Result of FASTA (omim) for
pFN21AB5874
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5874, 494 aa
1>>>pF1KB5874 494 - 494 aa - 494 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.5901+/-0.000667; mu= -13.3072+/- 0.042
mean_var=554.0721+/-112.585, 0's: 0 Z-trim(118.6): 403 B-trim: 1939 in 2/56
Lambda= 0.054487
statistics sampled from 31189 (31632) to 31189 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.371), width: 16
Scan time: 10.730
The best scores are: opt bits E(85289)
NP_005617 (OMIM: 601940) serine/arginine-rich spli ( 494) 3163 263.7 8.6e-70
XP_011540253 (OMIM: 601940) PREDICTED: serine/argi ( 464) 1728 150.9 7.5e-36
NP_006266 (OMIM: 601944) serine/arginine-rich spli ( 344) 1385 123.8 8e-28
XP_005268056 (OMIM: 600914) PREDICTED: serine/argi ( 271) 1027 95.5 2e-19
XP_005268057 (OMIM: 600914) PREDICTED: serine/argi ( 271) 1027 95.5 2e-19
XP_016877082 (OMIM: 600914) PREDICTED: serine/argi ( 271) 1027 95.5 2e-19
NP_008856 (OMIM: 600914) serine/arginine-rich spli ( 272) 1020 95.0 2.9e-19
NP_001307143 (OMIM: 600914) serine/arginine-rich s ( 272) 1020 95.0 2.9e-19
NP_001034554 (OMIM: 600914) serine/arginine-rich s ( 272) 1020 95.0 2.9e-19
XP_011535379 (OMIM: 600914) PREDICTED: serine/argi ( 239) 646 65.5 1.9e-10
NP_008855 (OMIM: 600812) serine/arginine-rich spli ( 248) 599 61.8 2.5e-09
XP_016877083 (OMIM: 600914) PREDICTED: serine/argi ( 145) 493 53.3 5.6e-07
NP_001071634 (OMIM: 600812) serine/arginine-rich s ( 201) 464 51.1 3.4e-06
XP_016864545 (OMIM: 609268) PREDICTED: splicing re ( 359) 438 49.4 2.1e-05
NP_001310463 (OMIM: 609268) splicing regulatory gl ( 359) 438 49.4 2.1e-05
NP_001310464 (OMIM: 609268) splicing regulatory gl ( 358) 436 49.2 2.3e-05
XP_011541473 (OMIM: 609268) PREDICTED: splicing re ( 508) 438 49.5 2.7e-05
NP_001310456 (OMIM: 609268) splicing regulatory gl ( 508) 438 49.5 2.7e-05
NP_631907 (OMIM: 609268) splicing regulatory gluta ( 508) 438 49.5 2.7e-05
XP_005247024 (OMIM: 606093) PREDICTED: peptidyl-pr ( 754) 441 49.9 3e-05
NP_004783 (OMIM: 606093) peptidyl-prolyl cis-trans ( 754) 441 49.9 3e-05
XP_005247023 (OMIM: 606093) PREDICTED: peptidyl-pr ( 754) 441 49.9 3e-05
NP_001257421 (OMIM: 609268) splicing regulatory gl ( 507) 436 49.4 3e-05
NP_001070667 (OMIM: 609268) splicing regulatory gl ( 624) 438 49.6 3.1e-05
XP_005255283 (OMIM: 606032) PREDICTED: serine/argi (2751) 455 51.6 3.4e-05
NP_057417 (OMIM: 606032) serine/arginine repetitiv (2752) 455 51.6 3.4e-05
NP_001310458 (OMIM: 609268) splicing regulatory gl ( 623) 436 49.4 3.4e-05
NP_003760 (OMIM: 601943) serine/arginine-rich spli ( 221) 414 47.2 5.6e-05
XP_016872631 (OMIM: 603269) PREDICTED: serine/argi ( 282) 394 45.8 0.0002
NP_115285 (OMIM: 603269) serine/arginine-rich spli ( 282) 394 45.8 0.0002
NP_001310462 (OMIM: 609268) splicing regulatory gl ( 538) 396 46.2 0.00027
XP_016879869 (OMIM: 614396) PREDICTED: G patch dom (1288) 389 46.1 0.00073
NP_001291869 (OMIM: 614396) G patch domain-contain (1424) 389 46.1 0.00078
NP_001291871 (OMIM: 614396) G patch domain-contain (1424) 389 46.1 0.00078
XP_016879867 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078
XP_016879866 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078
XP_016879865 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078
NP_001291872 (OMIM: 614396) G patch domain-contain (1424) 389 46.1 0.00078
XP_016879864 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078
XP_016879868 (OMIM: 614396) PREDICTED: G patch dom (1424) 389 46.1 0.00078
NP_001291870 (OMIM: 614396) G patch domain-contain (1424) 389 46.1 0.00078
XP_016858323 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079
XP_016858319 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079
XP_016858320 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079
XP_016858321 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079
XP_016858322 (OMIM: 602010) PREDICTED: serine/argi ( 293) 369 43.8 0.00079
XP_011522860 (OMIM: 614396) PREDICTED: G patch dom (1453) 389 46.1 0.00079
XP_016879862 (OMIM: 614396) PREDICTED: G patch dom (1453) 389 46.1 0.00079
XP_016879861 (OMIM: 614396) PREDICTED: G patch dom (1453) 389 46.1 0.00079
XP_011522861 (OMIM: 614396) PREDICTED: G patch dom (1453) 389 46.1 0.00079
>>NP_005617 (OMIM: 601940) serine/arginine-rich splicing (494 aa)
initn: 3163 init1: 3163 opt: 3163 Z-score: 1374.0 bits: 263.7 E(85289): 8.6e-70
Smith-Waterman score: 3163; 99.8% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RSKKEKSRSPSKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS
430 440 450 460 470 480
490
pF1KB5 RSPSRSRSRSHSRS
::::::::::::::
NP_005 RSPSRSRSRSHSRS
490
>>XP_011540253 (OMIM: 601940) PREDICTED: serine/arginine (464 aa)
initn: 2125 init1: 1719 opt: 1728 Z-score: 764.7 bits: 150.9 E(85289): 7.5e-36
