Result of FASTA (omim) for
pFN21AB8560
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8560, 910 aa
1>>>pF1KB8560 910 - 910 aa - 910 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1925+/-0.000404; mu= 21.8786+/- 0.025
mean_var=68.1225+/-13.474, 0's: 0 Z-trim(111.1): 252 B-trim: 58 in 1/53
Lambda= 0.155392
statistics sampled from 19414 (19668) to 19414 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.58), E-opt: 0.2 (0.231), width: 16
Scan time: 13.290
The best scores are: opt bits E(85289)
NP_036547 (OMIM: 604289,605027) DNA repair and rec ( 910) 6121 1382.0 0
NP_001192192 (OMIM: 604289,605027) DNA repair and ( 726) 4889 1105.7 0
NP_003570 (OMIM: 114480,603615,605027) DNA repair ( 747) 1045 244.0 2.1e-63
NP_001136020 (OMIM: 114480,603615,605027) DNA repa ( 747) 1045 244.0 2.1e-63
XP_006711038 (OMIM: 114480,603615,605027) PREDICTE ( 567) 850 200.2 2.4e-50
NP_001192191 (OMIM: 604289,605027) DNA repair and ( 117) 697 165.5 1.4e-40
XP_011540601 (OMIM: 114480,603615,605027) PREDICTE ( 489) 699 166.3 3.3e-40
XP_011540602 (OMIM: 114480,603615,605027) PREDICTE ( 489) 699 166.3 3.3e-40
NP_000115 (OMIM: 133540,211980,214150,278800,60063 (1493) 485 118.6 2.2e-25
NP_001333369 (OMIM: 133540,211980,214150,278800,60 (1493) 485 118.6 2.2e-25
NP_060139 (OMIM: 300687) DNA excision repair prote (1250) 476 116.6 7.9e-25
XP_016872369 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 476 116.6 9.2e-25
XP_016872370 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 476 116.6 9.2e-25
XP_016872368 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 476 116.6 9.2e-25
XP_016885240 (OMIM: 300012) PREDICTED: probable gl (1036) 474 116.1 9.2e-25
XP_016885239 (OMIM: 300012) PREDICTED: probable gl (1042) 474 116.1 9.3e-25
XP_006724845 (OMIM: 300012) PREDICTED: probable gl (1042) 474 116.1 9.3e-25
NP_001269804 (OMIM: 300012) probable global transc (1058) 474 116.1 9.4e-25
XP_016872367 (OMIM: 605191) PREDICTED: TATA-bindin (1646) 476 116.6 9.8e-25
XP_011538630 (OMIM: 605191) PREDICTED: TATA-bindin (1693) 476 116.7 1e-24
XP_011538629 (OMIM: 605191) PREDICTED: TATA-bindin (1725) 476 116.7 1e-24
XP_016872366 (OMIM: 605191) PREDICTED: TATA-bindin (1800) 476 116.7 1.1e-24
XP_011538628 (OMIM: 605191) PREDICTED: TATA-bindin (1812) 476 116.7 1.1e-24
NP_003963 (OMIM: 605191) TATA-binding protein-asso (1849) 476 116.7 1.1e-24
NP_001275998 (OMIM: 603946,616911) lymphoid-specif ( 806) 452 111.1 2.3e-23
XP_011516946 (OMIM: 615667,615715) PREDICTED: DNA (1263) 444 109.4 1.1e-22
NP_003592 (OMIM: 603375) SWI/SNF-related matrix-as (1052) 426 105.3 1.6e-21
NP_001010895 (OMIM: 615667,615715) DNA excision re ( 712) 404 100.3 3.6e-20
XP_011516949 (OMIM: 615667,615715) PREDICTED: DNA (1178) 404 100.4 5.4e-20
XP_011516948 (OMIM: 615667,615715) PREDICTED: DNA (1184) 404 100.4 5.4e-20
XP_011516947 (OMIM: 615667,615715) PREDICTED: DNA (1253) 404 100.4 5.7e-20
XP_011516943 (OMIM: 615667,615715) PREDICTED: DNA (1510) 404 100.5 6.6e-20
NP_064592 (OMIM: 615667,615715) DNA excision repai (1561) 404 100.5 6.8e-20
NP_001276004 (OMIM: 603946,616911) lymphoid-specif ( 432) 391 97.2 1.8e-19
NP_001276003 (OMIM: 603946,616911) lymphoid-specif ( 477) 391 97.2 2e-19
NP_001276002 (OMIM: 603946,616911) lymphoid-specif ( 700) 391 97.4 2.7e-19
NP_001276001 (OMIM: 603946,616911) lymphoid-specif ( 708) 391 97.4 2.7e-19
NP_001276000 (OMIM: 603946,616911) lymphoid-specif ( 714) 391 97.4 2.7e-19
NP_001275999 (OMIM: 603946,616911) lymphoid-specif ( 740) 391 97.4 2.8e-19
