Result of FASTA (omim) for
pFN21AB5869
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5869, 463 aa
1>>>pF1KB5869 463 - 463 aa - 463 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7620+/-0.000369; mu= 2.4984+/- 0.023
mean_var=188.7011+/-38.802, 0's: 0 Z-trim(119.1): 402 B-trim: 421 in 1/57
Lambda= 0.093366
statistics sampled from 32358 (32773) to 32358 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.384), width: 16
Scan time: 10.380
The best scores are: opt bits E(85289)
NP_008848 (OMIM: 180247) retinoic acid receptor RX ( 463) 3107 430.8 3.7e-120
NP_001243499 (OMIM: 180247) retinoic acid receptor ( 340) 2280 319.4 9.7e-87
NP_001243500 (OMIM: 180247) retinoic acid receptor ( 340) 2280 319.4 9.7e-87
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 2162 303.6 7.6e-82
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 2151 302.1 2e-81
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 2044 287.6 3.8e-77
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 1942 274.0 7.1e-73
NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 1785 252.8 1.7e-66
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 1761 249.5 1.3e-65
XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 1745 247.4 5.9e-65
XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 1736 246.2 1.3e-64
NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 1721 244.1 4.6e-64
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 976 143.8 8.6e-34
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423) 976 143.8 8.7e-34
NP_001245284 (OMIM: 125850,125853,600281,616026) h ( 467) 906 134.4 6.5e-31
XP_005260464 (OMIM: 125850,125853,600281,616026) P ( 513) 906 134.4 7e-31
NP_849181 (OMIM: 125850,125853,600281,616026) hepa ( 417) 903 133.9 7.8e-31
NP_849180 (OMIM: 125850,125853,600281,616026) hepa ( 464) 903 134.0 8.6e-31
NP_000448 (OMIM: 125850,125853,600281,616026) hepa ( 474) 903 134.0 8.7e-31
NP_004124 (OMIM: 605966) hepatocyte nuclear factor ( 445) 902 133.8 9.1e-31
NP_001274113 (OMIM: 125850,125853,600281,616026) h ( 392) 898 133.3 1.2e-30
NP_001025175 (OMIM: 125850,125853,600281,616026) h ( 395) 898 133.3 1.2e-30
NP_001274111 (OMIM: 125850,125853,600281,616026) h ( 439) 898 133.3 1.3e-30
NP_001025174 (OMIM: 125850,125853,600281,616026) h ( 442) 898 133.3 1.3e-30
NP_001274112 (OMIM: 125850,125853,600281,616026) h ( 449) 898 133.3 1.3e-30
NP_787110 (OMIM: 125850,125853,600281,616026) hepa ( 452) 898 133.3 1.3e-30
NP_001317490 (OMIM: 605966) hepatocyte nuclear fac ( 408) 897 133.1 1.3e-30
XP_016868864 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 897 133.1 1.3e-30
XP_016868863 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 897 133.1 1.3e-30
XP_016868865 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 897 133.1 1.3e-30
XP_016868862 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 897 133.1 1.3e-30
XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP ( 273) 574 89.5 1.2e-17
NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261) 571 89.1 1.5e-17
NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261) 571 89.1 1.5e-17
NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281) 571 89.1 1.6e-17
XP_006719427 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 524 83.0 2.5e-15
XP_006719426 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 524 83.0 2.5e-15
XP_005268881 (OMIM: 139139) PREDICTED: nuclear rec ( 598) 524 83.0 2.5e-15
NP_002126 (OMIM: 139139) nuclear receptor subfamil ( 598) 524 83.0 2.5e-15
NP_775180 (OMIM: 139139) nuclear receptor subfamil ( 598) 524 83.0 2.5e-15
XP_016874736 (OMIM: 139139) PREDICTED: nuclear rec ( 602) 524 83.0 2.5e-15
NP_001189162 (OMIM: 139139) nuclear receptor subfa ( 611) 524 83.0 2.5e-15
NP_001189163 (OMIM: 139139) nuclear receptor subfa ( 652) 524 83.0 2.6e-15
XP_005268879 (OMIM: 139139) PREDICTED: nuclear rec ( 670) 524 83.0 2.7e-15
XP_011532365 (OMIM: 601426) PREDICTED: nuclear rec ( 629) 496 79.2 3.5e-14
XP_016862609 (OMIM: 601426) PREDICTED: nuclear rec ( 596) 486 77.9 8.5e-14
NP_001278623 (OMIM: 601426) nuclear receptor subfa ( 596) 486 77.9 8.5e-14
NP_003289 (OMIM: 601426) nuclear receptor subfamil ( 615) 486 77.9 8.7e-14
XP_011532368 (OMIM: 601426) PREDICTED: nuclear rec ( 615) 486 77.9 8.7e-14
XP_011532367 (OMIM: 601426) PREDICTED: nuclear rec ( 615) 486 77.9 8.7e-14
>>NP_008848 (OMIM: 180247) retinoic acid receptor RXR-ga (463 aa)
initn: 3107 init1: 3107 opt: 3107 Z-score: 2278.3 bits: 430.8 E(85289): 3.7e-120