Smith-Waterman score: 2909; 93.7% identity (93.9% similar) in 494 aa overlap (1-494:1-464)
10 20 30 40 50 60
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS
:::::::::::::: ::::::::::::::::
XP_011 RRRSYSRSRSHSRS------------------------------GSRSRSKSRSRSQSRS
190 200 210
250 260 270 280 290 300
pF1KB5 RSKKEKSRSPSKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS
400 410 420 430 440 450
490
pF1KB5 RSPSRSRSRSHSRS
::::::::::::::
XP_011 RSPSRSRSRSHSRS
460
>>NP_006266 (OMIM: 601944) serine/arginine-rich splicing (344 aa)
initn: 841 init1: 841 opt: 1385 Z-score: 620.5 bits: 123.8 E(85289): 8e-28
Smith-Waterman score: 1427; 66.5% identity (80.9% similar) in 361 aa overlap (1-352:1-344)
10 20 30 40 50 60
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL
:::::::::::..::.:..:::.:::..::::::::::::::.: :::::::::::::.:
NP_006 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 CGERVIVEHARGPRRD--G-SYGSGRSGYGY---RRSGRDKYGPPTRTEYRLIVENLSSR
:::::::::::::::: : :::: .: :: : :::::::::.::::::::::::::
NP_006 CGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 CSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE
::::::::.:::::::::::::: : ::::::: :::::::::.::::::.:::.:::.:
NP_006 CSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS
::: . .::::: :::.:::: ::: :::: .: .::::: : :::::.:::
NP_006 DKPRTSHRRSYSGSRSRSRSRRRSR----SRSRRSS------RSRSRSISKSRSRSRSRS
190 200 210 220 230
240 250 260 270 280 290
pF1KB5 RSQSRSRSKKEKSRSPSKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH
...:::::: .:::: ::.: .: : ..:::.:::. :. . .. .::::...
NP_006 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEK------SRSRSRSRSPKEN
240 250 260 270 280
300 310 320 330 340 350
pF1KB5 KS---KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK
. ::::::::: : :..:: ... :::::.. :.:::::::.:.
NP_006 GKGDIKSKSRSRSQSRSNSPLPVPP-SKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSV
:
NP_006 D
>>XP_005268056 (OMIM: 600914) PREDICTED: serine/arginine (271 aa)
initn: 1188 init1: 480 opt: 1027 Z-score: 469.7 bits: 95.5 E(85289): 2e-19
Smith-Waterman score: 1027; 61.7% identity (81.6% similar) in 277 aa overlap (3-271:5-268)
10 20 30 40 50
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK
::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.::
XP_005 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC
.::.::: .::::. : :. : :: . .. :: :. . ::.::: ::::::::::
XP_005 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED
:::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.:
XP_005 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR
::.:.:: :::::..:: :::: ::::: :..:.:.::::::: :::.:.: ::
XP_005 --GSKRHRSRSRSRSRTRSSSRSR----SRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS
: .:..:... .:.:: : :..:::: .:::.: :
XP_005 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN
240 250 260 270
300 310 320 330 340 350
pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS
>>XP_005268057 (OMIM: 600914) PREDICTED: serine/arginine (271 aa)
initn: 1188 init1: 480 opt: 1027 Z-score: 469.7 bits: 95.5 E(85289): 2e-19
Smith-Waterman score: 1027; 61.7% identity (81.6% similar) in 277 aa overlap (3-271:5-268)
10 20 30 40 50
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK
::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.::
XP_005 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC
.::.::: .::::. : :. : :: . .. :: :. . ::.::: ::::::::::
XP_005 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED
:::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.:
XP_005 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR
::.:.:: :::::..:: :::: ::::: :..:.:.::::::: :::.:.: ::
XP_005 --GSKRHRSRSRSRSRTRSSSRSR----SRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS
: .:..:... .:.:: : :..:::: .:::.: :
XP_005 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN
240 250 260 270
300 310 320 330 340 350
pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS
>>XP_016877082 (OMIM: 600914) PREDICTED: serine/arginine (271 aa)
initn: 1188 init1: 480 opt: 1027 Z-score: 469.7 bits: 95.5 E(85289): 2e-19
Smith-Waterman score: 1027; 61.7% identity (81.6% similar) in 277 aa overlap (3-271:5-268)
10 20 30 40 50
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK
::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.::
XP_016 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC
.::.::: .::::. : :. : :: . .. :: :. . ::.::: ::::::::::
XP_016 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED
:::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.:
XP_016 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR
::.:.:: :::::..:: :::: ::::: :..:.:.::::::: :::.:.: ::
XP_016 --GSKRHRSRSRSRSRTRSSSRSR----SRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS
: .:..:... .:.:: : :..:::: .:::.: :