NP_001275997 (OMIM: 603946,616911) lymphoid-specif ( 822) 391 97.4 3.1e-19
NP_060533 (OMIM: 603946,616911) lymphoid-specific ( 838) 391 97.4 3.1e-19
XP_016874223 (OMIM: 603277,617159) PREDICTED: chro (1892) 395 98.5 3.2e-19
XP_016874222 (OMIM: 603277,617159) PREDICTED: chro (1893) 395 98.5 3.2e-19
XP_016874221 (OMIM: 603277,617159) PREDICTED: chro (1895) 395 98.5 3.2e-19
XP_016874220 (OMIM: 603277,617159) PREDICTED: chro (1899) 395 98.5 3.2e-19
XP_016874219 (OMIM: 603277,617159) PREDICTED: chro (1900) 395 98.5 3.2e-19
XP_006719025 (OMIM: 603277,617159) PREDICTED: chro (1902) 395 98.5 3.2e-19
XP_005253725 (OMIM: 603277,617159) PREDICTED: chro (1905) 395 98.5 3.2e-19
NP_001284482 (OMIM: 603277,617159) chromodomain-he (1905) 395 98.5 3.2e-19
XP_016874218 (OMIM: 603277,617159) PREDICTED: chro (1906) 395 98.5 3.2e-19
>>NP_036547 (OMIM: 604289,605027) DNA repair and recombi (910 aa)
initn: 6121 init1: 6121 opt: 6121 Z-score: 7408.2 bits: 1382.0 E(85289): 0
Smith-Waterman score: 6121; 100.0% identity (100.0% similar) in 910 aa overlap (1-910:1-910)
10 20 30 40 50 60
pF1KB8 MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 KENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 KNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 ILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 PKIENVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PKIENVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 SIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 EKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 KAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 RQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 SLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIF
850 860 870 880 890 900
910
pF1KB8 QNITTQATGT
::::::::::
NP_036 QNITTQATGT
910
>>NP_001192192 (OMIM: 604289,605027) DNA repair and reco (726 aa)
initn: 4889 init1: 4889 opt: 4889 Z-score: 5916.9 bits: 1105.7 E(85289): 0
Smith-Waterman score: 4889; 100.0% identity (100.0% similar) in 726 aa overlap (185-910:1-726)
160 170 180 190 200 210
pF1KB8 ILKNLEGKDIGRGIGYKFKELEKIEEGQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGS
::::::::::::::::::::::::::::::
NP_001 MICGKEIEVMGVISPDDFSSGRCFQLGGGS
10 20 30
220 230 240 250 260 270
pF1KB8 TAISHSSQVARKCFSNPFKSVCKPSSKENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAISHSSQVARKCFSNPFKSVCKPSSKENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQW
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB8 VFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTL
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB8 QCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKV
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB8 EEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEK
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB8 RIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGER
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB8 RAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLLNSQVVRFCLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLLNSQVVRFCLQG
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB8 LLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPL
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB8 LFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQT
460 470 480 490 500 510
700 710 720 730 740 750
pF1KB8 PISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRV
520 530 540 550 560 570
760 770 780 790 800 810
pF1KB8 WRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFT
580 590 600 610 620 630
820 830 840 850 860 870
pF1KB8 LHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQW
640 650 660 670 680 690
880 890 900 910
pF1KB8 KHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT
::::::::::::::::::::::::::::::::::::
NP_001 KHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT
700 710 720
>>NP_003570 (OMIM: 114480,603615,605027) DNA repair and (747 aa)
initn: 1572 init1: 554 opt: 1045 Z-score: 1259.4 bits: 244.0 E(85289): 2.1e-63
Smith-Waterman score: 1673; 43.1% identity (66.8% similar) in 708 aa overlap (218-901:68-736)
190 200 210 220 230 240
pF1KB8 GKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSSKE---NR
:. :. .:.::: : :. . .:
NP_003 SSETQIQECFLSPFRKPLSQLTNQPPCLDSSQHEAFIRSILSKPFK-VPIPNYQGPLGSR
40 50 60 70 80 90
250 260 270 280 290
pF1KB8 QNDFQNCKPR---HDPYTPNSLVM--PRPDKNH-QWVFNKNCFPLVDVVIDPYLVYHLRP
.. : ::: ..::. : : . : : ..:. .: : ::.:: : :::
NP_003 ALGLKRAGVRRALHDPLEKDALVLYEPPPLSAHDQLKLDKEKLP-VHVVVDPILSKVLRP
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB8 HQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKT
::.::. ::.::: . :. : : :.:::::::::::::.:.::: :.: :: : :.
NP_003 HQREGVKFLWECVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPEC-KPEIDKA
160 170 180 190 200 210
360 370 380 390 400
pF1KB8 LIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQ------DHKVEEFIKS----IFYSVLII
..:.:.:::.:: .: ::::. ::. ...: :.:.: :... . .:::
NP_003 VVVSPSSLVKNWYNEVGKWLGG-RIQPLAIDGGSKDEIDQKLEGFMNQRGARVSSPILII
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB8 SYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQ
::: . . ... . :.::::::::::: .: :: ::. .:....::::::::
NP_003 SYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLL
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB8 EFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFIL
:.:.:. ::: ::::. ..: .: ::. .:. .::: ...:::.: ::: ... ..
NP_003 EYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLI
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB8 RRTQEIINKYLPPKIENVVFCRPGALQIELYRKLL-NSQVVRFCLQGLLENSPHLICIGA
:::..:..:::: :::.:: :: :: :::...: ... .. :.: . : : : .
NP_003 RRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSS-LSSITS
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB8 LKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVL
:::::::: :... .: ::.. . : :..:: :. . . :::. ::
NP_003 LKKLCNHPALIYD-----KCV------EEEDGFVGALDLFPPGYSSKALEPQLSGKMLVL
460 470 480 490 500
650 660 670 680 690 700
pF1KB8 SKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFN
. .::: . : ..::::::::::::......:. . : :.:::: :..: ..:. ::
NP_003 DYILAVTRS-RSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFN
510 520 530 540 550 560
710 720 730 740 750 760
pF1KB8 SQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYR
: : :.:.::::::: ::::::...:...: :::::.: :::.:::::::: .:::
NP_003 SPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYR
570 580 590 600 610 620
770 780 790 800 810 820
pF1KB8 LLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLL
::..:::::::.::: :..: . ::: . :. .::. :::.:: : :.: ::: :
NP_003 LLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVER-HFSLGELKELFILDEASLSDTHDRL
630 640 650 660 670
830 840 850 860 870 880
pF1KB8 DCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDP
:. . . :: :. : . :. :.: :.: . :. .: :
NP_003 HCR-------------RCVNSR--QIRPPPDGSDCT-----SDLAGWNHCT-DKWGLRDE
680 690 700 710
890 900 910
pF1KB8 FLERI----TENVSFIFQNITTQATGT
:. . ..:.:.