Smith-Waterman score: 3107; 100.0% identity (100.0% similar) in 463 aa overlap (1-463:1-463)
10 20 30 40 50 60
pF1KB5 MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 EAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
370 380 390 400 410 420
430 440 450 460
pF1KB5 LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
:::::::::::::::::::::::::::::::::::::::::::
NP_008 LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
430 440 450 460
>>NP_001243499 (OMIM: 180247) retinoic acid receptor RXR (340 aa)
initn: 2280 init1: 2280 opt: 2280 Z-score: 1678.2 bits: 319.4 E(85289): 9.7e-87
Smith-Waterman score: 2280; 100.0% identity (100.0% similar) in 340 aa overlap (124-463:1-340)
100 110 120 130 140 150
pF1KB5 APPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGV
::::::::::::::::::::::::::::::
NP_001 MNYPSTSPGSLVKHICAICGDRSSGKHYGV
10 20 30
160 170 180 190 200 210
pF1KB5 YSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEER
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB5 QRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAA
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB5 DKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHV
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 HRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETL
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 REKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLM
280 290 300 310 320 330
460
pF1KB5 EMLETPLQIT
::::::::::
NP_001 EMLETPLQIT
340
>>NP_001243500 (OMIM: 180247) retinoic acid receptor RXR (340 aa)
initn: 2280 init1: 2280 opt: 2280 Z-score: 1678.2 bits: 319.4 E(85289): 9.7e-87
Smith-Waterman score: 2280; 100.0% identity (100.0% similar) in 340 aa overlap (124-463:1-340)
100 110 120 130 140 150
pF1KB5 APPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGV
::::::::::::::::::::::::::::::
NP_001 MNYPSTSPGSLVKHICAICGDRSSGKHYGV
10 20 30
160 170 180 190 200 210
pF1KB5 YSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEER
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB5 QRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAA
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB5 DKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHV
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 HRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETL
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 REKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLM
280 290 300 310 320 330
460
pF1KB5 EMLETPLQIT
::::::::::
NP_001 EMLETPLQIT
340
>>NP_002948 (OMIM: 180245) retinoic acid receptor RXR-al (462 aa)
initn: 2139 init1: 1217 opt: 2162 Z-score: 1590.4 bits: 303.6 E(85289): 7.6e-82
Smith-Waterman score: 2162; 74.1% identity (87.2% similar) in 452 aa overlap (18-463:21-462)
10 20 30 40 50
pF1KB5 MYGNYSHFMKFPAGYGGSPGHTGSTSMS-PSAALSTGKPMDSHPSYTDTPVSAPRTL
:: :: ::. :: : : . : :. .:.: ::
NP_002 MDTKHFLPLDFSTQVNSSLTSP--TGRGSMAAPSLHPSLGPGIGS-PGQLHSPIS---TL
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 SAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNV-VNSVSSSEDIKPL
: .:.:..: :. ::.: ::: : .. . : ... . : ::. .: :::::::::
NP_002 S---SPINGMGPPFSVISSPMGPHSMSVPTTPTLGF-STGSPQLSSPMNPVSSSEDIKPP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PGLPGIGNM-NYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYT
:: :. .. .:: . .:..:::::::::::::::::::::::::::::::.:::: ::
NP_002 LGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 CRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDM
::::::::::::::::::::::::::.::::::::::::::...: :.:.: ..:..:::
NP_002 CRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 PVERILEAELAVEPKTESYGDMNM---ENSTNDPVTNICHAADKQLFTLVEWAKRIPHFS
:::::::::::::::::.: . :: .: ::::::::.::::::::::::::::::::
NP_002 PVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 DLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVL
.: :.::::::::::::::::::::::..:.:::::::::::::.::::::::.::::::
NP_002 ELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 TELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPE
:::::::.::::::.::::::::::::::.::::::.:::.:::::::.:::: :.::::
NP_002 TELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPE
360 370 380 390 400 410
420 430 440 450 460
pF1KB5 QPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
::::::::::::::::::::::::::::::::::::::::::::::.: :.:
NP_002 QPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