XP_016 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN
240 250 260 270
300 310 320 330 340 350
pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS
>>NP_008856 (OMIM: 600914) serine/arginine-rich splicing (272 aa)
initn: 1381 init1: 525 opt: 1020 Z-score: 466.7 bits: 95.0 E(85289): 2.9e-19
Smith-Waterman score: 1020; 61.0% identity (81.2% similar) in 277 aa overlap (3-271:5-269)
10 20 30 40 50
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK
::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.::
NP_008 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC
.::.::: .::::. : :. : :: . .. :: :. . ::.::: ::::::::::
NP_008 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED
:::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.:
NP_008 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR
::.: .:::::.::::.:: .::::: :..:.:.::::::: :::.:.: ::
NP_008 --GSKR---HSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS
: .:..:... .:.:: : :..:::: .:::.: :
NP_008 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN
240 250 260 270
300 310 320 330 340 350
pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS
>>NP_001307143 (OMIM: 600914) serine/arginine-rich splic (272 aa)
initn: 1381 init1: 525 opt: 1020 Z-score: 466.7 bits: 95.0 E(85289): 2.9e-19
Smith-Waterman score: 1020; 61.0% identity (81.2% similar) in 277 aa overlap (3-271:5-269)
10 20 30 40 50
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK
::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.::
NP_001 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC
.::.::: .::::. : :. : :: . .. :: :. . ::.::: ::::::::::
NP_001 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED
:::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.:
NP_001 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR
::.: .:::::.::::.:: .::::: :..:.:.::::::: :::.:.: ::
NP_001 --GSKR---HSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS
: .:..:... .:.:: : :..:::: .:::.: :
NP_001 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN
240 250 260 270
300 310 320 330 340 350
pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS
>>NP_001034554 (OMIM: 600914) serine/arginine-rich splic (272 aa)
initn: 1381 init1: 525 opt: 1020 Z-score: 466.7 bits: 95.0 E(85289): 2.9e-19
Smith-Waterman score: 1020; 61.0% identity (81.2% similar) in 277 aa overlap (3-271:5-269)
10 20 30 40 50
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK
::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.::
NP_001 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSG--YGYRRSGRDKYG-PPTRTEYRLIVENLSSRC
.::.::: .::::. : :. : :: . .. :: :. . ::.::: ::::::::::
NP_001 ELCSERVTIEHARA-RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVED
:::::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.:
NP_001 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR
::.: .:::::.::::.:: .::::: :..:.:.::::::: :::.:.: ::
NP_001 --GSKR---HSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 S----QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS
: .:..:... .:.:: : :..:::: .:::.: :
NP_001 SPVPEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN
240 250 260 270
300 310 320 330 340 350
pF1KB5 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS
>>XP_011535379 (OMIM: 600914) PREDICTED: serine/arginine (239 aa)
initn: 676 init1: 525 opt: 646 Z-score: 308.5 bits: 65.5 E(85289): 1.9e-10
Smith-Waterman score: 896; 56.9% identity (74.8% similar) in 274 aa overlap (3-271:5-236)
10 20 30 40 50
pF1KB5 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGK
::.::::. :::.::::::::::.: ..::: :.:::::.: ::::::::::.::
XP_011 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 DLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQ
.::.:: .::.::: :::::::::: :::
XP_011 ELCSER-------------------------------NAPPVRTENRLIVENLSSRVSWQ
70 80
120 130 140 150 160 170
pF1KB5 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPG
::::.::::::::.::::. . ::::.::.::.:.: :.:::.: :.:::::.:.: :
XP_011 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE---G
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB5 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS--
:.: .:::::.::::.:: .::::: :..:.:.::::::: :::.:.: :::
XP_011 SKR---HSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSRSVSRSPV
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB5 --QSRSRSKKEKSRSP-SKDKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR
.:..:... .:.:: : :..:::: .:::.: :
XP_011 PEKSQKRGSSSRSKSPASVDRQRSRS----RSRSRSVDSGN
210 220 230
300 310 320 330 340 350
pF1KB5 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK
494 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:25:46 2016 done: Sat Nov 5 15:25:48 2016
Total Scan time: 10.730 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]