NP_003 VLQAAWDAASTAITFVFHQRSHEEQRGLR
720 730 740
>>NP_001136020 (OMIM: 114480,603615,605027) DNA repair a (747 aa)
initn: 1572 init1: 554 opt: 1045 Z-score: 1259.4 bits: 244.0 E(85289): 2.1e-63
Smith-Waterman score: 1673; 43.1% identity (66.8% similar) in 708 aa overlap (218-901:68-736)
190 200 210 220 230 240
pF1KB8 GKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSSKE---NR
:. :. .:.::: : :. . .:
NP_001 SSETQIQECFLSPFRKPLSQLTNQPPCLDSSQHEAFIRSILSKPFK-VPIPNYQGPLGSR
40 50 60 70 80 90
250 260 270 280 290
pF1KB8 QNDFQNCKPR---HDPYTPNSLVM--PRPDKNH-QWVFNKNCFPLVDVVIDPYLVYHLRP
.. : ::: ..::. : : . : : ..:. .: : ::.:: : :::
NP_001 ALGLKRAGVRRALHDPLEKDALVLYEPPPLSAHDQLKLDKEKLP-VHVVVDPILSKVLRP
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB8 HQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKT
::.::. ::.::: . :. : : :.:::::::::::::.:.::: :.: :: : :.
NP_001 HQREGVKFLWECVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPEC-KPEIDKA
160 170 180 190 200 210
360 370 380 390 400
pF1KB8 LIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQ------DHKVEEFIKS----IFYSVLII
..:.:.:::.:: .: ::::. ::. ...: :.:.: :... . .:::
NP_001 VVVSPSSLVKNWYNEVGKWLGG-RIQPLAIDGGSKDEIDQKLEGFMNQRGARVSSPILII
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB8 SYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQ
::: . . ... . :.::::::::::: .: :: ::. .:....::::::::
NP_001 SYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLL
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB8 EFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFIL
:.:.:. ::: ::::. ..: .: ::. .:. .::: ...:::.: ::: ... ..
NP_001 EYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLI
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB8 RRTQEIINKYLPPKIENVVFCRPGALQIELYRKLL-NSQVVRFCLQGLLENSPHLICIGA
:::..:..:::: :::.:: :: :: :::...: ... .. :.: . : : : .
NP_001 RRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSS-LSSITS
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB8 LKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVL
:::::::: :... .: ::.. . : :..:: :. . . :::. ::
NP_001 LKKLCNHPALIYD-----KCV------EEEDGFVGALDLFPPGYSSKALEPQLSGKMLVL
460 470 480 490 500
650 660 670 680 690 700
pF1KB8 SKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFN
. .::: . : ..::::::::::::......:. . : :.:::: :..: ..:. ::
NP_001 DYILAVTRS-RSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFN
510 520 530 540 550 560
710 720 730 740 750 760
pF1KB8 SQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYR
: : :.:.::::::: ::::::...:...: :::::.: :::.:::::::: .:::
NP_001 SPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYR
570 580 590 600 610 620
770 780 790 800 810 820
pF1KB8 LLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLL
::..:::::::.::: :..: . ::: . :. .::. :::.:: : :.: ::: :
NP_001 LLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVER-HFSLGELKELFILDEASLSDTHDRL
630 640 650 660 670
830 840 850 860 870 880
pF1KB8 DCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDP
:. . . :: :. : . :. :.: :.: . :. .: :
NP_001 HCR-------------RCVNSR--QIRPPPDGSDCT-----SDLAGWNHCT-DKWGLRDE
680 690 700 710
890 900 910
pF1KB8 FLERI----TENVSFIFQNITTQATGT
:. . ..:.:.