420 430 440 450 460
>>NP_001278849 (OMIM: 180245) retinoic acid receptor RXR (435 aa)
initn: 2139 init1: 1217 opt: 2151 Z-score: 1582.7 bits: 302.1 E(85289): 2e-81
Smith-Waterman score: 2151; 74.6% identity (88.0% similar) in 441 aa overlap (28-463:3-435)
10 20 30 40 50 60
pF1KB5 MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG
.:: : : . : :. .:.: :::
NP_001 MAAPSLHPSLGPGIGS-PGQLHSPIS---TLS---
10 20
70 80 90 100 110
pF1KB5 TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNV-VNSVSSSEDIKPLPGLP
.:.:..: :. ::.: ::: : .. . : ... . : ::. .: ::::::::: ::
NP_001 SPINGMGPPFSVISSPMGPHSMSVPTTPTLGF-STGSPQLSSPMNPVSSSEDIKPPLGLN
30 40 50 60 70 80
120 130 140 150 160 170
pF1KB5 GIGNM-NYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDN
:. .. .:: . .:..:::::::::::::::::::::::::::::::.:::: ::::::
NP_001 GVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDN
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB5 KDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVER
::::::::::::::::::::::.::::::::::::::...: :.:.: ..:..:::::::
NP_001 KDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVER
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB5 ILEAELAVEPKTESYGDMNM---ENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTL
:::::::::::::.: . :: .: ::::::::.::::::::::::::::::::.: :
NP_001 ILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPL
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB5 EDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELV
.::::::::::::::::::::::..:.:::::::::::::.::::::::.::::::::::
NP_001 DDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELV
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB5 SKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGR
:::.::::::.::::::::::::::.::::::.:::.:::::::.:::: :.::::::::
NP_001 SKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGR
330 340 350 360 370 380
420 430 440 450 460
pF1KB5 FAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
::::::::::::::::::::::::::::::::::::::::::.: :.:
NP_001 FAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
390 400 410 420 430
>>NP_001278850 (OMIM: 180245) retinoic acid receptor RXR (365 aa)
initn: 2048 init1: 1217 opt: 2044 Z-score: 1506.0 bits: 287.6 E(85289): 3.8e-77
Smith-Waterman score: 2044; 83.0% identity (94.0% similar) in 365 aa overlap (103-463:1-365)
80 90 100 110 120 130
pF1KB5 ITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNM-NYPSTSP
.: ::::::::: :: :. .. .:: .
NP_001 MNPVSSSEDIKPPLGLNGVLKVPAHPSGNM
10 20 30
140 150 160 170 180 190
pF1KB5 GSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRC
.:..:::::::::::::::::::::::::::::::.:::: :::::::::::::::::::
NP_001 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 QYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTE
:::::::::.::::::::::::::...: :.:.: ..:..::::::::::::::::::::
NP_001 QYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTE
100 110 120 130 140 150
260 270 280 290 300
pF1KB5 SYGDMNM---ENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNE
.: . :: .: ::::::::.::::::::::::::::::::.: :.::::::::::::
NP_001 TYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNE
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB5 LLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSEL
::::::::::..:.:::::::::::::.::::::::.:::::::::::::.::::::.::
NP_001 LLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTEL
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB5 GCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRS
::::::::::::.::::::.:::.:::::::.:::: :.:::::::::::::::::::::
NP_001 GCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRS
280 290 300 310 320 330
430 440 450 460
pF1KB5 IGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
:::::::::::::::::::::::::::::.: :.:
NP_001 IGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
340 350 360
>>NP_068811 (OMIM: 180246) retinoic acid receptor RXR-be (533 aa)
initn: 1926 init1: 1199 opt: 1942 Z-score: 1429.3 bits: 274.0 E(85289): 7.1e-73
Smith-Waterman score: 1984; 67.4% identity (81.8% similar) in 473 aa overlap (13-462:68-532)
10 20 30
pF1KB5 MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAA----LSTGKP
:: : : .: : ::... : : :
NP_068 RRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGM-GDSGRDSRSPDSSSPNPLPQGVP
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB5 MDSHPSYTDTPVSAPRTLSAVGTPLNA------LGSPYRVITSAMGPPSGALAAPPGINL
: :. : .:: .:.. :.: ::::. ::.:.:: :. ::::..
