 GAATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSM
:: . .:
NP_003 KAALVKSSMF
310
>>NP_115485 (OMIM: 604529) homeobox protein orthopedia [ (325 aa)
initn: 356 init1: 271 opt: 342 Z-score: 192.2 bits: 44.0 E(85289): 0.00058
Smith-Waterman score: 357; 37.2% identity (59.9% similar) in 242 aa overlap (6-241:82-300)
10 20 30
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPS-VGYPAT
::: : .: :: .:: .:
NP_115 VEGATLLPGEDITTVGSTPASLAVSAKDPDKQP--GPQG----GP-----NPSQAGQQQG
60 70 80 90 100
40 50 60 70 80 90
pF1KB7 PRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCR
.::.:.:: :: .::. :: ::::.:::::::::.::.:.: ::::::::.::::: .
NP_115 QQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWK
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB7 QQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANP---AA
..... . .. :. .: . :: :....:. ..: : :: ::
NP_115 KRKKTTNVFRA-PGTLLPTP--------GLPQFPSAAAAAAAAMGDSLCSFHANDTRWAA
170 180 190 200 210
160 170 180 190 200 210
pF1KB7 AAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVA
:: :.. :. : . . :.:. : :.. : : :... . ::. :: . .: .
NP_115 AAMPGVSQLPLPPALGRQQAMAQSL-SQCSLAAGPPPNSMGLSNSLAG-SNGAGLQSHLY
220 230 240 250 260
220 230 240 250 260
pF1KB7 AGA--ATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAP
: . . :: : . .:: : .:.::
NP_115 QPAFPGMVPASLPGPSNVSGS-PQLCSSPDSSDVWRGTSIASLRRKALEHTVSMSFT
270 280 290 300 310 320
270 280 290 300 310 320
pF1KB7 SSMAGHHHHHPHAHHPLSQSSGHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASS
354 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:27:44 2016 done: Sat Nov 5 18:27:46 2016
Total Scan time: 9.360 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]