Result of FASTA (omim) for
pFN21AB0994
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0994, 461 aa
1>>>pF1KB0994 461 - 461 aa - 461 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8710+/-0.000345; mu= 16.3634+/- 0.021
mean_var=124.0234+/-25.918, 0's: 0 Z-trim(116.9): 156 B-trim: 119 in 1/52
Lambda= 0.115166
statistics sampled from 28277 (28504) to 28277 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.334), width: 16
Scan time: 9.970
The best scores are: opt bits E(85289)
NP_009005 (OMIM: 605000,615401) coronin-1A [Homo s ( 461) 3136 532.5 9.4e-151
NP_001180262 (OMIM: 605000,615401) coronin-1A [Hom ( 461) 3136 532.5 9.4e-151
XP_011544016 (OMIM: 605000,615401) PREDICTED: coro ( 461) 3136 532.5 9.4e-151
XP_016878374 (OMIM: 605000,615401) PREDICTED: coro ( 463) 2933 498.7 1.3e-140
XP_016878375 (OMIM: 605000,615401) PREDICTED: coro ( 463) 2933 498.7 1.3e-140
NP_065174 (OMIM: 609849) coronin-1B [Homo sapiens] ( 489) 2190 375.3 2e-103
NP_001018080 (OMIM: 609849) coronin-1B [Homo sapie ( 489) 2190 375.3 2e-103
NP_055140 (OMIM: 605269) coronin-1C isoform b [Hom ( 474) 2155 369.5 1.1e-101
XP_016874612 (OMIM: 605269) PREDICTED: coronin-1C ( 474) 2155 369.5 1.1e-101
XP_016874611 (OMIM: 605269) PREDICTED: coronin-1C ( 474) 2155 369.5 1.1e-101
NP_001263400 (OMIM: 605269) coronin-1C isoform b [ ( 474) 2155 369.5 1.1e-101
XP_016874610 (OMIM: 605269) PREDICTED: coronin-1C ( 527) 2155 369.5 1.2e-101
NP_001098707 (OMIM: 605269) coronin-1C isoform a [ ( 527) 2155 369.5 1.2e-101
NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63
NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63
NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63
NP_001177385 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63
NP_006082 (OMIM: 605002) coronin-2B isoform 1 [Hom ( 480) 1381 240.9 5.8e-63
NP_003380 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 1349 235.6 2.5e-61
NP_438171 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 1349 235.6 2.5e-61
XP_011517288 (OMIM: 602159) PREDICTED: coronin-2A ( 525) 1349 235.6 2.5e-61
XP_011536427 (OMIM: 605269) PREDICTED: coronin-1C ( 286) 1046 185.0 2.3e-46
NP_078811 (OMIM: 611668) coronin-7 isoform 1 [Homo ( 925) 740 134.7 1e-30
NP_001188401 (OMIM: 611668) coronin-7 isoform 2 [H ( 907) 648 119.4 4.1e-26
NP_001188402 (OMIM: 611668) coronin-7 isoform 3 [H ( 840) 538 101.1 1.2e-20
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 194 43.5 0.0011
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 194 43.5 0.0011
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 194 43.5 0.0011
XP_016863186 (OMIM: 609005) PREDICTED: WD repeat-c ( 982) 199 44.8 0.0012
NP_115737 (OMIM: 606929) THO complex subunit 3 [Ho ( 351) 192 43.2 0.0014
XP_005262782 (OMIM: 609005) PREDICTED: WD repeat-c (1216) 199 44.9 0.0014
NP_851782 (OMIM: 609005) WD repeat-containing prot (1283) 199 45.0 0.0015
XP_011529884 (OMIM: 609005) PREDICTED: WD repeat-c (1290) 199 45.0 0.0015
XP_016863178 (OMIM: 609005) PREDICTED: WD repeat-c (1307) 199 45.0 0.0015
XP_016863177 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 199 45.0 0.0015
XP_016863175 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 199 45.0 0.0015
NP_733828 (OMIM: 609005) WD repeat-containing prot (1322) 199 45.0 0.0015
NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579) 192 43.4 0.0019
NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504) 190 43.0 0.0022
XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 182 41.4 0.0039
XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353) 182 41.5 0.0044
NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353) 182 41.5 0.0044
NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395) 182 41.6 0.0047
XP_005258020 (OMIM: 610091) PREDICTED: WD repeat a ( 216) 178 40.6 0.005
XP_016879923 (OMIM: 610091) PREDICTED: WD repeat a ( 216) 178 40.6 0.005
NP_004795 (OMIM: 604333) probable cytosolic iron-s ( 339) 178 40.8 0.0068
>>NP_009005 (OMIM: 605000,615401) coronin-1A [Homo sapie (461 aa)
initn: 3136 init1: 3136 opt: 3136 Z-score: 2827.5 bits: 532.5 E(85289): 9.4e-151
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)
10 20 30 40 50 60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
370 380 390 400 410 420
430 440 450 460
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
:::::::::::::::::::::::::::::::::::::::::
NP_009 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
430 440 450 460
>>NP_001180262 (OMIM: 605000,615401) coronin-1A [Homo sa (461 aa)
initn: 3136 init1: 3136 opt: 3136 Z-score: 2827.5 bits: 532.5 E(85289): 9.4e-151
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)
10 20 30 40 50 60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
370 380 390 400 410 420
430 440 450 460
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