NP_068 PPSPPGPPLPPSTAP-SLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFS-
100 110 120 130 140 150
100 110 120 130 140
pF1KB5 VAPPSS-QLNVVNSVSSS-----EDIKPLPGLPGIGNMNYPST--SPGSLVKHICAICGD
.: :: :.: . :. .. ::.:: : : :. ... : .::. :..::::::
NP_068 -GPVSSPQINSTVSLPGGGSGPPEDVKP-PVL-GVRGLHCPPPPGGPGAG-KRLCAICGD
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB5 RSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGM
::::::::::::::::::::::::::: :.::::::: .:::::::::::::::::. ::
NP_068 RSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGM
220 230 240 250 260 270
210 220 230 240 250
pF1KB5 KREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESY-----GDMNME
:::::::::::.... ....: : .. :.:::.:::::::::: :... : .
NP_068 KREAVQEERQRGKDK-DGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSG
280 290 300 310 320
260 270 280 290 300 310
pF1KB5 NSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSV
.: ::::::::.::::::::::::::::::::.: :.::::::::::::::::::::::.
NP_068 SSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSI
330 340 350 360 370 380
320 330 340 350 360 370
pF1KB5 SVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNP
.:.:::::::::::::.::::::::.:::::::::::::.::.:::.::::::::.::::
NP_068 DVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNP
390 400 410 420 430 440
380 390 400 410 420 430
pF1KB5 DAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFF
::::::::::::.:::::::.::.: ::::::: ::::::::::::::::::::::::::
NP_068 DAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFF
450 460 470 480 490 500
440 450 460
pF1KB5 FKLIGDTPIDTFLMEMLETPLQIT
::::::::::::::::::.: :.
NP_068 FKLIGDTPIDTFLMEMLEAPHQLA
510 520 530
>>NP_001257330 (OMIM: 180246) retinoic acid receptor RXR (537 aa)
initn: 1938 init1: 678 opt: 1785 Z-score: 1315.0 bits: 252.8 E(85289): 1.7e-66
Smith-Waterman score: 1966; 66.9% identity (81.1% similar) in 477 aa overlap (13-462:68-536)
10 20 30
pF1KB5 MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAA----LSTGKP
:: : : .: : ::... : : :
NP_001 RRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGM-GDSGRDSRSPDSSSPNPLPQGVP
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB5 MDSHPSYTDTPVSAPRTLSAVGTPLNA------LGSPYRVITSAMGPPSGALAAPPGINL
: :. : .:: .:.. :.: ::::. ::.:.:: :. ::::..
NP_001 PPSPPGPPLPPSTAP-SLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFS-
100 110 120 130 140 150
100 110 120 130 140
pF1KB5 VAPPSS-QLNVVNSVSSS-----EDIKPLPGLPGIGNMNYPST--SPGSLVKHICAICGD
.: :: :.: . :. .. ::.:: : : :. ... : .::. :..::::::
NP_001 -GPVSSPQINSTVSLPGGGSGPPEDVKP-PVL-GVRGLHCPPPPGGPGAG-KRLCAICGD
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB5 RSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGM
::::::::::::::::::::::::::: :.::::::: .:::::::::::::::::. ::
NP_001 RSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGM
220 230 240 250 260 270
210 220 230 240 250
pF1KB5 KREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESY-----GDMNME
:::::::::::.... ....: : .. :.:::.:::::::::: :... : .
NP_001 KREAVQEERQRGKDK-DGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSG
280 290 300 310 320
260 270 280 290 300 310
pF1KB5 NSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSV
.: ::::::::.::::::::::::::::::::.: :.::::::::::::::::::::::.
NP_001 SSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSI
330 340 350 360 370 380
320 330 340 350 360 370
pF1KB5 SVQDGILLATGLHVHRSSAHSAGVGSIFDR----VLTELVSKMKDMQMDKSELGCLRAIV
.:.:::::::::::::.::::::::.:::: :::::::::.::.:::.::::::::.
NP_001 DVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAII
390 400 410 420 430 440
380 390 400 410 420 430
pF1KB5 LFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLE
::::::::::::::::.:::::::.::.: ::::::: ::::::::::::::::::::::
NP_001 LFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLE
450 460 470 480 490 500
440 450 460
pF1KB5 HLFFFKLIGDTPIDTFLMEMLETPLQIT
::::::::::::::::::::::.: :.