NP_001 VLQAAWDAASTAITFVFHQRSHEEQRGLR
720 730 740
>>XP_006711038 (OMIM: 114480,603615,605027) PREDICTED: D (567 aa)
initn: 1445 init1: 554 opt: 850 Z-score: 1024.9 bits: 200.2 E(85289): 2.4e-50
Smith-Waterman score: 1478; 44.2% identity (68.6% similar) in 593 aa overlap (324-901:1-556)
300 310 320 330 340 350
pF1KB8 YHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKP
.:::::::::::::.:.::: :.: ::
XP_006 MADEMGLGKTLQCITLMWTLLRQSPEC-KP
10 20
360 370 380 390 400
pF1KB8 VIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQ------DHKVEEFIKS----IFY
: :...:.:.:::.:: .: ::::. ::. ...: :.:.: :... .
XP_006 EIDKAVVVSPSSLVKNWYNEVGKWLGG-RIQPLAIDGGSKDEIDQKLEGFMNQRGARVSS
30 40 50 60 70 80
410 420 430 440 450 460
pF1KB8 SVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPI
.:::::: . . ... . :.::::::::::: .: :: ::. .:....::::
XP_006 PILIISYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPI
90 100 110 120 130 140
470 480 490 500 510 520
pF1KB8 QNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLT
:::: :.:.:. ::: ::::. ..: .: ::. .:. .::: ...:::.: ::: ..
XP_006 QNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIV
150 160 170 180 190 200
530 540 550 560 570 580
pF1KB8 GLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLL-NSQVVRFCLQGLLENSPHL
. ..:::..:..:::: :::.:: :: :: :::...: ... .. :.: . : :
XP_006 NRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSS-L
210 220 230 240 250 260
590 600 610 620 630 640
pF1KB8 ICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESG
: .:::::::: :... .: ::.. . : :..:: :. . . ::
XP_006 SSITSLKKLCNHPALIYD-----KCV------EEEDGFVGALDLFPPGYSSKALEPQLSG
270 280 290 300 310
650 660 670 680 690 700
pF1KB8 KLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQI
:. ::. .::: . : ..::::::::::::......:. . : :.:::: :..: ..
XP_006 KMLVLDYILAVTRS-RSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKV
320 330 340 350 360 370
710 720 730 740 750 760
pF1KB8 VDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYP
:. ::: : :.:.::::::: ::::::...:...: :::::.: :::.::::::::
XP_006 VERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKT
380 390 400 410 420 430
770 780 790 800 810 820
pF1KB8 VHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCV
.:::::..:::::::.::: :..: . ::: . :. .::. :::.:: : :.:
XP_006 CYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVER-HFSLGELKELFILDEASLSD
440 450 460 470 480 490
830 840 850 860 870 880
pF1KB8 THDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHL
::: : :. . . :: :. : . :. :.: :.: . :.
XP_006 THDRLHCR-------------RCVNSR--QIRPPPDGSDCT-----SDLAGWNHCT-DKW
500 510 520 530
890 900 910
pF1KB8 NLTDPFLERI----TENVSFIFQNITTQATGT
.: : :. . ..:.:.
XP_006 GLRDEVLQAAWDAASTAITFVFHQRSHEEQRGLR
540 550 560
>>NP_001192191 (OMIM: 604289,605027) DNA repair and reco (117 aa)
initn: 697 init1: 697 opt: 697 Z-score: 849.4 bits: 165.5 E(85289): 1.4e-40
Smith-Waterman score: 697; 98.1% identity (100.0% similar) in 104 aa overlap (1-104:1-104)
10 20 30 40 50 60
pF1KB8 MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSD
::::::::::::::::::::::::::::::::::::::::::..