:::::::::::::::::::::::::::::::::::::::::
NP_001 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
430 440 450 460
>>XP_011544016 (OMIM: 605000,615401) PREDICTED: coronin- (461 aa)
initn: 3136 init1: 3136 opt: 3136 Z-score: 2827.5 bits: 532.5 E(85289): 9.4e-151
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)
10 20 30 40 50 60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
370 380 390 400 410 420
430 440 450 460
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
:::::::::::::::::::::::::::::::::::::::::
XP_011 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
430 440 450 460
>>XP_016878374 (OMIM: 605000,615401) PREDICTED: coronin- (463 aa)
initn: 2933 init1: 2933 opt: 2933 Z-score: 2645.2 bits: 498.7 E(85289): 1.3e-140
Smith-Waterman score: 2933; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
370 380 390 400 410 420
430 440 450 460
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
:::::::
XP_016 ASGTPSSVRGLGSQGIKLGGWGGAGVWGTSNSQHWESLWVREW
430 440 450 460
>>XP_016878375 (OMIM: 605000,615401) PREDICTED: coronin- (463 aa)
initn: 2933 init1: 2933 opt: 2933 Z-score: 2645.2 bits: 498.7 E(85289): 1.3e-140
Smith-Waterman score: 2933; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
370 380 390 400 410 420
430 440 450 460
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
:::::::
XP_016 ASGTPSSVRGLGSQGIKLGGWGGAGVWGTSNSQHWESLWVREW
430 440 450 460
>>NP_065174 (OMIM: 609849) coronin-1B [Homo sapiens] (489 aa)
initn: 2244 init1: 1235 opt: 2190 Z-score: 1977.7 bits: 375.3 E(85289): 2e-103
Smith-Waterman score: 2217; 66.5% identity (86.2% similar) in 477 aa overlap (3-456:4-479)
10 20 30 40 50
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAF
:.:::.::::::::::.: ::::::.:::..:::: ::::::::.:.: ::::::::
NP_065 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 LVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLP
:::::.::::.:: :::::::.::::: ::::::.::::::::::::::.::..:: :
NP_065 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 LREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTI
: ::::.::::::::::.::: ::.:::::::::::...:.:::. . : .::: :
NP_065 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDS-LHPDLI
130 140 150 160 170
180 190 200 210 220 230
pF1KB0 YSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGF
:.:.:...:.:.:..:.:: ::::.::.::.:::... :::.::.::.:...::..::::
NP_065 YNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 SRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITS
:::::::.:::: ..::::..:::::.:.:.::::.::::..::.::::::::::::::
NP_065 SRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB0 EAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLF
: :..:.:. :.::: ::::: ::::::::.:::::::::::::.::::.::::::::::
NP_065 EPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB0 QEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRA
:.:::: ::::. :: ::::..:::: :.::::...::: :.:.:...: :. .:
NP_065 QDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAM
360 370 380 390 400 410
420 430 440 450
pF1KB0 APEAS--GTPSS-----DAV-----------SRLEE---EMRKLQATVQELQKRLDRLEE
:: .: :.:.: ::. ..::: :.: :.: :.: :. ::::
NP_065 APGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE
420 430 440 450 460 470
460
pF1KB0 TVQAK
NP_065 QLGRMENGDA
480
>>NP_001018080 (OMIM: 609849) coronin-1B [Homo sapiens] (489 aa)
initn: 2244 init1: 1235 opt: 2190 Z-score: 1977.7 bits: 375.3 E(85289): 2e-103
Smith-Waterman score: 2217; 66.5% identity (86.2% similar) in 477 aa overlap (3-456:4-479)
10 20 30 40 50
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAF
:.:::.::::::::::.: ::::::.:::..:::: ::::::::.:.: ::::::::
NP_001 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 LVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLP
:::::.::::.:: :::::::.::::: ::::::.::::::::::::::.::..:: :
NP_001 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 LREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTI
: ::::.::::::::::.::: ::.:::::::::::...:.:::. . : .::: :
NP_001 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDS-LHPDLI
130 140 150 160 170
180 190 200 210 220 230
pF1KB0 YSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGF
:.:.:...:.:.:..:.:: ::::.::.::.:::... :::.::.::.:...::..::::
NP_001 YNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 SRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITS
:::::::.:::: ..::::..:::::.:.:.::::.::::..::.::::::::::::::
NP_001 SRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB0 EAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLF
: :..:.:. :.::: ::::: ::::::::.:::::::::::::.::::.::::::::::
NP_001 EPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB0 QEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRA
:.:::: ::::. :: ::::..:::: :.::::...::: :.:.:...: :. .:
NP_001 QDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAM
360 370 380 390 400 410
420 430 440 450
pF1KB0 APEAS--GTPSS-----DAV-----------SRLEE---EMRKLQATVQELQKRLDRLEE
:: .: :.:.: ::. ..::: :.: :.: :.: :. ::::
NP_001 APGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE
420 430 440 450 460 470
460
pF1KB0 TVQAK
NP_001 QLGRMENGDA
480
>>NP_055140 (OMIM: 605269) coronin-1C isoform b [Homo sa (474 aa)
initn: 2181 init1: 1198 opt: 2155 Z-score: 1946.4 bits: 369.5 E(85289): 1.1e-101
Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467)
10 20 30 40 50 60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
:.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: :::::::::
NP_055 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
:::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : :
NP_055 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
:::: ::::.::::::::: ::.::::::::::.:..:.:::: :...: ..: : ::
NP_055 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
.:.:.:.:.::::. .::.::.:.::: .::::.. :::.::.::.:...:...:::::
NP_055 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.:
NP_055 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
.:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: :::::::::::
NP_055 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
300 310 320 330 340 350
370 380 390 400 410
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR
.:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: . :: :. .
NP_055 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK
360 370 380 390 400 410
420 430 440 450 460
pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK
. . :. .. : : . ..:.: :..... :. . ..:...::.
NP_055 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
420 430 440 450 460 470
>>XP_016874612 (OMIM: 605269) PREDICTED: coronin-1C isof (474 aa)
initn: 2181 init1: 1198 opt: 2155 Z-score: 1946.4 bits: 369.5 E(85289): 1.1e-101
Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467)
10 20 30 40 50 60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
:.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: :::::::::
XP_016 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
:::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : :
XP_016 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
:::: ::::.::::::::: ::.::::::::::.:..:.:::: :...: ..: : ::
XP_016 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
.:.:.:.:.::::. .::.::.:.::: .::::.. :::.::.::.:...:...:::::
XP_016 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.:
XP_016 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
.:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: :::::::::::
XP_016 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
300 310 320 330 340 350
370 380 390 400 410
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR
.:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: . :: :. .
XP_016 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK
360 370 380 390 400 410
420 430 440 450 460
pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK
. . :. .. : : . ..:.: :..... :. . ..:...::.
XP_016 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
420 430 440 450 460 470
>>XP_016874611 (OMIM: 605269) PREDICTED: coronin-1C isof (474 aa)
initn: 2181 init1: 1198 opt: 2155 Z-score: 1946.4 bits: 369.5 E(85289): 1.1e-101
Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467)
10 20 30 40 50 60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
:.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: :::::::::
XP_016 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
:::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : :
XP_016 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
:::: ::::.::::::::: ::.::::::::::.:..:.:::: :...: ..: : ::
XP_016 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
.:.:.:.:.::::. .::.::.:.::: .::::.. :::.::.::.:...:...:::::
XP_016 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.:
XP_016 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
.:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: :::::::::::
XP_016 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
300 310 320 330 340 350
370 380 390 400 410
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR
.:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: . :: :. .
XP_016 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK
360 370 380 390 400 410
420 430 440 450 460
pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK
. . :. .. : : . ..:.: :..... :. . ..:...::.
XP_016 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
420 430 440 450 460 470
461 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:43:32 2016 done: Sat Nov 5 17:43:33 2016
Total Scan time: 9.970 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]