Result of FASTA (ccds) for
pFN21AB7602
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7602, 354 aa
1>>>pF1KB7602 354 - 354 aa - 354 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0203+/-0.00107; mu= -7.4999+/- 0.065
mean_var=400.3179+/-82.210, 0's: 0 Z-trim(115.0): 105 B-trim: 0 in 0/52
Lambda= 0.064102
statistics sampled from 15486 (15585) to 15486 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.479), width: 16
Scan time: 3.200
The best scores are: opt bits E(32554)
CCDS1873.1 OTX1 gene_id:5013|Hs108|chr2 ( 354) 2431 238.4 7.2e-63
CCDS41960.1 OTX2 gene_id:5015|Hs108|chr14 ( 289) 784 86.0 4.4e-17
CCDS9728.1 OTX2 gene_id:5015|Hs108|chr14 ( 297) 758 83.6 2.4e-16
CCDS12706.1 CRX gene_id:1406|Hs108|chr19 ( 299) 572 66.4 3.6e-11
>>CCDS1873.1 OTX1 gene_id:5013|Hs108|chr2 (354 aa)
initn: 2431 init1: 2431 opt: 2431 Z-score: 1242.2 bits: 238.4 E(32554): 7.2e-63
Smith-Waterman score: 2431; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 SYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHH
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 HQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
310 320 330 340 350
>>CCDS41960.1 OTX2 gene_id:5015|Hs108|chr14 (289 aa)
initn: 893 init1: 619 opt: 784 Z-score: 420.1 bits: 86.0 E(32554): 4.4e-17
Smith-Waterman score: 1133; 57.6% identity (70.5% similar) in 363 aa overlap (1-354:1-289)
10 20 30 40 50 60
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKT
::::::::::..:::.:. .::::::::::::::::::::::::::.::::::::::::
CCDS41 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKT
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAKKKSSPVRE
:::::::::::::::::::::::::::::::::::::: .:. .: ::::::.::.::
CCDS41 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPARE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 -SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSI
:: : .::::::: :..: . .:::: :: ::
CCDS41 VSSESGTSGQFTPP----SSTSVPTIASSSA-------------PV------------SI
130 140 150
180 190 200 210 220 230
pF1KB7 WSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYP
:::::::: : : :.: .:::::: :::.: :...:.:::
CCDS41 WSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQASGYSQGY-
160 170 180
240 250 260 270 280 290
pF1KB7 TPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHPLSQSSGHH
. :.:::::.::.:::.::: :. : ::::. .....: .. : : :.
CCDS41 AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPA-----SLST---
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB7 HHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQ-ASWRF
::::.:.:.:::. ::::::. :. ::::::. :::::::: .::.:
CCDS41 --------QGYGASSLGFNSTTDCLDYKDQTAS-----WKLNFNA-DCLDYKDQTSSWKF
250 260 270 280
pF1KB7 QVL
:::
CCDS41 QVL
>>CCDS9728.1 OTX2 gene_id:5015|Hs108|chr14 (297 aa)
initn: 879 init1: 442 opt: 758 Z-score: 407.0 bits: 83.6 E(32554): 2.4e-16
Smith-Waterman score: 1107; 56.3% identity (69.0% similar) in 371 aa overlap (1-354:1-297)
10 20 30 40 50
pF1KB7 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYP--------ATPRKQRRERTTFTRSQLDV
::::::::::..:::.:. .::::::::::: :::::::::::::::.::::
CCDS97 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
10 20 30 40 50 60
60 70 80 90 100
pF1KB7 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---SGSGTKSRPAK
:::::::::::::::::::::::::::::::::::::::::::::: .:. .: ::::
CCDS97 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 KKSSPVRE-SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL
::.::.:: :: : .::::::: :..: . .:::: ::
CCDS97 KKTSPAREVSSESGTSGQFTPP----SSTSVPTIASSSA-------------PV------
130 140 150
170 180 190 200 210 220
pF1KB7 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQG
:::::::::: : : :.: .:::::: :::.: :.
CCDS97 ------SIWSPASISPLSDPLSTS----------SSCMQRS-----------YPMTYTQA
160 170 180 190
230 240 250 260 270 280
pF1KB7 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAGHHHHHPHAHHP
..:.::: . :.:::::.::.:::.::: :. : ::::. .....: .. :
CCDS97 SGYSQGY-AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPA----
200 210 220 230 240
290 300 310 320 330 340
pF1KB7 LSQSSGHHHHHHHHHHQGYGGSGLAFNSA-DCLDYKEPGAAAASSAWKLNFNSPDCLDYK
: :. ::::.:.:.:::. ::::::. :. ::::::. ::::::
CCDS97 -SLST-----------QGYGASSLGFNSTTDCLDYKDQTAS-----WKLNFNA-DCLDYK
250 260 270 280
350
pF1KB7 DQ-ASWRFQVL
:: .::.::::
CCDS97 DQTSSWKFQVL
290
>>CCDS12706.1 CRX gene_id:1406|Hs108|chr19 (299 aa)
initn: 717 init1: 494 opt: 572 Z-score: 314.0 bits: 66.4 E(32554): 3.6e-11
Smith-Waterman score: 765; 41.4% identity (65.7% similar) in 362 aa overlap (1-354:1-299)
10 20 30 40 50
pF1KB7 MMSYLKQPP-YGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAK
::.:.. : :..:.:.:.::..::.: .: ::..::::::::::::::::. :::::::
CCDS12 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPA-KKKSSPVRES
:.:::.. :::::::::::::::::::::::::::::.:. . .. :. . :. :....
CCDS12 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 SGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWS
.: : : :... . . :.: .: : .:.:..:....: :::
CCDS12 AG-------TSPRPSTDVCPDPLGISDSYSPPL---PGPSGSPTTAVATVS------IWS
130 140 150 160
180 190 200 210 220 230
pF1KB7 PASISPGSAPASVSVPEPLAAPSNTSCMQRS--VAAGAATAAASYPMSYGQGGSY---GQ
::: :: .:: ::. ::.: . ..: : :.:. .... .
CCDS12 PASESP--------LPEA----------QRAGLVASGPSLTSAPYAMTYAPASAFCSSPS
170 180 190 200
240 250 260 270 280 290
pF1KB7 GYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPH-AHHPLSQSSGH
.: .::: ::.:.: ::.:: . :::.. :.. : :. : : :.
CCDS12 AYGSPSS-YFSGLD--PYLSPMVPQLGGPALSPLSGPSVG------PSLAQSPTSLSG--
210 220 230 240 250
300 310 320 330 340 350
pF1KB7 HHHHHHHHHQGYGGSGLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQ
:.:: :.. .: :..:.: ...::...: : ::::::..:.::
CCDS12 ---------QSYG----AYSPVDSLEFKDP-----TGTWKFTYNPMDPLDYKDQSAWKFQ
260 270 280 290
pF1KB7 VL
.:
CCDS12 IL
354 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:27:44 2016 done: Sat Nov 5 18:27:44 2016
Total Scan time: 3.200 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]