NP_001 RICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVQTWMRRHRLVPVHYR
70 80 90 100 110
130 140 150 160 170 180
pF1KB8 SLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEE
>>XP_011540601 (OMIM: 114480,603615,605027) PREDICTED: D (489 aa)
initn: 1231 init1: 554 opt: 699 Z-score: 842.9 bits: 166.3 E(85289): 3.3e-40
Smith-Waterman score: 1245; 43.8% identity (68.3% similar) in 502 aa overlap (405-901:12-478)
380 390 400 410 420 430
pF1KB8 QKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGH
.:::::: . . ... . :.::::::
XP_011 MNQRGARVSSPILIISYETFRLHVGVLQKGSVGLVICDEGH
10 20 30 40
440 450 460 470 480 490
pF1KB8 RLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEE
::::: .: :: ::. .:....:::::::: :.:.:. ::: ::::. ..: .:
XP_011 RLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFEL
50 60 70 80 90 100
500 510 520 530 540 550
pF1KB8 PIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGAL
::. .:. .::: ...:::.: ::: ... ..:::..:..:::: :::.:: :: :
XP_011 PILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPL
110 120 130 140 150 160
560 570 580 590 600 610
pF1KB8 QIELYRKLL-NSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDK
: :::...: ... .. :.: . : : : .:::::::: :... .:
XP_011 QTELYKRFLRQAKPAEELLEGKMSVSS-LSSITSLKKLCNHPALIYD-----KCV-----
170 180 190 200 210
620 630 640 650 660 670
pF1KB8 NEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTL
::.. . : :..:: :. . . :::. ::. .::: . : ..::::::::::::
XP_011 -EEEDGFVGALDLFPPGYSSKALEPQLSGKMLVLDYILAVTRS-RSSDKVVLVSNYTQTL
220 230 240 250 260
680 690 700 710 720 730
pF1KB8 NILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGS
......:. . : :.:::: :..: ..:. ::: : :.:.::::::: ::::::..
XP_011 DLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGAN
270 280 290 300 310 320
740 750 760 770 780 790
pF1KB8 HLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVV
.:...: :::::.: :::.:::::::: .:::::..:::::::.::: :..: . ::
XP_011 RLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVV
330 340 350 360 370 380
800 810 820 830 840 850
pF1KB8 DLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQL
: . :. .::. :::.:: : :.: ::: : :. . . :: :.
XP_011 DEEQDVER-HFSLGELKELFILDEASLSDTHDRLHCR-------------RCVNSR--QI
390 400 410 420 430
860 870 880 890 900
pF1KB8 GPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERI----TENVSFIFQNITTQATG
: . :. :.: :.: . :. .: : :. . ..:.:.
XP_011 RPPPDGSDCT-----SDLAGWNHCT-DKWGLRDEVLQAAWDAASTAITFVFHQRSHEEQR
440 450 460 470 480
910
pF1KB8 T
XP_011 GLR
>>XP_011540602 (OMIM: 114480,603615,605027) PREDICTED: D (489 aa)
initn: 1231 init1: 554 opt: 699 Z-score: 842.9 bits: 166.3 E(85289): 3.3e-40
Smith-Waterman score: 1245; 43.8% identity (68.3% similar) in 502 aa overlap (405-901:12-478)
380 390 400 410 420 430
pF1KB8 QKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGH
.:::::: . . ... . :.::::::
XP_011 MNQRGARVSSPILIISYETFRLHVGVLQKGSVGLVICDEGH
10 20 30 40
440 450 460 470 480 490
pF1KB8 RLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEE
::::: .: :: ::. .:....:::::::: :.:.:. ::: ::::. ..: .:
XP_011 RLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFEL
50 60 70 80 90 100
500 510 520 530 540 550
pF1KB8 PIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGAL
::. .:. .::: ...:::.: ::: ... ..:::..:..:::: :::.:: :: :
XP_011 PILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPL
110 120 130 140 150 160
560 570 580 590 600 610
pF1KB8 QIELYRKLL-NSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDK
: :::...: ... .. :.: . : : : .:::::::: :... .:
XP_011 QTELYKRFLRQAKPAEELLEGKMSVSS-LSSITSLKKLCNHPALIYD-----KCV-----
170 180 190 200 210
620 630 640 650 660 670
pF1KB8 NEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTL
::.. . : :..:: :. . . :::. ::. .::: . : ..::::::::::::
XP_011 -EEEDGFVGALDLFPPGYSSKALEPQLSGKMLVLDYILAVTRS-RSSDKVVLVSNYTQTL
220 230 240 250 260
680 690 700 710 720 730
pF1KB8 NILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGS
......:. . : :.:::: :..: ..:. ::: : :.:.::::::: ::::::..