NP_001 HLFFFKLIGDTPIDTFLMEMLEAPHQLA
510 520 530
>>XP_016866665 (OMIM: 180246) PREDICTED: retinoic acid r (414 aa)
initn: 1938 init1: 678 opt: 1761 Z-score: 1299.2 bits: 249.5 E(85289): 1.3e-65
Smith-Waterman score: 1922; 72.0% identity (85.9% similar) in 418 aa overlap (62-462:2-413)
40 50 60 70 80 90
pF1KB5 ALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGIN
: ::::. ::.:.:: :. ::::..
XP_016 MPPPPLGSPFPVISSSMGSPGLPPPAPPGFS
10 20 30
100 110 120 130 140
pF1KB5 LVAPPSS-QLNVVNSVSSS-----EDIKPLPGLPGIGNMNYPST--SPGSLVKHICAICG
.: :: :.: . :. .. ::.:: : : :. ... : .::. :..:::::
XP_016 --GPVSSPQINSTVSLPGGGSGPPEDVKP-PVL-GVRGLHCPPPPGGPGAG-KRLCAICG
40 50 60 70 80
150 160 170 180 190 200
pF1KB5 DRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMG
:::::::::::::::::::::::::::: :.::::::: .:::::::::::::::::. :
XP_016 DRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATG
90 100 110 120 130 140
210 220 230 240 250
pF1KB5 MKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESY-----GDMNM
::::::::::::.... ....: : .. :.:::.:::::::::: :... : .
XP_016 MKREAVQEERQRGKDK-DGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGS
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB5 ENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRS
.: ::::::::.::::::::::::::::::::.: :.::::::::::::::::::::::
XP_016 GSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRS
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB5 VSVQDGILLATGLHVHRSSAHSAGVGSIFDR----VLTELVSKMKDMQMDKSELGCLRAI
..:.:::::::::::::.::::::::.:::: :::::::::.::.:::.::::::::
XP_016 IDVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAI
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB5 VLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCL
.::::::::::::::::.:::::::.::.: ::::::: :::::::::::::::::::::
XP_016 ILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCL
330 340 350 360 370 380
440 450 460
pF1KB5 EHLFFFKLIGDTPIDTFLMEMLETPLQIT
:::::::::::::::::::::::.: :.
XP_016 EHLFFFKLIGDTPIDTFLMEMLEAPHQLA
390 400 410
>>XP_005249335 (OMIM: 180246) PREDICTED: retinoic acid r (441 aa)
initn: 1857 init1: 678 opt: 1745 Z-score: 1287.1 bits: 247.4 E(85289): 5.9e-65
Smith-Waterman score: 1837; 76.9% identity (89.6% similar) in 364 aa overlap (110-462:81-440)
80 90 100 110 120 130
pF1KB5 PSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPST--SPGSLVKH
::.:: : : :. ... : .::. :.
XP_005 SQGRLDGTGWATAGGINSTVSLPGGGSGPPEDVKP-PVL-GVRGLHCPPPPGGPGAG-KR
60 70 80 90 100
140 150 160 170 180 190
pF1KB5 ICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQ
.::::::::::::::::::::::::::::::::: :.::::::: .::::::::::::::
XP_005 LCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQ
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB5 KCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESY----
:::. :::::::::::::.... ....: : .. :.:::.:::::::::: :...
XP_005 KCLATGMKREAVQEERQRGKDK-DGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGP
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB5 -GDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIA
: . .: ::::::::.::::::::::::::::::::.: :.::::::::::::::::
XP_005 GGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIA
230 240 250 260 270 280
320 330 340 350 360
pF1KB5 SFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDR----VLTELVSKMKDMQMDKSEL
::::::..:.:::::::::::::.::::::::.:::: :::::::::.::.:::.::
XP_005 SFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTEL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 GCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRS
::::::.::::::::::::::::.:::::::.::.: ::::::: :::::::::::::::
XP_005 GCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRS
350 360 370 380 390 400
430 440 450 460
pF1KB5 IGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
:::::::::::::::::::::::::::::.: :.
XP_005 IGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
410 420 430 440
463 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:23:32 2016 done: Sat Nov 5 15:23:33 2016
Total Scan time: 10.380 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]