XP_011 DLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGAN
270 280 290 300 310 320
740 750 760 770 780 790
pF1KB8 HLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVV
.:...: :::::.: :::.:::::::: .:::::..:::::::.::: :..: . ::
XP_011 RLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVV
330 340 350 360 370 380
800 810 820 830 840 850
pF1KB8 DLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQL
: . :. .::. :::.:: : :.: ::: : :. . . :: :.
XP_011 DEEQDVER-HFSLGELKELFILDEASLSDTHDRLHCR-------------RCVNSR--QI
390 400 410 420 430
860 870 880 890 900
pF1KB8 GPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERI----TENVSFIFQNITTQATG
: . :. :.: :.: . :. .: : :. . ..:.:.
XP_011 RPPPDGSDCT-----SDLAGWNHCT-DKWGLRDEVLQAAWDAASTAITFVFHQRSHEEQR
440 450 460 470 480
910
pF1KB8 T
XP_011 GLR
>>NP_000115 (OMIM: 133540,211980,214150,278800,600630,60 (1493 aa)
initn: 755 init1: 316 opt: 485 Z-score: 576.6 bits: 118.6 E(85289): 2.2e-25
Smith-Waterman score: 944; 34.6% identity (62.1% similar) in 541 aa overlap (288-815:499-1007)
260 270 280 290 300 310
pF1KB8 YTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYE--CVMGMR
. .: .: .:. :. .:.: :
NP_000 NKLRLQDKEKRLKLEDDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHC-----
470 480 490 500 510 520
320 330 340 350 360 370
pF1KB8 MNGRCGAILADEMGLGKTLQCISLIWTL-----QCQGPYGGKPVIKKTLIVTPGSLVNNW
. :.::.::::::::.: :... : . .: . :.:: : .....:
NP_000 --QQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQW
530 540 550 560 570 580
380 390 400 410 420
pF1KB8 KKEFQKWLGSERIKIF--TVDQDHKVEEFIKSI--FYSVLIISYEMLLRSLDQIKNIKFD
:::. : :. :. : . :: :..:... ...:: :: .. :.:. .
NP_000 VKEFHTWWPPFRVAILHETGSYTHKKEKLIRDVAHCHGILITSYSYIRLMQDDISRYDWH
590 600 610 620 630 640
430 440 450 460 470 480
pF1KB8 LLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLS
.: ::::...: .: : .. .::::.:.:.::.:.:...:.::. :: ::.:
NP_000 YVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLP
650 660 670 680 690 700
490 500 510 520 530 540
pF1KB8 SYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYL--PPKIE
. . . :: .. .:: . . . . : : . ..::: . .. : : : :
NP_000 VFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNE
710 720 730 740 750 760
550 560 570 580 590 600
pF1KB8 NVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKE
.:.::: : ..:.....:. : :.: .. :: ::.:.:::: :. :
NP_000 QVLFCRLTDEQHKVYQNFVDSKEVYRILNGEMQIFSGLI---ALRKICNHPDLF--SGGP
770 780 790 800 810
610 620 630 640 650 660
pF1KB8 KECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVV
:. .. : . :.. . : :.:::. :. .:: . : . ..:.
NP_000 KNLKGLPDDELEEDQF-GYW--------------KRSGKMIVVESLLKIWH--KQGQRVL
820 830 840 850
670 680 690 700 710 720
pF1KB8 LVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGG
: :. : :.::. . . :.: ..:: : :..:: .. .: . .:.:.:::....::
NP_000 LFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYN-EDTSIFVFLLTTRVGG
860 870 880 890 900 910
730 740 750 760 770 780
pF1KB8 VGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQIS
.:.:: :......:: ::::.:: :: :.:: ::: : .:::::.::::::::.:::
NP_000 LGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIF
920 930 940 950 960 970
790 800 810 820 830 840
pF1KB8 KQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEK
:: : . :. : . :. ..: .::::
NP_000 KQFLTNRVLKDPKQRRF--FKSNDLYELFTLTSPDASQSTETSAIFAGTGSDVQTPKCHL
980 990 1000 1010 1020 1030
850 860 870 880 890 900
pF1KB8 FIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNIT
NP_000 KRRIQPAFGADHDVPKRKKFPASNISVNDATSSEEKSEAKGAEVNAVTSNRSDPLKDDPH
1040 1050 1060 1070 1080 1090
>>NP_001333369 (OMIM: 133540,211980,214150,278800,600630 (1493 aa)
initn: 755 init1: 316 opt: 485 Z-score: 576.6 bits: 118.6 E(85289): 2.2e-25
Smith-Waterman score: 944; 34.6% identity (62.1% similar) in 541 aa overlap (288-815:499-1007)
260 270 280 290 300 310
pF1KB8 YTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYE--CVMGMR
. .: .: .:. :. .:.: :
NP_001 NKLRLQDKEKRLKLEDDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHC-----
470 480 490 500 510 520
320 330 340 350 360 370
pF1KB8 MNGRCGAILADEMGLGKTLQCISLIWTL-----QCQGPYGGKPVIKKTLIVTPGSLVNNW
. :.::.::::::::.: :... : . .: . :.:: : .....:
NP_001 --QQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQW
530 540 550 560 570 580
380 390 400 410 420
pF1KB8 KKEFQKWLGSERIKIF--TVDQDHKVEEFIKSI--FYSVLIISYEMLLRSLDQIKNIKFD
:::. : :. :. : . :: :..:... ...:: :: .. :.:. .
NP_001 VKEFHTWWPPFRVAILHETGSYTHKKEKLIRDVAHCHGILITSYSYIRLMQDDISRYDWH
590 600 610 620 630 640
430 440 450 460 470 480
pF1KB8 LLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLS
.: ::::...: .: : .. .::::.:.:.::.:.:...:.::. :: ::.:
NP_001 YVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLP
650 660 670 680 690 700
490 500 510 520 530 540
pF1KB8 SYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYL--PPKIE
. . . :: .. .:: . . . . : : . ..::: . .. : : : :
NP_001 VFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNE
710 720 730 740 750 760
550 560 570 580 590 600
pF1KB8 NVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKE
.:.::: : ..:.....:. : :.: .. :: ::.:.:::: :. :
NP_001 QVLFCRLTDEQHKVYQNFVDSKEVYRILNGEMQIFSGLI---ALRKICNHPDLF--SGGP
770 780 790 800 810
610 620 630 640 650 660
pF1KB8 KECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVV
:. .. : . :.. . : :.:::. :. .:: . : . ..:.
NP_001 KNLKGLPDDELEEDQF-GYW--------------KRSGKMIVVESLLKIWH--KQGQRVL
820 830 840 850
670 680 690 700 710 720
pF1KB8 LVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGG
: :. : :.::. . . :.: ..:: : :..:: .. .: . .:.:.:::....::
NP_001 LFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYN-EDTSIFVFLLTTRVGG
860 870 880 890 900 910
730 740 750 760 770 780
pF1KB8 VGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQIS
.:.:: :......:: ::::.:: :: :.:: ::: : .:::::.::::::::.:::
NP_001 LGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIF
920 930 940 950 960 970
790 800 810 820 830 840
pF1KB8 KQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEK
:: : . :. : . :. ..: .::::
NP_001 KQFLTNRVLKDPKQRRF--FKSNDLYELFTLTSPDASQSTETSAIFAGTGSDVQTPKCHL
980 990 1000 1010 1020 1030
850 860 870 880 890 900
pF1KB8 FIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNIT
NP_001 KRRIQPAFGADHDVPKRKKFPASNISVNDATSSEEKSEAKGAEVNAVTSNRSDPLKDDPH
1040 1050 1060 1070 1080 1090
910 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:43:16 2016 done: Sat Nov 5 16:43:18 2016
Total Scan time: 13.290 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]